AR230183A1 - Procedimiento para la preparacion de medicamentos con un alto grado de solubilidad y/o disolucion - Google Patents

Procedimiento para la preparacion de medicamentos con un alto grado de solubilidad y/o disolucion

Info

Publication number
AR230183A1
AR230183A1 AR291268A AR29126882A AR230183A1 AR 230183 A1 AR230183 A1 AR 230183A1 AR 291268 A AR291268 A AR 291268A AR 29126882 A AR29126882 A AR 29126882A AR 230183 A1 AR230183 A1 AR 230183A1
Authority
AR
Argentina
Prior art keywords
medicines
dissolution
solubility
procedure
preparation
Prior art date
Application number
AR291268A
Other languages
English (en)
Spanish (es)
Original Assignee
Elan Corp Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Elan Corp Ltd filed Critical Elan Corp Ltd
Application granted granted Critical
Publication of AR230183A1 publication Critical patent/AR230183A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Cephalosporin Compounds (AREA)
  • Saccharide Compounds (AREA)
AR291268A 1982-04-19 1982-11-11 Procedimiento para la preparacion de medicamentos con un alto grado de solubilidad y/o disolucion AR230183A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8206646A FR2525108B1 (fr) 1982-04-19 1982-04-19 Medicaments a haut degre de solubilite et procede pour leur obtention

Publications (1)

Publication Number Publication Date
AR230183A1 true AR230183A1 (es) 1984-03-01

Family

ID=9273120

Family Applications (1)

Application Number Title Priority Date Filing Date
AR291268A AR230183A1 (es) 1982-04-19 1982-11-11 Procedimiento para la preparacion de medicamentos con un alto grado de solubilidad y/o disolucion

Country Status (18)

Country Link
US (2) US4610875A (pm)
JP (1) JPS58183615A (pm)
AR (1) AR230183A1 (pm)
AT (1) AT389813B (pm)
AU (1) AU555579B2 (pm)
BE (1) BE894942A (pm)
CA (1) CA1225029A (pm)
CH (1) CH655003A5 (pm)
DE (1) DE3241097A1 (pm)
ES (1) ES517444A0 (pm)
FR (1) FR2525108B1 (pm)
GB (1) GB2119784B (pm)
IE (1) IE54084B1 (pm)
IT (1) IT1153099B (pm)
LU (1) LU84468A1 (pm)
NL (1) NL8204461A (pm)
PT (1) PT75867B (pm)
SE (1) SE8206697L (pm)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2525108B1 (fr) * 1982-04-19 1989-05-12 Elan Corp Ltd Medicaments a haut degre de solubilite et procede pour leur obtention
JPS60139688A (ja) * 1983-12-28 1985-07-24 Tokyo Tanabe Co Ltd 無定形ジヒドロピリジン粉末製剤
EP0214092A1 (en) * 1985-08-08 1987-03-11 Ciba-Geigy Ag Enhanced absorption of psychoactive 2-aryl-pyrazolo quinolines as a solid molecular dispersion in polyvinylpyrrolidone
US4798725A (en) * 1986-06-16 1989-01-17 Norwich Eaton Pharmaceuticals, Inc. Sustained release capsule
US4772473A (en) * 1986-06-16 1988-09-20 Norwich Eaton Pharmaceuticals, Inc. Nitrofurantoin dosage form
US4832953A (en) * 1987-08-13 1989-05-23 Alza Corporation Method for preventing the formation of a crystalline hydrate in a dispersion of a liquid in a monaqueous matrix
JPH05501563A (ja) * 1989-11-18 1993-03-25 シエーリング・アグロケミカルズ・リミテツド プロペン酸誘導体の製造
IT1242642B (it) * 1990-04-17 1994-05-16 Alfa Wassermann Spa Formulazioni iniettabili contenenti naproxen sale sodico.
JPH0648937A (ja) * 1992-04-07 1994-02-22 Seitai Kagaku Kenkyusho:Kk 経口投与に適する薬剤およびその製造方法
US5512300A (en) * 1992-09-15 1996-04-30 Warner-Lambert Company Prevention of ibuprofen from forming low melting eutectics with other therapeutic agents in solid dosage forms
FR2722984B1 (fr) * 1994-07-26 1996-10-18 Effik Lab Procede de preparation de formes pharmaceutiques seches et les compositions pharmaceutiques ainsi realisees
US5994348A (en) 1995-06-07 1999-11-30 Sanofi Pharmaceutical compositions containing irbesartan
FR2736550B1 (fr) * 1995-07-14 1998-07-24 Sandoz Sa Composition pharmaceutique sous la forme d'une dispersion solide comprenant un macrolide et un vehicule
US5686133A (en) * 1996-01-31 1997-11-11 Port Systems, L.L.C. Water soluble pharmaceutical coating and method for producing coated pharmaceuticals
WO1997034601A1 (fr) * 1996-03-18 1997-09-25 Eisai Co., Ltd. Compositions medicamenteuses a solubilite amelioree
US6066339A (en) * 1997-10-17 2000-05-23 Elan Corporation, Plc Oral morphine multiparticulate formulation
US6086915A (en) * 1998-04-01 2000-07-11 Bioresponse L.L.C. Compositions and methods of adjusting steroid hormone metabolism through phytochemicals
CN1198591C (zh) * 1998-07-20 2005-04-27 史密丝克莱恩比彻姆公司 在口服固体剂型中包含依普沙坦的生物利用度提高的制剂
EP1120120A4 (en) * 1998-10-05 2009-04-29 Eisai R&D Man Co Ltd TABLETS DISSOLVING DIRECTLY IN MOUTH
JP5767429B2 (ja) * 1999-11-12 2015-08-19 アッヴィ・インコーポレイテッド 固体分散剤中の結晶化阻害剤
US7364752B1 (en) 1999-11-12 2008-04-29 Abbott Laboratories Solid dispersion pharamaceutical formulations
CN1376146B (zh) * 1999-12-08 2011-04-06 法马西亚公司 提高了生物利用率的雪列柯西的固态形式
SK8562002A3 (en) 1999-12-23 2003-10-07 Pfizer Prod Inc Pharmaceutical compositions providing enhanced drug concentrations
IL134701A0 (en) * 2000-02-23 2001-04-30 J P M E D Ltd Homogeneous solid matrix containing vegetable proteins
DE10026698A1 (de) * 2000-05-30 2001-12-06 Basf Ag Selbstemulgierende Wirkstoffformulierung und Verwendung dieser Formulierung
WO2001095912A1 (fr) 2000-06-16 2001-12-20 Mitsubishi Pharma Corporation Compositions permettant de reguler la plage et/ou la vitesse de liberation du ph
BR0114896A (pt) * 2000-10-24 2003-08-12 Ajinomoto Kk Preparação contendo nateglinida, e, método para produzir a mesma
SK15742003A3 (sk) * 2001-06-22 2005-01-03 Pfizer Products Inc. Farmaceutická kompozícia zahrnujúca adsorbát amorfného liečiva
EP1269994A3 (en) * 2001-06-22 2003-02-12 Pfizer Products Inc. Pharmaceutical compositions comprising drug and concentration-enhancing polymers
EP1401399A2 (en) * 2001-06-22 2004-03-31 Pfizer Products Inc. Pharmaceutical compositions containing polymer and drug assemblies
SI21223A (sl) * 2002-06-19 2003-12-31 Krka, Tovarna Zdravil, D.D., Novo Mesto Farmacevtska formulacija s stabiliziranim amorfnim donepezilijevim kloridom
US20040132771A1 (en) * 2002-12-20 2004-07-08 Pfizer Inc Compositions of choleseteryl ester transfer protein inhibitors and HMG-CoA reductase inhibitors
US20050152932A1 (en) * 2003-06-12 2005-07-14 Valery Normand Non-crystalline perfume or flavor delivery system
US8377952B2 (en) 2003-08-28 2013-02-19 Abbott Laboratories Solid pharmaceutical dosage formulation
US8025899B2 (en) 2003-08-28 2011-09-27 Abbott Laboratories Solid pharmaceutical dosage form
US20050048112A1 (en) 2003-08-28 2005-03-03 Jorg Breitenbach Solid pharmaceutical dosage form
EP1827429A4 (en) * 2004-12-20 2009-08-05 Reddys Lab Ltd Dr PHARMACEUTICAL COMPOSITIONS COMPRISING AMORPHOUS BENZIMIDAZOLE COMPOUNDS
ES2384333T3 (es) * 2005-04-11 2012-07-03 Abbott Laboratories Composiciones farmacéuticas que tienen perfiles de disolución mejorados para fármacos poco solubles
WO2006119779A2 (en) * 2005-05-10 2006-11-16 Lifecycle Pharma A/S A pharmaceutical composition comprising an aldosterone antagonist in form of solid solution
CA2640165A1 (en) * 2006-01-27 2007-08-02 The Provost, Fellows And Scholars Of The College Of The Holy And Undivid Ed Trinity Of Queen Elizabeth Near Dublin A method of producing porous microparticles
PT103743B (pt) * 2007-05-16 2013-01-15 Hovione Farmaciencia S A Processo para preparar derivados de 21-disódio fosfato de pregnanos.
WO2010052450A1 (en) * 2008-11-04 2010-05-14 Cipla Limited Tiotropium bromide having a low degree of crystallinity
EP2654731B1 (en) * 2010-12-23 2016-07-27 AbbVie Deutschland GmbH & Co. KG Solid retard formulations based on solid dispersions
WO2012164575A2 (en) 2011-05-27 2012-12-06 Hetero Research Foundation Amorphous ritonavir co-precipitated

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4151273A (en) * 1974-10-31 1979-04-24 The Regents Of The University Of California Increasing the absorption rate of insoluble drugs
JPS5163925A (ja) * 1974-11-30 1976-06-02 Kyowa Hakko Kogyo Kk Muteikeikuroramufuenikooruno seizoho
US4127647A (en) * 1975-04-08 1978-11-28 Meiji Seika Kaisha, Ltd. Process for preparation of stable amorphous macrolide antibiotic solids
JPS51118816A (en) * 1975-04-08 1976-10-19 Meiji Seika Kaisha Ltd A process for stabilizing non-crystalloidal solid
DE2634004B2 (de) * 1976-07-29 1978-08-10 Bernhard Dr. 8000 Muenchen Lippold Verfahren zur Beschleunigung der Auflösung und Verbesserung der Löslichkeit von schlechtlöslichen zur peroralen Verabreichung bestimmten Arzneistoffen
GB1579818A (en) * 1977-06-07 1980-11-26 Yamanouchi Pharma Co Ltd Nifedipine-containing solid preparation composition
EP0001247A1 (en) * 1977-09-14 1979-04-04 Kanebo, Ltd. Pharmaceutical preparation containing nifedipine and a method for producing the same.
US4128632A (en) * 1978-02-13 1978-12-05 Merck & Co., Inc. Solubilization of Rafoxanide
US4344934A (en) * 1978-11-20 1982-08-17 American Home Products Corporation Therapeutic compositions with enhanced bioavailability
JPS6024768B2 (ja) * 1979-06-16 1985-06-14 フロイント産業株式会社 活性化薬剤の製法
DE3013839A1 (de) * 1979-04-13 1980-10-30 Freunt Ind Co Ltd Verfahren zur herstellung einer aktivierten pharmazeutischen zusammensetzung
JPS587609B2 (ja) * 1979-06-17 1983-02-10 フロイント産業株式会社 粉体薬剤のコ−テング法
JPS55139319A (en) * 1979-04-13 1980-10-31 Furointo Sangyo Kk Activation of drug soluble in alkali and acid
JPS5948810B2 (ja) * 1980-03-22 1984-11-29 山之内製薬株式会社 ニカルジピン持続性製剤用組成物
CA1146866A (en) * 1979-07-05 1983-05-24 Yamanouchi Pharmaceutical Co. Ltd. Process for the production of sustained release pharmaceutical composition of solid medical material
JPS5646837A (en) * 1979-09-27 1981-04-28 Kowa Yakuhin Kogyo Kk Preparation of ibuprofen clathrate compound
JPS5655370A (en) * 1979-10-13 1981-05-15 Kyorin Pharmaceut Co Ltd Amorphous nicomol
US4327080A (en) * 1981-07-13 1982-04-27 E. R. Squibb & Sons, Inc. Novel Bendroflumethiazide formulations and method
FR2525108B1 (fr) * 1982-04-19 1989-05-12 Elan Corp Ltd Medicaments a haut degre de solubilite et procede pour leur obtention
DE3318649A1 (de) * 1983-05-21 1984-11-22 Bayer Ag, 5090 Leverkusen Zweiphasenformulierung

Also Published As

Publication number Publication date
IT8224368A1 (it) 1984-05-23
JPH0341444B2 (pm) 1991-06-24
US4769236A (en) 1988-09-06
FR2525108A1 (fr) 1983-10-21
ATA427282A (de) 1989-07-15
AT389813B (de) 1990-02-12
IT8224368A0 (it) 1982-11-23
IE54084B1 (en) 1989-06-07
ES8505249A1 (es) 1985-05-16
SE8206697L (sv) 1983-10-20
PT75867A (fr) 1982-12-01
CH655003A5 (fr) 1986-03-27
GB2119784A (en) 1983-11-23
AU555579B2 (en) 1986-10-02
FR2525108B1 (fr) 1989-05-12
JPS58183615A (ja) 1983-10-26
IE822610L (en) 1983-10-19
SE8206697D0 (sv) 1982-11-24
BE894942A (fr) 1983-05-09
DE3241097A1 (de) 1983-10-20
AU9043182A (en) 1983-10-27
IT1153099B (it) 1987-01-14
LU84468A1 (fr) 1983-06-13
ES517444A0 (es) 1985-05-16
PT75867B (fr) 1986-01-21
DE3241097C2 (pm) 1989-04-13
CA1225029A (en) 1987-08-04
NL8204461A (nl) 1983-11-16
GB2119784B (en) 1986-04-03
US4610875A (en) 1986-09-09

Similar Documents

Publication Publication Date Title
AR230183A1 (es) Procedimiento para la preparacion de medicamentos con un alto grado de solubilidad y/o disolucion
DK68392D0 (da) Farmaceutisk praeparat indeholdende cefuroximaxetil
ES524892A0 (es) Un procedimiento para la preparacion de una tableta farmaceutica
ES530593A0 (es) Un procedimiento para la preparacion de nuevos derivados de daunorrubicina y doxorrubicina
ES555840A0 (es) Un procedimiento para la desproteccion de esteres y eteres alilicos
ES521864A0 (es) Un procedimiento para la preparacion de derivados de areno y hetero-arenocarboxamidas
IT1183060B (it) Procedimento di preparazione. cefem composti ad azione farmaceutica e relativo
AR231279A1 (es) Un procedimiento para la preparacion de 2-2-benoil-3-mercaptopropionil amino-4-metiltio-butanoles quirales y acidos 2-2-bencil-3-metilmercaptopropionilamino-4-metil-tiobutiricos quirales
NO822671L (no) Farmasoeytisk virksomme forbindelser og fremgangsmaate for deres fremstilling.
ES553868A0 (es) Un procedimiento para la preparacion de epidofilotaxina y compuestos relacionados.
FI831687L (fi) Farmaceutiska blandningar vilka innehaoller flere aktiva bestaondsdelar
MX7829A (es) Quinazolindionas y piridopirimindionas y procedimiento para su preparacion
DK128485D0 (da) Farmaceutisk praeparat indeholdende tetracyclin- eller doxycyclinsalte og en fremgangsmaade til fremstilling af et saadant praeparat
MX7639E (es) Procedimiento biotecnologico para la preparacion de tirosina
MX162953B (es) Articulo fotosensible y procedimiento para su preparacion
ES545233A0 (es) Un procedimiento para la preparacion de tiazol y tiazin-ben-cimidazoles
AR227962A1 (es) Procedimiento para preparar antibioticos ll-bo1208alpha y ll-bo1208beta
IT8067127A0 (it) Supposta farmaceutica e procedimento per la sua preparazione
IT1152106B (it) Preparato farmaceutico vasodilatatore
ES506854A0 (es) Mejoras en un procedimiento para la preparacion de penici- linas y derivados de penicilinas.
ES511366A0 (es) "un procedimiento para la preparacion de derivados de piridina y pirrolidina".
NL185666C (nl) Farmaceutisch preparaat of voorwerp en geneeskrachtige verbindingen.
ES539247A0 (es) Un procedimiento para la preparacion de benzotienil-, benzofuranil o naftil-derivados
ES518257A0 (es) Un procedimiento para la preparacion de derivados de tetrahidronaftaleno y de indano.
IT1178277B (it) Formulazioni farmaceutiche e veterinarie e procedimento preparazione