IL225790A0 - Method for the manufacturing of naltrexone - Google Patents
Method for the manufacturing of naltrexoneInfo
- Publication number
- IL225790A0 IL225790A0 IL225790A IL22579013A IL225790A0 IL 225790 A0 IL225790 A0 IL 225790A0 IL 225790 A IL225790 A IL 225790A IL 22579013 A IL22579013 A IL 22579013A IL 225790 A0 IL225790 A0 IL 225790A0
- Authority
- IL
- Israel
- Prior art keywords
- naltrexone
- manufacturing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
- C07D489/06—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with a hetero atom directly attached in position 14
- C07D489/08—Oxygen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Emergency Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DKPA201001007 | 2010-11-05 | ||
DKPA201100396 | 2011-05-25 | ||
PCT/DK2011/000128 WO2012059103A1 (en) | 2010-11-05 | 2011-11-04 | Method for the manufacturing of naltrexone |
Publications (2)
Publication Number | Publication Date |
---|---|
IL225790A0 true IL225790A0 (en) | 2013-06-27 |
IL225790A IL225790A (en) | 2016-07-31 |
Family
ID=46552826
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL225790A IL225790A (en) | 2010-11-05 | 2013-04-17 | Process for the manufacture of naltrexone by reacting noroxymorphone with cyclopropylmethyl halide in the presence of n-ethyl-2-pyrrolidone |
Country Status (12)
Country | Link |
---|---|
KR (1) | KR101837795B1 (en) |
CN (1) | CN103237804B (en) |
AR (1) | AR087142A1 (en) |
BR (1) | BR112013009407B8 (en) |
CL (1) | CL2013001251A1 (en) |
CO (1) | CO6700868A2 (en) |
IL (1) | IL225790A (en) |
JO (1) | JO3209B1 (en) |
PE (2) | PE20140357A1 (en) |
SG (1) | SG189369A1 (en) |
TW (1) | TWI516491B (en) |
ZA (1) | ZA201303224B (en) |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1991005768A1 (en) * | 1989-10-16 | 1991-05-02 | The United States Of America, Represented By The Secretary, United States Department Of Commerce | Total synthesis of northebaine, normorphine, noroxymorphone enantiomers and derivatives via n-nor intermediates |
UA87884C2 (en) * | 2004-12-03 | 2009-08-25 | Мерк Энд Ко., Инк. | Potassium salt of an hiv integrase inhibitor |
FR2906252B1 (en) * | 2006-09-21 | 2008-11-28 | Sanofi Aventis Sa | PROCESS FOR THE PREPARATION OF NALTREXONE N-AKLYL HALIDES |
WO2008138383A1 (en) * | 2007-05-16 | 2008-11-20 | Cilag Ag | Method for the production of n-methyl naltrexone bromide |
US8080661B2 (en) * | 2008-09-30 | 2011-12-20 | Mallinckrodt Llc | Processes for the synthesis of tertiary amines |
-
2011
- 2011-10-31 JO JOP/2011/0328A patent/JO3209B1/en active
- 2011-11-01 TW TW100139692A patent/TWI516491B/en not_active IP Right Cessation
- 2011-11-03 AR ARP110104090A patent/AR087142A1/en unknown
- 2011-11-04 PE PE2013000948A patent/PE20140357A1/en not_active Application Discontinuation
- 2011-11-04 CN CN201180053349.6A patent/CN103237804B/en active Active
- 2011-11-04 PE PE2017001285A patent/PE20171309A1/en not_active Application Discontinuation
- 2011-11-04 KR KR1020137011320A patent/KR101837795B1/en active IP Right Grant
- 2011-11-04 BR BR112013009407A patent/BR112013009407B8/en active IP Right Grant
- 2011-11-04 SG SG2013027412A patent/SG189369A1/en unknown
-
2013
- 2013-04-17 IL IL225790A patent/IL225790A/en active IP Right Grant
- 2013-05-03 CO CO13111250A patent/CO6700868A2/en active IP Right Grant
- 2013-05-03 ZA ZA2013/03224A patent/ZA201303224B/en unknown
- 2013-05-06 CL CL2013001251A patent/CL2013001251A1/en unknown
Also Published As
Publication number | Publication date |
---|---|
BR112013009407A2 (en) | 2016-07-19 |
CO6700868A2 (en) | 2013-06-28 |
CL2013001251A1 (en) | 2013-08-30 |
TWI516491B (en) | 2016-01-11 |
PE20140357A1 (en) | 2014-03-29 |
CN103237804A (en) | 2013-08-07 |
BR112013009407B8 (en) | 2022-11-22 |
PE20171309A1 (en) | 2017-09-05 |
CN103237804B (en) | 2016-06-08 |
KR101837795B1 (en) | 2018-03-12 |
IL225790A (en) | 2016-07-31 |
KR20130129928A (en) | 2013-11-29 |
JO3209B1 (en) | 2018-03-08 |
AR087142A1 (en) | 2014-02-26 |
ZA201303224B (en) | 2014-07-30 |
SG189369A1 (en) | 2013-05-31 |
BR112013009407B1 (en) | 2021-07-20 |
TW201219396A (en) | 2012-05-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FF | Patent granted | ||
KB | Patent renewed | ||
KB | Patent renewed |