AR242953A1 - Procedimiento para preparar nuevos derivados sustituidos de benzamida. - Google Patents

Procedimiento para preparar nuevos derivados sustituidos de benzamida.

Info

Publication number
AR242953A1
AR242953A1 AR87307449A AR30744987A AR242953A1 AR 242953 A1 AR242953 A1 AR 242953A1 AR 87307449 A AR87307449 A AR 87307449A AR 30744987 A AR30744987 A AR 30744987A AR 242953 A1 AR242953 A1 AR 242953A1
Authority
AR
Argentina
Prior art keywords
benzamide
procedure
preparing new
new substitute
substitute derivatives
Prior art date
Application number
AR87307449A
Other languages
English (en)
Spanish (es)
Original Assignee
Dainippon Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dainippon Pharmaceutical Co filed Critical Dainippon Pharmaceutical Co
Application granted granted Critical
Publication of AR242953A1 publication Critical patent/AR242953A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/30—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D267/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D267/02—Seven-membered rings
    • C07D267/08—Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D267/10—Seven-membered rings having the hetero atoms in positions 1 and 4 not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AR87307449A 1986-04-30 1987-04-30 Procedimiento para preparar nuevos derivados sustituidos de benzamida. AR242953A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP10155286 1986-04-30
JP31509086 1986-12-31

Publications (1)

Publication Number Publication Date
AR242953A1 true AR242953A1 (es) 1993-06-30

Family

ID=26442419

Family Applications (1)

Application Number Title Priority Date Filing Date
AR87307449A AR242953A1 (es) 1986-04-30 1987-04-30 Procedimiento para preparar nuevos derivados sustituidos de benzamida.

Country Status (18)

Country Link
US (1) US4870074A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EP (1) EP0243959B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
KR (1) KR870010030A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AR (1) AR242953A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (1) AU592177B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA1291135C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CZ (1) CZ284687B6 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE3781195T2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (1) DK175281B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (1) ES2043617T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FI (1) FI87776C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GR (1) GR3005934T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
HK (1) HK18194A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
HU (1) HU198193B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NZ (1) NZ220120A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PH (1) PH24049A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
SK (1) SK289787A3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
SU (1) SU1597101A3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2640139A1 (fr) * 1988-12-14 1990-06-15 Delagrange Laboratoires Application de benzamides substitues comme gastromoteurs
TW243449B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * 1991-02-15 1995-03-21 Hokuriku Pharmaceutical
US5395832A (en) * 1991-02-15 1995-03-07 Hokuriku Seiyaku Co., Ltd. Benzamide derivatives
US5864039A (en) * 1994-03-30 1999-01-26 Yoshitomi Pharmaceutical Industries, Ltd. Benzoic acid compounds and use thereof as medicaments
EP0774460A1 (en) * 1994-03-30 1997-05-21 Yoshitomi Pharmaceutical Industries, Ltd. Benzoic acid compound and use thereof as medicine
JPH11505815A (ja) * 1995-05-23 1999-05-25 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ （２−モルホリニルメチル）ベンズアミン誘導体
JP2001064177A (ja) * 1999-08-16 2001-03-13 Schering Ag ベンズアミド誘導体を有効成分とする製剤
CA2423251A1 (en) * 2000-09-29 2002-04-04 Glaxo Group Limited Morpholin-acetamide derivatives for the treatment of inflammatory diseases
EP1353918B1 (en) * 2000-11-28 2005-01-12 Smithkline Beecham Plc Morpholine derivatives as antagonists of orexin receptors
JP4829417B2 (ja) * 2001-03-26 2011-12-07 明夫 乾 インスリン抵抗性改善薬
CA2463168A1 (en) * 2001-10-08 2003-04-17 Sun Pharmaceutical Industries Limited An antispasmodic agent spaced drug delivery system
GB0207447D0 (en) * 2002-03-28 2002-05-08 Glaxo Group Ltd Novel compounds
GB0208158D0 (en) * 2002-03-28 2002-05-22 Glaxo Group Ltd Novel compounds
GB0207449D0 (en) * 2002-03-28 2002-05-08 Glaxo Group Ltd Novel compounds
HUP0201980A3 (en) * 2002-06-13 2008-06-30 Richter Gedeon Nyrt Process for preparing a benzamide derivative and intermediates thereof
WO2005055989A1 (ja) * 2003-12-09 2005-06-23 Dainippon Sumitomo Pharma Co., Ltd. 薬物含有粒子および該粒子を含む固形製剤
US8524736B2 (en) 2004-01-07 2013-09-03 Armetheon, Inc. Stereoisomeric compounds and methods for the treatment of gastrointestinal and central nervous system disorders
KR101240464B1 (ko) 2004-01-07 2013-03-08 아메데온, 인코포레이티드 위장 및 중추 신경계 장애를 치료하기 위한 입체이성체적화합물 및 그 치료방법
US8138204B2 (en) * 2004-01-07 2012-03-20 Aryx Therapeutics, Inc. Stereoisomeric compounds and methods for the treatment of gastrointestinal and central nervous system disorders
KR101011848B1 (ko) * 2004-09-08 2011-02-01 미쓰비시 타나베 파마 코퍼레이션 모르폴린 화합물
EP1904481B1 (en) * 2005-06-23 2016-02-17 Array Biopharma, Inc. Process for preparing benzimidazole compounds
AU2006284601B2 (en) * 2005-08-31 2012-12-20 Renexxion, Llc Synthetic methods and intermediates for stereoisomeric compounds useful for the treatment of gastrointestinal and central nervous system disorders
JP2009520820A (ja) * 2005-12-20 2009-05-28 メルク エンド カムパニー インコーポレーテッド ナイアシン受容体アゴニスト、前記化合物を含む組成物及び治療方法
KR100750593B1 (ko) * 2006-03-16 2007-08-20 동우신테크 주식회사 치환된 벤즈아미드 유도체의 제조방법
US20080085915A1 (en) * 2006-06-23 2008-04-10 Cyrus Becker Compounds and methods for the treatment of gastrointestinal and central nervous system disorders
KR20100012031A (ko) 2007-04-19 2010-02-04 콘서트 파마슈티컬즈, 인크. 중수소화된 모르폴리닐 화합물
CN101402633A (zh) * 2007-09-11 2009-04-08 上海恒瑞医药有限公司 苯甲酰胺类衍生物、其制备方法及其在医药上的用途
EP2251005B1 (en) 2008-02-13 2012-10-10 Dainippon Sumitomo Pharma Co., Ltd. Orally disintegrating tablets
TWI423967B (zh) * 2008-02-21 2014-01-21 Dainippon Sumitomo Pharma Co 醯胺衍生物及含有其之醫藥組合物
CN102548542B (zh) 2009-08-11 2013-11-20 大日本住友制药株式会社 含有两种以上粒子的口腔速崩片
WO2011107903A1 (en) 2010-03-04 2011-09-09 Ranbaxy Laboratories Limited Highly pure mosapride citrate dihydrate and processes for its preparation
BR112013019942B1 (pt) 2011-02-25 2022-01-11 Yuhan Corporation Uso de composto ou de seu sal farmaceuticamente aceitável, composição farmacêutica, compostos ou seus sais farmaceuticamente aceitáveis e respectivos processos de preparação
KR101657616B1 (ko) 2013-05-24 2016-09-19 주식회사유한양행 피리미딘 고리를 포함하는 바이사이클릭 유도체 및 그의 제조방법
TWI794171B (zh) 2016-05-11 2023-03-01 美商滬亞生物國際有限公司 Ｈｄａｃ抑制劑與ｐｄ-ｌ１抑制劑之組合治療
TWI808055B (zh) 2016-05-11 2023-07-11 美商滬亞生物國際有限公司 Hdac 抑制劑與 pd-1 抑制劑之組合治療
CN111349052B (zh) * 2020-04-07 2021-02-12 福建海西新药创制有限公司 一种枸橼酸莫沙必利的合成方法
CN114560822B (zh) * 2020-11-27 2024-05-28 鲁南制药集团股份有限公司 一种莫沙必利的二羧酸晶体
CN114591260B (zh) * 2020-12-05 2025-07-11 鲁南制药集团股份有限公司 一种莫沙必利有机酸盐
CN119241463A (zh) * 2024-10-22 2025-01-03 吉林修正药业新药开发有限公司 一种枸橼酸莫沙必利杂质化合物及其制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH451142A (de) * 1965-01-19 1968-05-15 Sandoz Ag Verfahren zur Herstellung neuer basisch substituierter Benzoesäureamide
US4029786A (en) * 1972-08-11 1977-06-14 Imperial Chemical Industries Limited Morpholine derivatives for treating depression
US4323503A (en) * 1976-08-04 1982-04-06 Societe D'etudes Scientifiques Et Industrielles De L'ile-De-France Substituted 2,3-alkylene di (oxy) benzamides and derivatives
US4210754A (en) * 1977-02-01 1980-07-01 Hoffmann-La Roche Inc. Morpholino containing benzamides
US4692445A (en) * 1983-04-29 1987-09-08 Rorer Pharmaceutical Corporation Bicyclic benzenoid aminoalkylene ethers and thioethers, pharmaceutical compositions and use
FR2575158B1 (fr) * 1984-12-20 1987-10-02 Pf Medicament Arylalcoyloxymethyl-2 morpholines, leur preparation et leur application en tant que medicaments utiles dans le traitement des troubles du systeme nerveux central
JPH0390274A (ja) * 1989-08-28 1991-04-16 Furukawa Alum Co Ltd Ａｌ又はＡｌ合金の気相ろう付法

Also Published As

Publication number Publication date
DK175281B1 (da) 2004-08-09
FI871828A0 (fi) 1987-04-27
FI87776C (fi) 1993-02-25
CZ289787A3 (cs) 1998-11-11
EP0243959B1 (en) 1992-08-19
HK18194A (en) 1994-03-11
SK279058B6 (sk) 1998-06-03
FI87776B (fi) 1992-11-13
PH24049A (en) 1990-03-05
EP0243959A1 (en) 1987-11-04
SK289787A3 (en) 1998-06-03
CA1291135C (en) 1991-10-22
AU592177B2 (en) 1990-01-04
DK218787D0 (da) 1987-04-29
SU1597101A3 (ru) 1990-09-30
NZ220120A (en) 1989-06-28
GR3005934T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1993-06-07
HUT45514A (en) 1988-07-28
CZ284687B6 (cs) 1999-02-17
ES2043617T3 (es) 1994-01-01
DK218787A (da) 1987-10-31
DE3781195T2 (de) 1993-02-18
FI871828A7 (fi) 1987-10-31
US4870074A (en) 1989-09-26
HU198193B (en) 1989-08-28
DE3781195D1 (de) 1992-09-24
AU7227587A (en) 1987-11-05
KR870010030A (ko) 1987-11-30

Similar Documents

Publication Publication Date Title
AR242953A1 (es) Procedimiento para preparar nuevos derivados sustituidos de benzamida.
HU906232D0 (en) Process for the preparation of pyridile derivatives
PT84938A (en) Process for the preparation of imidazoquinolinylether derivatives
AR243491A1 (es) Procedimiento para preparar derivados de catecol farmacologicamente activos.
PL250524A1 (en) Process for preparing derivatives of 2,2'-imino-bisethanol
PT86309A (en) Process for the preparation of substituted basic 2-aminotetralins
PT84831A (en) Process for the preparation of new pyrazol-3-amines
GR870220B (en) Process for the preparation of dichloroaniline derivatives
ES2017956B3 (es) Procedimiento para preparar derivados de 4-acetoxi-3-hidroxietilazetidin-2-ona.
CS479187A2 (en) Process for preparing derivatives of 2-brom-alpha-ergo-cryptine
AR242585A1 (es) Procedimiento para la produccion de polideoxi-ribonucleotido defibrotide
KR950010075B1 (en) Process for the preparation of 1,2,3,6-tetrahydro-5-nitro-pyrimidine derivatives
PL256373A1 (en) Process for preparing silibinin,free of isosilibin
MX161397A (es) Procedimiento para preparar derivados de 1,3 oxazolidin-2-ona
AR242199A1 (es) Procedimiento para la preparacion de nuevos derivados de alquilen-diamina
ES530574A0 (es) Procedimiento para preparar derivados de pirazol 1,5-a-piridina
EP0255904A3 (en) Process for the preparation of dihydrocyclocitral
PT86176A (en) Process for the preparation of 12-halogenated forskolin derivatives
AR242797A1 (es) Procedimiento para la preparacion de derivados de acido 16,17-acetal substituido pregnano-21-oico.
PT83884A (en) Process for the preparation of 1 azolyl-3,3-dimethyl-tutan-2-on-and-ol derivatives
EP0264089A3 (en) Process for the preparation of sulphatobetaines
ES546802A0 (es) Procedimiento para preparar derivados de 7-oxo-4-tia-1-aza- biciclo(3,2,0)hept-2-eno
PT84100A (en) Process for the preparation of fluorinated diaminoalkyne derivatives
PL266478A1 (en) Procedure for the production of mercaptoacyloproline
EP0240741A3 (en) Process for the preparation of inulase