EG12387A - Process for preparing of piperazinyl pyrazines - Google Patents

Process for preparing of piperazinyl pyrazines

Info

Publication number
EG12387A
EG12387A EG76205A EG20576A EG12387A EG 12387 A EG12387 A EG 12387A EG 76205 A EG76205 A EG 76205A EG 20576 A EG20576 A EG 20576A EG 12387 A EG12387 A EG 12387A
Authority
EG
Egypt
Prior art keywords
preparing
pyrazines
piperazinyl
piperazinyl pyrazines
Prior art date
Application number
EG76205A
Inventor
W Lumma
W Saari
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Application granted granted Critical
Publication of EG12387A publication Critical patent/EG12387A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D241/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D241/20—Nitrogen atoms
EG76205A 1975-04-21 1976-04-07 Process for preparing of piperazinyl pyrazines EG12387A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US57005275A 1975-04-21 1975-04-21

Publications (1)

Publication Number Publication Date
EG12387A true EG12387A (en) 1978-12-31

Family

ID=24277994

Family Applications (1)

Application Number Title Priority Date Filing Date
EG76205A EG12387A (en) 1975-04-21 1976-04-07 Process for preparing of piperazinyl pyrazines

Country Status (36)

Country Link
JP (1) JPS51136688A (en)
AR (1) AR210349A1 (en)
AT (1) AT353795B (en)
AU (1) AU496854B2 (en)
BE (1) BE840904A (en)
BG (1) BG34185A3 (en)
CA (1) CA1059128A (en)
CH (1) CH619462A5 (en)
CS (1) CS195726B2 (en)
CY (1) CY1090A (en)
DD (1) DD124599A5 (en)
DE (1) DE2617205C3 (en)
DK (1) DK143899C (en)
EG (1) EG12387A (en)
ES (4) ES447150A1 (en)
FI (1) FI62666C (en)
FR (1) FR2308367A1 (en)
GB (1) GB1492528A (en)
GR (1) GR59900B (en)
HK (1) HK60380A (en)
HU (1) HU172684B (en)
IE (1) IE42979B1 (en)
IL (1) IL49391A (en)
KE (1) KE3088A (en)
LU (1) LU74795A1 (en)
MY (1) MY8100225A (en)
NL (1) NL167692C (en)
NO (1) NO146599C (en)
PH (1) PH12274A (en)
PL (1) PL99664B1 (en)
PT (1) PT65027B (en)
RO (1) RO73278A (en)
SE (1) SE421695B (en)
SU (1) SU638260A3 (en)
YU (1) YU100676A (en)
ZA (1) ZA762320B (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4091098A (en) * 1977-04-25 1978-05-23 Merck & Co., Inc. 3-(1-PIPERAZINYL)-1,2,4-BENZOTRIAZINES AND N-oxides
US4163849A (en) 1978-03-17 1979-08-07 Merck & Co., Inc. Piperazinylpyrazines
US4252816A (en) * 1979-12-03 1981-02-24 Merck & Co., Inc. Tetrahydro-1H-1,4-diazepino(1,7-a)benzimidazoles useful as analgesic agents
US4339579A (en) 1980-12-29 1982-07-13 American Home Products Corporation 2,6-Bis-(pyrrolopyrazinyl)pyrazines
EP0094498A3 (en) * 1982-05-06 1985-04-03 American Cyanamid Company Antiatherosclerotic 1-piperazine derivatives
US4547505A (en) * 1983-03-25 1985-10-15 Degussa Aktiengesellschaft N-Phenyl-N-'-cycloalkylalkanoylpiperazine useful as analgetics and process for its production
US4788290A (en) * 1987-12-11 1988-11-29 American Home Products Corporation Serotonergic pyrazine derivatives
EP0580465A1 (en) * 1992-06-25 1994-01-26 Sanofi New therapeutic use of heterocyclic piperazines as 5-HT3 agonists and new derivatives
WO1999021834A1 (en) * 1997-10-27 1999-05-06 Neurosearch A/S Heteroaryl diazacycloalkanes as cholinergic ligands at nicotinic acetylcholine receptors
AU773830B2 (en) 1999-04-26 2004-06-10 Neurosearch A/S Heteroaryl diazacycloalkanes, their preparation and use
SK11542002A3 (en) * 2000-02-16 2003-03-04 Neurogen Corporation Substituted arylpyrazines
US6825198B2 (en) * 2001-06-21 2004-11-30 Pfizer Inc 5-HT receptor ligands and uses thereof
EP1534391B1 (en) * 2002-07-19 2007-02-14 Biovitrum AB Novel piperazinyl-pyrazinone derivatives for the treatment of 5-ht2a receptor-related disorders
SE0202287D0 (en) * 2002-07-19 2002-07-19 Biovitrum Ab New compounds

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2606906A (en) * 1948-10-14 1952-08-12 American Cyanamid Co 1-(2-pyridyl) piperazine and process of preparing same

Also Published As

Publication number Publication date
HK60380A (en) 1980-11-07
GB1492528A (en) 1977-11-23
PH12274A (en) 1978-12-12
DE2617205B2 (en) 1980-05-08
IL49391A (en) 1979-09-30
DK143899C (en) 1982-04-13
IE42979B1 (en) 1980-11-19
DK143899B (en) 1981-10-26
DK164476A (en) 1976-10-22
CY1090A (en) 1980-12-27
ES459406A1 (en) 1978-08-16
NL167692C (en) 1982-01-18
BE840904A (en) 1976-08-16
IE42979L (en) 1976-10-21
AT353795B (en) 1979-12-10
CH619462A5 (en) 1980-09-30
PL99664B1 (en) 1978-07-31
GR59900B (en) 1978-03-16
LU74795A1 (en) 1977-02-07
NO761207L (en) 1976-10-22
BG34185A3 (en) 1983-07-15
ZA762320B (en) 1977-11-30
NO146599B (en) 1982-07-26
DE2617205A1 (en) 1976-10-28
HU172684B (en) 1978-11-28
FR2308367B1 (en) 1979-09-21
NO146599C (en) 1982-11-03
CS195726B2 (en) 1980-02-29
PT65027B (en) 1978-04-03
DE2617205C3 (en) 1981-01-29
NL7603800A (en) 1976-10-25
SU638260A3 (en) 1978-12-15
KE3088A (en) 1980-11-07
AU1296676A (en) 1977-10-20
JPS51136688A (en) 1976-11-26
AR210349A1 (en) 1977-07-29
JPS5522475B2 (en) 1980-06-17
FI62666C (en) 1983-02-10
DD124599A5 (en) 1977-03-02
MY8100225A (en) 1981-12-31
PT65027A (en) 1976-05-01
ES459405A1 (en) 1978-08-16
FI760978A (en) 1976-10-22
SE421695B (en) 1982-01-25
YU100676A (en) 1982-08-31
ES447150A1 (en) 1977-09-16
CA1059128A (en) 1979-07-24
ES459407A1 (en) 1978-08-16
AU496854B2 (en) 1978-11-02
NL167692B (en) 1981-08-17
RO73278A (en) 1982-09-09
SE7604093L (en) 1976-10-22
ATA288376A (en) 1979-05-15
FR2308367A1 (en) 1976-11-19
FI62666B (en) 1982-10-29
IL49391A0 (en) 1976-06-30

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