CH587021A5
(es)
|
1974-06-07 |
1977-04-29 |
Nestle Sa |
|
EP0173552B1
(en)
|
1984-08-24 |
1991-10-09 |
The Upjohn Company |
Recombinant dna compounds and the expression of polypeptides such as tpa
|
US5168062A
(en)
|
1985-01-30 |
1992-12-01 |
University Of Iowa Research Foundation |
Transfer vectors and microorganisms containing human cytomegalovirus immediate-early promoter-regulatory DNA sequence
|
US5651991A
(en)
|
1987-10-28 |
1997-07-29 |
Nippon Shinyaku Co. Ltd. |
Drug carriers
|
US5549910A
(en)
|
1989-03-31 |
1996-08-27 |
The Regents Of The University Of California |
Preparation of liposome and lipid complex compositions
|
US5252334A
(en)
|
1989-09-08 |
1993-10-12 |
Cygnus Therapeutic Systems |
Solid matrix system for transdermal drug delivery
|
JP3218637B2
(ja)
|
1990-07-26 |
2001-10-15 |
大正製薬株式会社 |
安定なリポソーム水懸濁液
|
JP2958076B2
(ja)
|
1990-08-27 |
1999-10-06 |
株式会社ビタミン研究所 |
遺伝子導入用多重膜リポソーム及び遺伝子捕捉多重膜リポソーム製剤並びにその製法
|
CA2091152C
(en)
|
1993-03-05 |
2005-05-03 |
Kirsten Westesen |
Solid lipid particles, particles of bioactive agents and methods for the manfuacture and use thereof
|
JPH07285863A
(ja)
|
1994-02-25 |
1995-10-31 |
Takeda Chem Ind Ltd |
注射剤組成物およびその製造方法
|
ES2078190B1
(es)
|
1994-05-20 |
1996-08-01 |
Cusi Lab |
Procedimiento para el recubrimiento de goticulas o particulas de tamaño nanometrico.
|
US5741516A
(en)
|
1994-06-20 |
1998-04-21 |
Inex Pharmaceuticals Corporation |
Sphingosomes for enhanced drug delivery
|
US5795587A
(en)
|
1995-01-23 |
1998-08-18 |
University Of Pittsburgh |
Stable lipid-comprising drug delivery complexes and methods for their production
|
US5697899A
(en)
|
1995-02-07 |
1997-12-16 |
Gensia |
Feedback controlled drug delivery system
|
US5510118A
(en)
|
1995-02-14 |
1996-04-23 |
Nanosystems Llc |
Process for preparing therapeutic compositions containing nanoparticles
|
US5738868A
(en)
|
1995-07-18 |
1998-04-14 |
Lipogenics Ltd. |
Liposome compositions and kits therefor
|
US5656016A
(en)
|
1996-03-18 |
1997-08-12 |
Abbott Laboratories |
Sonophoretic drug delivery system
|
US5797898A
(en)
|
1996-07-02 |
1998-08-25 |
Massachusetts Institute Of Technology |
Microchip drug delivery devices
|
US5783208A
(en)
|
1996-07-19 |
1998-07-21 |
Theratech, Inc. |
Transdermal drug delivery matrix for coadministering estradiol and another steroid
|
US5779708A
(en)
|
1996-08-15 |
1998-07-14 |
Cyberdent, Inc. |
Intraosseous drug delivery device and method
|
WO1998010088A1
(en)
|
1996-09-06 |
1998-03-12 |
Trustees Of The University Of Pennsylvania |
An inducible method for production of recombinant adeno-associated viruses utilizing t7 polymerase
|
US6007856A
(en)
|
1997-08-08 |
1999-12-28 |
The Procter & Gamble Company |
Oil-in-water dispersions of β-carotene and other carotenoids stable against oxidation prepared from water-dispersible beadlets having high concentrations of carotenoid
|
DE59914485D1
(de)
|
1998-03-30 |
2007-10-18 |
Mibelle Ag Cosmetics |
Verwendung von Nanoemulsionen zur Bestimmung der Biokompatibilität von lipophilen Stoffen im Zellkultur-Test und dafür geeignete Nanoemulsionen
|
US6436392B1
(en)
|
1998-05-20 |
2002-08-20 |
University Of Iowa Research Foundation |
Adeno-associated virus vectors
|
US8026096B1
(en)
|
1998-10-08 |
2011-09-27 |
Protein Sciences Corporation |
In vivo active erythropoietin produced in insect cells
|
ATE226449T1
(de)
|
1998-12-03 |
2002-11-15 |
Avigen Inc |
Hilfsstoffe zur verwendung in adeno-assoziiertes virus enthaltenden pharmazeutischen zubereitungen und damit hergestellte pharmazeutische zubereitungen
|
FR2787728B1
(fr)
|
1998-12-23 |
2001-01-26 |
Oreal |
Nanoemulsion a base d'esters gras d'acide phosphorique, et ses utilisations dans les domaines cosmetique, dermatologique, pharmaceutique et/ou ophtalmologique
|
US6258595B1
(en)
|
1999-03-18 |
2001-07-10 |
The Trustees Of The University Of Pennsylvania |
Compositions and methods for helper-free production of recombinant adeno-associated viruses
|
AU7739000A
(en)
|
1999-10-01 |
2001-05-10 |
University Of Florida |
Temperature-sensitive regulation of viral vector production
|
WO2001049829A1
(en)
|
2000-01-05 |
2001-07-12 |
Fred Hutchinson Cancer Research Center |
Compositions and methods for efficient aav vector production
|
AU2001240018A1
(en)
|
2000-03-03 |
2001-09-17 |
The Board Of Trustees Of The Leland Stanford Junior University |
Adeno-associated viral compositions and methods
|
EP1267830B1
(en)
|
2000-03-23 |
2009-05-27 |
Basf Catalysts Llc |
Method for preparing high pressure/high shear dispersions containing physiologically active ingredients
|
WO2001070972A2
(en)
|
2000-03-24 |
2001-09-27 |
Yasunaga, Shin'ichiro |
Multiple human and mouse otoferlin isoforms
|
RS49646B
(sr)
|
2000-07-04 |
2007-09-21 |
Slobodan Arsenijević |
Instrument za ubrizgavanje fluida i dilataciona sonda za uvođenje u telesne šupljine
|
FR2811561B1
(fr)
|
2000-07-13 |
2003-03-21 |
Oreal |
Composition, notamment cosmetique, renfermant la dhea et/ou un precurseur ou derive chimique ou biologique de celle-ci, et un inhibiteur de metalloproteinase
|
US6329181B1
(en)
|
2000-08-07 |
2001-12-11 |
Neurologix, Inc. |
Helper functions for recombinant vector production
|
US6593123B1
(en)
|
2000-08-07 |
2003-07-15 |
Avigen, Inc. |
Large-scale recombinant adeno-associated virus (rAAV) production and purification
|
US20040048836A1
(en)
|
2001-03-23 |
2004-03-11 |
Wilmott James M |
Method for preparing high pressure/ high shear dispersions containing physiologically active ingredients
|
JP4444565B2
(ja)
|
2001-03-30 |
2010-03-31 |
カラー アクセス,インコーポレイティド |
新規ナノエマルション
|
KR100463167B1
(ko)
|
2001-04-13 |
2004-12-23 |
주식회사 태평양 |
고분자 나노입자를 이용한 경피흡수제 및 이를 함유한외용제 조성물
|
JP2006512401A
(ja)
|
2001-06-05 |
2006-04-13 |
ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン |
ナノエマルジョンワクチン
|
JP2004538005A
(ja)
|
2001-08-08 |
2004-12-24 |
ザ・トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア |
シアル酸に結合するタンパク質を有するウイルスベクターの精製法
|
US20040115159A1
(en)
|
2002-03-29 |
2004-06-17 |
Tadlock Charles C |
Novel nanoemulsions
|
WO2003093295A2
(en)
|
2002-04-30 |
2003-11-13 |
University Of North Carolina At Chapel Hill |
Secretion signal vectors
|
US7419817B2
(en)
|
2002-05-17 |
2008-09-02 |
The United States Of America As Represented By The Secretary Department Of Health And Human Services, Nih. |
Scalable purification of AAV2, AAV4 or AAV5 using ion-exchange chromatography
|
RU2349608C2
(ru)
|
2002-09-12 |
2009-03-20 |
Зм Инновейтив Пропертиз Компани |
Фторэластомеры, имеющие низкотемпературные характеристики и устойчивость к растворителям
|
US7329688B2
(en)
|
2002-12-17 |
2008-02-12 |
Soft Gel Technologies, Inc. |
Natural vitamin E compositions with superior antioxidant potency
|
PT1625210E
(pt)
|
2003-05-21 |
2011-03-15 |
Genzyme Corp |
Métodos para produzir preparações de vírions de aav recombinantes substancialmente livres de capsídeos vazios
|
WO2005027872A2
(en)
|
2003-06-04 |
2005-03-31 |
Nanobio Corporation |
Compositions for inactivating pathogenic microorganisms, methods of making the compositions, and methods of use thereof
|
JPWO2005013938A1
(ja)
|
2003-08-06 |
2006-09-28 |
エーザイ株式会社 |
薬物超微粒子の製造法及び製造装置
|
US7387614B2
(en)
|
2003-08-26 |
2008-06-17 |
University Of Maryland, Baltimore |
Drug delivery to the inner ear and methods of using same
|
EP1510206A1
(en)
|
2003-08-29 |
2005-03-02 |
Novagali Pharma SA |
Self-nanoemulsifying oily formulation for the administration of poorly water-soluble drugs
|
CA2543722C
(en)
|
2003-10-29 |
2011-01-04 |
Sonus Pharmaceuticals, Inc. |
Tocopherol-modified therapeutic drug compounds
|
US7557197B2
(en)
|
2004-01-28 |
2009-07-07 |
Oregon Health & Science University |
Human soluble neuropilin-1 primary polyadenylation signal and uses thereof
|
US7118688B2
(en)
|
2004-02-23 |
2006-10-10 |
The Texas A&M University System |
Antioxidant compositions and methods of use thereof
|
US7419497B2
(en)
|
2004-04-21 |
2008-09-02 |
Acclarent, Inc. |
Methods for treating ethmoid disease
|
BRPI0511764B8
(pt)
|
2004-06-01 |
2021-05-25 |
Avigen Inc |
método de prevenção de agregação de vírions de vírus adeno-associado recombinante (raav) em uma preparação purificada de virions raav
|
WO2006033689A2
(en)
|
2004-06-18 |
2006-03-30 |
The University Of Montana |
Aav mediated gene delivery to cochlear cells
|
WO2006012414A2
(en)
|
2004-07-20 |
2006-02-02 |
Critical Therapeutics, Inc. |
Novel polyadenylation signal for use in expression vectors
|
US8591457B2
(en)
|
2005-08-10 |
2013-11-26 |
Alza Corporation |
Method for making a needle-free jet injection drug delivery device
|
AU2006304997B2
(en)
|
2005-10-20 |
2012-03-01 |
Uniqure Ip B.V. |
Improved AAV vectors produced in insect cells
|
ES2400235T3
(es)
|
2006-04-28 |
2013-04-08 |
The Trustees Of The University Of Pennsylvania |
Método de producción escalable de AAV
|
US7851196B2
(en)
|
2006-05-01 |
2010-12-14 |
The Regents Of The University Of California |
Methods for purifying adeno-associated virus particles
|
ES2785223T3
(es)
|
2006-06-21 |
2020-10-06 |
Uniqure Ip Bv |
Células de insecto para la producción de vectores de AAV
|
US20080065002A1
(en)
|
2006-09-07 |
2008-03-13 |
Neurosystec Corporation |
Catheter for Localized Drug Delivery and/or Electrical Stimulation
|
JP5634262B2
(ja)
|
2007-07-26 |
2014-12-03 |
ユニキュアー アイピー ビー.ブイ. |
差次的コドンバイアスを有する反復コード配列を含むバキュロウイルスベクター
|
US20090042825A1
(en)
|
2007-08-06 |
2009-02-12 |
Majed Matar |
Composition, method of preparation & application of concentrated formulations of condensed nucleic acids with a cationic lipopolymer
|
US8236557B2
(en)
|
2008-05-28 |
2012-08-07 |
University Of Missouri-Columbia |
Hybrid-AAV vectors to deliver large gene expression cassette
|
EA020311B1
(ru)
|
2008-11-28 |
2014-10-30 |
Антон Бауэр |
Вектор на основе искусственной хромосомы
|
HUE028341T2
(en)
|
2009-06-16 |
2016-12-28 |
Genzyme Corp |
Improved methods for purifying recombinant AAV vectors
|
JP5697123B2
(ja)
|
2009-07-27 |
2015-04-08 |
国立大学法人 千葉大学 |
酸性化ポリエチレンイミンを用いる細胞への核酸導入方法
|
WO2011075838A1
(en)
|
2009-12-21 |
2011-06-30 |
Audigen Inc. |
Method of treating or preventing hearing loss
|
CN105838737A
(zh)
|
2010-01-28 |
2016-08-10 |
费城儿童医院 |
用于病毒载体纯化的可扩缩生产平台和用于基因治疗中的如此纯化的病毒载体
|
US9228174B2
(en)
|
2010-03-11 |
2016-01-05 |
Uniqure Ip B.V. |
Mutated rep encoding sequences for use in AAV production
|
US20130225905A1
(en)
|
2010-08-19 |
2013-08-29 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Device that is implantable in the temporal bone for delivering a material, and hearing aid provided with such a device
|
EP2500434A1
(en)
|
2011-03-12 |
2012-09-19 |
Association Institut de Myologie |
Capsid-free AAV vectors, compositions, and methods for vector production and gene delivery
|
US8852165B2
(en)
|
2011-06-16 |
2014-10-07 |
II Edward G. Mackay |
Endoluminal drug delivery devices and methods
|
US9441206B2
(en)
|
2011-10-28 |
2016-09-13 |
The University Of North Carolina At Chapel Hill |
Cell line for production of adeno-associated virus
|
WO2013075008A1
(en)
|
2011-11-16 |
2013-05-23 |
University Of Florida Research Foundation Inc. |
Aav dual vector systems for gene therapy
|
CA2864879C
(en)
|
2012-02-17 |
2021-07-20 |
The Children's Hospital Of Philadelphia |
Aav vector compositions and methods for gene transfer to cells, organs and tissues
|
US11332719B2
(en)
|
2013-03-15 |
2022-05-17 |
The Broad Institute, Inc. |
Recombinant virus and preparations thereof
|
ES2704677T3
(es)
|
2013-04-18 |
2019-03-19 |
Fond Telethon |
Suministro eficaz de genes grandes por vectores de AAV duales
|
US11078464B2
(en)
|
2013-08-30 |
2021-08-03 |
Amgen Inc. |
High titer recombinant AAV vector production in adherent and suspension cells
|
HUE052676T2
(hu)
|
2013-10-11 |
2021-05-28 |
Massachusetts Eye & Ear Infirmary |
Eljárások õsi vírusszekvenciák elõrejelzésére és alkalmazásaik
|
CN106459984B
(zh)
|
2014-03-10 |
2021-09-07 |
优尼科Ip有限公司 |
昆虫细胞中产生的进一步改善的aav载体
|
US10526583B2
(en)
|
2014-07-02 |
2020-01-07 |
University Of Florida Research Foundation, Incorporated |
Compositions and methods for purifying recombinant adeno-associated virus
|
CN107428799A
(zh)
|
2015-01-13 |
2017-12-01 |
阿尔法韦士曼公司 |
纯化腺相关病毒(AAV)及/或重组腺相关病毒(rAAV)之方法及其梯度和流通式缓冲液
|
EP3054006A1
(en)
|
2015-02-09 |
2016-08-10 |
Institut National De La Sante Et De La Recherche Medicale (Inserm) |
Recombinant adeno-associated virus particle purification with multiple-step anion exchange chromatography
|
US10751385B2
(en)
|
2015-02-20 |
2020-08-25 |
Institut Pasteur |
Prevention and/or treatment of hearing loss or impairment
|
EP3265571B1
(en)
|
2015-03-03 |
2022-04-13 |
Fondazione Telethon |
Multiple vector system and uses thereof
|
EP3748007A1
(en)
|
2015-03-06 |
2020-12-09 |
Massachusetts Eye & Ear Infirmary |
Gene augmentation therapies for inherited retinal degeneration caused by mutations in the prpf31 gene
|
EP3872085B1
(en)
|
2015-07-30 |
2023-03-01 |
Massachusetts Eye & Ear Infirmary |
Ancestral aav sequences and uses thereof
|
MX2018006682A
(es)
|
2015-12-01 |
2018-09-26 |
Spark Therapeutics Inc |
Metodos escalables para producir vector viral adenoasociado (aav) recombinante en un sistema de cultivo celular en suspension libre de suero adecuado para su uso clinico.
|
US11167042B2
(en)
|
2015-12-11 |
2021-11-09 |
Massachusetts Eye And Ear Infirmary |
Materials and methods for delivering nucleic acids to cochlear and vestibular cells
|
US11072803B2
(en)
|
2015-12-22 |
2021-07-27 |
Inserm (Institut National De La Sante Et De La Recherche Medicale) |
Hybrid dual recombinant AAV vector systems for gene therapy
|
WO2017132530A1
(en)
|
2016-01-29 |
2017-08-03 |
Massachusetts Eye And Ear Infirmary |
Expansion and differentiation of inner ear supporting cells and methods of use thereof
|
US20190038778A1
(en)
|
2016-02-05 |
2019-02-07 |
The General Hospital Corporation |
Hybrid System for Efficient Gene Delivery to Cells of the Inner Ear
|
US10201455B2
(en)
|
2016-06-22 |
2019-02-12 |
The Charles Stark Draper Laboratory, Inc. |
System for inner ear drug delivery via trans-round window membrane injection
|
GB201612248D0
(en)
|
2016-07-14 |
2016-08-31 |
Puridify Ltd |
New process
|
JP7153009B2
(ja)
|
2016-07-21 |
2022-10-13 |
スパーク セラピューティクス インコーポレイテッド |
高収率の組換えアデノ随伴ウイルス(rAAV)ベクターを生成するための、規模拡大可能な高回収率の方法、及びそれにより生成される組換えアデノ随伴ウイルス(rAAV)ベクター
|
JP6994018B2
(ja)
|
2016-07-26 |
2022-01-14 |
バイオマリン ファーマシューティカル インコーポレイテッド |
新規アデノ随伴ウイルスキャプシドタンパク質
|
JP2019530737A
(ja)
*
|
2016-08-23 |
2019-10-24 |
アコーオス インコーポレイテッド |
ヒト対象において非加齢性聴力障害を治療するための組成物および方法
|
US11125139B2
(en)
*
|
2016-10-24 |
2021-09-21 |
Cummins Inc. |
Waste heat recovery vehicle cooling optimization
|
PT3535388T
(pt)
|
2016-11-04 |
2023-06-27 |
Takeda Pharmaceuticals Co |
Métodos de purificação de vírus adeno-associados
|
US10626376B2
(en)
|
2016-11-14 |
2020-04-21 |
St. Jude Children's Research Hospital |
Method for isolating and purifying adeno-associated virus particles using salt
|
WO2018145111A1
(en)
|
2017-02-06 |
2018-08-09 |
Children's Medical Center Corporation |
Materials and methods for delivering nucleic acids to cochlear and vestibular cells
|
JP2020518258A
(ja)
|
2017-05-05 |
2020-06-25 |
ボイジャー セラピューティクス インコーポレイテッドVoyager Therapeutics,Inc. |
筋萎縮性側索硬化症(als)治療組成物および方法
|
SG11201909868YA
(en)
|
2017-05-05 |
2019-11-28 |
Voyager Therapeutics Inc |
Compositions and methods of treating huntington's disease
|
EP3619310A4
(en)
|
2017-05-05 |
2021-01-27 |
Voyager Therapeutics, Inc. |
MODULATORY POLYNUCLEOTIDES
|
CN110892062A
(zh)
|
2017-05-05 |
2020-03-17 |
佛罗里达大学研究基金会 |
表达耳畸蛋白的组合物和方法
|
JOP20190269A1
(ar)
|
2017-06-15 |
2019-11-20 |
Voyager Therapeutics Inc |
بولي نوكليوتيدات aadc لعلاج مرض باركنسون
|
KR20200044793A
(ko)
|
2017-08-03 |
2020-04-29 |
보이저 테라퓨틱스, 인크. |
Aav의 전달을 위한 조성물 및 방법
|
WO2019084145A1
(en)
|
2017-10-25 |
2019-05-02 |
The Charles Stark Draper Laboratory Inc. |
APPARATUS AND METHOD FOR DRUG DELIVERY ACROSS THE ROUND WINDOW MEMBRANE
|
EP3740581A4
(en)
|
2018-01-16 |
2021-10-27 |
CLS Therapeutics Limited |
TREATMENT OF DISEASES BY LIVER EXPRESSION OF AN ENZYME WITH DESOXYRIBONUCLEASE (DNASE) ACTIVITY
|
SG11202007595WA
(en)
|
2018-02-09 |
2020-09-29 |
Decibel Therapeutics Inc |
Hypertonic pharmaceutical compositions containing an anti-platinum chemoprotectant agent
|
DE102018103924A1
(de)
|
2018-02-21 |
2019-08-22 |
Georg-August-Universität Göttingen Stiftung Öffentlichen Rechts, Universitätsmedizin |
Gentherapeutische Behandlung von Schwerhörigkeit
|
AU2019224121A1
(en)
|
2018-02-22 |
2020-08-27 |
Akouos, Inc. |
Compositions and methods for treating non-age-associated hearing impairment in a human subject
|
CN112423791A
(zh)
|
2018-03-05 |
2021-02-26 |
儿童医疗中心有限公司 |
将核酸递送至耳蜗和前庭细胞的组合物和方法
|
US11660353B2
(en)
|
2018-04-27 |
2023-05-30 |
Decibel Therapeutics, Inc. |
Compositions and methods for treating sensorineural hearing loss using otoferlin dual vector systems
|
AU2019257782A1
(en)
|
2018-04-27 |
2020-11-19 |
Decibel Therapeutics, Inc. |
Myosin 15 promoters and uses thereof
|
SG11202011296VA
(en)
|
2018-05-15 |
2020-12-30 |
Voyager Therapeutics Inc |
Compositions and methods for the treatment of parkinson's disease
|
US20210230632A1
(en)
|
2018-05-15 |
2021-07-29 |
Voyager Therapeutics, Inc. |
Compositions and methods for delivery of aav
|
WO2020014479A1
(en)
|
2018-07-11 |
2020-01-16 |
Baxalta Incorporated |
Aav compositions
|
US20210355454A1
(en)
|
2018-07-24 |
2021-11-18 |
Voyager Therapeutics, Inc. |
Systems and methods for producing gene therapy formulations
|
EP3856227A4
(en)
|
2018-09-27 |
2022-07-06 |
Akouos, Inc. |
METHOD OF TREATMENT OF AN AUDITORY NEUROPATHY SPECTRUM DISORDER
|
WO2020077295A1
(en)
|
2018-10-11 |
2020-04-16 |
Decibel Therapeutics, Inc. |
Aav1 vectors and uses thereof for treatment of otic indications
|
US20210395778A1
(en)
|
2018-11-01 |
2021-12-23 |
University Of Florida Research Foundation, Incorporated |
A codon optimized otoferlin aav dual vector gene therapy
|
EP3880826A4
(en)
|
2018-11-07 |
2022-08-24 |
Akouos, Inc. |
USE OF ADENO-ASSOCIATED VIRAL VECTORS TO CORRECT GENE DEFECTS/EXPRESS PROTEINS IN CILIATE AND SUPPORTING CELLS IN THE INNER EAR
|
EP4295913A3
(en)
|
2019-01-18 |
2024-03-06 |
Institut Pasteur |
Aav-mediated gene therapy restoring the otoferlin gene
|
CN110437317B
(zh)
|
2019-01-30 |
2023-05-02 |
上海科技大学 |
具有变异衣壳蛋白的腺相关病毒及其用途
|
US20210388045A1
(en)
|
2019-02-08 |
2021-12-16 |
Decibel Therapeutics, Inc. |
Myosin 15 promoters and uses thereof
|
WO2020163743A1
(en)
|
2019-02-08 |
2020-08-13 |
Decibel Therapeutics, Inc. |
Compositions and methods for treating sensorineural hearing loss using otoferlin dual vector systems
|
WO2020163761A1
(en)
|
2019-02-08 |
2020-08-13 |
Decibel Therapeutics, Inc. |
Myosin 15 promoters and uses thereof
|
EP3967706A4
(en)
|
2019-05-08 |
2022-12-28 |
Center For Excellence In Brain Science And Intelligence Technology, Chinese Academy Of Sciences |
AAV MUTANT FOR EFFICIENT INFECTION OF SUPPORT CELLS
|
IL291789A
(en)
|
2019-09-30 |
2022-06-01 |
Applied Genetic Tech Corporation |
Adeno-associated virus (aav) systems for the treatment of genetic hearing loss
|
JP2022552015A
(ja)
|
2019-10-18 |
2022-12-14 |
リサーチ インスティチュート アット ネイションワイド チルドレンズ ホスピタル |
蝸牛細胞を標的とする遺伝子治療
|
WO2021087296A1
(en)
|
2019-10-30 |
2021-05-06 |
Decibel Therapeutics, Inc. |
Compositions and methods for treating sensorineural hearing loss using otoferlin dual vector systems
|
BR112022009006A2
(pt)
|
2019-11-11 |
2022-10-11 |
Salk Inst For Biological Studi |
Composições e métodos para recombinação de alta eficiência de moléculas de rna
|
WO2021150850A1
(en)
|
2020-01-24 |
2021-07-29 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Svcs. |
Adeno-associated viruses and their uses for inner ear therapy
|
KR20220141829A
(ko)
|
2020-02-07 |
2022-10-20 |
유니버시티 오브 로체스터 |
리보자임-매개 rna 조립 및 발현
|
EP4100518A2
(en)
|
2020-02-07 |
2022-12-14 |
The Children's Medical Center Corporation |
Large gene vectors and delivery and uses thereof
|
AU2021225035A1
(en)
|
2020-02-21 |
2022-10-13 |
Akouos, Inc. |
Compositions and methods for treating non-age-associated hearing impairment in a human subject
|
US20210284699A1
(en)
|
2020-03-12 |
2021-09-16 |
California Institute Of Technology |
Adeno-associated viral capsids with expanded sizes
|
CN111349148A
(zh)
|
2020-03-13 |
2020-06-30 |
辉大(上海)生物科技有限公司 |
一种腺相关病毒载体及其用途
|
EP3885440A1
(en)
|
2020-03-26 |
2021-09-29 |
Splicebio, S.L. |
Split inteins and their uses
|
WO2022056440A1
(en)
|
2020-09-14 |
2022-03-17 |
President And Fellows Of Harvard College |
Dual-aav vector delivery of pcdh15 and uses thereof
|
IL302653A
(en)
|
2020-11-06 |
2023-07-01 |
Lilly Co Eli |
ADENO-ASSOCIATED VARIANT POLYPEPTIDES (AAV) AND THEIR GENETIC THERAPIES FOR THE TREATMENT OF HEARING LOSS
|
EP4008788A1
(en)
|
2020-12-03 |
2022-06-08 |
Medizinische Hochschule Hannover |
Lentiviral vector technology for inner ear gene therapy
|
JP2024507837A
(ja)
|
2021-02-19 |
2024-02-21 |
デシベル セラピューティクス インコーポレイテッド |
オトフェリン二重ベクター系を使用して、感音難聴を治療するための組成物
|
CN113337507B
(zh)
|
2021-08-05 |
2021-11-12 |
首都医科大学附属北京友谊医院 |
Otof 1273 (C>T)基因定点突变的耳聋小鼠模型的构建方法及其应用
|