CN102056846A - 催化不对称氢化 - Google Patents

催化不对称氢化 Download PDF

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Publication number
CN102056846A
CN102056846A CN2009801095330A CN200980109533A CN102056846A CN 102056846 A CN102056846 A CN 102056846A CN 2009801095330 A CN2009801095330 A CN 2009801095330A CN 200980109533 A CN200980109533 A CN 200980109533A CN 102056846 A CN102056846 A CN 102056846A
Authority
CN
China
Prior art keywords
compound
thione
catalyst
dihydroimidazole
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN2009801095330A
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English (en)
Chinese (zh)
Inventor
D·A·利尔芒斯
A·比里亚夫
W·李
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bial Portela and Cia SA
Original Assignee
Bial Portela and Cia SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bial Portela and Cia SA filed Critical Bial Portela and Cia SA
Publication of CN102056846A publication Critical patent/CN102056846A/zh
Pending legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0046—Ruthenium compounds
    • C07F15/0053—Ruthenium compounds without a metal-carbon linkage
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0073—Rhodium compounds
    • C07F15/008—Rhodium compounds without a metal-carbon linkage

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pyrane Compounds (AREA)
  • Catalysts (AREA)
CN2009801095330A 2008-03-19 2009-03-17 催化不对称氢化 Pending CN102056846A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US3778408P 2008-03-19 2008-03-19
US61/037,784 2008-03-19
PCT/PT2009/000014 WO2009116883A2 (en) 2008-03-19 2009-03-17 Catalytic asymetric hydrogenation

Publications (1)

Publication Number Publication Date
CN102056846A true CN102056846A (zh) 2011-05-11

Family

ID=40786839

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2009801095330A Pending CN102056846A (zh) 2008-03-19 2009-03-17 催化不对称氢化

Country Status (14)

Country Link
US (1) US8957222B2 (https=)
EP (1) EP2297042B1 (https=)
JP (1) JP2011515390A (https=)
KR (1) KR20110015412A (https=)
CN (1) CN102056846A (https=)
AR (1) AR070935A1 (https=)
AU (1) AU2009226222A1 (https=)
BR (1) BRPI0906174A2 (https=)
CA (1) CA2716694A1 (https=)
ES (1) ES2429120T3 (https=)
MX (1) MX2010010062A (https=)
PT (1) PT2297042E (https=)
RU (1) RU2010142900A (https=)
WO (1) WO2009116883A2 (https=)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106977486A (zh) * 2017-05-25 2017-07-25 南方科技大学 一种手性二氢黄酮类化合物及其衍生物的制备方法和应用
CN110841720A (zh) * 2019-11-29 2020-02-28 河南师范大学 石墨烯吸附多组分手性催化剂及其在不对称氢化中的应用

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT2297042E (pt) 2008-03-19 2013-10-10 Bial Portela & Ca Sa Hidrogenação catalítica assimétrica
CA3121743A1 (en) * 2009-01-15 2010-07-22 Incyte Holdings Corporation Processes for preparing jak inhibitors and related intermediate compounds

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001021625A1 (en) * 1999-09-20 2001-03-29 The Penn State Research Foundation Chiral phosphines, transition metal complexes thereof and uses thereof in asymmetric reactions
WO2002040491A1 (en) * 2000-11-17 2002-05-23 The Penn State Research Foundation Ortho substituted chiral phosphines and phosphinites and their use in asymmetric catayltic reactions

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5144050A (en) 1991-10-01 1992-09-01 Monsanto Company Ruthenium(II)-BINAP diketonate complexes
US7125904B2 (en) 2002-10-11 2006-10-24 Portela & C.A., S.A. Peripherally-selective inhibitors of dopamine-β-hydroxylase and method of their preparation
KR20090091326A (ko) * 2006-12-12 2009-08-27 바이알 - 포르텔라 앤드 씨에이 에스에이 촉매적 비대칭 수소화 방법
PT2297042E (pt) 2008-03-19 2013-10-10 Bial Portela & Ca Sa Hidrogenação catalítica assimétrica

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001021625A1 (en) * 1999-09-20 2001-03-29 The Penn State Research Foundation Chiral phosphines, transition metal complexes thereof and uses thereof in asymmetric reactions
WO2002040491A1 (en) * 2000-11-17 2002-05-23 The Penn State Research Foundation Ortho substituted chiral phosphines and phosphinites and their use in asymmetric catayltic reactions

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
PHILIPPE DUPAU ET AL.: "New route to optically active amine derivatives: ruthenium-catalyzed enantioselective hydrogenation of ene carbamates", 《TETRAHEDRON: ASYMMETRY》 *

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106977486A (zh) * 2017-05-25 2017-07-25 南方科技大学 一种手性二氢黄酮类化合物及其衍生物的制备方法和应用
CN106977486B (zh) * 2017-05-25 2019-09-24 南方科技大学 一种手性二氢黄酮类化合物及其衍生物的制备方法和应用
CN110841720A (zh) * 2019-11-29 2020-02-28 河南师范大学 石墨烯吸附多组分手性催化剂及其在不对称氢化中的应用
CN110841720B (zh) * 2019-11-29 2022-11-18 河南师范大学 石墨烯吸附多组分手性催化剂及其在不对称氢化中的应用

Also Published As

Publication number Publication date
ES2429120T3 (es) 2013-11-13
KR20110015412A (ko) 2011-02-15
CA2716694A1 (en) 2009-09-24
WO2009116883A8 (en) 2009-12-10
WO2009116883A3 (en) 2010-04-01
WO2009116883A2 (en) 2009-09-24
US8957222B2 (en) 2015-02-17
AR070935A1 (es) 2010-05-12
BRPI0906174A2 (pt) 2015-06-30
PT2297042E (pt) 2013-10-10
JP2011515390A (ja) 2011-05-19
AU2009226222A1 (en) 2009-09-24
RU2010142900A (ru) 2012-04-27
EP2297042A2 (en) 2011-03-23
MX2010010062A (es) 2010-09-30
EP2297042B1 (en) 2013-07-10
US20110112303A1 (en) 2011-05-12

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Application publication date: 20110511