IN2014CN04945A - - Google Patents
Info
- Publication number
- IN2014CN04945A IN2014CN04945A IN4945CHN2014A IN2014CN04945A IN 2014CN04945 A IN2014CN04945 A IN 2014CN04945A IN 4945CHN2014 A IN4945CHN2014 A IN 4945CHN2014A IN 2014CN04945 A IN2014CN04945 A IN 2014CN04945A
- Authority
- IN
- India
- Prior art keywords
- formula
- sitaxsentan
- retains
- formulas
- represented
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/422—Oxazoles not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Epidemiology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Steroid Compounds (AREA)
Abstract
1231 6A compound represented by formula (1 1) or (1 2) or a pharmaceutically acceptable salt thereof retains the main beneficial effects of sitaxsentan while having an improved CYP inhibitory action. [In the formulas R is a halogen atom etc. R is a methyl group etc. R is a C alkyl group etc. and M is a group represented by formula AA etc.]
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261592923P | 2012-01-31 | 2012-01-31 | |
| PCT/JP2013/051857 WO2013115162A1 (en) | 2012-01-31 | 2013-01-29 | Sitaxsentan derivative |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2014CN04945A true IN2014CN04945A (en) | 2015-09-18 |
Family
ID=48870751
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN4945CHN2014 IN2014CN04945A (en) | 2012-01-31 | 2013-01-29 |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US8592470B2 (en) |
| EP (1) | EP2810943B1 (en) |
| JP (1) | JP6144631B2 (en) |
| KR (1) | KR101933251B1 (en) |
| CN (1) | CN104039781B (en) |
| AR (1) | AR089838A1 (en) |
| AU (1) | AU2013216122B9 (en) |
| BR (1) | BR112014016204B1 (en) |
| CA (1) | CA2861477C (en) |
| ES (1) | ES2651293T3 (en) |
| IL (1) | IL233171A (en) |
| IN (1) | IN2014CN04945A (en) |
| MX (1) | MX358151B (en) |
| RU (1) | RU2622386C2 (en) |
| TW (1) | TW201336496A (en) |
| WO (1) | WO2013115162A1 (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7531947B2 (en) | 2021-06-22 | 2024-08-13 | 株式会社アークメディスン | Compound, endothelin A receptor antagonist and pharmaceutical composition |
| TW202423432A (en) * | 2022-11-11 | 2024-06-16 | 日商亞克醫藥股份有限公司 | Compound, endothelin a receptor antagonist, angiotensin ii type 1 receptor antagonist and pharmaceutical composition |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4861366A (en) | 1984-08-27 | 1989-08-29 | E. I. Du Pont De Nemours And Company | Herbicidal acetals and ketals |
| US4659369A (en) | 1984-08-27 | 1987-04-21 | E. I. Du Pont De Nemours And Company | Herbicidal acetals and ketals |
| US4753672A (en) | 1985-07-16 | 1988-06-28 | E. I. Du Pont De Nemours And Company | Herbicidal acetals and ketals |
| TW224462B (en) * | 1992-02-24 | 1994-06-01 | Squibb & Sons Inc | |
| JP3233642B2 (en) * | 1995-04-04 | 2001-11-26 | テキサス・バイオテクノロジー・コーポレイシヨン | Thienyl-, furyl-, pyrrolyl- and biphenylsulfonamides and their derivatives for regulating the activity of endothelin |
| PL197782B1 (en) * | 1999-12-31 | 2008-04-30 | Encysive Pharmaceuticals Inc | Sulfonamides and derivatives thereof that modulate the activity of endothelin |
| US20060205733A1 (en) * | 2004-08-26 | 2006-09-14 | Encysive Pharmaceuticals | Endothelin a receptor antagonists in combination with phosphodiesterase 5 inhibitors and uses thereof |
| JP2009184924A (en) | 2006-05-31 | 2009-08-20 | Eisai R & D Management Co Ltd | Compound for biological reagent |
| JP2010523694A (en) * | 2007-04-10 | 2010-07-15 | オースペックス・ファーマシューティカルズ・インコーポレイテッド | Substituted deuterium enriched thiophene for the treatment of hypertension |
-
2013
- 2013-01-29 CA CA2861477A patent/CA2861477C/en active Active
- 2013-01-29 EP EP13743422.1A patent/EP2810943B1/en active Active
- 2013-01-29 RU RU2014126427A patent/RU2622386C2/en active
- 2013-01-29 CN CN201380005150.5A patent/CN104039781B/en active Active
- 2013-01-29 AR ARP130100263A patent/AR089838A1/en unknown
- 2013-01-29 JP JP2013556399A patent/JP6144631B2/en active Active
- 2013-01-29 TW TW102103329A patent/TW201336496A/en unknown
- 2013-01-29 BR BR112014016204-2A patent/BR112014016204B1/en active IP Right Grant
- 2013-01-29 AU AU2013216122A patent/AU2013216122B9/en not_active Ceased
- 2013-01-29 KR KR1020147021115A patent/KR101933251B1/en active IP Right Grant
- 2013-01-29 MX MX2014007619A patent/MX358151B/en active IP Right Grant
- 2013-01-29 US US13/752,660 patent/US8592470B2/en active Active
- 2013-01-29 IN IN4945CHN2014 patent/IN2014CN04945A/en unknown
- 2013-01-29 WO PCT/JP2013/051857 patent/WO2013115162A1/en active Application Filing
- 2013-01-29 ES ES13743422.1T patent/ES2651293T3/en active Active
-
2014
- 2014-06-16 IL IL233171A patent/IL233171A/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| CA2861477A1 (en) | 2013-08-08 |
| CA2861477C (en) | 2018-01-02 |
| CN104039781B (en) | 2016-08-17 |
| CN104039781A (en) | 2014-09-10 |
| US8592470B2 (en) | 2013-11-26 |
| MX2014007619A (en) | 2014-09-15 |
| JPWO2013115162A1 (en) | 2015-05-11 |
| AU2013216122B2 (en) | 2016-12-08 |
| US20130197045A1 (en) | 2013-08-01 |
| KR101933251B1 (en) | 2018-12-27 |
| KR20140117455A (en) | 2014-10-07 |
| BR112014016204B1 (en) | 2020-09-24 |
| ES2651293T3 (en) | 2018-01-25 |
| AR089838A1 (en) | 2014-09-17 |
| MX358151B (en) | 2018-08-07 |
| JP6144631B2 (en) | 2017-06-07 |
| EP2810943B1 (en) | 2017-09-27 |
| BR112014016204A2 (en) | 2017-06-13 |
| EP2810943A4 (en) | 2015-09-02 |
| IL233171A0 (en) | 2014-07-31 |
| RU2014126427A (en) | 2016-03-20 |
| EP2810943A1 (en) | 2014-12-10 |
| AU2013216122A1 (en) | 2014-07-24 |
| BR112014016204A8 (en) | 2017-07-04 |
| IL233171A (en) | 2017-07-31 |
| RU2622386C2 (en) | 2017-06-15 |
| AU2013216122B9 (en) | 2017-02-02 |
| WO2013115162A1 (en) | 2013-08-08 |
| TW201336496A (en) | 2013-09-16 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CA2875877C (en) | Syk inhibitors | |
| PH12014501719A1 (en) | Pyridone derivatives | |
| MY180083A (en) | Tetrahydropyrrolothiazine compounds | |
| PH12016500169A1 (en) | Polymorph of syk inhibitors | |
| RS54526B1 (en) | Pyrazolospiroketone derivatives for use as acetyl-coa carboxylase inhibitors | |
| MX2016006336A (en) | Pyrazolopyrimidine compounds. | |
| RS53301B (en) | Thioacetate compounds, compositions and methods of use | |
| AU2012214029A8 (en) | Rorgammat inhibitors | |
| MX2017010735A (en) | Tgf-p inhibitors. | |
| IN2014MN01897A (en) | ||
| AU2012313888A8 (en) | 3-pyrimidin-4-yl-oxazolidin-2-ones as inhibitors of mutant IDH | |
| PH12016500148A1 (en) | Plant disease control composition and its use | |
| MA40171A (en) | Azamophinan derivatives and use thereof | |
| IN2014DN07509A (en) | ||
| MX2014002833A (en) | Fungicidal 4-substituted-3-{phenyl[(heterocyclylmethoxy)imino]met hyl}-1,2,4-oxadizol-5(4h)-one derivatives. | |
| RS54730B1 (en) | Inhibitors of beta-secretase | |
| MA40170A (en) | Heterocyclic morphinan derivatives and use thereof | |
| MX2017000330A (en) | Pyridone derivative having tetrahydropyranyl methyl group. | |
| IN2014CN04204A (en) | ||
| MA39866A (en) | 2-AMINO-6-METHYL-4,4a,5,6-TETRAHYDROPYRANO[3,4-d][1,3]THIAZIN-8a(8H)-YL-1,3-THIAZOL-4-YL AMIDES | |
| SA517381678B1 (en) | Dihydropyrimidin-2-One Compounds and Medical Use Thereof | |
| PH12015502429A1 (en) | Dicarboxylic acid compound | |
| MY185971A (en) | Pyranodipyridine compound | |
| IN2013CN01335A (en) | ||
| NZ605804A (en) | New aminopyrazoloquinazolines |