AT344332B - Verfahren zur herstellung neuer 2-tetrahydrofurfuryl-6,7-benzomorphane und deren saeureadditionssalzen - Google Patents

Verfahren zur herstellung neuer 2-tetrahydrofurfuryl-6,7-benzomorphane und deren saeureadditionssalzen

Info

Publication number
AT344332B
AT344332B AT153875A AT153875A AT344332B AT 344332 B AT344332 B AT 344332B AT 153875 A AT153875 A AT 153875A AT 153875 A AT153875 A AT 153875A AT 344332 B AT344332 B AT 344332B
Authority
AT
Austria
Prior art keywords
benzomorphanes
tetrahydrofurfuryl
acid addition
addition salts
producing new
Prior art date
Application number
AT153875A
Other languages
German (de)
English (en)
Other versions
ATA153875A (de
Original Assignee
Boehringer Sohn Ingelheim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Sohn Ingelheim filed Critical Boehringer Sohn Ingelheim
Publication of ATA153875A publication Critical patent/ATA153875A/de
Application granted granted Critical
Publication of AT344332B publication Critical patent/AT344332B/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22—Bridged ring systems
    • C07D221/26—Benzomorphans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT153875A 1974-03-09 1975-02-28 Verfahren zur herstellung neuer 2-tetrahydrofurfuryl-6,7-benzomorphane und deren saeureadditionssalzen AT344332B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2411382A DE2411382C3 (de) 1974-03-09 1974-03-09 2-Tetrahydrofurfuryl-6,7-benzomorphane, Verfahren zur Herstellung und deren Verwendung

Publications (2)

Publication Number Publication Date
ATA153875A ATA153875A (de) 1977-11-15
AT344332B true AT344332B (de) 1978-07-10

Family

ID=5909593

Family Applications (1)

Application Number Title Priority Date Filing Date
AT153875A AT344332B (de) 1974-03-09 1975-02-28 Verfahren zur herstellung neuer 2-tetrahydrofurfuryl-6,7-benzomorphane und deren saeureadditionssalzen

Country Status (25)

Country Link
JP (1) JPS5827275B2 (ja)
AT (1) AT344332B (ja)
BE (1) BE826440A (ja)
BG (3) BG24814A4 (ja)
CA (1) CA1049511A (ja)
CH (8) CH612425A5 (ja)
CS (1) CS188221B2 (ja)
DD (1) DD119236A5 (ja)
DE (1) DE2411382C3 (ja)
DK (1) DK137188C (ja)
ES (6) ES440348A1 (ja)
FI (1) FI63571C (ja)
FR (1) FR2262984B1 (ja)
GB (1) GB1496418A (ja)
HU (1) HU177408B (ja)
IE (1) IE40945B1 (ja)
IL (1) IL46760A (ja)
NL (1) NL7502724A (ja)
NO (1) NO141800C (ja)
PH (1) PH14127A (ja)
PL (3) PL93700B1 (ja)
RO (2) RO69617A (ja)
SE (1) SE421919B (ja)
SU (3) SU577982A3 (ja)
ZA (1) ZA751394B (ja)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2716687A1 (de) * 1977-04-15 1978-10-19 Boehringer Sohn Ingelheim 2'-hydroxy-2-(5-isoxazolylmethyl)-6,7benzomorphane, deren saeureadditionssalze und diese enthaltende arzneimittel
DE2828039A1 (de) * 1978-06-26 1980-01-10 Boehringer Sohn Ingelheim 2-(2-alkoxyethyl)-2'-hydroxy-6,7-benzomorphane deren saeureadditionssalze diese enthaltende arzneimittel und verfahren zu deren herstellung
US6492420B2 (en) 1995-03-10 2002-12-10 Photocure As Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy
US6992107B1 (en) 1995-03-10 2006-01-31 Photocure Asa Esters of 5-aminolevulinic acid and their use as photosensitizing compounds in photochemotherapy
US7530461B2 (en) 1995-03-10 2009-05-12 Photocure Asa Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy
CZ291132B6 (cs) * 1995-03-10 2002-12-11 Photocure Asa Estery kyselin 5-aminolevulových a farmaceutický prostředek s jejich obsahem
GB0018528D0 (en) 2000-07-27 2000-09-13 Photocure Asa Compounds
US6723750B2 (en) 2002-03-15 2004-04-20 Allergan, Inc. Photodynamic therapy for pre-melanomas
ES2395081T3 (es) 2007-07-26 2013-02-08 Vitae Pharmaceuticals, Inc. Síntesis de inhibidores de la 11beta-hidroxiesteroide deshidrogenasa de tipo 1
TW200927115A (en) 2007-11-16 2009-07-01 Boehringer Ingelheim Int Aryl-and heteroarylcarbonyl derivatives of benzomorphanes and related scaffolds, medicaments containing such compounds and their use
EP2229368A1 (en) 2007-12-11 2010-09-22 Vitae Pharmaceuticals, Inc. Cyclic urea inhibitors of 11beta-hydroxysteroid dehydrogenase 1
TW200934490A (en) 2008-01-07 2009-08-16 Vitae Pharmaceuticals Inc Lactam inhibitors of 11 &abgr;-hydroxysteroid dehydrogenase 1
JP5490020B2 (ja) 2008-01-24 2014-05-14 ヴァイティー ファーマシューティカルズ，インコーポレイテッド １１β−ヒドロキシステロイドデヒドロゲナーゼ１の環状カルバゼート及びセミカルバジドインヒビター
CA2715290A1 (en) 2008-02-15 2009-08-20 Vitae Pharmaceuticals, Inc. Inhibitors of 11beta-hydroxysteroid dehydrogenase 1
WO2009134392A1 (en) 2008-05-01 2009-11-05 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
WO2009134387A1 (en) 2008-05-01 2009-11-05 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
JP5301563B2 (ja) 2008-05-01 2013-09-25 ヴァイティー ファーマシューティカルズ，インコーポレイテッド １１β−ヒドロキシステロイドデヒドロゲナーゼ１の環状インヒビター
CL2009001151A1 (es) 2008-05-13 2010-08-13 Boehringer Ingelheim Int Compuestos derivados de acidos carbociclicos aliciclicos de benzomorfanos, procedimiento de preparacion, composicion farmaceutica, utiles para tratar enfermedades influenciadas por la inhibicion de la enzima 11beta-hidroxiesteroide deshidrogenasa, como trastornos metabolicos.
CA2729998A1 (en) 2008-07-25 2010-01-28 Boehringer Ingelheim International Gmbh Inhibitors of 11beta-hydroxysteroid dehydrogenase 1
EP2324018B1 (en) 2008-07-25 2013-09-04 Boehringer Ingelheim International GmbH Cyclic inhibitors of 11 beta-hydroxysteroid dehydrogenase 1
MA33216B1 (fr) 2009-04-30 2012-04-02 Boehringer Ingelheim Int Inhibiteurs cycliques de la 11béta-hydroxysteroïde déshydrogénase 1
US8927539B2 (en) 2009-06-11 2015-01-06 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11β-hydroxysteroid dehydrogenase 1 based on the 1,3-oxazinan-2-one structure
AR078887A1 (es) 2009-11-06 2011-12-07 Boehringer Ingelheim Int Derivados arilo y heteroarilcarbonilo de hexahidroindenopiridina y octahidrobenzoquinolina y composiciones farmaceuticas que los contienen.
EP2582698B1 (en) 2010-06-16 2016-09-14 Vitae Pharmaceuticals, Inc. Substituted 5-,6- and 7-membered heterocycles, medicaments containing such compounds, and their use
TWI537258B (zh) 2010-11-05 2016-06-11 百靈佳殷格翰國際股份有限公司 六氫茚并吡啶及八氫苯并喹啉之芳基－及雜環芳基羰基衍生物
WO2013025664A1 (en) 2011-08-17 2013-02-21 Boehringer Ingelheim International Gmbh Indenopyridine derivatives

Also Published As

Publication number Publication date
IL46760A (en) 1978-12-17
SU577983A3 (ru) 1977-10-25
SE7502592L (ja) 1975-09-10
JPS50123675A (ja) 1975-09-29
PL93700B1 (ja) 1977-06-30
JPS5827275B2 (ja) 1983-06-08
RO70051A (ro) 1980-12-30
ZA751394B (en) 1976-11-24
DE2411382B2 (de) 1979-01-18
FI63571B (fi) 1983-03-31
IE40945B1 (en) 1979-09-12
CH620439A5 (en) 1980-11-28
FR2262984B1 (ja) 1978-07-28
DE2411382C3 (de) 1979-09-06
FR2262984A1 (ja) 1975-10-03
PL93499B1 (ja) 1977-05-30
BG24813A4 (en) 1978-05-12
IL46760A0 (en) 1975-05-22
CH620440A5 (en) 1980-11-28
ATA153875A (de) 1977-11-15
CH622016A5 (en) 1981-03-13
IE40945L (en) 1975-09-09
FI63571C (fi) 1983-07-11
FI750652A (ja) 1975-09-10
ES440350A1 (es) 1977-03-16
CH622015A5 (en) 1981-03-13
DK137188B (da) 1978-01-30
NL7502724A (nl) 1975-09-11
CH622017A5 (en) 1981-03-13
SU588916A3 (ru) 1978-01-15
BG24814A4 (en) 1978-05-12
PH14127A (en) 1981-02-26
ES440349A1 (es) 1977-03-01
ES440347A1 (es) 1977-06-01
BE826440A (fr) 1975-09-08
CH620681A5 (en) 1980-12-15
BG25087A3 (en) 1978-07-12
DE2411382A1 (de) 1975-09-18
RO69617A (ro) 1980-08-15
HU177408B (en) 1981-10-28
NO141800B (no) 1980-02-04
DK137188C (da) 1978-07-03
ES440346A1 (es) 1977-03-01
SU577982A3 (ru) 1977-10-25
PL93699B1 (ja) 1977-06-30
NO750773L (ja) 1975-09-10
CH612425A5 (en) 1979-07-31
ES440345A1 (es) 1977-03-01
DK92975A (ja) 1975-09-10
NO141800C (no) 1980-06-04
SE421919B (sv) 1982-02-08
GB1496418A (en) 1977-12-30
CH622014A5 (en) 1981-03-13
AU7894275A (en) 1976-09-16
ES440348A1 (es) 1977-06-01
CS188221B2 (en) 1979-02-28
CA1049511A (en) 1979-02-27
DD119236A5 (ja) 1976-04-12

Similar Documents

Publication Publication Date Title
AT344332B (de) Verfahren zur herstellung neuer 2-tetrahydrofurfuryl-6,7-benzomorphane und deren saeureadditionssalzen
AT348140B (de) Verfahren zur herstellung neuer, 5,9-beta- disubstituierter 2-tetrahydrofurfuryl-6,7-benzomorphane und deren saeureadditionssalzen
AT340916B (de) Verfahren zur herstellung neuer 1,1-diaryl-1-oxadiazol-alkylamine und deren nicht-toxischen salze
AT351547B (de) Verfahren zur herstellung von neuen thieno- (1,5)-benzodiazepinen und deren saeure- additionssalzen
AT344889B (de) Verfahren zur herstellung von neuen 7-methoxy-6-thiatetracyclinen und deren salzen
AT342058B (de) Verfahren zur herstellung neuer pyridobenzodiazepinone und ihrer salze
AT344159B (de) Verfahren zur herstellung neuer 2,6-disubstituierter 2-phenylimino-imidazolidine und ihrer saeureadditionssalze
AT344142B (de) Verfahren zur herstellung von neuen substituierten 3-phenoxy-2-hydroxy-1-aminopropanen und deren saeureadditionssalzen
AT350737B (de) Verfahren zur herstellung neuer n-tetrahydro- furfuryl-noroxymorphone und deren saeure- additionssalzen
AT342599B (de) Verfahren zur herstellung von neuen indolobenzazepinen und deren saureadditionssalzen
AT346840B (de) Verfahren zur herstellung neuer 1-amino-3- phenyl-indolderivate und ihrer salze
AT344704B (de) Verfahren zur herstellung von neuen benzylpyrimidinen und von deren salzen
AT357147B (de) Verfahren zur herstellung neuer indolderivate und ihrer salze
AT357545B (de) Verfahren zur herstellung neuer 5,5,7,7-tetra- methylfuro(3,4-e)as-triazine und ihrer saeure- additionssalze
ATA966475A (de) Verfahren zur herstellung neuer diazepinoiso- chinoline und ihrer saeureadditionssalze
AT344691B (de) Verfahren zur herstellung neuer thiazol-5-carbonsaeurederivate und ihrer salze
AT358196B (de) Verfahren zur herstellung neuer n-tetrahydro- furfuryl-noroxymorphone und deren saeure- additionssalzen
ATA829776A (de) Verfahren zur herstellung neuer 2-tetrahydrofurfuryl-6,7-benzomorphane und deren saeureadditionssalzen
AT329537B (de) Verfahren zur herstellung neuer halogenierter hydroxybenzylamine sowie deren saureadditionssalze
ATA559977A (de) Verfahren zur herstellung neuer 5,9-beta- disubstituierter 2-tetrahydrofurfuryl-6,7- benzomorphane und deren saeureadditionssalze
ATA576279A (de) Verfahren zur herstellung neuer,basisch substi- tuierter indolderivate und deren saeure- additionssalze
ATA612578A (de) Verfahren zur herstellung neuer indolderivate und ihrer salze
ATA421177A (de) Verfahren zur herstellung neuer 2,6-di- subsitutierter 2-phenylimino-imidazolidine und deren saeureadditionssalze

Legal Events

Date Code Title Description
ELJ Ceased due to non-payment of the annual fee
REN Ceased due to non-payment of the annual fee