AR090842A1 - Cuantificacion de impurezas para ensayos de liberacion de productos peptidicos - Google Patents
Cuantificacion de impurezas para ensayos de liberacion de productos peptidicosInfo
- Publication number
- AR090842A1 AR090842A1 ARP130101390A ARP130101390A AR090842A1 AR 090842 A1 AR090842 A1 AR 090842A1 AR P130101390 A ARP130101390 A AR P130101390A AR P130101390 A ARP130101390 A AR P130101390A AR 090842 A1 AR090842 A1 AR 090842A1
- Authority
- AR
- Argentina
- Prior art keywords
- impurities
- quantification
- product release
- release tests
- peptidic product
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6848—Methods of protein analysis involving mass spectrometry
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Hematology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Bioinformatics & Computational Biology (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Food Science & Technology (AREA)
- Cell Biology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Peptides Or Proteins (AREA)
Abstract
Método para la determinación cuantitativa de una impureza presente en un producto peptídico, donde la impureza no se puede separar de otras impurezas del producto principal. El método implica particularmente el uso de la detección por espectrometría de masas de alta resolución (EM) con o sin cromatografía líquida de alta resolución (HPLC). El método se puede utilizar para la investigación de la calidad de péptidos y proteínas, particularmente de péptidos y proteínas farmacéuticas. Kit.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/EP2012/057771 WO2013182217A1 (en) | 2012-04-27 | 2012-04-27 | Quantification of impurities for release testing of peptide products |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR090842A1 true AR090842A1 (es) | 2014-12-10 |
Family
ID=48227257
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP130101390A AR090842A1 (es) | 2012-04-27 | 2013-04-25 | Cuantificacion de impurezas para ensayos de liberacion de productos peptidicos |
Country Status (16)
| Country | Link |
|---|---|
| JP (1) | JP6121522B2 (es) |
| KR (1) | KR102071737B1 (es) |
| CN (1) | CN104246508B (es) |
| AR (1) | AR090842A1 (es) |
| AU (1) | AU2013254728B2 (es) |
| BR (1) | BR112014026613B1 (es) |
| CA (1) | CA2869041C (es) |
| DK (1) | DK2841950T3 (es) |
| EA (1) | EA029893B1 (es) |
| ES (1) | ES2702712T3 (es) |
| HU (1) | HUE042296T2 (es) |
| IL (1) | IL234914A (es) |
| MX (1) | MX353306B (es) |
| SG (1) | SG11201406094XA (es) |
| TW (1) | TWI589874B (es) |
| WO (2) | WO2013182217A1 (es) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UA116217C2 (uk) | 2012-10-09 | 2018-02-26 | Санофі | Пептидна сполука як подвійний агоніст рецепторів glp1-1 та глюкагону |
| AR094180A1 (es) | 2012-12-21 | 2015-07-15 | Sanofi Sa | Derivados de exendina-4 |
| EP3080152A1 (en) | 2013-12-13 | 2016-10-19 | Sanofi | Non-acylated exendin-4 peptide analogues |
| EP3080149A1 (en) | 2013-12-13 | 2016-10-19 | Sanofi | Dual glp-1/glucagon receptor agonists |
| EP3080150B1 (en) | 2013-12-13 | 2018-08-01 | Sanofi | Exendin-4 peptide analogues as dual glp-1/gip receptor agonists |
| WO2015086729A1 (en) | 2013-12-13 | 2015-06-18 | Sanofi | Dual glp-1/gip receptor agonists |
| TW201625669A (zh) | 2014-04-07 | 2016-07-16 | 賽諾菲公司 | 衍生自艾塞那肽－４（Ｅｘｅｎｄｉｎ－４）之肽類雙重ＧＬＰ－１／升糖素受體促效劑 |
| TW201625668A (zh) | 2014-04-07 | 2016-07-16 | 賽諾菲公司 | 作為胜肽性雙重ｇｌｐ－１／昇糖素受體激動劑之艾塞那肽－４衍生物 |
| TW201625670A (zh) | 2014-04-07 | 2016-07-16 | 賽諾菲公司 | 衍生自ｅｘｅｎｄｉｎ－４之雙重ｇｌｐ－１／升糖素受體促效劑 |
| US9932381B2 (en) | 2014-06-18 | 2018-04-03 | Sanofi | Exendin-4 derivatives as selective glucagon receptor agonists |
| CN104211801A (zh) * | 2014-07-25 | 2014-12-17 | 杭州诺泰制药技术有限公司 | 一种制备利西拉来的方法 |
| CN106153748B (zh) * | 2015-03-31 | 2019-02-22 | 深圳翰宇药业股份有限公司 | 一种检测多肽中n,n-二异丙基碳二亚胺的方法 |
| AR105319A1 (es) | 2015-06-05 | 2017-09-27 | Sanofi Sa | Profármacos que comprenden un conjugado agonista dual de glp-1 / glucagón conector ácido hialurónico |
| AR105284A1 (es) | 2015-07-10 | 2017-09-20 | Sanofi Sa | Derivados de exendina-4 como agonistas peptídicos duales específicos de los receptores de glp-1 / glucagón |
| JP6505268B1 (ja) * | 2018-01-11 | 2019-04-24 | 株式会社日立ハイテクサイエンス | 質量分析装置及び質量分析方法 |
| TW202045927A (zh) * | 2019-02-27 | 2020-12-16 | 法商賽諾菲公司 | 以具內標之lc-ms於樣品中進行聚山梨醇酯定量之方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ512663A (en) * | 1999-01-14 | 2004-05-28 | Amylin Pharmaceuticals Inc | Novel exendin agonist formulations and methods of administration thereof |
| US6451611B1 (en) * | 2000-07-28 | 2002-09-17 | Statens Serum Institute | Quantitative analysis of hexose-monophosphates from biological samples |
| US7427675B2 (en) * | 2004-08-23 | 2008-09-23 | Isis Pharmaceuticals, Inc. | Compounds and methods for the characterization of oligonucleotides |
| DE102004043153B4 (de) * | 2004-09-03 | 2013-11-21 | Philipps-Universität Marburg | Erfindung betreffend GLP-1 und Exendin |
| US20130137645A1 (en) * | 2010-07-19 | 2013-05-30 | Mary S. Rosendahl | Modified peptides and proteins |
-
2012
- 2012-04-27 WO PCT/EP2012/057771 patent/WO2013182217A1/en active Application Filing
-
2013
- 2013-04-25 KR KR1020147031124A patent/KR102071737B1/ko active IP Right Grant
- 2013-04-25 JP JP2015507532A patent/JP6121522B2/ja active Active
- 2013-04-25 BR BR112014026613-1A patent/BR112014026613B1/pt active IP Right Grant
- 2013-04-25 MX MX2014012826A patent/MX353306B/es active IP Right Grant
- 2013-04-25 ES ES13719509T patent/ES2702712T3/es active Active
- 2013-04-25 DK DK13719509.5T patent/DK2841950T3/en active
- 2013-04-25 TW TW102114745A patent/TWI589874B/zh active
- 2013-04-25 SG SG11201406094XA patent/SG11201406094XA/en unknown
- 2013-04-25 WO PCT/EP2013/058619 patent/WO2013160397A1/en active Application Filing
- 2013-04-25 AU AU2013254728A patent/AU2013254728B2/en active Active
- 2013-04-25 CN CN201380020553.7A patent/CN104246508B/zh active Active
- 2013-04-25 AR ARP130101390A patent/AR090842A1/es unknown
- 2013-04-25 HU HUE13719509A patent/HUE042296T2/hu unknown
- 2013-04-25 EA EA201491974A patent/EA029893B1/ru not_active IP Right Cessation
- 2013-04-25 CA CA2869041A patent/CA2869041C/en active Active
-
2014
- 2014-09-30 IL IL234914A patent/IL234914A/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| BR112014026613B1 (pt) | 2021-12-21 |
| SG11201406094XA (en) | 2014-10-30 |
| TWI589874B (zh) | 2017-07-01 |
| MX353306B (es) | 2018-01-08 |
| TW201348701A (zh) | 2013-12-01 |
| CA2869041C (en) | 2021-05-04 |
| KR102071737B1 (ko) | 2020-01-30 |
| EA029893B1 (ru) | 2018-05-31 |
| ES2702712T3 (es) | 2019-03-05 |
| WO2013182217A1 (en) | 2013-12-12 |
| WO2013160397A1 (en) | 2013-10-31 |
| HUE042296T2 (hu) | 2019-06-28 |
| DK2841950T3 (en) | 2019-01-14 |
| AU2013254728A1 (en) | 2014-11-20 |
| JP2015515004A (ja) | 2015-05-21 |
| AU2013254728B2 (en) | 2018-04-12 |
| CA2869041A1 (en) | 2013-10-31 |
| MX2014012826A (es) | 2015-11-13 |
| JP6121522B2 (ja) | 2017-04-26 |
| CN104246508A (zh) | 2014-12-24 |
| BR112014026613A2 (pt) | 2017-07-18 |
| KR20150003794A (ko) | 2015-01-09 |
| EA201491974A1 (ru) | 2015-02-27 |
| IL234914A (en) | 2017-12-31 |
| CN104246508B (zh) | 2016-06-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |