DE69508959T2 - Verfahren zur herstellung von 5-amino-2,4,6-triiodoisophthalsäuredichlorid durch chlorierung der entsprechenden säure in gegenwart eines tertiären aminsalzes oder eines quaternären ammoniumsalzes - Google Patents
Verfahren zur herstellung von 5-amino-2,4,6-triiodoisophthalsäuredichlorid durch chlorierung der entsprechenden säure in gegenwart eines tertiären aminsalzes oder eines quaternären ammoniumsalzesInfo
- Publication number
- DE69508959T2 DE69508959T2 DE69508959T DE69508959T DE69508959T2 DE 69508959 T2 DE69508959 T2 DE 69508959T2 DE 69508959 T DE69508959 T DE 69508959T DE 69508959 T DE69508959 T DE 69508959T DE 69508959 T2 DE69508959 T2 DE 69508959T2
- Authority
- DE
- Germany
- Prior art keywords
- amino
- chlorinating
- tertiary amine
- pct
- quaterial
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
- C07C227/18—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions involving amino or carboxyl groups, e.g. hydrolysis of esters or amides, by formation of halides, salts or esters
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITMI942412A IT1271107B (it) | 1994-11-29 | 1994-11-29 | Processo per la preparazione di un intermedio utile nella sintesi di composti organici |
PCT/EP1995/004635 WO1996016927A1 (en) | 1994-11-29 | 1995-11-24 | Process for preparing 5-amino-2,4,6-triiodoisophthalic acid dichloride by chlorination of the corresponding acid in the presence of a tertiary amine salt or quarternary ammonium salt |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69508959D1 DE69508959D1 (de) | 1999-05-12 |
DE69508959T2 true DE69508959T2 (de) | 1999-08-05 |
Family
ID=11369927
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69508959T Expired - Lifetime DE69508959T2 (de) | 1994-11-29 | 1995-11-24 | Verfahren zur herstellung von 5-amino-2,4,6-triiodoisophthalsäuredichlorid durch chlorierung der entsprechenden säure in gegenwart eines tertiären aminsalzes oder eines quaternären ammoniumsalzes |
Country Status (13)
Country | Link |
---|---|
US (1) | US5856570A (de) |
EP (1) | EP0794937B1 (de) |
JP (1) | JP3795524B2 (de) |
AT (1) | ATE178585T1 (de) |
CZ (1) | CZ288587B6 (de) |
DE (1) | DE69508959T2 (de) |
ES (1) | ES2129877T3 (de) |
FI (1) | FI972261A (de) |
IL (1) | IL116166A (de) |
IT (1) | IT1271107B (de) |
NO (1) | NO308212B1 (de) |
WO (1) | WO1996016927A1 (de) |
ZA (1) | ZA9510152B (de) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19681399B4 (de) * | 1995-05-18 | 2008-08-28 | Bracco Imaging S.P.A. | Verfahren zur Herstellung von 5-Amino-2,4,6-triiodisophthalsäuredichlorid durch Chlorierung mit Thionylchlorid in Anwesenheit eines Katalysators |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1996037459A1 (en) * | 1995-05-23 | 1996-11-28 | Fructamine S.P.A. | Process for the preparation of a dicarboxylic acid dichloride |
KR20000075115A (ko) * | 1999-05-28 | 2000-12-15 | 강재헌 | 불순물 c가 제거된 이오파미돌의 신규 제조방법 |
WO2012136813A2 (en) | 2011-04-07 | 2012-10-11 | Universitetet I Oslo | Agents for medical radar diagnosis |
PT105770B (pt) * | 2011-06-24 | 2013-07-08 | Hovione Farmaciencia S A | Novo intermediário e seu uso na preparação de agente de contrate triiodado |
US9926257B2 (en) | 2012-12-11 | 2018-03-27 | Bracco Imaging S.P.A. | Continuous process for the preparation of (S)-2-acetyloxypropionic acid chloride |
PL3154928T3 (pl) | 2014-06-10 | 2020-08-24 | Bracco Imaging S.P.A | Sposób wytwarzania kwasu (S)-2-acetyloksypropionowego i jego pochodnych |
CN104230731B (zh) * | 2014-09-24 | 2016-01-20 | 武汉理工大学 | 造影剂中间体三碘异酞酰氯的制备方法 |
FR3062850B1 (fr) | 2017-02-10 | 2020-01-31 | Guerbet | Procede de preparation monotope de composes organo-iodes |
FR3084668A1 (fr) | 2018-08-02 | 2020-02-07 | Guerbet | Procede de preparation monotope de composes organo-iodes intermediaires a la synthese du ioversol |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1193211B (it) * | 1979-08-09 | 1988-06-15 | Bracco Ind Chimica Spa | Derivati dell'acido 2,4,6-triiodo-isoftalico,metodo per la loro preparazione e mezzi di contrasto che li contengono |
US4396598A (en) * | 1982-01-11 | 1983-08-02 | Mallinckrodt, Inc. | Triiodoisophthalamide X-ray contrast agent |
FR2541676A1 (fr) * | 1983-02-25 | 1984-08-31 | Guerbet Sa | Composes non-ioniques a structures benzenique iodee ou bromee et produits opacifiants en contenant |
WO1996037459A1 (en) * | 1995-05-23 | 1996-11-28 | Fructamine S.P.A. | Process for the preparation of a dicarboxylic acid dichloride |
-
1994
- 1994-11-29 IT ITMI942412A patent/IT1271107B/it active IP Right Grant
-
1995
- 1995-11-24 ES ES95939294T patent/ES2129877T3/es not_active Expired - Lifetime
- 1995-11-24 US US08/836,984 patent/US5856570A/en not_active Expired - Lifetime
- 1995-11-24 WO PCT/EP1995/004635 patent/WO1996016927A1/en active IP Right Grant
- 1995-11-24 EP EP95939294A patent/EP0794937B1/de not_active Expired - Lifetime
- 1995-11-24 CZ CZ19971637A patent/CZ288587B6/cs not_active IP Right Cessation
- 1995-11-24 AT AT95939294T patent/ATE178585T1/de active
- 1995-11-24 JP JP51816096A patent/JP3795524B2/ja not_active Expired - Lifetime
- 1995-11-24 DE DE69508959T patent/DE69508959T2/de not_active Expired - Lifetime
- 1995-11-28 IL IL11616695A patent/IL116166A/xx not_active IP Right Cessation
- 1995-11-29 ZA ZA9510152A patent/ZA9510152B/xx unknown
-
1997
- 1997-05-28 NO NO972428A patent/NO308212B1/no not_active IP Right Cessation
- 1997-05-28 FI FI972261A patent/FI972261A/fi not_active Application Discontinuation
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19681399B4 (de) * | 1995-05-18 | 2008-08-28 | Bracco Imaging S.P.A. | Verfahren zur Herstellung von 5-Amino-2,4,6-triiodisophthalsäuredichlorid durch Chlorierung mit Thionylchlorid in Anwesenheit eines Katalysators |
Also Published As
Publication number | Publication date |
---|---|
ITMI942412A0 (it) | 1994-11-29 |
CZ163797A3 (cs) | 1998-02-18 |
NO308212B1 (no) | 2000-08-14 |
NO972428L (no) | 1997-05-28 |
IT1271107B (it) | 1997-05-26 |
DE69508959D1 (de) | 1999-05-12 |
JP3795524B2 (ja) | 2006-07-12 |
WO1996016927A1 (en) | 1996-06-06 |
ZA9510152B (en) | 1996-06-12 |
FI972261A0 (fi) | 1997-05-28 |
IL116166A0 (en) | 1996-01-31 |
NO972428D0 (no) | 1997-05-28 |
ITMI942412A1 (it) | 1996-05-29 |
EP0794937B1 (de) | 1999-04-07 |
EP0794937A1 (de) | 1997-09-17 |
CZ288587B6 (cs) | 2001-07-11 |
JPH10509967A (ja) | 1998-09-29 |
US5856570A (en) | 1999-01-05 |
FI972261A (fi) | 1997-05-28 |
ATE178585T1 (de) | 1999-04-15 |
IL116166A (en) | 1999-11-30 |
ES2129877T3 (es) | 1999-06-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8327 | Change in the person/name/address of the patent owner |
Owner name: BRACCO IMAGING S.P.A., MAILAND/MILANO, IT |