AR087142A1 - Metodo para la elaboracion de naltrexona - Google Patents

Metodo para la elaboracion de naltrexona

Info

Publication number
AR087142A1
AR087142A1 ARP110104090A ARP110104090A AR087142A1 AR 087142 A1 AR087142 A1 AR 087142A1 AR P110104090 A ARP110104090 A AR P110104090A AR P110104090 A ARP110104090 A AR P110104090A AR 087142 A1 AR087142 A1 AR 087142A1
Authority
AR
Argentina
Prior art keywords
naltrexone
elaboration
morphinan
dihydroxy
epoxy
Prior art date
Application number
ARP110104090A
Other languages
English (en)
Spanish (es)
Original Assignee
Lundbeck & Co As H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lundbeck & Co As H filed Critical Lundbeck & Co As H
Publication of AR087142A1 publication Critical patent/AR087142A1/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D489/00Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/06Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with a hetero atom directly attached in position 14
    • C07D489/08Oxygen atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/485Morphinan derivatives, e.g. morphine, codeine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrrole Compounds (AREA)
ARP110104090A 2010-11-05 2011-11-03 Metodo para la elaboracion de naltrexona AR087142A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA201001007 2010-11-05
DKPA201100396 2011-05-25

Publications (1)

Publication Number Publication Date
AR087142A1 true AR087142A1 (es) 2014-02-26

Family

ID=46552826

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP110104090A AR087142A1 (es) 2010-11-05 2011-11-03 Metodo para la elaboracion de naltrexona

Country Status (12)

Country Link
KR (1) KR101837795B1 (zh)
CN (1) CN103237804B (zh)
AR (1) AR087142A1 (zh)
BR (1) BR112013009407B8 (zh)
CL (1) CL2013001251A1 (zh)
CO (1) CO6700868A2 (zh)
IL (1) IL225790A (zh)
JO (1) JO3209B1 (zh)
PE (2) PE20171309A1 (zh)
SG (1) SG189369A1 (zh)
TW (1) TWI516491B (zh)
ZA (1) ZA201303224B (zh)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2129395T3 (es) * 1989-10-16 1999-06-16 Us Health Sintesis total de enantiomeros de nortebaina, normorfina, noroximorfona y sus derivados a traves de productos intermedios n-nor.
UA87884C2 (uk) * 2004-12-03 2009-08-25 Мерк Энд Ко., Инк. Безводна кристалічна калієва сіль інгібітора віл-інтегрази
FR2906252B1 (fr) * 2006-09-21 2008-11-28 Sanofi Aventis Sa Procede de preparation d'halogenures de n-aklyl naltrexone
WO2008138383A1 (de) * 2007-05-16 2008-11-20 Cilag Ag Verfahren zur herstellung von n-methylnaltrexonbromid
ES2566559T3 (es) * 2008-09-30 2016-04-13 Mallinckrodt Llc Procesos para la alquilación de grupos amino secundarios de derivados de morfinano

Also Published As

Publication number Publication date
BR112013009407B8 (pt) 2022-11-22
KR101837795B1 (ko) 2018-03-12
CO6700868A2 (es) 2013-06-28
JO3209B1 (ar) 2018-03-08
CL2013001251A1 (es) 2013-08-30
BR112013009407A2 (pt) 2016-07-19
BR112013009407B1 (pt) 2021-07-20
IL225790A (en) 2016-07-31
IL225790A0 (en) 2013-06-27
TW201219396A (en) 2012-05-16
ZA201303224B (en) 2014-07-30
CN103237804B (zh) 2016-06-08
PE20171309A1 (es) 2017-09-05
CN103237804A (zh) 2013-08-07
SG189369A1 (en) 2013-05-31
TWI516491B (zh) 2016-01-11
KR20130129928A (ko) 2013-11-29
PE20140357A1 (es) 2014-03-29

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