ES440348A1 - Procedimiento para la preparacion de 2-tetrahidrofurfuril-6,7-benzomorfanos. - Google Patents

Procedimiento para la preparacion de 2-tetrahidrofurfuril-6,7-benzomorfanos.

Info

Publication number
ES440348A1
ES440348A1 ES440348A ES440348A ES440348A1 ES 440348 A1 ES440348 A1 ES 440348A1 ES 440348 A ES440348 A ES 440348A ES 440348 A ES440348 A ES 440348A ES 440348 A1 ES440348 A1 ES 440348A1
Authority
ES
Spain
Prior art keywords
methyl
formula
action
denotes hydrogen
morphine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES440348A
Other languages
English (en)
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CH Boehringer Sohn AG and Co KG
Original Assignee
CH Boehringer Sohn AG and Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CH Boehringer Sohn AG and Co KG filed Critical CH Boehringer Sohn AG and Co KG
Publication of ES440348A1 publication Critical patent/ES440348A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22—Bridged ring systems
    • C07D221/26—Benzomorphans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
ES440348A 1974-03-09 1975-08-20 Procedimiento para la preparacion de 2-tetrahidrofurfuril-6,7-benzomorfanos. Expired ES440348A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2411382A DE2411382C3 (de) 1974-03-09 1974-03-09 2-Tetrahydrofurfuryl-6,7-benzomorphane, Verfahren zur Herstellung und deren Verwendung

Publications (1)

Publication Number Publication Date
ES440348A1 true ES440348A1 (es) 1977-06-01

Family

ID=5909593

Family Applications (6)

Application Number Title Priority Date Filing Date
ES440348A Expired ES440348A1 (es) 1974-03-09 1975-08-20 Procedimiento para la preparacion de 2-tetrahidrofurfuril-6,7-benzomorfanos.
ES440346A Expired ES440346A1 (es) 1974-03-09 1975-08-20 Procedimiento para la preparacion de 2-tetrahidrofurfuril-6,7-benzomorfanos.
ES440349A Expired ES440349A1 (es) 1974-03-09 1975-08-20 Procedimiento para la preparacion de 2-tetrahidrofurfuril-6,7-benzomorfanos.
ES440347A Expired ES440347A1 (es) 1974-03-09 1975-08-20 Procedimiento para la preparacion de 2-tetrahidrofurfuril-6,7-benzomorfanos.
ES440345A Expired ES440345A1 (es) 1974-03-09 1975-08-20 Procedimiento para la preparacion de 2-tetrahidrofurfuril-6,7-benzomorfanos.
ES440350A Expired ES440350A1 (es) 1974-03-09 1975-08-20 Procedimiento para la preparacion de 2-tetrahidrofurfuril-6,7-benzomorfanos.

Family Applications After (5)

Application Number Title Priority Date Filing Date
ES440346A Expired ES440346A1 (es) 1974-03-09 1975-08-20 Procedimiento para la preparacion de 2-tetrahidrofurfuril-6,7-benzomorfanos.
ES440349A Expired ES440349A1 (es) 1974-03-09 1975-08-20 Procedimiento para la preparacion de 2-tetrahidrofurfuril-6,7-benzomorfanos.
ES440347A Expired ES440347A1 (es) 1974-03-09 1975-08-20 Procedimiento para la preparacion de 2-tetrahidrofurfuril-6,7-benzomorfanos.
ES440345A Expired ES440345A1 (es) 1974-03-09 1975-08-20 Procedimiento para la preparacion de 2-tetrahidrofurfuril-6,7-benzomorfanos.
ES440350A Expired ES440350A1 (es) 1974-03-09 1975-08-20 Procedimiento para la preparacion de 2-tetrahidrofurfuril-6,7-benzomorfanos.

Country Status (25)

Country Link
JP (1) JPS5827275B2 (ja)
AT (1) AT344332B (ja)
BE (1) BE826440A (ja)
BG (3) BG24814A4 (ja)
CA (1) CA1049511A (ja)
CH (8) CH612425A5 (ja)
CS (1) CS188221B2 (ja)
DD (1) DD119236A5 (ja)
DE (1) DE2411382C3 (ja)
DK (1) DK137188C (ja)
ES (6) ES440348A1 (ja)
FI (1) FI63571C (ja)
FR (1) FR2262984B1 (ja)
GB (1) GB1496418A (ja)
HU (1) HU177408B (ja)
IE (1) IE40945B1 (ja)
IL (1) IL46760A (ja)
NL (1) NL7502724A (ja)
NO (1) NO141800C (ja)
PH (1) PH14127A (ja)
PL (3) PL93700B1 (ja)
RO (2) RO69617A (ja)
SE (1) SE421919B (ja)
SU (3) SU577982A3 (ja)
ZA (1) ZA751394B (ja)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2716687A1 (de) * 1977-04-15 1978-10-19 Boehringer Sohn Ingelheim 2'-hydroxy-2-(5-isoxazolylmethyl)-6,7benzomorphane, deren saeureadditionssalze und diese enthaltende arzneimittel
DE2828039A1 (de) * 1978-06-26 1980-01-10 Boehringer Sohn Ingelheim 2-(2-alkoxyethyl)-2'-hydroxy-6,7-benzomorphane deren saeureadditionssalze diese enthaltende arzneimittel und verfahren zu deren herstellung
US6492420B2 (en) 1995-03-10 2002-12-10 Photocure As Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy
US6992107B1 (en) 1995-03-10 2006-01-31 Photocure Asa Esters of 5-aminolevulinic acid and their use as photosensitizing compounds in photochemotherapy
US7530461B2 (en) 1995-03-10 2009-05-12 Photocure Asa Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy
CZ291132B6 (cs) * 1995-03-10 2002-12-11 Photocure Asa Estery kyselin 5-aminolevulových a farmaceutický prostředek s jejich obsahem
GB0018528D0 (en) 2000-07-27 2000-09-13 Photocure Asa Compounds
US6723750B2 (en) 2002-03-15 2004-04-20 Allergan, Inc. Photodynamic therapy for pre-melanomas
ES2395081T3 (es) 2007-07-26 2013-02-08 Vitae Pharmaceuticals, Inc. Síntesis de inhibidores de la 11beta-hidroxiesteroide deshidrogenasa de tipo 1
TW200927115A (en) 2007-11-16 2009-07-01 Boehringer Ingelheim Int Aryl-and heteroarylcarbonyl derivatives of benzomorphanes and related scaffolds, medicaments containing such compounds and their use
EP2229368A1 (en) 2007-12-11 2010-09-22 Vitae Pharmaceuticals, Inc. Cyclic urea inhibitors of 11beta-hydroxysteroid dehydrogenase 1
TW200934490A (en) 2008-01-07 2009-08-16 Vitae Pharmaceuticals Inc Lactam inhibitors of 11 &abgr;-hydroxysteroid dehydrogenase 1
JP5490020B2 (ja) 2008-01-24 2014-05-14 ヴァイティー ファーマシューティカルズ，インコーポレイテッド １１β−ヒドロキシステロイドデヒドロゲナーゼ１の環状カルバゼート及びセミカルバジドインヒビター
CA2715290A1 (en) 2008-02-15 2009-08-20 Vitae Pharmaceuticals, Inc. Inhibitors of 11beta-hydroxysteroid dehydrogenase 1
WO2009134392A1 (en) 2008-05-01 2009-11-05 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
WO2009134387A1 (en) 2008-05-01 2009-11-05 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
JP5301563B2 (ja) 2008-05-01 2013-09-25 ヴァイティー ファーマシューティカルズ，インコーポレイテッド １１β−ヒドロキシステロイドデヒドロゲナーゼ１の環状インヒビター
CL2009001151A1 (es) 2008-05-13 2010-08-13 Boehringer Ingelheim Int Compuestos derivados de acidos carbociclicos aliciclicos de benzomorfanos, procedimiento de preparacion, composicion farmaceutica, utiles para tratar enfermedades influenciadas por la inhibicion de la enzima 11beta-hidroxiesteroide deshidrogenasa, como trastornos metabolicos.
CA2729998A1 (en) 2008-07-25 2010-01-28 Boehringer Ingelheim International Gmbh Inhibitors of 11beta-hydroxysteroid dehydrogenase 1
EP2324018B1 (en) 2008-07-25 2013-09-04 Boehringer Ingelheim International GmbH Cyclic inhibitors of 11 beta-hydroxysteroid dehydrogenase 1
MA33216B1 (fr) 2009-04-30 2012-04-02 Boehringer Ingelheim Int Inhibiteurs cycliques de la 11béta-hydroxysteroïde déshydrogénase 1
US8927539B2 (en) 2009-06-11 2015-01-06 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11β-hydroxysteroid dehydrogenase 1 based on the 1,3-oxazinan-2-one structure
AR078887A1 (es) 2009-11-06 2011-12-07 Boehringer Ingelheim Int Derivados arilo y heteroarilcarbonilo de hexahidroindenopiridina y octahidrobenzoquinolina y composiciones farmaceuticas que los contienen.
EP2582698B1 (en) 2010-06-16 2016-09-14 Vitae Pharmaceuticals, Inc. Substituted 5-,6- and 7-membered heterocycles, medicaments containing such compounds, and their use
TWI537258B (zh) 2010-11-05 2016-06-11 百靈佳殷格翰國際股份有限公司 六氫茚并吡啶及八氫苯并喹啉之芳基－及雜環芳基羰基衍生物
WO2013025664A1 (en) 2011-08-17 2013-02-21 Boehringer Ingelheim International Gmbh Indenopyridine derivatives

Also Published As

Publication number Publication date
IL46760A (en) 1978-12-17
SU577983A3 (ru) 1977-10-25
SE7502592L (ja) 1975-09-10
JPS50123675A (ja) 1975-09-29
PL93700B1 (ja) 1977-06-30
JPS5827275B2 (ja) 1983-06-08
RO70051A (ro) 1980-12-30
ZA751394B (en) 1976-11-24
DE2411382B2 (de) 1979-01-18
FI63571B (fi) 1983-03-31
IE40945B1 (en) 1979-09-12
CH620439A5 (en) 1980-11-28
FR2262984B1 (ja) 1978-07-28
DE2411382C3 (de) 1979-09-06
FR2262984A1 (ja) 1975-10-03
PL93499B1 (ja) 1977-05-30
BG24813A4 (en) 1978-05-12
IL46760A0 (en) 1975-05-22
CH620440A5 (en) 1980-11-28
ATA153875A (de) 1977-11-15
CH622016A5 (en) 1981-03-13
IE40945L (en) 1975-09-09
FI63571C (fi) 1983-07-11
FI750652A (ja) 1975-09-10
ES440350A1 (es) 1977-03-16
CH622015A5 (en) 1981-03-13
DK137188B (da) 1978-01-30
NL7502724A (nl) 1975-09-11
CH622017A5 (en) 1981-03-13
SU588916A3 (ru) 1978-01-15
BG24814A4 (en) 1978-05-12
PH14127A (en) 1981-02-26
ES440349A1 (es) 1977-03-01
ES440347A1 (es) 1977-06-01
BE826440A (fr) 1975-09-08
CH620681A5 (en) 1980-12-15
BG25087A3 (en) 1978-07-12
DE2411382A1 (de) 1975-09-18
RO69617A (ro) 1980-08-15
HU177408B (en) 1981-10-28
NO141800B (no) 1980-02-04
DK137188C (da) 1978-07-03
ES440346A1 (es) 1977-03-01
SU577982A3 (ru) 1977-10-25
AT344332B (de) 1978-07-10
PL93699B1 (ja) 1977-06-30
NO750773L (ja) 1975-09-10
CH612425A5 (en) 1979-07-31
ES440345A1 (es) 1977-03-01
DK92975A (ja) 1975-09-10
NO141800C (no) 1980-06-04
SE421919B (sv) 1982-02-08
GB1496418A (en) 1977-12-30
CH622014A5 (en) 1981-03-13
AU7894275A (en) 1976-09-16
CS188221B2 (en) 1979-02-28
CA1049511A (en) 1979-02-27
DD119236A5 (ja) 1976-04-12

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