AR075418A1 - Polimorfo cristalino de 3-{[5-(azetidin-1-ilcarbonil)pirazin-2-il]oxi}-5-{[(1s)-1-metil-2-(metiloxi)etil]oxi}-n-(5-metilpirazin-2-il)benzamida,composiciones farmaceuticas que los contienen, proceso para prepararla y uso de las mismas para el tratamiento de la diabetes tipo ii y/u obesidad. - Google Patents

Polimorfo cristalino de 3-{[5-(azetidin-1-ilcarbonil)pirazin-2-il]oxi}-5-{[(1s)-1-metil-2-(metiloxi)etil]oxi}-n-(5-metilpirazin-2-il)benzamida,composiciones farmaceuticas que los contienen, proceso para prepararla y uso de las mismas para el tratamiento de la diabetes tipo ii y/u obesidad.

Info

Publication number
AR075418A1
AR075418A1 ARP100100413A ARP100100413A AR075418A1 AR 075418 A1 AR075418 A1 AR 075418A1 AR P100100413 A ARP100100413 A AR P100100413A AR P100100413 A ARP100100413 A AR P100100413A AR 075418 A1 AR075418 A1 AR 075418A1
Authority
AR
Argentina
Prior art keywords
oxi
metiloxi
methylpirazin
ilcarbonil
pirazin
Prior art date
Application number
ARP100100413A
Other languages
English (en)
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of AR075418A1 publication Critical patent/AR075418A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4965—Non-condensed pyrazines
    • A61K31/497—Non-condensed pyrazines containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Reivindicacion 1: Una forma cristalina del compuesto de formula (1), que tiene un patron de difraccion de rayos X en polvo con picos a un valor d (L) de 11,8 y 5,7. Reivindicacion 2: Una forma cristalina de acuerdo con la reivindicacion 1, que tiene un patron de difraccion de rayos X en polvo con picos a un valor d (L) de 11,8; 10,5; 6,4; 5,9 y 5,7.
ARP100100413A 2009-02-13 2010-02-12 Polimorfo cristalino de 3-{[5-(azetidin-1-ilcarbonil)pirazin-2-il]oxi}-5-{[(1s)-1-metil-2-(metiloxi)etil]oxi}-n-(5-metilpirazin-2-il)benzamida,composiciones farmaceuticas que los contienen, proceso para prepararla y uso de las mismas para el tratamiento de la diabetes tipo ii y/u obesidad. AR075418A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0902406.8A GB0902406D0 (en) 2009-02-13 2009-02-13 Crystalline polymorphic form

Publications (1)

Publication Number Publication Date
AR075418A1 true AR075418A1 (es) 2011-03-30

Family

ID=40548139

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP100100413A AR075418A1 (es) 2009-02-13 2010-02-12 Polimorfo cristalino de 3-{[5-(azetidin-1-ilcarbonil)pirazin-2-il]oxi}-5-{[(1s)-1-metil-2-(metiloxi)etil]oxi}-n-(5-metilpirazin-2-il)benzamida,composiciones farmaceuticas que los contienen, proceso para prepararla y uso de las mismas para el tratamiento de la diabetes tipo ii y/u obesidad.

Country Status (15)

Country Link
US (1) US8093252B2 (es)
EP (1) EP2396317A1 (es)
JP (1) JP2012517990A (es)
KR (1) KR20110120941A (es)
CN (1) CN102395580B (es)
AR (1) AR075418A1 (es)
AU (1) AU2010212605A1 (es)
BR (1) BRPI1008340A2 (es)
CA (1) CA2749994A1 (es)
GB (1) GB0902406D0 (es)
MX (1) MX2011008576A (es)
RU (1) RU2011135628A (es)
TW (1) TW201040161A (es)
UY (1) UY32446A (es)
WO (1) WO2010092386A1 (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
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TW200600086A (en) * 2004-06-05 2006-01-01 Astrazeneca Ab Chemical compound
TW200714597A (en) * 2005-05-27 2007-04-16 Astrazeneca Ab Chemical compounds
TW200825060A (en) * 2006-10-26 2008-06-16 Astrazeneca Ab Chemical compounds
CN102171213A (zh) * 2008-08-04 2011-08-31 阿斯利康(瑞典)有限公司 吡唑并[3，4]嘧啶-4-基衍生物及其治疗糖尿病和肥胖症的用途
GB0902434D0 (en) * 2009-02-13 2009-04-01 Astrazeneca Ab Chemical process
WO2010116177A1 (en) 2009-04-09 2010-10-14 Astrazeneca Ab A pyrazolo [4,5-e] pyrimidine derivative and its use to treat diabetes and obesity
AR076221A1 (es) * 2009-04-09 2011-05-26 Astrazeneca Ab Derivado de pirazol [4,5-e] pirimidina y su uso para tratar diabetes y obesidad
KR20240063930A (ko) 2021-09-02 2024-05-10 콘두이트 유케이 매니지먼트 엘티디 3-{[5-(아제티딘-1-일카르보닐)피라진-2-일]옥시}-5-{[(1s)-1-메틸-2-(메틸옥시)에틸]옥시)-n-(5-메틸피라진-2-일)벤즈아미드의치료 공결정

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Also Published As

Publication number Publication date
CA2749994A1 (en) 2010-08-19
AU2010212605A1 (en) 2011-08-04
BRPI1008340A2 (pt) 2016-02-23
CN102395580B (zh) 2014-03-12
MX2011008576A (es) 2011-09-06
TW201040161A (en) 2010-11-16
US8093252B2 (en) 2012-01-10
UY32446A (es) 2010-09-30
EP2396317A1 (en) 2011-12-21
RU2011135628A (ru) 2013-03-20
JP2012517990A (ja) 2012-08-09
CN102395580A (zh) 2012-03-28
KR20110120941A (ko) 2011-11-04
US20100210621A1 (en) 2010-08-19
WO2010092386A1 (en) 2010-08-19
GB0902406D0 (en) 2009-04-01

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