AT353274B - Verfahren zur herstellung von 2-substituierten 1,4-benzodiazepinen und deren saeureadditions- verbindungen - Google Patents

Verfahren zur herstellung von 2-substituierten 1,4-benzodiazepinen und deren saeureadditions- verbindungen

Info

Publication number
AT353274B
AT353274B AT335776A AT335776A AT353274B AT 353274 B AT353274 B AT 353274B AT 335776 A AT335776 A AT 335776A AT 335776 A AT335776 A AT 335776A AT 353274 B AT353274 B AT 353274B
Authority
AT
Austria
Prior art keywords
benzodiazepines
substituted
producing
acid addition
addition compounds
Prior art date
Application number
AT335776A
Other languages
English (en)
Other versions
ATA335776A (de
Inventor
Horst Dr Zeugner
Rolf Dr Hueschens
Hans Dr Liepmann
Wolfgang Dr Milkowski
Renke Dr Budden
Siegfried Dr Funke
Werner Dr Stuehmer
Original Assignee
Kali Chemie Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kali Chemie Ag filed Critical Kali Chemie Ag
Publication of ATA335776A publication Critical patent/ATA335776A/de
Application granted granted Critical
Publication of AT353274B publication Critical patent/AT353274B/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D245/00—Heterocyclic compounds containing rings of more than seven members having two nitrogen atoms as the only ring hetero atoms
    • C07D245/04—Heterocyclic compounds containing rings of more than seven members having two nitrogen atoms as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • C07D245/06—Heterocyclic compounds containing rings of more than seven members having two nitrogen atoms as the only ring hetero atoms condensed with carbocyclic rings or ring systems condensed with one six-membered ring

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT335776A 1975-05-10 1976-05-07 Verfahren zur herstellung von 2-substituierten 1,4-benzodiazepinen und deren saeureadditions- verbindungen AT353274B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2520937A DE2520937C3 (de) 1975-05-10 1975-05-10 7-Brom-1 -methyl^-alkoxymethyl-S-(2-halogenphenyl)-lH-23-dihydro-l,4benzodiazepinderivate, deren Säureadditionssalze und pharmazeutische Präparate

Publications (2)

Publication Number Publication Date
ATA335776A ATA335776A (de) 1979-04-15
AT353274B true AT353274B (de) 1979-11-12

Family

ID=5946275

Family Applications (1)

Application Number Title Priority Date Filing Date
AT335776A AT353274B (de) 1975-05-10 1976-05-07 Verfahren zur herstellung von 2-substituierten 1,4-benzodiazepinen und deren saeureadditions- verbindungen

Country Status (28)

Country Link
JP (2) JPS51149293A (de)
AR (1) AR209361A1 (de)
AT (1) AT353274B (de)
AU (1) AU498994B2 (de)
BE (1) BE841549A (de)
CA (1) CA1063107A (de)
CH (1) CH626076A5 (de)
CS (1) CS193075B2 (de)
DD (1) DD124600A5 (de)
DE (1) DE2520937C3 (de)
DK (1) DK145930C (de)
ES (1) ES447737A1 (de)
FI (2) FI62072C (de)
FR (1) FR2310765A1 (de)
GB (1) GB1477999A (de)
GR (1) GR60311B (de)
HU (1) HU174020B (de)
IL (1) IL49548A (de)
MX (1) MX3903E (de)
NL (1) NL187631C (de)
NO (1) NO146238C (de)
NZ (1) NZ180812A (de)
PH (1) PH14964A (de)
PT (1) PT65083B (de)
SE (1) SE422938B (de)
SU (1) SU1126209A3 (de)
YU (1) YU117076A (de)
ZA (1) ZA762785B (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2720968C2 (de) * 1977-05-10 1986-05-07 Kali-Chemie Pharma Gmbh, 3000 Hannover N↓1↓-Acyl-2-hydroxy-1,3-diaminopropane und Arzneimittel
DE2835708A1 (de) 1978-08-16 1980-03-06 Kali Chemie Pharma Gmbh Neue eckige klammer auf 1,2 eckige klammer zu-anellierte 7-phenyl-1,4-benzodiazepinderivate, verfahren zu deren herstellung und arzneimittel
DE3138769A1 (de) * 1981-09-30 1983-04-14 Kali-Chemie Pharma Gmbh, 3000 Hannover 7-brom-5-(2-halogenphenyl)-1h-2,3-dihydro-1,4- benzodiazepin-verbindungen sowie verfahren und zwischenprodukte zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
JP4940065B2 (ja) * 2007-08-29 2012-05-30 トヨタ紡織株式会社 グリースの塗布方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2221558C2 (de) * 1972-05-03 1982-12-02 Kali-Chemie Ag, 3000 Hannover 5-Phenyl-2,3-dihydro-1H-1,4-benzodiazepine und ihre Säureadditionssalze, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel

Also Published As

Publication number Publication date
DE2520937B2 (de) 1978-02-16
FI62072C (fi) 1982-11-10
PT65083B (en) 1977-09-14
JPS51149293A (en) 1976-12-22
PH14964A (en) 1982-02-05
GR60311B (en) 1978-05-08
DK145930B (da) 1983-04-18
SE422938B (sv) 1982-04-05
BE841549A (fr) 1976-09-01
NZ180812A (en) 1978-03-06
MX3903E (es) 1981-09-11
DK145930C (da) 1983-09-26
SE7605200L (sv) 1976-11-11
DE2520937A1 (de) 1976-11-18
DE2520937C3 (de) 1978-10-12
CA1063107A (en) 1979-09-25
GB1477999A (en) 1977-06-29
ES447737A1 (es) 1977-06-01
FR2310765A1 (fr) 1976-12-10
HU174020B (hu) 1979-10-28
CS193075B2 (en) 1979-09-17
AR209361A1 (es) 1977-04-15
FI813680L (fi) 1981-11-19
CH626076A5 (en) 1981-10-30
FI761284A (de) 1976-11-11
AU1377976A (en) 1977-11-17
NO146238B (no) 1982-05-18
JPS6212222B2 (de) 1987-03-17
FI62072B (fi) 1982-07-30
YU117076A (en) 1982-08-31
JPS61178970A (ja) 1986-08-11
AU498994B2 (en) 1979-03-29
NL7604974A (nl) 1976-11-12
NO146238C (no) 1982-08-25
DD124600A5 (de) 1977-03-02
IL49548A (en) 1980-02-29
NL187631C (nl) 1991-12-02
SU1126209A3 (ru) 1984-11-23
ATA335776A (de) 1979-04-15
DK205676A (da) 1976-11-11
PT65083A (en) 1976-06-01
FR2310765B1 (de) 1979-07-13
NO761581L (de) 1976-11-11
IL49548A0 (en) 1976-07-30
ZA762785B (en) 1977-04-27

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