MX353306B - Cuantificacion de impurezas para ensayos de liberacion de productos peptidicos. - Google Patents

Cuantificacion de impurezas para ensayos de liberacion de productos peptidicos.

Info

Publication number
MX353306B
MX353306B MX2014012826A MX2014012826A MX353306B MX 353306 B MX353306 B MX 353306B MX 2014012826 A MX2014012826 A MX 2014012826A MX 2014012826 A MX2014012826 A MX 2014012826A MX 353306 B MX353306 B MX 353306B
Authority
MX
Mexico
Prior art keywords
impurities
quantification
peptide products
release testing
proteins
Prior art date
Application number
MX2014012826A
Other languages
English (en)
Other versions
MX2014012826A (es
Inventor
Vogel Martin
Mueller Werner
Original Assignee
Sanofi Aventis Deutschland
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis Deutschland filed Critical Sanofi Aventis Deutschland
Publication of MX2014012826A publication Critical patent/MX2014012826A/es
Publication of MX353306B publication Critical patent/MX353306B/es

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848—Methods of protein analysis involving mass spectrometry

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)

Abstract

La presente invención se refiere a un kit de reactivos para determinar la cantidad de impurezas en una composición de producto de Lixisenatida (AVE0010) que comprende: (i) al menos una preparación madre de Di-Ser(33)-AVE0010 (SEC ID NO: 2) (ii) al menos una preparación madre de Di-Ala(35)-AVE0010 (SEC ID NO:3).
MX2014012826A 2012-04-27 2013-04-25 Cuantificacion de impurezas para ensayos de liberacion de productos peptidicos. MX353306B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/EP2012/057771 WO2013182217A1 (en) 2012-04-27 2012-04-27 Quantification of impurities for release testing of peptide products
PCT/EP2013/058619 WO2013160397A1 (en) 2012-04-27 2013-04-25 Quantification of impurities for release testing of peptide products

Publications (2)

Publication Number Publication Date
MX2014012826A MX2014012826A (es) 2015-11-13
MX353306B true MX353306B (es) 2018-01-08

Family

ID=48227257

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2014012826A MX353306B (es) 2012-04-27 2013-04-25 Cuantificacion de impurezas para ensayos de liberacion de productos peptidicos.

Country Status (16)

Country Link
JP (1) JP6121522B2 (es)
KR (1) KR102071737B1 (es)
CN (1) CN104246508B (es)
AR (1) AR090842A1 (es)
AU (1) AU2013254728B2 (es)
BR (1) BR112014026613B1 (es)
CA (1) CA2869041C (es)
DK (1) DK2841950T3 (es)
EA (1) EA029893B1 (es)
ES (1) ES2702712T3 (es)
HU (1) HUE042296T2 (es)
IL (1) IL234914A (es)
MX (1) MX353306B (es)
SG (1) SG11201406094XA (es)
TW (1) TWI589874B (es)
WO (2) WO2013182217A1 (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA116217C2 (uk) 2012-10-09 2018-02-26 Санофі Пептидна сполука як подвійний агоніст рецепторів glp1-1 та глюкагону
JP2016503771A (ja) 2012-12-21 2016-02-08 サノフイ エキセンジン−４誘導体
EP3080150B1 (en) 2013-12-13 2018-08-01 Sanofi Exendin-4 peptide analogues as dual glp-1/gip receptor agonists
EP3080149A1 (en) 2013-12-13 2016-10-19 Sanofi Dual glp-1/glucagon receptor agonists
EP3080154B1 (en) 2013-12-13 2018-02-07 Sanofi Dual glp-1/gip receptor agonists
WO2015086730A1 (en) 2013-12-13 2015-06-18 Sanofi Non-acylated exendin-4 peptide analogues
TW201625668A (zh) 2014-04-07 2016-07-16 賽諾菲公司 作為胜肽性雙重ｇｌｐ－１／昇糖素受體激動劑之艾塞那肽－４衍生物
TW201625669A (zh) 2014-04-07 2016-07-16 賽諾菲公司 衍生自艾塞那肽－４（Ｅｘｅｎｄｉｎ－４）之肽類雙重ＧＬＰ－１／升糖素受體促效劑
TW201625670A (zh) 2014-04-07 2016-07-16 賽諾菲公司 衍生自ｅｘｅｎｄｉｎ－４之雙重ｇｌｐ－１／升糖素受體促效劑
US9932381B2 (en) 2014-06-18 2018-04-03 Sanofi Exendin-4 derivatives as selective glucagon receptor agonists
CN104211801A (zh) * 2014-07-25 2014-12-17 杭州诺泰制药技术有限公司 一种制备利西拉来的方法
CN106153748B (zh) * 2015-03-31 2019-02-22 深圳翰宇药业股份有限公司 一种检测多肽中n,n-二异丙基碳二亚胺的方法
AR105319A1 (es) 2015-06-05 2017-09-27 Sanofi Sa Profármacos que comprenden un conjugado agonista dual de glp-1 / glucagón conector ácido hialurónico
AR105284A1 (es) 2015-07-10 2017-09-20 Sanofi Sa Derivados de exendina-4 como agonistas peptídicos duales específicos de los receptores de glp-1 / glucagón
JP6505268B1 (ja) * 2018-01-11 2019-04-24 株式会社日立ハイテクサイエンス 質量分析装置及び質量分析方法
TW202045927A (zh) * 2019-02-27 2020-12-16 法商賽諾菲公司 以具內標之lc-ms於樣品中進行聚山梨醇酯定量之方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ512663A (en) * 1999-01-14 2004-05-28 Amylin Pharmaceuticals Inc Novel exendin agonist formulations and methods of administration thereof
US6451611B1 (en) * 2000-07-28 2002-09-17 Statens Serum Institute Quantitative analysis of hexose-monophosphates from biological samples
WO2006023880A2 (en) 2004-08-23 2006-03-02 Isis Pharmaceuticals, Inc. Compounds and methods for the characterization of oligonucleotides
DE102004043153B4 (de) * 2004-09-03 2013-11-21 Philipps-Universität Marburg Erfindung betreffend GLP-1 und Exendin
US20130137645A1 (en) * 2010-07-19 2013-05-30 Mary S. Rosendahl Modified peptides and proteins

Also Published As

Publication number Publication date
HUE042296T2 (hu) 2019-06-28
TWI589874B (zh) 2017-07-01
EA201491974A1 (ru) 2015-02-27
CN104246508A (zh) 2014-12-24
BR112014026613A2 (pt) 2017-07-18
KR20150003794A (ko) 2015-01-09
JP6121522B2 (ja) 2017-04-26
TW201348701A (zh) 2013-12-01
CA2869041A1 (en) 2013-10-31
AU2013254728A1 (en) 2014-11-20
IL234914A (en) 2017-12-31
ES2702712T3 (es) 2019-03-05
WO2013182217A1 (en) 2013-12-12
BR112014026613B1 (pt) 2021-12-21
DK2841950T3 (en) 2019-01-14
JP2015515004A (ja) 2015-05-21
EA029893B1 (ru) 2018-05-31
CA2869041C (en) 2021-05-04
KR102071737B1 (ko) 2020-01-30
SG11201406094XA (en) 2014-10-30
AR090842A1 (es) 2014-12-10
WO2013160397A1 (en) 2013-10-31
CN104246508B (zh) 2016-06-08
MX2014012826A (es) 2015-11-13
AU2013254728B2 (en) 2018-04-12

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