AR091216A1 - Proteinas del factor 21 de crecimiento del fibroblasto - Google Patents

Proteinas del factor 21 de crecimiento del fibroblasto

Info

Publication number
AR091216A1
AR091216A1 ARP130101904A AR091216A1 AR 091216 A1 AR091216 A1 AR 091216A1 AR P130101904 A ARP130101904 A AR P130101904A AR 091216 A1 AR091216 A1 AR 091216A1
Authority
AR
Argentina
Prior art keywords
proteins
growth factor
fibroblasto
fgf21
homodimer
Prior art date
Application number
Other languages
English (en)
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=48670814&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AR091216(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of AR091216A1 publication Critical patent/AR091216A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/50—Fibroblast growth factor [FGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1825—Fibroblast growth factor [FGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/81—Carrier - bound or immobilized peptides or proteins and the preparation thereof, e.g. biological cell or cell fragment as carrier
    • Y10S530/812—Peptides or proteins is immobilized on, or in, an organic carrier
    • Y10S530/813—Carrier is a saccharide
    • Y10S530/814—Cellulose or derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

La presente se refiere a proteínas del factor 21 de crecimiento del fibroblasto humano (FGF21) farmacológicamente potentes y estables, composiciones farmacéuticas que comprenden las proteínas del FGF21, y métodos para tratar diabetes tipo 2, obesidad, dislipidemia, y/o síndrome metabólico usando tales proteínas. Molécula de ADN, célula, proceso para producir un homodímero.
ARP130101904 2012-06-11 2013-05-30 Proteinas del factor 21 de crecimiento del fibroblasto AR091216A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261658104P 2012-06-11 2012-06-11
US201361777386P 2013-03-12 2013-03-12

Publications (1)

Publication Number Publication Date
AR091216A1 true AR091216A1 (es) 2015-01-21

Family

ID=48670814

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP130101904 AR091216A1 (es) 2012-06-11 2013-05-30 Proteinas del factor 21 de crecimiento del fibroblasto

Country Status (24)

Country Link
US (2) US8741841B2 (es)
EP (1) EP2858662B1 (es)
JP (1) JP6182600B2 (es)
KR (1) KR20150006060A (es)
CN (1) CN104394882B (es)
AR (1) AR091216A1 (es)
AU (1) AU2013274638A1 (es)
BR (1) BR112014029966A2 (es)
CA (1) CA2871145A1 (es)
CL (1) CL2014003078A1 (es)
CO (1) CO7151525A2 (es)
EA (1) EA201492053A1 (es)
EC (1) ECSP14030742A (es)
ES (1) ES2644787T3 (es)
HK (1) HK1203357A1 (es)
IL (1) IL235832A0 (es)
IN (1) IN2014MN02132A (es)
MX (1) MX2014015257A (es)
PE (1) PE20150201A1 (es)
PH (1) PH12014502766A1 (es)
SG (1) SG11201408095XA (es)
TN (1) TN2014000439A1 (es)
TW (1) TWI513705B (es)
WO (1) WO2013188181A1 (es)

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US9273107B2 (en) 2012-12-27 2016-03-01 Ngm Biopharmaceuticals, Inc. Uses and methods for modulating bile acid homeostasis and treatment of bile acid disorders and diseases
EP2938740B1 (en) 2012-12-27 2022-04-20 NGM Biopharmaceuticals, Inc. Chimeric fgf19 peptides for use in treating bile acid disorders
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CN106279437B (zh) 2016-08-19 2017-10-31 安源医药科技（上海）有限公司 高糖基化人凝血因子viii融合蛋白及其制备方法与用途
CN107759696A (zh) 2016-08-19 2018-03-06 安源医药科技（上海）有限公司 人白介素7融合蛋白及其制备方法
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JP7328891B2 (ja) 2016-11-10 2023-08-17 ユーハン・コーポレイション 融合タンパク質を含む、肝炎、肝線維症、および肝硬変を予防または処置するための医薬組成物
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Also Published As

Publication number Publication date
EP2858662A1 (en) 2015-04-15
JP2015527974A (ja) 2015-09-24
MX2014015257A (es) 2015-03-05
PH12014502766A1 (en) 2015-02-09
US8741841B2 (en) 2014-06-03
EP2858662B1 (en) 2017-08-09
HK1203357A1 (en) 2015-10-30
BR112014029966A2 (pt) 2017-09-12
US20140228282A1 (en) 2014-08-14
IL235832A0 (en) 2015-01-29
JP6182600B2 (ja) 2017-08-16
CN104394882A (zh) 2015-03-04
EA201492053A1 (ru) 2015-02-27
KR20150006060A (ko) 2015-01-15
SG11201408095XA (en) 2015-01-29
CO7151525A2 (es) 2014-12-29
TW201408693A (zh) 2014-03-01
AU2013274638A1 (en) 2014-11-06
CN104394882B (zh) 2016-06-22
ES2644787T3 (es) 2017-11-30
IN2014MN02132A (es) 2015-09-11
PE20150201A1 (es) 2015-02-19
WO2013188181A1 (en) 2013-12-19
TN2014000439A1 (en) 2016-03-30
CA2871145A1 (en) 2013-12-19
ECSP14030742A (es) 2015-09-30
US8927492B2 (en) 2015-01-06
US20130330336A1 (en) 2013-12-12
TWI513705B (zh) 2015-12-21
CL2014003078A1 (es) 2015-02-27

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