AR089838A1 - Derivados de sitaxetan - Google Patents

Derivados de sitaxetan

Info

Publication number
AR089838A1
AR089838A1 ARP130100263A ARP130100263A AR089838A1 AR 089838 A1 AR089838 A1 AR 089838A1 AR P130100263 A ARP130100263 A AR P130100263A AR P130100263 A ARP130100263 A AR P130100263A AR 089838 A1 AR089838 A1 AR 089838A1
Authority
AR
Argentina
Prior art keywords
group
ethyl
methyl
formula
pentafluoroethyl
Prior art date
Application number
ARP130100263A
Other languages
English (en)
Inventor
Tanaka Keigo
Nishioka Tomoki
Original Assignee
Eisai R&D Man Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eisai R&D Man Co Ltd filed Critical Eisai R&D Man Co Ltd
Publication of AR089838A1 publication Critical patent/AR089838A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A61K31/422—Oxazoles not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)

Abstract

Reivindicación 1: Un compuesto representado por la fórmula (1) o la fórmula (2), o una sal farmacológicamente aceptable de este, donde R¹ es un átomo halógeno, un grupo metilo, un grupo etilo, un grupo trifluorometilo, un grupo pentafluoroetilo, un grupo n-propilo o un grupo ciclopropilo; R² es un átomo de hidrógeno, un grupo metilo, un grupo etilo, un grupo trifluorometilo, un grupo pentafluoroetilo, un grupo n-propilo o un grupo ciclopropilo; R³ es un grupo alquilo C₁₋₆ o un grupo alcoxi C₁₋₆; y M es un grupo seleccionado del grupo constituido por el grupo de formulas (3), donde R⁴ es un átomo de hidrógeno, un grupo metilo o un grupo etilo.
ARP130100263A 2012-01-31 2013-01-29 Derivados de sitaxetan AR089838A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201261592923P 2012-01-31 2012-01-31

Publications (1)

Publication Number Publication Date
AR089838A1 true AR089838A1 (es) 2014-09-17

Family

ID=48870751

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP130100263A AR089838A1 (es) 2012-01-31 2013-01-29 Derivados de sitaxetan

Country Status (16)

Country Link
US (1) US8592470B2 (es)
EP (1) EP2810943B1 (es)
JP (1) JP6144631B2 (es)
KR (1) KR101933251B1 (es)
CN (1) CN104039781B (es)
AR (1) AR089838A1 (es)
AU (1) AU2013216122B9 (es)
BR (1) BR112014016204B1 (es)
CA (1) CA2861477C (es)
ES (1) ES2651293T3 (es)
IL (1) IL233171A (es)
IN (1) IN2014CN04945A (es)
MX (1) MX358151B (es)
RU (1) RU2622386C2 (es)
TW (1) TW201336496A (es)
WO (1) WO2013115162A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20240022646A (ko) 2021-06-22 2024-02-20 앨커메디신, 인크. 화합물, 엔도텔린 a 수용체 길항제 및 의약 조성물

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4861366A (en) 1984-08-27 1989-08-29 E. I. Du Pont De Nemours And Company Herbicidal acetals and ketals
US4659369A (en) 1984-08-27 1987-04-21 E. I. Du Pont De Nemours And Company Herbicidal acetals and ketals
US4753672A (en) 1985-07-16 1988-06-28 E. I. Du Pont De Nemours And Company Herbicidal acetals and ketals
TW224462B (es) * 1992-02-24 1994-06-01 Squibb & Sons Inc
CZ299246B6 (cs) * 1995-04-04 2008-05-28 Encysive Pharmaceuticals Inc. Sulfonamid, farmaceutická kompozice s jeho obsahem a jeho použití pro výrobu léciva
AU2464301A (en) * 1999-12-31 2001-07-16 Encysive Pharmaceuticals Inc. Sulfonamides and derivatives thereof that modulate the activity of endothelin
US20060205733A1 (en) * 2004-08-26 2006-09-14 Encysive Pharmaceuticals Endothelin a receptor antagonists in combination with phosphodiesterase 5 inhibitors and uses thereof
JP2009184924A (ja) 2006-05-31 2009-08-20 Eisai R & D Management Co Ltd 生物学的試薬用化合物
US7863308B2 (en) * 2007-04-10 2011-01-04 Auspex Pharmaceuticals, Inc. Substituted thiophenes

Also Published As

Publication number Publication date
JPWO2013115162A1 (ja) 2015-05-11
KR20140117455A (ko) 2014-10-07
CA2861477A1 (en) 2013-08-08
TW201336496A (zh) 2013-09-16
MX358151B (es) 2018-08-07
BR112014016204B1 (pt) 2020-09-24
US8592470B2 (en) 2013-11-26
CN104039781B (zh) 2016-08-17
KR101933251B1 (ko) 2018-12-27
ES2651293T3 (es) 2018-01-25
IN2014CN04945A (es) 2015-09-18
IL233171A0 (en) 2014-07-31
MX2014007619A (es) 2014-09-15
CN104039781A (zh) 2014-09-10
EP2810943A4 (en) 2015-09-02
AU2013216122B9 (en) 2017-02-02
CA2861477C (en) 2018-01-02
JP6144631B2 (ja) 2017-06-07
WO2013115162A1 (ja) 2013-08-08
EP2810943B1 (en) 2017-09-27
BR112014016204A2 (pt) 2017-06-13
EP2810943A1 (en) 2014-12-10
US20130197045A1 (en) 2013-08-01
IL233171A (en) 2017-07-31
RU2014126427A (ru) 2016-03-20
AU2013216122B2 (en) 2016-12-08
RU2622386C2 (ru) 2017-06-15
AU2013216122A1 (en) 2014-07-24
BR112014016204A8 (pt) 2017-07-04

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