AR225773A1 - Procedimiento para la preparacion de bis-(hidroxi-alcohilamidas)de acidos 5-(n-alcohil-alfa-hidroxiacil-amino)-2,4,6-triyodo-isoftalicos - Google Patents

Procedimiento para la preparacion de bis-(hidroxi-alcohilamidas)de acidos 5-(n-alcohil-alfa-hidroxiacil-amino)-2,4,6-triyodo-isoftalicos

Info

Publication number
AR225773A1
AR225773A1 AR282095A AR28209580A AR225773A1 AR 225773 A1 AR225773 A1 AR 225773A1 AR 282095 A AR282095 A AR 282095A AR 28209580 A AR28209580 A AR 28209580A AR 225773 A1 AR225773 A1 AR 225773A1
Authority
AR
Argentina
Prior art keywords
triyodo
isoftalicos
hidroxiacil
alcohilamidas
alcohil
Prior art date
Application number
AR282095A
Other languages
English (en)
Spanish (es)
Original Assignee
Bracco Ind Chimica Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bracco Ind Chimica Spa filed Critical Bracco Ind Chimica Spa
Application granted granted Critical
Publication of AR225773A1 publication Critical patent/AR225773A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/28—Radicals substituted by nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Polyamides (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AR282095A 1979-08-09 1980-08-08 Procedimiento para la preparacion de bis-(hidroxi-alcohilamidas)de acidos 5-(n-alcohil-alfa-hidroxiacil-amino)-2,4,6-triyodo-isoftalicos AR225773A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT25026/79A IT1193211B (it) 1979-08-09 1979-08-09 Derivati dell'acido 2,4,6-triiodo-isoftalico,metodo per la loro preparazione e mezzi di contrasto che li contengono

Publications (1)

Publication Number Publication Date
AR225773A1 true AR225773A1 (es) 1982-04-30

Family

ID=11215461

Family Applications (2)

Application Number Title Priority Date Filing Date
AR282095A AR225773A1 (es) 1979-08-09 1980-08-08 Procedimiento para la preparacion de bis-(hidroxi-alcohilamidas)de acidos 5-(n-alcohil-alfa-hidroxiacil-amino)-2,4,6-triyodo-isoftalicos
AR286853A AR225836A1 (es) 1979-08-09 1981-09-23 Procedimiento para la preparacion de bis-(hidroxialcohilamidas)de acidos(5-(n-alcohil-a-hidroxiacil-amino)-2,4,6-triyodo-isoftalico

Family Applications After (1)

Application Number Title Priority Date Filing Date
AR286853A AR225836A1 (es) 1979-08-09 1981-09-23 Procedimiento para la preparacion de bis-(hidroxialcohilamidas)de acidos(5-(n-alcohil-a-hidroxiacil-amino)-2,4,6-triyodo-isoftalico

Country Status (19)

Country Link
US (1) US4352788A (da)
EP (1) EP0026281B1 (da)
JP (1) JPS5827264B2 (da)
AR (2) AR225773A1 (da)
AT (1) ATE1995T1 (da)
AU (1) AU541428B2 (da)
CA (1) CA1128065A (da)
DE (1) DE3061347D1 (da)
DK (1) DK158659C (da)
ES (1) ES494076A0 (da)
FI (1) FI71124C (da)
IE (1) IE50149B1 (da)
IT (1) IT1193211B (da)
MX (1) MX9202639A (da)
NL (1) NL940024I2 (da)
NO (1) NO150154C (da)
PL (2) PL123167B1 (da)
PT (1) PT71682B (da)
YU (1) YU42352B (da)

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DE3150917A1 (de) * 1981-12-18 1983-06-30 Schering Ag, 1000 Berlin Und 4619 Bergkamen "2-amino-1-(1,3-dioxolan-4-yl)-ethanol-verbindungen, deren herstellung und verwendung zur weiterverarbeitung"
DE3150916A1 (de) * 1981-12-18 1983-06-30 Schering Ag, 1000 Berlin Und 4619 Bergkamen N-hydroxyaethylierte 2,4,6-trijodaminoisiophthalsaeure-bis- trihydroxybutylamide, deren herstellung und diese enthaltende roentgenkontrastmittel"
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US4584401A (en) * 1983-10-20 1986-04-22 Biophysica Foundation Methods and compositions involving polyhydroxylated polyiodo non-ionic contrast media
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EP0233249B1 (en) * 1985-08-09 1993-11-24 Cook Imaging Corporation Non-ionic polyol contrast media from ionic contrast media
KR960016747B1 (ko) * 1987-05-22 1996-12-20 브라코 인터내셔날 비. 브이 5-아실아미노-2,4,6-트리요오도-또는 트리브로모-벤조산 유도체의 제조 방법
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US5614638A (en) * 1989-11-29 1997-03-25 Bracco International B.V. Nonionic radiographic contrast agents
US5869024A (en) * 1989-11-29 1999-02-09 Bracco International B.V. Methods and compositions for using non-ionic contrast agents to reduce the risk of clot formation in diagnostic procedures
US5075502A (en) * 1989-12-13 1991-12-24 Mallinckrodt, Inc. Nonionic x-ray contrast agents, compositions and methods
US5019371A (en) * 1990-11-21 1991-05-28 Mallinckrodt Medical, Inc. Novel x-ray contrast agents, compositions and methods
US5527926A (en) * 1990-11-26 1996-06-18 Bracco International B.V. Methods and compositions for using non-ionic contrast agents to reduce the risk of clot formation in diagnostic procedures
IT1248741B (it) * 1991-02-26 1995-01-26 Bracco Spa Processo di concentrazione e di purificazione di composti organici
US5356613A (en) * 1991-03-18 1994-10-18 Mallinckrodt Medical, Inc. X-ray contrast agents, compositions and methods
US5278311A (en) * 1992-06-05 1994-01-11 E. R. Squibb & Sons, Inc. Nonionic radiographic contrast agents
IL110391A (en) * 1993-07-30 1998-12-06 Zambon Spa Process for the formation of infamidol
IT1274027B (it) * 1994-03-03 1997-07-14 Zambon Spa Processo per la preparazione e purificazione di mezzi di contrasto iodurati
US6310243B1 (en) * 1994-09-23 2001-10-30 Nycomed Imaging As Iodinated x-ray contrast media
IT1271107B (it) * 1994-11-29 1997-05-26 Zambon Spa Processo per la preparazione di un intermedio utile nella sintesi di composti organici
DE19510864A1 (de) * 1995-03-16 1996-09-19 Schering Ag Röntgenkontrastmittel für die Computertomographie und Urographie
IT1275429B (it) * 1995-05-18 1997-08-07 Zambon Spa Processo per la preparazione di un intermedio utile nella sintesi di composti organici
ATE176663T1 (de) * 1995-05-23 1999-02-15 Fructamine Spa Verfahren zur herstellung von dicarbonsäurechlorid
IT1288114B1 (it) * 1996-06-13 1998-09-10 Fructamine Spa Processo per la purificazione di un intermedio
IT1292127B1 (it) * 1997-06-11 1999-01-25 Bracco Spa Processo per la dissalazione di sostanze instabili a ph acidi
US6723746B2 (en) * 1998-09-08 2004-04-20 Veritas Pharmaceuticals, Inc. Functional radiographic imaging methods and agents
US20010038682A1 (en) * 1998-09-08 2001-11-08 Jesse Salb Radiographic assessment of tissue response to compounds
US6226352B1 (en) * 1998-09-08 2001-05-01 Veritas Pharmaceuticals, Inc. System and method for radiographic imaging of tissue
US6751290B2 (en) 1998-09-08 2004-06-15 Veritas Pharmaceuticals, Inc. Radiographic assessment of tissue after exposure to a compound
US20040170561A1 (en) * 1998-09-08 2004-09-02 Jesse Salb Functional radiographic imaging methods and agents
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US6660248B2 (en) 2000-11-10 2003-12-09 William Marsh Rice University Fullerene (C60)-based X-ray contrast agent for diagnostic imaging
IT1319671B1 (it) * 2000-12-01 2003-10-23 Bracco Spa Processo per la preparazione di (s)-n,n'-bis(2-idrossi-1-(idrossimetil)etil)-5-((2-idrossi-1-ossopropil)ammino)
SI1836239T1 (sl) 2005-01-13 2009-04-30 Cinv Ag Kompozitni materiali, ki vsebujejo ogljikove nanodelce
WO2008087214A1 (en) * 2007-01-19 2008-07-24 Cinvention Ag Porous, non-degradable implant made by powder molding
US20080213742A1 (en) * 2007-02-28 2008-09-04 Cinvention Ag High surface cultivation system
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WO2008104599A1 (en) * 2007-02-28 2008-09-04 Cinvention Ag High surface cultivation system bag
DE102007058220A1 (de) 2007-12-03 2009-06-04 Bayer Schering Pharma Aktiengesellschaft Dimere macrocyclisch substituierte Benzolderivate
EP2385845A1 (en) 2009-01-09 2011-11-16 Ge Healthcare As Contrast media compositions
EP2243767A1 (en) 2009-04-21 2010-10-27 Bracco Imaging S.p.A Process for the iodination of aromatic compounds
WO2012136813A2 (en) 2011-04-07 2012-10-11 Universitetet I Oslo Agents for medical radar diagnosis
CN102363600B (zh) * 2011-10-24 2013-07-17 江苏省原子医学研究所 一种碘美普尔的制备方法
US10067231B2 (en) 2012-10-05 2018-09-04 Faro Technologies, Inc. Registration calculation of three-dimensional scanner data performed between scans based on measurements by two-dimensional scanner
DE102012109481A1 (de) 2012-10-05 2014-04-10 Faro Technologies, Inc. Vorrichtung zum optischen Abtasten und Vermessen einer Umgebung
PT108524B (pt) 2015-06-02 2017-12-15 Hovione Farmaciência S A Processo para a preparação de intermediários úteis na preparação de agentes de contraste não-iónicos
CN106316878B (zh) * 2015-06-15 2018-01-19 重庆常捷医药有限公司 一种碘美普尔杂质的制备方法
CN110023279B (zh) 2016-12-05 2022-03-11 伯拉考成像股份公司 放射照相剂中间体的机械化学合成
CN107253918A (zh) * 2017-07-27 2017-10-17 成都丽璟科技有限公司 一种制备碘美普尔的新方法
KR102128423B1 (ko) * 2018-09-17 2020-07-01 (주)유케이케미팜 조영제 이오메프롤의 제조방법
CN118414325A (zh) 2021-12-20 2024-07-30 伯拉考成像股份公司 制备2,4,6-三碘间苯二甲酸双酰胺的方法
CN116354842A (zh) * 2021-12-20 2023-06-30 重庆圣华曦药业股份有限公司 一种改进的碘美普尔制备方法及其在制剂中的应用

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SE344166B (da) * 1966-12-13 1972-04-04 Pharmacia Ab
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US3701771A (en) * 1969-06-27 1972-10-31 Nyegaard & Co As N-(2,4,6-triiodobenzoyl)-sugar amines
US3886859A (en) * 1974-04-26 1975-06-03 Gen Electric Compactor brake
CH616403A5 (en) * 1975-10-29 1980-03-31 Bracco Ind Chimica Spa Process for the preparation of 2,4,6-triodoisophthalamides which are readily soluble in water.
GB1548594A (en) * 1976-06-11 1979-07-18 Nyegaard & Co As Triiodoisophthalic acid amides
DE2628517C2 (de) * 1976-06-23 1985-02-21 Schering AG, 1000 Berlin und 4709 Bergkamen Dicarbonsäure-bis(3,5-dicarbamoyl-2,4,6-trijodanilid)-Verbindungen, Verfahren zu ihrer Herstellung und Röntgenkontrastmittel
DE2909439A1 (de) * 1979-03-08 1980-09-18 Schering Ag Neue nichtionische roentgenkontrastmittel

Also Published As

Publication number Publication date
NO150154B (no) 1984-05-21
AR225836A1 (es) 1982-04-30
IT1193211B (it) 1988-06-15
PL226143A1 (da) 1981-05-08
YU42352B (en) 1988-08-31
FI71124C (fi) 1986-11-24
IT7925026A0 (it) 1979-08-09
CA1128065A (en) 1982-07-20
NO150154C (no) 1984-08-29
MX9202639A (es) 1992-06-30
DK158659C (da) 1991-01-21
ES8106696A1 (es) 1981-09-01
IE50149B1 (en) 1986-02-19
PL123167B1 (en) 1982-09-30
JPS5827264B2 (ja) 1983-06-08
DK158659B (da) 1990-07-02
ES494076A0 (es) 1981-09-01
NO802373L (no) 1981-02-10
PT71682A (en) 1980-09-01
FI802373A (fi) 1981-02-10
PT71682B (en) 1981-06-15
AU6061680A (en) 1981-02-12
YU201180A (en) 1983-02-28
NL940024I1 (nl) 1995-01-16
DK343980A (da) 1981-02-10
NL940024I2 (nl) 1999-06-01
JPS5629553A (en) 1981-03-24
ATE1995T1 (de) 1982-12-15
EP0026281A1 (de) 1981-04-08
AU541428B2 (en) 1985-01-10
DE3061347D1 (en) 1983-01-20
IE801684L (en) 1981-02-09
EP0026281B1 (de) 1982-12-15
FI71124B (fi) 1986-08-14
PL126118B1 (en) 1983-07-30
US4352788A (en) 1982-10-05

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