AR078085A1 - Peptidos tau antigenicos y usos de los mismos - Google Patents
Peptidos tau antigenicos y usos de los mismosInfo
- Publication number
- AR078085A1 AR078085A1 ARP100102753A ARP100102753A AR078085A1 AR 078085 A1 AR078085 A1 AR 078085A1 AR P100102753 A ARP100102753 A AR P100102753A AR P100102753 A ARP100102753 A AR P100102753A AR 078085 A1 AR078085 A1 AR 078085A1
- Authority
- AR
- Argentina
- Prior art keywords
- tau
- phospho
- epitope
- pser
- pthr
- Prior art date
Links
- 230000000890 antigenic effect Effects 0.000 title abstract 3
- 102000004196 processed proteins & peptides Human genes 0.000 title 1
- 108090000765 processed proteins & peptides Proteins 0.000 title 1
- 101000854943 Enterobacteria phage T4 Valyl-tRNA ligase modifier Proteins 0.000 abstract 3
- 230000002163 immunogen Effects 0.000 abstract 3
- 239000000203 mixture Substances 0.000 abstract 2
- 208000012902 Nervous system disease Diseases 0.000 abstract 1
- 208000025966 Neurological disease Diseases 0.000 abstract 1
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- DCWXELXMIBXGTH-QMMMGPOBSA-N phosphonotyrosine Chemical compound OC(=O)[C@@H](N)CC1=CC=C(OP(O)(O)=O)C=C1 DCWXELXMIBXGTH-QMMMGPOBSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4711—Alzheimer's disease; Amyloid plaque core protein
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Toxicology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Neurosurgery (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US22986009P | 2009-07-30 | 2009-07-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR078085A1 true AR078085A1 (es) | 2011-10-12 |
Family
ID=42941871
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP100102753A AR078085A1 (es) | 2009-07-30 | 2010-07-29 | Peptidos tau antigenicos y usos de los mismos |
Country Status (17)
Families Citing this family (46)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8552165B2 (en) * | 2008-12-09 | 2013-10-08 | Heather Davis | Immunostimulatory oligonucleotides |
| CN102333538B (zh) | 2008-12-09 | 2014-01-15 | 科勒制药集团有限公司 | 免疫刺激性寡核苷酸 |
| UA107571C2 (xx) | 2009-04-03 | 2015-01-26 | Фармацевтична композиція | |
| CA2765099A1 (en) | 2009-06-10 | 2010-12-16 | New York University | Phosphorylated tau peptide for use in the treatment of tauopathy |
| AU2013205313B2 (en) * | 2010-10-07 | 2016-05-19 | Ac Immune S.A. | Phosphospecific antibodies recognising tau |
| EP2625198B1 (en) | 2010-10-07 | 2015-07-22 | AC Immune S.A. | Antibodies recognising phospho-tau |
| CA2826286C (en) | 2011-01-31 | 2021-09-21 | Intellect Neurosciences Inc. | Treatment of tauopathies |
| AU2012282678B2 (en) | 2011-07-11 | 2016-03-03 | California Institute Of Technology | Akt-specific capture agents, compositions, and methods of using and making |
| MX339762B (es) | 2011-09-28 | 2016-05-27 | Univ Autonoma Del Estado De Morelos | Metalopeptidos inmunomoduladores (immp) y composiciones que los contienen. |
| CN108034005B (zh) | 2011-10-07 | 2021-06-25 | Ac免疫有限公司 | 识别Tau的磷酸化特异抗体 |
| WO2013151762A1 (en) | 2012-04-05 | 2013-10-10 | Ac Immune S.A. | Humanized tau antibody |
| MX359555B (es) * | 2012-07-03 | 2018-10-02 | Univ Washington | Anticuerpos para tau. |
| EP3685854A1 (en) | 2012-08-16 | 2020-07-29 | Ipierian, Inc. | Methods of treating a tauopathy |
| US8980270B2 (en) | 2013-01-18 | 2015-03-17 | Ipierian, Inc. | Methods of treating a tauopathy |
| CN105143258B (zh) | 2013-03-15 | 2020-06-23 | Ac免疫有限公司 | 抗Tau抗体和使用方法 |
| US10195257B2 (en) * | 2013-07-28 | 2019-02-05 | Qantu Therapeutics, Inc. | Vaccine formulations comprising quillaja desacylsaponins and beta amyloid peptides or tau protein to induce a Th2 immune response |
| WO2015122922A1 (en) | 2014-02-14 | 2015-08-20 | Ipierian, Inc. | Tau peptides, anti-tau antibodies, and methods of use thereof |
| TW202136296A (zh) | 2014-06-27 | 2021-10-01 | 美商C2N醫療診斷有限責任公司 | 人類化抗-tau抗體 |
| US10132818B2 (en) | 2014-07-08 | 2018-11-20 | New York University | Tau imaging ligands and their uses in the diagnosis and treatment of tauopathy |
| WO2016154522A1 (en) * | 2015-03-25 | 2016-09-29 | Stc. Unm | Immunotherapy compositions and methods for treatment of tauopathy and transgenic mouse |
| JP6937289B2 (ja) | 2015-07-06 | 2021-09-22 | ユーシービー バイオファルマ エスアールエル | Tau結合抗体 |
| CN108135986B (zh) | 2015-08-13 | 2022-07-29 | 纽约大学 | 对于Tau的截短的Asp421表位特异性的基于抗体的分子和它们在诊断和治疗Tau疾病中的用途 |
| EP3519425B1 (en) | 2016-09-29 | 2024-02-28 | Indi Molecular, Inc. | Compositions for detection, inhibition and imaging of indoleamine 2,3-dioxygenase 1 (ido1) and methods of making and using same |
| GB201700487D0 (en) | 2017-01-11 | 2017-02-22 | Hermon-Taylor John | Diagnostic |
| KR20240145065A (ko) * | 2017-10-25 | 2024-10-04 | 얀센 파마슈티칼즈, 인코포레이티드 | 인산화 타우 펩티드의 조성물 및 이의 용도 |
| AU2018355574B2 (en) * | 2017-10-27 | 2025-09-04 | United Neuroscience | Tau peptide immunogen constructs |
| CN109870581B (zh) * | 2017-12-04 | 2021-05-04 | 厦门万泰凯瑞生物技术有限公司 | 一种定量检测HBsAg的试剂盒及方法 |
| CN108314737B (zh) * | 2018-01-25 | 2021-03-16 | 中国科学院过程工程研究所 | 一种重组蛋白及其制备方法和应用 |
| CN110548135B (zh) * | 2018-05-31 | 2023-06-06 | 长春百克生物科技股份公司 | 磷酸化多肽抗原疫苗及其制备方法和应用 |
| GB201811382D0 (en) | 2018-07-11 | 2018-08-29 | Taylor John Hermon | Vaccine |
| WO2020073121A1 (en) * | 2018-10-07 | 2020-04-16 | The University Of British Columbia | Conformation-specific epitopes in alpha-synuclein, antibodies thereto and methods related thereof |
| SG11202106717PA (en) * | 2019-02-08 | 2021-07-29 | Prothena Biosciences Ltd | Antibodies recognizing tau |
| BR112021014794A2 (pt) | 2019-02-08 | 2021-10-05 | Ac Immune S.A. | Método de administração segura de vacina de peptídeo de tau fosforilada |
| WO2020186091A1 (en) * | 2019-03-12 | 2020-09-17 | Indi Molecular, Inc. | Cross-linked epitopes and methods of use thereof |
| US12201679B2 (en) | 2019-04-05 | 2025-01-21 | Institute For Systems Biology | Epitope-targeted peptide immunostimulants |
| WO2020201828A1 (en) | 2019-04-05 | 2020-10-08 | Tauc3 Biologics Limited | Anti-tauc3 antibodies and uses thereof |
| PH12021552683A1 (en) | 2019-04-24 | 2022-03-21 | Ac Immune Sa | Heterologous administration of tau vaccines |
| US12216122B2 (en) | 2019-05-20 | 2025-02-04 | Regeneron Pharmaceuticals, Inc. | Compositions and methods relating to detection, inhibition, and imaging of indoleamine 2,3-dioxygenase 1 (IDO1) |
| CN114174515A (zh) * | 2019-05-27 | 2022-03-11 | 英属哥伦比亚大学 | tau中的构象特异性表位、其抗体和其相关方法 |
| GB2585252A (en) * | 2019-07-05 | 2021-01-06 | Gen2 Neuroscience Ltd | Tau epitope and binding molecules |
| US12209142B2 (en) | 2020-05-29 | 2025-01-28 | Institute For Systems Biology | SARS-CoV-2 epitope-targeted peptide immunostimulants |
| CA3188458A1 (en) * | 2020-08-07 | 2022-02-10 | Robin Barbour | Tau vaccine for the treatment of alzheimer's disease |
| EP4212172A4 (en) * | 2020-09-08 | 2024-10-16 | Osaka University | Immunogenic composition targeting phosphorylated tau protein |
| CA3231335A1 (en) * | 2021-09-08 | 2023-03-16 | Sergei Aleksandrovich LEGOTSKII | Bispecific antibody comprising a heterodimer based on mhc proteins |
| MX2024003775A (es) * | 2021-09-29 | 2024-04-11 | Janssen Pharmaceuticals Inc | Metodo de administracion segura del conjugado de fosfopeptido de tau. |
| CN115894659B (zh) * | 2022-10-19 | 2023-11-10 | 上海优宁维生物科技股份有限公司 | 微管相关蛋白Tau抗原及其制备方法和应用 |
Family Cites Families (76)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4469863A (en) | 1980-11-12 | 1984-09-04 | Ts O Paul O P | Nonionic nucleic acid alkyl and aryl phosphonates and processes for manufacture and use thereof |
| US5023243A (en) | 1981-10-23 | 1991-06-11 | Molecular Biosystems, Inc. | Oligonucleotide therapeutic agent and method of making same |
| WO1983001451A1 (en) | 1981-10-23 | 1983-04-28 | Molecular Biosystems Inc | Oligonucleotide therapeutic agent and methods of making same |
| US4722840A (en) | 1984-09-12 | 1988-02-02 | Chiron Corporation | Hybrid particle immunogens |
| DE3525624A1 (de) | 1985-07-18 | 1987-01-22 | Celamerck Gmbh & Co Kg | Insektizid wirksames mittel zur bekaempfung von textilschaedlingen |
| US5374426A (en) | 1986-09-03 | 1994-12-20 | University Of Saskatchewan | Rotavirus nucleocapsid protein VP6 in vaccine compositions |
| GB8815795D0 (en) | 1988-07-02 | 1988-08-10 | Bkl Extrusions Ltd | Glazing bead |
| NZ230747A (en) | 1988-09-30 | 1992-05-26 | Bror Morein | Immunomodulating matrix comprising a complex of at least one lipid and at least one saponin; certain glycosylated triterpenoid saponins derived from quillaja saponaria molina |
| HU212924B (en) | 1989-05-25 | 1996-12-30 | Chiron Corp | Adjuvant formulation comprising a submicron oil droplet emulsion |
| NZ235315A (en) | 1989-09-19 | 1991-09-25 | Wellcome Found | Chimaeric hepadnavirus core antigen proteins and their construction |
| SE466259B (sv) | 1990-05-31 | 1992-01-20 | Arne Forsgren | Protein d - ett igd-bindande protein fraan haemophilus influenzae, samt anvaendning av detta foer analys, vacciner och uppreningsaendamaal |
| AU9052091A (en) | 1990-12-20 | 1992-07-22 | Smithkline Beecham Biologicals (Sa) | Vaccines based on hepatitis b surface antigen |
| EP0544942A1 (en) * | 1991-12-06 | 1993-06-09 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Novel tools for the diagnosis and treatment of Alzheimer disease |
| DE69233723T2 (de) * | 1991-12-06 | 2009-02-05 | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. | Verwendung von Proteinkinasen zur Diagnose und Behandlung der Alzheimer Krankheit |
| US7408027B1 (en) * | 1991-12-06 | 2008-08-05 | Max-Planck-Gesellschaft Zur Forderung Der Wissenchaften | Tools for the diagnosis and treatment of Alzheimer's disease |
| SK279188B6 (sk) | 1992-06-25 | 1998-07-08 | Smithkline Beecham Biologicals S.A. | Vakcínová kompozícia spôsob jej prípravy a použiti |
| ES2162139T5 (es) | 1993-03-23 | 2008-05-16 | Smithkline Beecham Biologicals S.A. | Composiciones de vacuna que contienen monofosforil-lipido a 3-o-desacilado. |
| DE4321946A1 (de) | 1993-07-01 | 1995-01-12 | Hoechst Ag | Methylphosphonsäureester, Verfahren zu deren Herstellung und deren Verwendung |
| GB9326253D0 (en) | 1993-12-23 | 1994-02-23 | Smithkline Beecham Biolog | Vaccines |
| US5658738A (en) | 1994-05-31 | 1997-08-19 | Becton Dickinson And Company | Bi-directional oligonucleotides that bind thrombin |
| US6207646B1 (en) | 1994-07-15 | 2001-03-27 | University Of Iowa Research Foundation | Immunostimulatory nucleic acid molecules |
| US6239116B1 (en) | 1994-07-15 | 2001-05-29 | University Of Iowa Research Foundation | Immunostimulatory nucleic acid molecules |
| CA2560114A1 (en) | 1994-07-15 | 1996-02-01 | The University Of Iowa Research Foundation | Immunomodulatory oligonucleotides |
| AUPM873294A0 (en) | 1994-10-12 | 1994-11-03 | Csl Limited | Saponin preparations and use thereof in iscoms |
| EP0817854A2 (en) | 1995-03-31 | 1998-01-14 | Wolf, Hans, Prof. Dr. | Antigen presentation system based on retrovirus-like particles |
| GB9513261D0 (en) | 1995-06-29 | 1995-09-06 | Smithkline Beecham Biolog | Vaccines |
| WO1997034145A1 (fr) * | 1996-03-13 | 1997-09-18 | Mitsubishi Chemical Corporation | Anticorps a proteine tau antiphosphorylee et procede de detection de la maladie d'alzheimer l'utilisant |
| GB9621091D0 (en) | 1996-10-09 | 1996-11-27 | Fondation Pour Le Perfectionem | Attenuated microorganisms strains and their uses |
| CA2268825C (en) | 1996-10-11 | 2006-04-18 | The Regents Of The University Of California | Immunostimulatory polynucleotide/immunomodulatory molecule conjugates |
| AU5508798A (en) * | 1996-11-19 | 1998-06-10 | Trustees Of The University Of Pennsylvania, The | Diagnostic and therapeutic reagents for alzheimer's disease |
| AUPO517897A0 (en) | 1997-02-19 | 1997-04-11 | Csl Limited | Chelating immunostimulating complexes |
| CA2281838A1 (en) | 1997-02-28 | 1998-09-03 | University Of Iowa Research Foundation | Use of nucleic acids containing unmethylated cpg dinucleotide in the treatment of lps-associated disorders |
| DE69841122D1 (de) | 1997-03-10 | 2009-10-15 | Coley Pharm Gmbh | Verwendung von nicht-methyliertem CpG Dinukleotid in Kombination mit Aluminium als Adjuvantien |
| EP1003531B1 (en) | 1997-05-20 | 2007-08-22 | Ottawa Health Research Institute | Processes for preparing nucleic acid constructs |
| ATE432348T1 (de) | 1997-06-06 | 2009-06-15 | Univ California | Inhibitoren von immunstimulatorischen dna sequenz aktivität |
| GB9712347D0 (en) | 1997-06-14 | 1997-08-13 | Smithkline Beecham Biolog | Vaccine |
| GB9717953D0 (en) | 1997-08-22 | 1997-10-29 | Smithkline Beecham Biolog | Vaccine |
| WO1999011241A1 (en) | 1997-09-05 | 1999-03-11 | Smithkline Beecham Biologicals S.A. | Oil in water emulsions containing saponins |
| BR9907855A (pt) | 1998-02-12 | 2001-04-24 | Immune Complex Corp | Conjugado de proteìna de núcleo de hepatite b estrategicamente modificada, partìcula de proteìna, conjugado de partìculas de proteìna, conjugado de proteìna de fusão imunogênica, inóculo, e, processo para induzir anticorpos em um hospedeiro animal |
| US6303114B1 (en) | 1998-03-05 | 2001-10-16 | The Medical College Of Ohio | IL-12 enhancement of immune responses to T-independent antigens |
| HUP0101619A3 (en) | 1998-04-09 | 2003-11-28 | Smithkline Beecham Biolog | Adjuvant compositions |
| GB9817052D0 (en) | 1998-08-05 | 1998-09-30 | Smithkline Beecham Biolog | Vaccine |
| DK1126876T3 (da) | 1998-10-16 | 2007-07-02 | Glaxosmithkline Biolog Sa | Adjuvanssystemer og vacciner |
| ES2258869T3 (es) | 1998-10-21 | 2006-09-01 | The United States Government As Represented By The Department Of Health And Human Services | Particulas similares a virus para la induccion de autoanticuerpos. |
| NZ512078A (en) | 1998-11-05 | 2004-01-30 | Powderject Vaccines Inc | Nucleic acid constructs comprising a hepatitis B core antigen and a cytolytic T lymphocyte antigen for genetic immunization |
| RU2245163C2 (ru) | 1998-11-30 | 2005-01-27 | Сайтос Байотекнолэджи АГ | Композиция (варианты), способ получения не природной упорядоченной и содержащей повторы антигенной матрицы, способ терапевтического лечения и способ иммунизации |
| AUPP807399A0 (en) | 1999-01-08 | 1999-02-04 | Csl Limited | Improved immunogenic lhrh composition and methods relating thereto |
| AU783344B2 (en) | 1999-02-17 | 2005-10-20 | Csl Limited | Immunogenic complexes and methods relating thereto |
| TWI281403B (en) | 1999-03-19 | 2007-05-21 | Smithkline Beecham Biolog | Vaccine |
| DK1187629T3 (da) | 1999-04-19 | 2005-01-17 | Glaxosmithkline Biolog Sa | Adjuvanssammensætning omfattende saponin og et immunostimulerende oligonucleotid |
| WO2001021207A2 (en) | 1999-09-24 | 2001-03-29 | Smithkline Beecham Biologicals S.A. | Use of combination of polyoxyethylene sorbitan ester and octoxynol as adjuvant and its use in vaccines |
| CA2383110A1 (en) | 1999-09-24 | 2001-03-29 | Veronique Henderickx | Adjuvant comprising a polyoxyethylene alkyl ether or ester and at least one non-ionic surfactant |
| ES2269371T3 (es) | 2000-04-07 | 2007-04-01 | University Of Leeds | Proteinas de fusion con el antigeno de la nucleocapsida de la hepatitis b. |
| CA2407897A1 (en) | 2000-05-05 | 2001-11-15 | Cytos Biotechnology Ag | Molecular antigen arrays and vaccines |
| CA2413546C (en) | 2000-06-22 | 2011-06-14 | Celltech Pharmaceuticals Limited | Modification of hepatitis b core antigen |
| WO2002005690A1 (en) | 2000-07-15 | 2002-01-24 | Lighthouse Display International Limited | Shelf edge display fittings |
| AUPQ912000A0 (en) | 2000-07-31 | 2000-08-24 | Crown In The Right Of The Queensland Department Of Health, The | Improved virus like particles |
| US20030138769A1 (en) | 2000-08-16 | 2003-07-24 | Birkett Ashley J. | Immunogenic HBc chimer particles having enhanced stability |
| US7264810B2 (en) | 2001-01-19 | 2007-09-04 | Cytos Biotechnology Ag | Molecular antigen array |
| US20030091593A1 (en) | 2001-09-14 | 2003-05-15 | Cytos Biotechnology Ag | In vivo activation of antigen presenting cells for enhancement of immune responses induced by virus like particles |
| CA2492826C (en) | 2001-09-14 | 2016-12-13 | Cytos Biotechnology Ag | Encapsulation of unmethylated cpg-containing oligonucleotides into virus-like particles: method of preparation and use |
| EP1517702A4 (en) | 2002-02-21 | 2006-05-03 | Apovia Inc | IMMUNOGENIC HBC CHIMERIC PARTICLES STABILIZED WITH AN N-TERMINAL END CYSTEINE |
| US20040176283A1 (en) | 2002-04-01 | 2004-09-09 | Robinson John A. | Methods and compositions for the design of synthetic vaccines |
| GB0209878D0 (en) | 2002-04-30 | 2002-06-05 | Glaxosmithkline Biolog Sa | Vaccine |
| RU2324704C2 (ru) | 2002-07-17 | 2008-05-20 | Цитос Байотекнолоджи Аг | Молекулярные массивы антигенов |
| CN101711865A (zh) * | 2002-07-19 | 2010-05-26 | 希托斯生物技术股份公司 | 含有淀粉样β1-6抗原阵列的疫苗组合物 |
| ATE546156T1 (de) | 2002-12-10 | 2012-03-15 | Sanofi Pasteur Biologics Co | Stabilisierte immunogene chimäre hbc-partikel |
| SI1701968T1 (sl) * | 2003-12-17 | 2015-08-31 | Wyeth Llc | Imunogeni konjugati peptidnih nosilcev in postopek izdelave istih |
| EP1776105A2 (en) | 2004-07-18 | 2007-04-25 | Coley Pharmaceutical Group, Ltd | Methods and compositions for inducing innate immune responses |
| AU2005335104C1 (en) | 2004-07-18 | 2010-10-28 | Csl Limited | Immuno stimulating complex and oligonucleotide formulations for inducing enhanced interferon-gamma responses |
| WO2006040153A2 (en) * | 2004-10-13 | 2006-04-20 | Ablynx N.V. | Single domain camelide anti -amyloid beta antibodies and polypeptides comprising the same for the treatment and diagnosis of degenarative neural diseases such as alzheimer's disease |
| US8012936B2 (en) * | 2006-03-29 | 2011-09-06 | New York University | Tau fragments for immunotherapy |
| EP1844788B1 (en) * | 2006-04-13 | 2010-07-14 | Bio Life Science Forschungs- und Entwicklungsges.m.b.H. | HER-2/neu multi-peptide vaccine |
| US20080166785A1 (en) | 2006-08-16 | 2008-07-10 | Monica Sala-Schaeffer | Polynucleotides allowing the expression and secretion of recombinant HBsAg virus-like particles containing a foreign peptide, their production and use |
| CA2765099A1 (en) * | 2009-06-10 | 2010-12-16 | New York University | Phosphorylated tau peptide for use in the treatment of tauopathy |
| FR3058624B1 (fr) | 2016-11-15 | 2018-12-07 | L'oreal | Brosse pour l'application d'un produit sur les cils et/ou les sourcils |
-
2010
- 2010-07-20 MX MX2012001194A patent/MX2012001194A/es not_active Application Discontinuation
- 2010-07-20 KR KR1020137028550A patent/KR20130127547A/ko not_active Ceased
- 2010-07-20 RU RU2012102701/10A patent/RU2518291C2/ru not_active IP Right Cessation
- 2010-07-20 CN CN201080040148.8A patent/CN102596236B/zh not_active Expired - Fee Related
- 2010-07-20 WO PCT/IB2010/053313 patent/WO2011013034A1/en not_active Ceased
- 2010-07-20 SG SG2012002390A patent/SG177637A1/en unknown
- 2010-07-20 PE PE2012000116A patent/PE20120817A1/es not_active Application Discontinuation
- 2010-07-20 IN IN446DEN2012 patent/IN2012DN00446A/en unknown
- 2010-07-20 AU AU2010277254A patent/AU2010277254B2/en not_active Ceased
- 2010-07-20 EP EP10739402A patent/EP2459214A1/en not_active Withdrawn
- 2010-07-20 NZ NZ598356A patent/NZ598356A/en not_active IP Right Cessation
- 2010-07-20 NZ NZ618391A patent/NZ618391A/en not_active IP Right Cessation
- 2010-07-20 CA CA2768346A patent/CA2768346A1/en not_active Abandoned
- 2010-07-20 JP JP2012522292A patent/JP2013500326A/ja active Pending
- 2010-07-20 KR KR1020127005415A patent/KR20120049900A/ko not_active Abandoned
- 2010-07-29 TW TW103104138A patent/TW201436804A/zh unknown
- 2010-07-29 US US12/846,719 patent/US20110177109A1/en not_active Abandoned
- 2010-07-29 TW TW099125165A patent/TWI461209B/zh not_active IP Right Cessation
- 2010-07-29 AR ARP100102753A patent/AR078085A1/es unknown
-
2012
- 2012-02-15 CO CO12026764A patent/CO6612199A2/es unknown
-
2014
- 2014-03-31 RU RU2014112002/10A patent/RU2014112002A/ru not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| US20110177109A1 (en) | 2011-07-21 |
| TWI461209B (zh) | 2014-11-21 |
| MX2012001194A (es) | 2012-03-07 |
| AU2010277254A1 (en) | 2012-02-09 |
| RU2014112002A (ru) | 2015-10-10 |
| NZ598356A (en) | 2014-06-27 |
| TW201436804A (zh) | 2014-10-01 |
| WO2011013034A1 (en) | 2011-02-03 |
| CA2768346A1 (en) | 2011-02-03 |
| JP2013500326A (ja) | 2013-01-07 |
| IN2012DN00446A (cg-RX-API-DMAC7.html) | 2015-05-15 |
| AU2010277254B2 (en) | 2015-05-07 |
| PE20120817A1 (es) | 2012-07-07 |
| RU2518291C2 (ru) | 2014-06-10 |
| CO6612199A2 (es) | 2013-02-01 |
| KR20130127547A (ko) | 2013-11-22 |
| TW201106968A (en) | 2011-03-01 |
| NZ618391A (en) | 2015-07-31 |
| RU2012102701A (ru) | 2013-09-10 |
| SG177637A1 (en) | 2012-03-29 |
| WO2011013034A4 (en) | 2011-04-28 |
| CN102596236B (zh) | 2015-06-24 |
| CN102596236A (zh) | 2012-07-18 |
| EP2459214A1 (en) | 2012-06-06 |
| KR20120049900A (ko) | 2012-05-17 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AR078085A1 (es) | Peptidos tau antigenicos y usos de los mismos | |
| CO6501190A2 (es) | Vacuna de pcsk9 | |
| CR20130016A (es) | ANTICUERPOS PEPTIDICOS BETA AMILOIDE ANTI-N3pGlu Y USOS DE LOS MISMOS | |
| ZA202001564B (en) | Anti- folate receptor alpha antibody conjugates and their uses | |
| MX2022014980A (es) | Conjugados de polipeptido-antigeno con aminoacidos no naturales. | |
| AR113792A1 (es) | Composiciones de péptidos tau fosforilados y sus usos | |
| CY1119376T1 (el) | Αντισωματα ειδικα για τη μορφη πρωτοϊνιδιου της βητα-αμυλοειδους πρωτεϊνης | |
| EP2562183A8 (en) | Novel immunogenic epitopes for immunotherapy | |
| RU2015142996A (ru) | Пептидная вакцина для предупреждения и иммунотерапии деменции альцгеймеровского типа | |
| JP2013181034A5 (cg-RX-API-DMAC7.html) | ||
| PT2121731E (pt) | Vacinas peptídicas para cancros que expressam antigénios associados a tumores | |
| CY1107973T1 (el) | Σχετιζομενα με ογκους πεπτιδια, που συνδεονται ετεροκλητως με μορια κλασεως ιι αντιγονου ανθρωπινων λευκοκυτταρων | |
| WO2008124646A3 (en) | Use of amyloid proteins as vaccine scaffolds | |
| CR20150016A (es) | Anticuerpo monoclonal | |
| BRPI0715396B8 (pt) | método de produção de uma composição para vacina | |
| RU2007145052A (ru) | Композиции пептидного конъюгата и способы для профилактики и лечения болезни альцгеймера | |
| TW200801035A (en) | Peptide vaccine for producing anti-amyloid beta peptide antibody | |
| UY31101A1 (es) | Composición antigénica liofilizada | |
| BR112018015238A2 (pt) | conjugado de anticorpo, anticorpo, kit, composição farmacêutica, e, métodos para tratar ou prevenir uma doença ou condição e para diagnosticar uma doença ou condição | |
| GT201100023A (es) | Anticuerpos neutralizantes del virus anti - influenza a y usos de los mismos | |
| PE20142115A1 (es) | Composiciones de neisseria meningitidis y metodos de las mismas | |
| DE602005015990D1 (de) | Immunogene t-helfer epitope von menschlichen tumorantigenen und deren verwendung in immunotherapeutischen methoden | |
| WO2010016912A3 (en) | Immunotherapeutic compositions for the treatment of alzheimer's disease | |
| RU2010126154A (ru) | Эпитопные пептиды stat3 | |
| WO2009072555A1 (ja) | 癌ワクチン |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |