AR074772A1 - Compuestos tri- funcionales absorbentes uv y su uso - Google Patents

Compuestos tri- funcionales absorbentes uv y su uso

Info

Publication number
AR074772A1
AR074772A1 ARP090104940A ARP090104940A AR074772A1 AR 074772 A1 AR074772 A1 AR 074772A1 AR P090104940 A ARP090104940 A AR P090104940A AR P090104940 A ARP090104940 A AR P090104940A AR 074772 A1 AR074772 A1 AR 074772A1
Authority
AR
Argentina
Prior art keywords
alkyl
radical
group
independent
branched
Prior art date
Application number
ARP090104940A
Other languages
English (en)
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of AR074772A1 publication Critical patent/AR074772A1/es

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/16Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • C07D249/18Benzotriazoles
    • C07D249/20Benzotriazoles with aryl radicals directly attached in position 2
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B1/00Optical elements characterised by the material of which they are made; Optical coatings for optical elements
    • G02B1/04Optical elements characterised by the material of which they are made; Optical coatings for optical elements made of organic materials, e.g. plastics
    • G02B1/041Lenses
    • G02B1/043Contact lenses
    • GPHYSICS
    • G02OPTICS
    • G02CSPECTACLES; SUNGLASSES OR GOGGLES INSOFAR AS THEY HAVE THE SAME FEATURES AS SPECTACLES; CONTACT LENSES
    • G02C7/00Optical parts
    • G02C7/02Lenses; Lens systems ; Methods of designing lenses
    • G02C7/04Contact lenses for the eyes

Abstract

Se describen en la presente compuestos tri-funcionales de utilidad en la producción de lentes oftálmicas. Los compuestos constan de un absorbente UV que tiene un iniciador de polimerización directa o indirectamente ligado al absorbente ultravioleta, y un grupo olefínico directa o indirectamente ligado al absorbente ultravioleta. También se describen en la presente polímeros y lentes oftálmicas que se producen a partir de los compuestos tri-funcionales que se describen en la presente. Reivindicación 2: El compuesto de acuerdo con la reivindicación 1, donde el compuesto comprende la fórmula 1 Y-L2-Z-L1-X donde Z es un radical divalente de la fórmula (1a), (1b), (1c) o (1d) en donde R3a, R3b, R3c, R2z, R3z, R4Z, y R1z, independientes entre sí, son hidrógeno, halógeno, un grupo alquilo C1-12 lineal o ramificado, un grupo alcoxi C1-12 lineal o ramificado , o un grupo arilo C6-24 o arilo sustituido, PG es un grupo protector lábil; X es un radical monovalente que comprende una porción de inicio de polimerización seleccionada del grupo formado por óxido de fosfina (-C(=O)-P(=O)-), un grupo peróxido, un grupo azida, una alfa-hidroxicetona, o una alfa-aminocetona; Y es un radical monovalente de la fórmula (2) *-(Z1-A5-C(=O))q1-(Z2)q2-C(R14)=CR15R16 en la cual Z1 y Z2, independientes entre sí son un enlace covalente, un radical divalente alquileno C1-12 lineal o ramificado, un radical divalente alquileno C1-12 lineal o ramificado que tiene uno o más grupos hidroxilo, un radical de -(CH2CH2O)d-CH2CH2- en el cual d es un número entero de 1 a 10, un radical divalente fenileno sin sustituir, radical divalente alquilo C1-4 o alcoxi C1-4 fenileno sustituido, radical divalente aralquileno C7-12, -O- o -N(R')- en el cual R' es H o alquilo C1-8; A5 es un enlace covalente, -O- o -N(R')- en el cual R' es H o alquilo C1-8; q1 y q2 independientes entre sí son un número entero de 0 ó 1; R14 es hidrógeno, alquilo C1-4 o halógeno; R15 y R16 independientes entre sí son hidrógeno, alquilo C1-4 , fenilo, carboxi, halógeno, o un a radical de -C(=O)-X3-R17 en el cual X3 es -O-, -N(R')- según se definió con anterioridad o -S- y R17 es un alquilo C1-12, hidroxialquilo C1-12, aminoalquilo C1-12 , alquilaminoalquilo que tiene hasta 12 átomos de carbono, o dialquilaminoalquilo que tiene hasta 12 átomos de carbono; y L1 y L2 independientes entre sí son un enlace covalente o un ligador.
ARP090104940A 2008-12-30 2009-12-17 Compuestos tri- funcionales absorbentes uv y su uso AR074772A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US14126508P 2008-12-30 2008-12-30

Publications (1)

Publication Number Publication Date
AR074772A1 true AR074772A1 (es) 2011-02-09

Family

ID=42022208

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP090104940A AR074772A1 (es) 2008-12-30 2009-12-17 Compuestos tri- funcionales absorbentes uv y su uso

Country Status (16)

Country Link
US (1) US8324256B2 (es)
EP (1) EP2379512B1 (es)
JP (1) JP5597647B2 (es)
KR (1) KR101562087B1 (es)
CN (1) CN102264709B (es)
AR (1) AR074772A1 (es)
AU (1) AU2009333223B2 (es)
BR (1) BRPI0923725A2 (es)
CA (1) CA2744060C (es)
MX (1) MX2011007136A (es)
MY (1) MY151232A (es)
NZ (1) NZ592656A (es)
RU (1) RU2544540C2 (es)
SG (1) SG172394A1 (es)
TW (1) TWI465440B (es)
WO (1) WO2010078001A1 (es)

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US20100168359A1 (en) 2010-07-01
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CN102264709B (zh) 2014-12-31
EP2379512A1 (en) 2011-10-26
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BRPI0923725A2 (pt) 2015-08-04
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