AR070935A1 - Proceso catalitico para hidrogenacion asimetrica - Google Patents
Proceso catalitico para hidrogenacion asimetricaInfo
- Publication number
- AR070935A1 AR070935A1 ARP090100969A AR070935A1 AR 070935 A1 AR070935 A1 AR 070935A1 AR P090100969 A ARP090100969 A AR P090100969A AR 070935 A1 AR070935 A1 AR 070935A1
- Authority
- AR
- Argentina
- Prior art keywords
- formula
- compound
- enantiomer
- alkyl
- halogen
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 5
- 238000009876 asymmetric hydrogenation reaction Methods 0.000 title abstract 3
- 230000003197 catalytic effect Effects 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 13
- 125000003118 aryl group Chemical group 0.000 abstract 10
- 229910052736 halogen Inorganic materials 0.000 abstract 10
- 150000002367 halogens Chemical class 0.000 abstract 10
- 125000000217 alkyl group Chemical group 0.000 abstract 9
- 125000003545 alkoxy group Chemical group 0.000 abstract 8
- 239000003446 ligand Substances 0.000 abstract 6
- 229910052739 hydrogen Inorganic materials 0.000 abstract 5
- 239000001257 hydrogen Substances 0.000 abstract 5
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical group [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 4
- 125000003282 alkyl amino group Chemical group 0.000 abstract 4
- 125000003806 alkyl carbonyl amino group Chemical group 0.000 abstract 4
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical group [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 4
- 239000003054 catalyst Substances 0.000 abstract 4
- 125000004663 dialkyl amino group Chemical group 0.000 abstract 4
- -1 hydroxycarbonyl groups Chemical group 0.000 abstract 4
- 238000004519 manufacturing process Methods 0.000 abstract 4
- 125000000325 methylidene group Chemical group [H]C([H])=* 0.000 abstract 4
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 4
- 229910052760 oxygen Inorganic materials 0.000 abstract 4
- 239000001301 oxygen Chemical group 0.000 abstract 4
- 229910052717 sulfur Chemical group 0.000 abstract 4
- 239000011593 sulfur Chemical group 0.000 abstract 4
- 229910052723 transition metal Inorganic materials 0.000 abstract 4
- 150000003624 transition metals Chemical class 0.000 abstract 4
- 150000002431 hydrogen Chemical class 0.000 abstract 3
- ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical group [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 abstract 2
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical group [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 2
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical group [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
- 125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 2
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Chemical group BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 2
- 229910052794 bromium Inorganic materials 0.000 abstract 2
- 229910052801 chlorine Inorganic materials 0.000 abstract 2
- 239000000460 chlorine Chemical group 0.000 abstract 2
- 229910052731 fluorine Inorganic materials 0.000 abstract 2
- 239000011737 fluorine Substances 0.000 abstract 2
- 125000001153 fluoro group Chemical group F* 0.000 abstract 2
- 125000001183 hydrocarbyl group Chemical group 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- 229910052740 iodine Chemical group 0.000 abstract 2
- 239000011630 iodine Chemical group 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 1
- CUJRVFIICFDLGR-UHFFFAOYSA-N acetylacetonate Chemical compound CC(=O)[CH-]C(C)=O CUJRVFIICFDLGR-UHFFFAOYSA-N 0.000 abstract 1
- 125000002877 alkyl aryl group Chemical group 0.000 abstract 1
- 125000004429 atom Chemical group 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 229940125904 compound 1 Drugs 0.000 abstract 1
- PXBRQCKWGAHEHS-UHFFFAOYSA-N dichlorodifluoromethane Chemical compound FC(F)(Cl)Cl PXBRQCKWGAHEHS-UHFFFAOYSA-N 0.000 abstract 1
- 125000001072 heteroaryl group Chemical group 0.000 abstract 1
- 125000001624 naphthyl group Chemical group 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
- C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
- C07F15/0046—Ruthenium compounds
- C07F15/0053—Ruthenium compounds without a metal-carbon linkage
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
- C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
- C07F15/0073—Rhodium compounds
- C07F15/008—Rhodium compounds without a metal-carbon linkage
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Pyrane Compounds (AREA)
- Catalysts (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US3778408P | 2008-03-19 | 2008-03-19 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR070935A1 true AR070935A1 (es) | 2010-05-12 |
Family
ID=40786839
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP090100969 AR070935A1 (es) | 2008-03-19 | 2009-03-18 | Proceso catalitico para hidrogenacion asimetrica |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US8957222B2 (https=) |
| EP (1) | EP2297042B1 (https=) |
| JP (1) | JP2011515390A (https=) |
| KR (1) | KR20110015412A (https=) |
| CN (1) | CN102056846A (https=) |
| AR (1) | AR070935A1 (https=) |
| AU (1) | AU2009226222A1 (https=) |
| BR (1) | BRPI0906174A2 (https=) |
| CA (1) | CA2716694A1 (https=) |
| ES (1) | ES2429120T3 (https=) |
| MX (1) | MX2010010062A (https=) |
| PT (1) | PT2297042E (https=) |
| RU (1) | RU2010142900A (https=) |
| WO (1) | WO2009116883A2 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT2297042E (pt) | 2008-03-19 | 2013-10-10 | Bial Portela & Ca Sa | Hidrogenação catalítica assimétrica |
| CA3121743A1 (en) * | 2009-01-15 | 2010-07-22 | Incyte Holdings Corporation | Processes for preparing jak inhibitors and related intermediate compounds |
| CN106977486B (zh) * | 2017-05-25 | 2019-09-24 | 南方科技大学 | 一种手性二氢黄酮类化合物及其衍生物的制备方法和应用 |
| CN110841720B (zh) * | 2019-11-29 | 2022-11-18 | 河南师范大学 | 石墨烯吸附多组分手性催化剂及其在不对称氢化中的应用 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5144050A (en) | 1991-10-01 | 1992-09-01 | Monsanto Company | Ruthenium(II)-BINAP diketonate complexes |
| DE60027734T2 (de) * | 1999-09-20 | 2007-04-05 | The Penn State Research Foundation | Chirale phosphine, deren komplexe mit übergangsmetallen und deren verwendung in asymmetrischen synthesereaktionen |
| WO2002040491A1 (en) * | 2000-11-17 | 2002-05-23 | The Penn State Research Foundation | Ortho substituted chiral phosphines and phosphinites and their use in asymmetric catayltic reactions |
| US7125904B2 (en) | 2002-10-11 | 2006-10-24 | Portela & C.A., S.A. | Peripherally-selective inhibitors of dopamine-β-hydroxylase and method of their preparation |
| KR20090091326A (ko) * | 2006-12-12 | 2009-08-27 | 바이알 - 포르텔라 앤드 씨에이 에스에이 | 촉매적 비대칭 수소화 방법 |
| PT2297042E (pt) | 2008-03-19 | 2013-10-10 | Bial Portela & Ca Sa | Hidrogenação catalítica assimétrica |
-
2009
- 2009-03-17 PT PT09721339T patent/PT2297042E/pt unknown
- 2009-03-17 WO PCT/PT2009/000014 patent/WO2009116883A2/en not_active Ceased
- 2009-03-17 MX MX2010010062A patent/MX2010010062A/es not_active Application Discontinuation
- 2009-03-17 JP JP2011500723A patent/JP2011515390A/ja active Pending
- 2009-03-17 CA CA2716694A patent/CA2716694A1/en not_active Abandoned
- 2009-03-17 CN CN2009801095330A patent/CN102056846A/zh active Pending
- 2009-03-17 ES ES09721339T patent/ES2429120T3/es active Active
- 2009-03-17 US US12/921,966 patent/US8957222B2/en not_active Expired - Fee Related
- 2009-03-17 RU RU2010142900/05A patent/RU2010142900A/ru not_active Application Discontinuation
- 2009-03-17 AU AU2009226222A patent/AU2009226222A1/en not_active Abandoned
- 2009-03-17 EP EP09721339.1A patent/EP2297042B1/en not_active Not-in-force
- 2009-03-17 KR KR1020107023164A patent/KR20110015412A/ko not_active Withdrawn
- 2009-03-18 AR ARP090100969 patent/AR070935A1/es unknown
- 2009-09-17 BR BRPI0906174-6A patent/BRPI0906174A2/pt not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| ES2429120T3 (es) | 2013-11-13 |
| KR20110015412A (ko) | 2011-02-15 |
| CA2716694A1 (en) | 2009-09-24 |
| WO2009116883A8 (en) | 2009-12-10 |
| WO2009116883A3 (en) | 2010-04-01 |
| WO2009116883A2 (en) | 2009-09-24 |
| US8957222B2 (en) | 2015-02-17 |
| BRPI0906174A2 (pt) | 2015-06-30 |
| PT2297042E (pt) | 2013-10-10 |
| JP2011515390A (ja) | 2011-05-19 |
| AU2009226222A1 (en) | 2009-09-24 |
| RU2010142900A (ru) | 2012-04-27 |
| EP2297042A2 (en) | 2011-03-23 |
| MX2010010062A (es) | 2010-09-30 |
| EP2297042B1 (en) | 2013-07-10 |
| CN102056846A (zh) | 2011-05-11 |
| US20110112303A1 (en) | 2011-05-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |