AR084229A2 - Preparado polifasico para la contracepcion a base de un estrogeno natural - Google Patents
Preparado polifasico para la contracepcion a base de un estrogeno naturalInfo
- Publication number
- AR084229A2 AR084229A2 ARP110104615A ARP110104615A AR084229A2 AR 084229 A2 AR084229 A2 AR 084229A2 AR P110104615 A ARP110104615 A AR P110104615A AR P110104615 A ARP110104615 A AR P110104615A AR 084229 A2 AR084229 A2 AR 084229A2
- Authority
- AR
- Argentina
- Prior art keywords
- units
- daily doses
- estradiolvalerate
- dose
- polyphasic
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Endocrinology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Reproductive Health (AREA)
- Gynecology & Obstetrics (AREA)
- Diabetes (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Orthopedics, Nursing, And Contraception (AREA)
- Steroid Compounds (AREA)
- Compositions Of Macromolecular Compounds (AREA)
Abstract
Reivindicación 1: Preparado polifásico para la contracepción caracterizado porque la primera fase consiste en 2 unidades de dosis diarias del estrógeno natural, estradiolvalerato, de 3 mg cada una; la segunda fase consiste en 2 grupos de unidades de dosis diarias donde el primer grupo consiste en 5 unidades de dosis diarias de una combinación de 2 mg de estradiolvalerato y por lo menos el doble o el triple de la dosis anovulatoria de un gestágeno sintético, y el segundo grupo consiste en 17 unidades de dosis diarias de una combinación de 2 mg de estradiolvalerato y por lo menos el triple o el cuádruple de la dosis anovulatoria de un gestágeno sintético; una tercera fase de 2 unidades de dosis diarias que contienen 1 mg de estradiolvalerato cada una; y otra fase consistente en 2 unidades de dosis diarias de un placebo farmacéuticamente inocuo.Reivindicación 2: Preparado polifásico de acuerdo con la reivindicación 1, caracterizado porque la sustancia activa gestágena es dienogest, drospirenona o un gestágeno con por lo menos el doble de su dosis anovulatoria conocida.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE102004019743A DE102004019743B4 (de) | 2004-04-20 | 2004-04-20 | Mehrphasenpräparat zur Kontrazeption auf der Basis eines natürlichen Estrogens |
Publications (1)
Publication Number | Publication Date |
---|---|
AR084229A2 true AR084229A2 (es) | 2013-05-02 |
Family
ID=34979546
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP050101553A AR048830A1 (es) | 2004-04-20 | 2005-04-20 | Preparado polifasico para la contracepcion a base de un estrogeno natural y un gestageno sintetico |
ARP110104615A AR084229A2 (es) | 2004-04-20 | 2011-12-12 | Preparado polifasico para la contracepcion a base de un estrogeno natural |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP050101553A AR048830A1 (es) | 2004-04-20 | 2005-04-20 | Preparado polifasico para la contracepcion a base de un estrogeno natural y un gestageno sintetico |
Country Status (38)
Country | Link |
---|---|
US (3) | US8071577B2 (es) |
EP (1) | EP1740163B2 (es) |
JP (1) | JP4908399B2 (es) |
KR (1) | KR20060134168A (es) |
CN (1) | CN1946383B (es) |
AR (2) | AR048830A1 (es) |
AT (1) | ATE473734T1 (es) |
AU (1) | AU2005235418C1 (es) |
BR (1) | BRPI0510005A (es) |
CA (1) | CA2561839C (es) |
CR (1) | CR8695A (es) |
CY (1) | CY1111292T1 (es) |
DE (2) | DE102004019743B4 (es) |
DK (1) | DK1740163T4 (es) |
EA (1) | EA010313B1 (es) |
EC (1) | ECSP067000A (es) |
ES (1) | ES2348038T5 (es) |
GT (1) | GT200500093A (es) |
HK (1) | HK1099701A1 (es) |
HR (1) | HRP20100513T4 (es) |
IL (2) | IL178510A (es) |
ME (1) | ME01183B (es) |
MX (1) | MXPA06012213A (es) |
MY (1) | MY143669A (es) |
NO (1) | NO344098B1 (es) |
NZ (1) | NZ550417A (es) |
PA (1) | PA8630901A1 (es) |
PE (1) | PE20060308A1 (es) |
PL (1) | PL1740163T5 (es) |
PT (1) | PT1740163E (es) |
RS (1) | RS51434B2 (es) |
SI (1) | SI1740163T2 (es) |
SV (1) | SV2006002090A (es) |
TW (1) | TWI351960B (es) |
UA (1) | UA83915C2 (es) |
UY (1) | UY28863A1 (es) |
WO (1) | WO2005102247A2 (es) |
ZA (1) | ZA200609594B (es) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE102004019743B4 (de) | 2004-04-20 | 2008-11-27 | Bayer Schering Pharma Aktiengesellschaft | Mehrphasenpräparat zur Kontrazeption auf der Basis eines natürlichen Estrogens |
EP1937274B1 (de) * | 2005-10-13 | 2012-02-22 | Bayer Pharma Aktiengesellschaft | Verwendung von estradiolvalerat in kombination mit dienogest zur oralen therapie der dysf unktionellen uterinen blutung in einheit mit einer oralen kontrazeption |
PT1787649E (pt) * | 2005-10-13 | 2009-05-08 | Bayer Schering Pharma Ag | Utilização de valerato de estradiol em combinação com dienogest para a terapia oral da hemorragia uterina disfuncional em conjunto com uma contracepção oral |
US8153616B2 (en) * | 2005-10-17 | 2012-04-10 | Bayer Pharma Aktiengesellschaft | Combination preparation for oral contraception and oral therapy of dysfunctional uterine bleeding containing estradiol valerate and dienogest and method of using same |
US8063030B2 (en) | 2006-03-02 | 2011-11-22 | Warner Chilcott Company, Llc | Extended cycle multiphasic oral contraceptive method |
DE102006010329A1 (de) * | 2006-03-06 | 2007-09-13 | Höltge, Michael, Dipl.-Med. | Hormonelles Kontrazeptivum auf der Basis eines Estrogens, eines Gestagens oder einer Kombination von Estrogenen und Gestagenen unter der Zugabe von Testosteron |
EP1930010A1 (de) * | 2006-10-20 | 2008-06-11 | Bayer Schering Pharma Aktiengesellschaft | Verwendung von Estradiolvalerat oder 17ß-Estradiol in Kombination mit Dienogest zur oralen Therapie für den Erhalt und/oder die Steigerung der weiblichen Libido |
US20090117184A1 (en) * | 2007-11-05 | 2009-05-07 | Sabine Fricke | Use of a gestagen in combination with an estrogen and one or more pharmaceutically acceptable auxiliary agents/excipients for lactose-free oral contraception |
AR086395A1 (es) * | 2011-05-11 | 2013-12-11 | Kirax Corp | Envase para el tratamiento de patologias |
Family Cites Families (52)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU4168068A (en) | 1969-07-22 | 1971-01-28 | Unisearch Limited | Improvements in or relating to oral contraceptives |
US3639600A (en) | 1969-08-28 | 1972-02-01 | Upjohn Co | Process of establishing cyclicity in a human female |
US3795734A (en) | 1970-04-20 | 1974-03-05 | American Home Prod | Cyclic regimen of hormone administration for contraception |
US4066757A (en) | 1973-03-26 | 1978-01-03 | Ortho Pharmaceutical Corporation | Oral contraceptive regimen |
DE2365103C3 (de) | 1973-12-21 | 1980-08-28 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | V erwendung von Hormonen zur Kontrazeption |
DE2431704A1 (de) | 1974-07-02 | 1976-01-22 | Asche Ag | Stufenkombinationspraeparate per kontrazeption |
DE2645307A1 (de) | 1976-10-05 | 1978-04-06 | Schering Ag | Neue mittel und neue methoden zur behandlung klimakterischer ausfallerscheinungen |
JPS6019734B2 (ja) | 1977-05-12 | 1985-05-17 | 三共株式会社 | 安定なプロスタグランジンe類製剤の製法 |
US4272270A (en) | 1979-04-04 | 1981-06-09 | Petrochem Consultants, Inc. | Cryogenic recovery of liquid hydrocarbons from hydrogen-rich |
NL8001593A (nl) * | 1980-03-18 | 1981-10-16 | Akzo Nv | Meerfasisch combinatiepreparaat voor orale anticonceptie. |
US4390531A (en) | 1981-08-10 | 1983-06-28 | Syntex Pharmaceuticals International Ltd. | Method of contraception using peak progestogen dosage |
US4921843A (en) | 1988-10-20 | 1990-05-01 | Pasquale Samuel A | Contraception system and method |
US4628051A (en) | 1983-09-26 | 1986-12-09 | Ortho Pharmaceutical Corporation | Triphasic oral contraceptive |
US4530839A (en) | 1983-09-26 | 1985-07-23 | Ortho Pharmaceutical Corporation | Triphasic oral contraceptive |
US4616006A (en) | 1983-09-26 | 1986-10-07 | Ortho Pharmaceutical Corporation | Triphasic oral contraceptive |
US4544554A (en) | 1983-09-26 | 1985-10-01 | Ortho Pharmaceutical Corporation | Triphasic oral contraceptive |
DE3341638A1 (de) | 1983-11-17 | 1984-05-03 | Hermann Dr.rer.nat. 8000 München Heßlinger | Dreiphasen-praeparat zur empfaengnisverhuetung aus ethinyloestradiol und lynestrenol |
DE3347125A1 (de) | 1983-12-22 | 1985-07-11 | Schering AG, 1000 Berlin und 4709 Bergkamen | Mehrstufenkombinationspraeparat und seine verwendung zur oralen kontrazeption |
AU581486B2 (en) | 1985-12-30 | 1989-02-23 | Warner-Lambert Company | Graduated estrogen contraceptive |
IE61236B1 (en) | 1986-07-15 | 1994-10-19 | American Home Prod | Combination dosage form for pre-menopausal women |
CA2005933A1 (en) | 1989-01-09 | 1990-07-09 | Jesse Hipps, Sr. | Photohardenable composition containing five member aromatic group with imine moiety |
IE71203B1 (en) * | 1990-12-13 | 1997-02-12 | Akzo Nv | Low estrogen oral contraceptives |
DE4104385C1 (es) | 1991-02-09 | 1992-08-13 | Marika Dr.Med. 6509 Framersheim De Ehrlich | |
DE4224534A1 (de) | 1992-07-24 | 1994-01-27 | Marika Dr Med Ehrlich | Ovulationshemmendes Mittel zur hormonalen Kontrazeption |
DE4308406C1 (de) | 1993-03-12 | 1994-06-16 | Jenapharm Gmbh | Kombinationspräparat zur Kontrazeption |
DE4313926A1 (de) * | 1993-04-28 | 1994-11-03 | Jenapharm Gmbh | Pharmazeutisches Mehrphasenpräparat zur hormonalen Kontrazeption |
DE4339934C2 (de) | 1993-05-07 | 1995-05-24 | Klaus Dr Med Umbreit | Ovulationshemmendes Mittel zur hormonalen Kontrazeption |
NL9301562A (nl) | 1993-09-09 | 1995-04-03 | Saturnus Ag | Preparaat voor substitutietherapie. |
DE4344462C2 (de) | 1993-12-22 | 1996-02-01 | Schering Ag | Zusammensetzung für die Empfängnisverhütung |
DE4429374C1 (de) | 1994-08-12 | 1996-02-01 | Jenapharm Gmbh | Pharmazeutische Präparate zur Kontrazeption/Hormonsubstitution mit biogener Estrogenkomponente |
DE19525017A1 (de) * | 1995-06-28 | 1997-01-02 | Schering Ag | Pharmazeutisches Kombinatonspräparat, Kit und Methode zur hormonalen Kontrazeption |
DE19540253C2 (de) * | 1995-10-28 | 1998-06-04 | Jenapharm Gmbh | Mehrphasenpräparat zur Kontrazeption auf der Basis natürlicher Estrogene |
US20050032756A1 (en) | 1995-10-28 | 2005-02-10 | Michael Dittgen | Multistage preparation for contraception based on natural estrogens |
EP0917466B1 (en) | 1996-07-26 | 2004-10-06 | Wyeth | Oral contraceptive |
CN1186023C (zh) * | 1996-07-26 | 2005-01-26 | 惠氏公司 | 双相避孕方法及包含孕激素和雌激素组合物的药剂盒 |
ES2223081T3 (es) | 1996-07-26 | 2005-02-16 | Wyeth | Metodo anticonceptivo oral monofasico y kit que comprende una combinacion de progestina y estrogeno. |
US6987101B1 (en) | 1996-12-20 | 2006-01-17 | Schering Aktiengesellschaft | Therapeutic gestagens for the treatment of premenstrual dysphoric disorder |
DE19654609A1 (de) | 1996-12-20 | 1998-06-25 | Schering Ag | Therapeutische Gestagene zur Behandlung von Premenstrual Dysphoric Disorder |
US5898032A (en) | 1997-06-23 | 1999-04-27 | Medical College Of Hampton Roads | Ultra low dose oral contraceptives with less menstrual bleeding and sustained efficacy |
US6312772B1 (en) * | 1997-10-20 | 2001-11-06 | Hoechst Celanese Corporation | Multilayer laminate formed from a substantially stretched non-molten wholly aromatic liquid crystalline polymer and non-polyester thermoplastic polymer |
DE19908762A1 (de) * | 1999-02-18 | 2000-08-31 | Jenapharm Gmbh | Verwendung von Dienogest in hoher Dosierung |
DE10045380A1 (de) | 2000-09-14 | 2002-04-04 | Schering Ag | Verfahren zur Kontrazeption und dessen Darreichungsform |
US6699820B2 (en) | 2001-03-02 | 2004-03-02 | Hartmut Ulrich Bielefeldt | Method for making a superconductor with enhanced current carrying capability |
DE10294402D2 (de) | 2001-09-29 | 2004-11-11 | Solvay Pharm Gmbh | Estrogen-Gestagen Kombinationspräparat und Anwendung |
EP1462106A1 (en) | 2003-03-28 | 2004-09-29 | Pantarhei Bioscience B.V. | Pharmaceutical compositions and kits comprising 17-beta-estradiol and a progesteron for the treatment of gynecological disorders |
JP2007528358A (ja) * | 2003-06-25 | 2007-10-11 | バイエル・シエーリング・ファーマ アクチエンゲゼルシャフト | ジエノゲストを含んでなるホルモン置換療法および抑鬱療法 |
DE102004019743B4 (de) | 2004-04-20 | 2008-11-27 | Bayer Schering Pharma Aktiengesellschaft | Mehrphasenpräparat zur Kontrazeption auf der Basis eines natürlichen Estrogens |
BRPI0516247A (pt) | 2004-10-07 | 2008-08-26 | Duramed Pharmaceuticals Inc | métodos de tratamento hormonal, utilizando regimes de ciclo prolongado de dose crescente |
TW200726473A (en) | 2005-06-28 | 2007-07-16 | Wyeth Corp | Compositions and methods for treatment of cycle-related symptoms |
PT1787649E (pt) | 2005-10-13 | 2009-05-08 | Bayer Schering Pharma Ag | Utilização de valerato de estradiol em combinação com dienogest para a terapia oral da hemorragia uterina disfuncional em conjunto com uma contracepção oral |
US8153616B2 (en) | 2005-10-17 | 2012-04-10 | Bayer Pharma Aktiengesellschaft | Combination preparation for oral contraception and oral therapy of dysfunctional uterine bleeding containing estradiol valerate and dienogest and method of using same |
EP1930010A1 (de) | 2006-10-20 | 2008-06-11 | Bayer Schering Pharma Aktiengesellschaft | Verwendung von Estradiolvalerat oder 17ß-Estradiol in Kombination mit Dienogest zur oralen Therapie für den Erhalt und/oder die Steigerung der weiblichen Libido |
-
2004
- 2004-04-20 DE DE102004019743A patent/DE102004019743B4/de not_active Expired - Fee Related
-
2005
- 2005-03-09 MY MYPI20050962A patent/MY143669A/en unknown
- 2005-03-25 TW TW094109222A patent/TWI351960B/zh active
- 2005-04-15 US US11/578,771 patent/US8071577B2/en active Active
- 2005-04-15 PT PT05730867T patent/PT1740163E/pt unknown
- 2005-04-15 BR BRPI0510005-4A patent/BRPI0510005A/pt not_active Application Discontinuation
- 2005-04-15 WO PCT/EP2005/004022 patent/WO2005102247A2/de active Application Filing
- 2005-04-15 EA EA200601844A patent/EA010313B1/ru active Protection Beyond IP Right Term
- 2005-04-15 MX MXPA06012213A patent/MXPA06012213A/es active IP Right Grant
- 2005-04-15 KR KR1020067021681A patent/KR20060134168A/ko not_active Application Discontinuation
- 2005-04-15 UA UAA200611799A patent/UA83915C2/ru unknown
- 2005-04-15 CN CN2005800125561A patent/CN1946383B/zh active Active
- 2005-04-15 JP JP2007508800A patent/JP4908399B2/ja active Active
- 2005-04-15 CA CA002561839A patent/CA2561839C/en active Active
- 2005-04-15 DE DE502005009904T patent/DE502005009904D1/de active Active
- 2005-04-15 NZ NZ550417A patent/NZ550417A/en unknown
- 2005-04-15 ME MEP-2010-149A patent/ME01183B/me unknown
- 2005-04-15 ES ES05730867T patent/ES2348038T5/es active Active
- 2005-04-15 SI SI200531115T patent/SI1740163T2/sl unknown
- 2005-04-15 RS RS20100413A patent/RS51434B2/sr unknown
- 2005-04-15 AT AT05730867T patent/ATE473734T1/de active
- 2005-04-15 EP EP05730867.8A patent/EP1740163B2/de active Active
- 2005-04-15 AU AU2005235418A patent/AU2005235418C1/en active Active
- 2005-04-15 DK DK05730867.8T patent/DK1740163T4/da active
- 2005-04-15 PL PL05730867T patent/PL1740163T5/pl unknown
- 2005-04-20 PA PA20058630901A patent/PA8630901A1/es unknown
- 2005-04-20 AR ARP050101553A patent/AR048830A1/es not_active Application Discontinuation
- 2005-04-20 GT GT200500093A patent/GT200500093A/es unknown
- 2005-04-20 UY UY28863A patent/UY28863A1/es not_active Application Discontinuation
- 2005-04-20 PE PE2005000436A patent/PE20060308A1/es not_active Application Discontinuation
- 2005-04-20 SV SV2005002090A patent/SV2006002090A/es active IP Right Grant
-
2006
- 2006-10-05 IL IL178510A patent/IL178510A/en active IP Right Grant
- 2006-10-19 CR CR8695A patent/CR8695A/es unknown
- 2006-11-13 EC EC2006007000A patent/ECSP067000A/es unknown
- 2006-11-17 NO NO20065292A patent/NO344098B1/no unknown
- 2006-11-17 ZA ZA2006/09594A patent/ZA200609594B/en unknown
-
2007
- 2007-07-03 HK HK07107104.1A patent/HK1099701A1/xx unknown
-
2010
- 2010-03-18 US US12/726,799 patent/US20100173877A1/en not_active Abandoned
- 2010-09-17 HR HRP20100513TT patent/HRP20100513T4/hr unknown
- 2010-10-14 CY CY20101100913T patent/CY1111292T1/el unknown
-
2011
- 2011-02-04 US US13/020,913 patent/US20110124612A1/en not_active Abandoned
- 2011-12-12 AR ARP110104615A patent/AR084229A2/es not_active Application Discontinuation
-
2015
- 2015-07-09 IL IL239861A patent/IL239861A0/en unknown
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