AR056694A1 - Uso de valerato de estradiol en combinacion con dienogest para la terapia oral de la hemorragia uterina disfuncional unida con una anticoncepcion oral - Google Patents
Uso de valerato de estradiol en combinacion con dienogest para la terapia oral de la hemorragia uterina disfuncional unida con una anticoncepcion oralInfo
- Publication number
- AR056694A1 AR056694A1 ARP060104489A ARP060104489A AR056694A1 AR 056694 A1 AR056694 A1 AR 056694A1 AR P060104489 A ARP060104489 A AR P060104489A AR P060104489 A ARP060104489 A AR P060104489A AR 056694 A1 AR056694 A1 AR 056694A1
- Authority
- AR
- Argentina
- Prior art keywords
- combination
- estradiol
- units
- dienogest
- oral
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/30—Oestrogens
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Diabetes (AREA)
- Gynecology & Obstetrics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
Abstract
Se efectua el uso de valerato de estradiol en combinacion con 17alfa-cianometil-17-beta-hidroxiestra-4,9-dien-3-ona (dienogest) para producir un preparado combinado polifásico para la terapia oral de hemorragia uterina disfuncional en combinacion con una anticoncepcion oral. La combinacion de valerato de estradiol con dienogest compende en este caso una primera fase de 2 unidades de dosis diarias del valerato de estradiol de 3 mg o estradiol inferior a 3 mg, una segunda fase de 2 grupos de unidades de dosis diarias, en donde el primer grupo contiene 5 unidades de dosis diarias de una combinacion de 2 mg de valerato de estradiol o estradiol inferior a 2mg y 2 mg de dienogest y el segundo grupo contiene 17 unidades de dosis diarias de una combinacion de 2 mg de valerato de estradiol o estradiol inferior a 2mg y 3 mg de dienogest, una tercera fase de 2 unidades de dosis diarias con 1 mg de valerato de estradiol o estradiol inferior a 1 mg y otra fase de 2 unidades de dosis diarias de placebo farmacéuticamente inocuo. Todas las unidades de dosis diarias de la combinacion polifásica y del placebo farmacéuticamente inocuo corresponden a 28 días. La duracion e la aplicacion comprende al menos un ciclo de ingesta y depende del deseo individual de la mujer de la anticoncepcion.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP05022324A EP1787649B1 (de) | 2005-10-13 | 2005-10-13 | Verwendung von Estradiolvalerat in Kombination mit Dienogest zur oralen Therapie der dysfunktionellen uterinen Blutung in Einheit mit einer oralen Kontrazeption |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR056694A1 true AR056694A1 (es) | 2007-10-17 |
Family
ID=35811580
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP060104489A AR056694A1 (es) | 2005-10-13 | 2006-10-13 | Uso de valerato de estradiol en combinacion con dienogest para la terapia oral de la hemorragia uterina disfuncional unida con una anticoncepcion oral |
Country Status (22)
| Country | Link |
|---|---|
| EP (2) | EP1787649B1 (es) |
| JP (2) | JP5735200B2 (es) |
| KR (2) | KR20080065651A (es) |
| CN (1) | CN101312733A (es) |
| AR (1) | AR056694A1 (es) |
| AT (2) | ATE424828T1 (es) |
| CA (1) | CA2623024C (es) |
| CL (1) | CL2011000283A1 (es) |
| CY (2) | CY1110321T1 (es) |
| DE (2) | DE502005006837D1 (es) |
| DK (2) | DK1787649T3 (es) |
| DO (1) | DOP2006000221A (es) |
| ES (2) | ES2322479T3 (es) |
| HR (1) | HRP20090256T1 (es) |
| ME (1) | ME01056B (es) |
| PE (2) | PE20100090A1 (es) |
| PL (2) | PL1787649T3 (es) |
| PT (2) | PT1787649E (es) |
| SI (2) | SI1787649T1 (es) |
| TW (2) | TWI328453B (es) |
| UY (1) | UY29861A1 (es) |
| WO (1) | WO2007042296A1 (es) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102004019743B4 (de) | 2004-04-20 | 2008-11-27 | Bayer Schering Pharma Aktiengesellschaft | Mehrphasenpräparat zur Kontrazeption auf der Basis eines natürlichen Estrogens |
| PT1787649E (pt) * | 2005-10-13 | 2009-05-08 | Bayer Schering Pharma Ag | Utilização de valerato de estradiol em combinação com dienogest para a terapia oral da hemorragia uterina disfuncional em conjunto com uma contracepção oral |
| US8153616B2 (en) | 2005-10-17 | 2012-04-10 | Bayer Pharma Aktiengesellschaft | Combination preparation for oral contraception and oral therapy of dysfunctional uterine bleeding containing estradiol valerate and dienogest and method of using same |
| EP1930010A1 (de) | 2006-10-20 | 2008-06-11 | Bayer Schering Pharma Aktiengesellschaft | Verwendung von Estradiolvalerat oder 17ß-Estradiol in Kombination mit Dienogest zur oralen Therapie für den Erhalt und/oder die Steigerung der weiblichen Libido |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4429374C1 (de) * | 1994-08-12 | 1996-02-01 | Jenapharm Gmbh | Pharmazeutische Präparate zur Kontrazeption/Hormonsubstitution mit biogener Estrogenkomponente |
| DE19540253C2 (de) * | 1995-10-28 | 1998-06-04 | Jenapharm Gmbh | Mehrphasenpräparat zur Kontrazeption auf der Basis natürlicher Estrogene |
| CA2261748A1 (en) * | 1996-07-26 | 1998-02-05 | American Home Products Corporation | Biphasic contraceptive method and kit comprising a combination of a progestin and estrogen |
| US6251956B1 (en) | 1998-08-20 | 2001-06-26 | Ortho Pharmaceutical Corporation | Combination progestin oral contraceptive regimen |
| EP1462106A1 (en) * | 2003-03-28 | 2004-09-29 | Pantarhei Bioscience B.V. | Pharmaceutical compositions and kits comprising 17-beta-estradiol and a progesteron for the treatment of gynecological disorders |
| DE102004019743B4 (de) * | 2004-04-20 | 2008-11-27 | Bayer Schering Pharma Aktiengesellschaft | Mehrphasenpräparat zur Kontrazeption auf der Basis eines natürlichen Estrogens |
| PT1787649E (pt) * | 2005-10-13 | 2009-05-08 | Bayer Schering Pharma Ag | Utilização de valerato de estradiol em combinação com dienogest para a terapia oral da hemorragia uterina disfuncional em conjunto com uma contracepção oral |
-
2005
- 2005-10-13 PT PT05022324T patent/PT1787649E/pt unknown
- 2005-10-13 DK DK05022324T patent/DK1787649T3/da active
- 2005-10-13 AT AT05022324T patent/ATE424828T1/de active
- 2005-10-13 PL PL05022324T patent/PL1787649T3/pl unknown
- 2005-10-13 ES ES05022324T patent/ES2322479T3/es active Active
- 2005-10-13 ME MEP-2009-171A patent/ME01056B/me unknown
- 2005-10-13 EP EP05022324A patent/EP1787649B1/de not_active Revoked
- 2005-10-13 SI SI200530672T patent/SI1787649T1/sl unknown
- 2005-10-13 DE DE502005006837T patent/DE502005006837D1/de active Active
-
2006
- 2006-10-12 DE DE502006008853T patent/DE502006008853D1/de active Active
- 2006-10-12 PT PT06806225T patent/PT1933843E/pt unknown
- 2006-10-12 EP EP06806225A patent/EP1933843B1/de active Active
- 2006-10-12 CA CA2623024A patent/CA2623024C/en active Active
- 2006-10-12 PL PL06806225T patent/PL1933843T3/pl unknown
- 2006-10-12 PE PE2009001256A patent/PE20100090A1/es not_active Application Discontinuation
- 2006-10-12 WO PCT/EP2006/009867 patent/WO2007042296A1/de active Application Filing
- 2006-10-12 TW TW095137564A patent/TWI328453B/zh active
- 2006-10-12 DK DK06806225.6T patent/DK1933843T3/da active
- 2006-10-12 CN CNA2006800381810A patent/CN101312733A/zh active Pending
- 2006-10-12 KR KR1020087011203A patent/KR20080065651A/ko not_active Application Discontinuation
- 2006-10-12 SI SI200630991T patent/SI1933843T1/sl unknown
- 2006-10-12 KR KR1020107014574A patent/KR101218872B1/ko active IP Right Grant
- 2006-10-12 PE PE2006001241A patent/PE20070555A1/es not_active Application Discontinuation
- 2006-10-12 JP JP2008534936A patent/JP5735200B2/ja active Active
- 2006-10-12 ES ES06806225T patent/ES2360302T3/es active Active
- 2006-10-12 AT AT06806225T patent/ATE497387T1/de active
- 2006-10-13 DO DO2006000221A patent/DOP2006000221A/es unknown
- 2006-10-13 UY UY29861A patent/UY29861A1/es not_active Application Discontinuation
- 2006-10-13 AR ARP060104489A patent/AR056694A1/es not_active Application Discontinuation
-
2007
- 2007-01-09 TW TW096100872A patent/TW200829255A/zh unknown
-
2009
- 2009-05-05 HR HR20090256T patent/HRP20090256T1/xx unknown
- 2009-06-11 CY CY20091100621T patent/CY1110321T1/el unknown
-
2011
- 2011-02-10 CL CL2011000283A patent/CL2011000283A1/es unknown
- 2011-05-02 CY CY20111100422T patent/CY1111406T1/el unknown
-
2012
- 2012-11-19 JP JP2012253067A patent/JP2013047269A/ja active Pending
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Legal Events
| Date | Code | Title | Description |
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| FC | Refusal |