AR111776A1 - Heteroarilos inhibidores de las proteínas ras mutantes de g12c - Google Patents

Heteroarilos inhibidores de las proteínas ras mutantes de g12c

Info

Publication number
AR111776A1
AR111776A1 ARP180101198A ARP180101198A AR111776A1 AR 111776 A1 AR111776 A1 AR 111776A1 AR P180101198 A ARP180101198 A AR P180101198A AR P180101198 A ARP180101198 A AR P180101198A AR 111776 A1 AR111776 A1 AR 111776A1
Authority
AR
Argentina
Prior art keywords
alkyl
halo
hydroxy
heteroaryl
alkoxy
Prior art date
Application number
ARP180101198A
Other languages
English (en)
Spanish (es)
Inventor
Piotr Antoni Raubo
Graeme Richard Rob
Shaun Michael Fillery
Andrew John Eatherton
Scott Boyd
Sharanjeet Kaur Bagal
Jason Grant Kettle
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of AR111776A1 publication Critical patent/AR111776A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
ARP180101198A 2017-05-11 2018-05-08 Heteroarilos inhibidores de las proteínas ras mutantes de g12c AR111776A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201762504638P 2017-05-11 2017-05-11

Publications (1)

Publication Number Publication Date
AR111776A1 true AR111776A1 (es) 2019-08-21

Family

ID=62492577

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP180101198A AR111776A1 (es) 2017-05-11 2018-05-08 Heteroarilos inhibidores de las proteínas ras mutantes de g12c

Country Status (8)

Country Link
US (2) US20200109153A1 (enExample)
EP (1) EP3621968A1 (enExample)
JP (1) JP2020519589A (enExample)
CN (1) CN110603258A (enExample)
AR (1) AR111776A1 (enExample)
CA (1) CA3061650A1 (enExample)
TW (1) TW201906848A (enExample)
WO (1) WO2018206539A1 (enExample)

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Also Published As

Publication number Publication date
TW201906848A (zh) 2019-02-16
WO2018206539A1 (en) 2018-11-15
US20220127281A1 (en) 2022-04-28
CN110603258A (zh) 2019-12-20
JP2020519589A (ja) 2020-07-02
EP3621968A1 (en) 2020-03-18
US20200109153A1 (en) 2020-04-09
CA3061650A1 (en) 2018-11-15

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