AT351025B - Verfahren zur herstellung von neuen 1,4-dihydro -pyridinen und deren salzen - Google Patents

Verfahren zur herstellung von neuen 1,4-dihydro -pyridinen und deren salzen

Info

Publication number
AT351025B
AT351025B AT568776A AT568776A AT351025B AT 351025 B AT351025 B AT 351025B AT 568776 A AT568776 A AT 568776A AT 568776 A AT568776 A AT 568776A AT 351025 B AT351025 B AT 351025B
Authority
AT
Austria
Prior art keywords
pyridines
dihydro
salts
new
production
Prior art date
Application number
AT568776A
Other languages
English (en)
Other versions
ATA568776A (de
Inventor
Jean-Marie Teulon
Bernard Schweisguth
Jean-Claude Cognacq
Original Assignee
Hexachimie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB33501/75A external-priority patent/GB1511694A/en
Application filed by Hexachimie filed Critical Hexachimie
Publication of ATA568776A publication Critical patent/ATA568776A/de
Application granted granted Critical
Publication of AT351025B publication Critical patent/AT351025B/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/70—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cardiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
AT568776A 1975-08-12 1976-08-02 Verfahren zur herstellung von neuen 1,4-dihydro -pyridinen und deren salzen AT351025B (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB33501/75A GB1511694A (en) 1975-08-12 1975-08-12 Pyridine derivatives
GB4518875 1975-10-31

Publications (2)

Publication Number Publication Date
ATA568776A ATA568776A (de) 1978-12-15
AT351025B true AT351025B (de) 1979-07-10

Family

ID=26261898

Family Applications (1)

Application Number Title Priority Date Filing Date
AT568776A AT351025B (de) 1975-08-12 1976-08-02 Verfahren zur herstellung von neuen 1,4-dihydro -pyridinen und deren salzen

Country Status (19)

Country Link
US (1) US4096270A (de)
JP (1) JPS5223081A (de)
AR (1) AR209672A1 (de)
AT (1) AT351025B (de)
AU (1) AU504839B2 (de)
CA (1) CA1079284A (de)
CH (1) CH612678A5 (de)
CS (1) CS194774B2 (de)
DD (1) DD126696A5 (de)
DE (1) DE2635916A1 (de)
DK (1) DK362676A (de)
ES (1) ES450582A1 (de)
FR (1) FR2320750A1 (de)
MX (1) MX3464E (de)
NL (1) NL7608989A (de)
NO (1) NO144457C (de)
PT (1) PT65456B (de)
SE (1) SE7608959L (de)
SU (1) SU1007556A3 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH639659A5 (de) * 1978-12-18 1983-11-30 Sandoz Ag Neue 1,4-dihydropyridinderivate, deren herstellung und verwendung.
DE2738153A1 (de) * 1977-08-24 1979-03-08 Bayer Ag 2-pyridyl-1,4-dihydropyridine, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
DE2949464A1 (de) * 1978-12-18 1980-06-26 Sandoz Ag Benzoxadiazole und benzothiadiazole, ihre herstellung und verwendung
US4497808A (en) * 1981-12-30 1985-02-05 Ciba-Geigy Corporation N-Oxide compounds useful in the treatment of cardiovascular ailments
DE3207982A1 (de) * 1982-03-05 1983-09-08 Bayer Ag, 5090 Leverkusen Neue 1,4-dihydropyridine, verfahren zu ihrer herstellung und ihrer verwendung in arzneimitteln
US4414213A (en) * 1982-03-22 1983-11-08 Mead Johnson & Company Dihydropyridyl cyclic imidate esters and their pharmaceutical use
US4771057A (en) * 1986-02-03 1988-09-13 University Of Alberta Reduced pyridyl derivatives with cardiovascular regulating properties
DE4236707A1 (de) * 1992-10-30 1994-05-05 Bayer Ag 4-Heterocyclyl substituierte Dihydropyridine
US6001857A (en) * 1992-10-30 1999-12-14 Bayer Aktiengesellschaft Heterocyclyl substituted dihydropyridines

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1670824C3 (de) * 1967-03-20 1978-08-03 Bayer Ag, 5090 Leverkusen 1,4-Dihydropyridin-33-dicarbonsäurealkylester
DE1813436C3 (de) * 1968-12-07 1979-01-11 Bayer Ag, 5090 Leverkusen N-Substituierte 2,6-Dimethyl-l,4dihydropyridine
DE1923990C3 (de) * 1969-05-10 1978-11-23 Bayer Ag Verfahren zur Herstellung von N-substituierten M-Dihydropyridin-S.S-dicarbonsäureestern
ZA7152B (en) * 1970-01-24 1971-10-27 Bayer Ag New pharmaceutically active 1,4-dihydropyridines
DE2005116C3 (de) * 1970-02-05 1980-02-14 Bayer Ag, 5090 Leverkusen Symmetrische 1,4-Dihydropyridin-3,5-dicarbonsäureester
DE2117573C3 (de) * 1971-04-10 1978-07-27 Bayer Ag, 5090 Leverkusen Verfahren zur Herstellung von unsymmetrischen l,4-Dihydropyridin-3,5dicarbonsäureestern, sowie ihre Verwendung als Arzneimittel
DE2117571C3 (de) * 1971-04-10 1979-10-11 Bayer Ag, 5090 Leverkusen Unsymmetrische 1,4-Dihydropyridin-33-dicarbonsäureester, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel
DE2210672C3 (de) * 1972-03-06 1980-03-20 Bayer Ag, 5090 Leverkusen N-substituierte unsymmetrische 1 ^-Dihydropyridin-S^-dicarbonsäureester, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel
DE2218644C3 (de) * 1972-04-18 1982-08-19 Bayer Ag, 5090 Leverkusen Basische Ester von 1,4-Dihydropyridinen, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel
DE2248150A1 (de) * 1972-09-30 1974-04-04 Bayer Ag Dihydropyridinpolyester, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel

Also Published As

Publication number Publication date
AR209672A1 (es) 1977-05-13
US4096270A (en) 1978-06-20
SU1007556A3 (ru) 1983-03-23
NO144457C (no) 1981-09-02
PT65456B (fr) 1978-02-10
CS194774B2 (en) 1979-12-31
ATA568776A (de) 1978-12-15
PT65456A (fr) 1976-09-01
NO762790L (de) 1977-02-15
AU504839B2 (en) 1979-11-01
MX3464E (es) 1980-12-09
FR2320750A1 (fr) 1977-03-11
JPS5223081A (en) 1977-02-21
SE7608959L (sv) 1977-02-13
CH612678A5 (de) 1979-08-15
DD126696A5 (de) 1977-08-03
ES450582A1 (es) 1977-11-16
DE2635916A1 (de) 1977-02-24
NL7608989A (nl) 1977-02-15
FR2320750B1 (de) 1979-09-28
DK362676A (da) 1977-02-13
AU1656976A (en) 1978-02-09
CA1079284A (en) 1980-06-10
JPS5422986B2 (de) 1979-08-10
NO144457B (no) 1981-05-25

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Legal Events

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ELJ Ceased due to non-payment of the annual fee
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties