CL2017000200A1 - Célula huésped mejorada para producir proteinas - Google Patents

Célula huésped mejorada para producir proteinas

Info

Publication number
CL2017000200A1
CL2017000200A1 CL2017000200A CL2017000200A CL2017000200A1 CL 2017000200 A1 CL2017000200 A1 CL 2017000200A1 CL 2017000200 A CL2017000200 A CL 2017000200A CL 2017000200 A CL2017000200 A CL 2017000200A CL 2017000200 A1 CL2017000200 A1 CL 2017000200A1
Authority
CL
Chile
Prior art keywords
host cell
produce proteins
enhanced host
cell
peptides
Prior art date
Application number
CL2017000200A
Other languages
English (en)
Inventor
Cédric Szpirer
Jonathan Cavrenne
Benjamin Michel
Original Assignee
Delphi Genetics
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Delphi Genetics filed Critical Delphi Genetics
Publication of CL2017000200A1 publication Critical patent/CL2017000200A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/65—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression using markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
    • C12Y207/07—Nucleotidyltransferases (2.7.7)
    • C12Y207/07006—DNA-directed RNA polymerase (2.7.7.6)

Abstract

<p>LA PRESENTE INVENCIÓN SE RELACIONA CON UNA CÉLULA HOSPEDERA PARA PRODUCIR UN PÉPTIDO. POLIPÉPTIDO O PROTEÍNA RECOMBINANTE DE INTERÉS, EN DONDE DICHA CÉLULA HOSPEDERA COMPRENDE AL MENOS 2 COPIAS DE UNA SECUENCIA DE ÁCIDO NUCLÉICO QUE CODIFICA UNA PROTEÍNA VENENO: Y AL USO DE LA MISMA PARA LA PRODUCCIÓN DE PÉPTIDOS, POLIPÉPTIDOS O PROTEÍNAS DE INTERÉS.</p>
CL2017000200A 2014-07-25 2017-01-25 Célula huésped mejorada para producir proteinas CL2017000200A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP14178656 2014-07-25
EP14182341 2014-08-26

Publications (1)

Publication Number Publication Date
CL2017000200A1 true CL2017000200A1 (es) 2017-07-14

Family

ID=53718025

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2017000200A CL2017000200A1 (es) 2014-07-25 2017-01-25 Célula huésped mejorada para producir proteinas

Country Status (10)

Country Link
US (1) US10718001B2 (es)
EP (1) EP3172334B1 (es)
JP (3) JP7126824B2 (es)
CN (1) CN106715681B (es)
AU (1) AU2015293825B2 (es)
BR (1) BR112017001463A2 (es)
CA (1) CA2956107A1 (es)
CL (1) CL2017000200A1 (es)
ES (1) ES2903413T3 (es)
WO (1) WO2016012607A1 (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017147507A1 (en) * 2016-02-24 2017-08-31 Xycrobe Therapeutics, Inc. Skin probiotic formulation
US11180541B2 (en) * 2017-09-28 2021-11-23 Geltor, Inc. Recombinant collagen and elastin molecules and uses thereof
CN110373422B (zh) * 2019-07-12 2022-05-10 扬州大学 重组裂解猪霍乱沙门菌及其构建方法和应用
EP4010500A1 (de) * 2019-08-05 2022-06-15 Wacker Chemie AG Bakterienstamm zur freisetzung eines rekombinanten proteins in einem fermentationsverfahren
CN114540394A (zh) * 2020-11-25 2022-05-27 中国科学院深圳先进技术研究院 一种噬菌体相关的基因诱导表达系统
WO2023069900A1 (en) * 2021-10-18 2023-04-27 Modernatx, Inc. Custom bacterial strain for recombinant protein production

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* Cited by examiner, † Cited by third party
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US4952496A (en) 1984-03-30 1990-08-28 Associated Universities, Inc. Cloning and expression of the gene for bacteriophage T7 RNA polymerase
CA2327387C (en) 1998-05-07 2012-07-03 Gx Biosystems A/S Cytotoxin-based biological containment
US6355412B1 (en) 1999-07-09 2002-03-12 The European Molecular Biology Laboratory Methods and compositions for directed cloning and subcloning using homologous recombination
EP1111061A1 (en) 1999-12-20 2001-06-27 Universite Libre De Bruxelles Double selection vector
WO2002066657A1 (en) * 2001-02-23 2002-08-29 Universite Libre De Bruxelles Method for the selection of recombinant clones comprising a sequence encoding an antidote protein to a toxic molecule
JP4191037B2 (ja) 2001-11-02 2008-12-03 日本テクノ株式会社 滅菌用振動攪拌装置並びに振動攪拌装置を用いる滅菌装置及び滅菌方法
IL164131A0 (en) 2002-03-19 2005-12-18 Univ Bruxelles Poison/antidote genetic systems for the selection of genetically modified eucaryote cells or organisms
CN1703509B (zh) * 2002-09-03 2010-09-01 布鲁塞尔自由大学 可逆的、平行的和多任务的克隆方法和试剂盒
GB0609124D0 (en) * 2006-05-09 2006-06-21 Univ Birmingham Plasmid curing
JP2010187541A (ja) 2007-05-29 2010-09-02 Ajinomoto Co Inc Ｌ−リジンの製造法
CA2730741C (en) 2008-07-18 2016-10-25 Regis Sodoyer Self-replicating vector lacking an antibiotic-resistance gene
JP5729702B2 (ja) 2009-03-23 2015-06-03 国立研究開発法人産業技術総合研究所 コウジ酸の産生に必須の遺伝子を利用してコウジ酸の産生量を向上する方法
JP5918125B2 (ja) * 2009-05-22 2016-05-18 メリアル リミテッド 抗生物質フリープラスミド
EP3385388A1 (en) * 2011-03-22 2018-10-10 OPX Biotechnologies Inc. Microbial production of chemical products and related compositions, methods and systems
US20140147890A1 (en) * 2011-07-07 2014-05-29 Delphi Genetics Genetically modified phage and use thereof
CN103797113B (zh) * 2011-07-07 2018-08-10 德尔菲遗传学公司 遗传修饰的噬菌体及其用途
US9920323B2 (en) * 2011-07-07 2018-03-20 Delphi Genetics Genetically modified phage and use thereof
EP2570134A1 (en) * 2011-09-15 2013-03-20 De la Cueva-Mendez, Guillermo Systems and methods for diminishing cell growth and including selective killing of target cells
JP6279466B2 (ja) 2012-04-27 2018-02-14 Ｊｃｒファーマ株式会社 新規な発現ベクター
DE102012213206A1 (de) * 2012-07-26 2014-01-30 Trumpf Laser- Und Systemtechnik Gmbh Vorrichtung zum Drehen eines Laserbearbeitungskopfes mittels eines Torque-Motors
JP2014057546A (ja) * 2012-09-18 2014-04-03 Osaka Univ トキシン−アンチトキシン系を利用したベクター

Also Published As

Publication number Publication date
JP2020202828A (ja) 2020-12-24
CA2956107A1 (en) 2016-01-28
BR112017001463A2 (pt) 2018-02-20
JP2017523780A (ja) 2017-08-24
AU2015293825A1 (en) 2017-02-16
US10718001B2 (en) 2020-07-21
AU2015293825B2 (en) 2019-06-13
US20170211118A1 (en) 2017-07-27
WO2016012607A1 (en) 2016-01-28
ES2903413T3 (es) 2022-04-01
EP3172334A1 (en) 2017-05-31
EP3172334B1 (en) 2021-11-10
CN106715681A (zh) 2017-05-24
JP7194711B2 (ja) 2022-12-22
JP7126824B2 (ja) 2022-08-29
CN106715681B (zh) 2021-08-24
JP2022162124A (ja) 2022-10-21

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