IT1271107B - Processo per la preparazione di un intermedio utile nella sintesi di composti organici - Google Patents

Processo per la preparazione di un intermedio utile nella sintesi di composti organici

Info

Publication number
IT1271107B
IT1271107B ITMI942412A ITMI942412A IT1271107B IT 1271107 B IT1271107 B IT 1271107B IT MI942412 A ITMI942412 A IT MI942412A IT MI942412 A ITMI942412 A IT MI942412A IT 1271107 B IT1271107 B IT 1271107B
Authority
IT
Italy
Prior art keywords
preparation
amino
synthesis
organic compounds
triiodoisophthalic
Prior art date
Application number
ITMI942412A
Other languages
English (en)
Inventor
Vincenzo Cannata
Corrado Velgi
Giuseppe Barreca
Original Assignee
Zambon Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zambon Spa filed Critical Zambon Spa
Publication of ITMI942412A0 publication Critical patent/ITMI942412A0/it
Priority to ITMI942412A priority Critical patent/IT1271107B/it
Priority to AT95939294T priority patent/ATE178585T1/de
Priority to PCT/EP1995/004635 priority patent/WO1996016927A1/en
Priority to US08/836,984 priority patent/US5856570A/en
Priority to JP51816096A priority patent/JP3795524B2/ja
Priority to ES95939294T priority patent/ES2129877T3/es
Priority to EP95939294A priority patent/EP0794937B1/en
Priority to CZ19971637A priority patent/CZ288587B6/cs
Priority to DE69508959T priority patent/DE69508959T2/de
Priority to IL11616695A priority patent/IL116166A/xx
Priority to ZA9510152A priority patent/ZA9510152B/xx
Publication of ITMI942412A1 publication Critical patent/ITMI942412A1/it
Application granted granted Critical
Publication of IT1271107B publication Critical patent/IT1271107B/it
Priority to FI972261A priority patent/FI972261A/fi
Priority to NO972428A priority patent/NO308212B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
    • C07C227/18—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions involving amino or carboxyl groups, e.g. hydrolysis of esters or amides, by formation of halides, salts or esters

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Viene descritto un processo per la preparazione del dicloruro dell'acido 5-ammino-2, 4, 6-triiodoisoftalico per clorurazione dell'acido 5-amino-2, 4, 6-triiodoisoftalico con cloruro di tionile in presenza di un adatto solvente e di un sale di un'ammina terziaria o di un ammonio quaternario in rapporto molare compreso tra 1:1 ed l:2 rispetto all'acido 5-ammino-2, 4, 6-triiodoisoftalico.Il dicloruro dell'acido 5-ammino-2, 4, 6-triiodoisoftalico è un intermedio utile per la preparazione di mezzi di contrasto iodurati.
ITMI942412A 1994-11-29 1994-11-29 Processo per la preparazione di un intermedio utile nella sintesi di composti organici IT1271107B (it)

Priority Applications (13)

Application Number Priority Date Filing Date Title
ITMI942412A IT1271107B (it) 1994-11-29 1994-11-29 Processo per la preparazione di un intermedio utile nella sintesi di composti organici
EP95939294A EP0794937B1 (en) 1994-11-29 1995-11-24 Process for preparing 5-amino-2,4,6-triiodoisophthalic acid dichloride by chlorination of the corresponding acid in the presence of a tertiary amine salt or quarternary ammonium salt
DE69508959T DE69508959T2 (de) 1994-11-29 1995-11-24 Verfahren zur herstellung von 5-amino-2,4,6-triiodoisophthalsäuredichlorid durch chlorierung der entsprechenden säure in gegenwart eines tertiären aminsalzes oder eines quaternären ammoniumsalzes
US08/836,984 US5856570A (en) 1994-11-29 1995-11-24 Process for preparing 5-amino-2,4,6-triiodoisophthalic acid dichloride by chlorination of the corresponding acid in the presence of a tertiary amine salt or quaternary ammonium salt
JP51816096A JP3795524B2 (ja) 1994-11-29 1995-11-24 第三級アミン塩又は第四級アンモニウム塩の存在下対応する酸の塩素化による５−アミノ−２，４，６−トリヨードイソフタル酸ジクロライドの製造法
ES95939294T ES2129877T3 (es) 1994-11-29 1995-11-24 Procedimiento para preparar dicloruro del acido 5-amino-2,4,6-triyodoisoftalico por cloracion del correspondiente acido en presencia de una sal de amina terciaria o una sal de amonio cuaternaria.
AT95939294T ATE178585T1 (de) 1994-11-29 1995-11-24 Verfahren zur herstellung von 5-amino-2,4,6- triiodoisophthalsäuredichlorid durch chlorierung der entsprechenden säure in gegenwart eines tertiären aminsalzes oder eines quaternären ammoniumsalzes
CZ19971637A CZ288587B6 (cs) 1994-11-29 1995-11-24 Způsob výroby dichloridu kyseliny 5-amino-2,4,6-trijodizoftalové
PCT/EP1995/004635 WO1996016927A1 (en) 1994-11-29 1995-11-24 Process for preparing 5-amino-2,4,6-triiodoisophthalic acid dichloride by chlorination of the corresponding acid in the presence of a tertiary amine salt or quarternary ammonium salt
IL11616695A IL116166A (en) 1994-11-29 1995-11-28 Process for the preparation of 5-amino-2,4,6- triiodoisophthalic acid dichloride
ZA9510152A ZA9510152B (en) 1994-11-29 1995-11-29 Process for the preparation of an intermediate useful in the synthesis of organic compounds
FI972261A FI972261A (fi) 1994-11-29 1997-05-28 Menetelmä 5-amino-2,4,6-trijodi-isoftaalihappodikloridin valmistamiseksi klooraamalla vastaavaa happoa tertiäärisen amiinisuolan tai kvaternäärisen ammoniumsuolan läsnäollessa
NO972428A NO308212B1 (no) 1994-11-29 1997-05-28 FremgangsmÕte for fremstilling av 5-amino-2,4,6- trijodisoftalsyrediklorid ved klorering av den tilsvarende syre

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI942412A IT1271107B (it) 1994-11-29 1994-11-29 Processo per la preparazione di un intermedio utile nella sintesi di composti organici

Publications (3)

Publication Number Publication Date
ITMI942412A0 ITMI942412A0 (it) 1994-11-29
ITMI942412A1 ITMI942412A1 (it) 1996-05-29
IT1271107B true IT1271107B (it) 1997-05-26

Family

ID=11369927

Family Applications (1)

Application Number Title Priority Date Filing Date
ITMI942412A IT1271107B (it) 1994-11-29 1994-11-29 Processo per la preparazione di un intermedio utile nella sintesi di composti organici

Country Status (13)

Country Link
US (1) US5856570A (it)
EP (1) EP0794937B1 (it)
JP (1) JP3795524B2 (it)
AT (1) ATE178585T1 (it)
CZ (1) CZ288587B6 (it)
DE (1) DE69508959T2 (it)
ES (1) ES2129877T3 (it)
FI (1) FI972261A (it)
IL (1) IL116166A (it)
IT (1) IT1271107B (it)
NO (1) NO308212B1 (it)
WO (1) WO1996016927A1 (it)
ZA (1) ZA9510152B (it)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1275429B (it) * 1995-05-18 1997-08-07 Zambon Spa Processo per la preparazione di un intermedio utile nella sintesi di composti organici
BR9606488A (pt) * 1995-05-23 1997-11-25 Fructamine Spa Processo para a preparação de um dicloreto de ácido dicarboxílico
KR20000075115A (ko) * 1999-05-28 2000-12-15 강재헌 불순물 ｃ가 제거된 이오파미돌의 신규 제조방법
WO2012136813A2 (en) 2011-04-07 2012-10-11 Universitetet I Oslo Agents for medical radar diagnosis
PT105770B (pt) * 2011-06-24 2013-07-08 Hovione Farmaciencia S A Novo intermediário e seu uso na preparação de agente de contrate triiodado
DK2931696T3 (en) 2012-12-11 2018-12-17 Bracco Imaging Spa CONTINUOUS PROCEDURE FOR THE PREPARATION OF (S) -2-ACETYLOXYPROPIONIC ACID
NZ726674A (en) 2014-06-10 2022-12-23 Bracco Imaging Spa Method for the preparation of (s)-2-acetyloxypropionic acid and derivatives thereof
CN104230731B (zh) * 2014-09-24 2016-01-20 武汉理工大学 造影剂中间体三碘异酞酰氯的制备方法
FR3062850B1 (fr) 2017-02-10 2020-01-31 Guerbet Procede de preparation monotope de composes organo-iodes
FR3084668A1 (fr) 2018-08-02 2020-02-07 Guerbet Procede de preparation monotope de composes organo-iodes intermediaires a la synthese du ioversol

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1193211B (it) * 1979-08-09 1988-06-15 Bracco Ind Chimica Spa Derivati dell'acido 2,4,6-triiodo-isoftalico,metodo per la loro preparazione e mezzi di contrasto che li contengono
US4396598A (en) * 1982-01-11 1983-08-02 Mallinckrodt, Inc. Triiodoisophthalamide X-ray contrast agent
FR2541676A1 (fr) * 1983-02-25 1984-08-31 Guerbet Sa Composes non-ioniques a structures benzenique iodee ou bromee et produits opacifiants en contenant
BR9606488A (pt) * 1995-05-23 1997-11-25 Fructamine Spa Processo para a preparação de um dicloreto de ácido dicarboxílico

Also Published As

Publication number Publication date
NO972428L (no) 1997-05-28
ES2129877T3 (es) 1999-06-16
FI972261A0 (fi) 1997-05-28
DE69508959D1 (de) 1999-05-12
NO972428D0 (no) 1997-05-28
JPH10509967A (ja) 1998-09-29
CZ288587B6 (cs) 2001-07-11
WO1996016927A1 (en) 1996-06-06
ATE178585T1 (de) 1999-04-15
NO308212B1 (no) 2000-08-14
DE69508959T2 (de) 1999-08-05
IL116166A (en) 1999-11-30
EP0794937A1 (en) 1997-09-17
ZA9510152B (en) 1996-06-12
CZ163797A3 (cs) 1998-02-18
US5856570A (en) 1999-01-05
ITMI942412A0 (it) 1994-11-29
FI972261A (fi) 1997-05-28
EP0794937B1 (en) 1999-04-07
JP3795524B2 (ja) 2006-07-12
IL116166A0 (en) 1996-01-31
ITMI942412A1 (it) 1996-05-29

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TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19971126