AR069844A1 - Microcapsulas lipidicas solidas que contienen un nucleo interior con microparticulas de hormona de crecimiento. formulacion farmaceutica. proceso de preparacion - Google Patents

Microcapsulas lipidicas solidas que contienen un nucleo interior con microparticulas de hormona de crecimiento. formulacion farmaceutica. proceso de preparacion

Info

Publication number
AR069844A1
AR069844A1 ARP080105563A ARP080105563A AR069844A1 AR 069844 A1 AR069844 A1 AR 069844A1 AR P080105563 A ARP080105563 A AR P080105563A AR P080105563 A ARP080105563 A AR P080105563A AR 069844 A1 AR069844 A1 AR 069844A1
Authority
AR
Argentina
Prior art keywords
microcapsules according
growth hormone
sugar
microcapsules
outer shell
Prior art date
Application number
ARP080105563A
Other languages
English (en)
Spanish (es)
Inventor
Helen Gabriela Baldascini
Rita Agostinetto
Joel Richard
Frantz Deschamps
Angelis Luisa De
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of AR069844A1 publication Critical patent/AR069844A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5015—Organic compounds, e.g. fats, sugars
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/27—Growth hormone [GH], i.e. somatotropin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Endocrinology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Dispersion Chemistry (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ARP080105563A 2007-12-21 2008-12-19 Microcapsulas lipidicas solidas que contienen un nucleo interior con microparticulas de hormona de crecimiento. formulacion farmaceutica. proceso de preparacion AR069844A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP07024906 2007-12-21

Publications (1)

Publication Number Publication Date
AR069844A1 true AR069844A1 (es) 2010-02-24

Family

ID=40566364

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP080105563A AR069844A1 (es) 2007-12-21 2008-12-19 Microcapsulas lipidicas solidas que contienen un nucleo interior con microparticulas de hormona de crecimiento. formulacion farmaceutica. proceso de preparacion

Country Status (15)

Country Link
US (1) US8729015B2 (enExample)
EP (1) EP2231120B1 (enExample)
JP (1) JP5773651B2 (enExample)
KR (1) KR20100103846A (enExample)
CN (1) CN101903014B (enExample)
AR (1) AR069844A1 (enExample)
AT (1) ATE514417T1 (enExample)
AU (1) AU2008340785B8 (enExample)
BR (1) BRPI0821359A2 (enExample)
CA (1) CA2710062C (enExample)
EA (1) EA201001002A1 (enExample)
ES (1) ES2367093T3 (enExample)
IL (1) IL206393A (enExample)
WO (1) WO2009080164A1 (enExample)
ZA (1) ZA201005167B (enExample)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8729015B2 (en) 2007-12-21 2014-05-20 Merck Patent Gmbh Solid lipid microcapsules containing growth hormone inner core microparticles
WO2010017965A2 (en) * 2008-08-11 2010-02-18 Merck Serono S.A. SOLID LIPID MICROCAPSULES CONTAINING hGH
CN102370630B (zh) * 2010-08-11 2014-04-02 中国科学院过程工程研究所 重组人生长激素rhGH长效缓释微囊及其制备方法
AU2012340107B2 (en) 2011-11-18 2017-06-15 Regeneron Pharmaceuticals, Inc. Polymer protein microparticles
WO2015200054A2 (en) 2014-06-24 2015-12-30 The Trustees Of Princeton University Process for encapsulating soluble biologics, therapeutics, and imaging agents
KR101602138B1 (ko) 2014-11-21 2016-03-10 강원대학교산학협력단 염화칼슘 미세입자가 봉입된 온도 의존성 고체지질입자 및 그 제조방법
WO2017112828A1 (en) * 2015-12-22 2017-06-29 The Trustees Of Princeton University Process for encapsulating soluble biologics, therapeutics, and imaging agents
KR20170079409A (ko) * 2015-12-30 2017-07-10 한미약품 주식회사 지속형 인간 성장 호르몬 결합체의 신규 액상 제제
CN109380730B (zh) * 2017-08-09 2023-02-03 内蒙古伊利实业集团股份有限公司 微胶囊油脂及其制备方法
WO2019055539A1 (en) 2017-09-12 2019-03-21 Prudhomme Robert K CELLULOSIC POLYMER NANOPARTICLES AND METHODS OF FORMING THE SAME
JP2021501753A (ja) 2017-11-03 2021-01-21 ザ・トラスティーズ・オブ・プリンストン・ユニバーシティＴｈｅ Ｔｒｕｓｔｅｅｓ Ｏｆ Ｐｒｉｎｃｅｔｏｎ Ｕｎｉｖｅｒｓｉｔｙ 徐放性ナノキャリア製剤を形成するための疎水性イオン対化およびフラッシュナノ沈殿
WO2020018890A1 (en) 2018-07-19 2020-01-23 Prudhomme Robert K Triblock copolymer stabilizers for the formation of nanoparticles encapsulating soluble biologics, therapeutics, and imaging agents
US11731099B2 (en) 2018-07-20 2023-08-22 The Trustees Of Princeton University Method for controlling encapsulation efficiency and burst release of water soluble molecules from nanoparticles and microparticles produced by inverse flash nanoprecipitation
US20200147032A1 (en) 2018-11-14 2020-05-14 Robert K. Prud'homme Dihydromyricetin hot melt extrusion formulations and methods for forming them
MX2021015457A (es) 2019-06-14 2022-04-06 Univ Princeton Formulaciones de dihidromiricetina y un permeabilizante.
CN114240934B (zh) * 2022-02-21 2022-05-10 深圳大学 一种基于肢端肥大症的图像数据分析方法及系统
CN116571178B (zh) * 2023-05-11 2026-01-20 仲恺农业工程学院 一种蓝莓花色苷微胶囊的制备方法和应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6068044A (ja) * 1983-09-24 1985-04-18 Tetsuo Kato 二重膜構造のマイクロカプセル
ATE90203T1 (de) * 1989-03-17 1993-06-15 Pitman Moore Inc Kontrollierte, verzoegerte wirkstofffreisetzung von makromolekularen proteinen.
US5219572A (en) * 1989-03-17 1993-06-15 Pitman-Moore, Inc. Controlled release delivery device for macromolecular proteins
ATE364442T1 (de) * 2000-04-27 2007-07-15 Verion Inc Nullte-ordnung-freisetzung und temperatur- kontrollierte mikrokapseln sowie herstellungsverfahren
US6967028B2 (en) * 2000-07-31 2005-11-22 Mainelab Prolonged release microspheres for injectable administration
FR2820319B3 (fr) * 2001-02-08 2003-12-05 Ellipse Pharmaceuticals Procede de fabrication d'un comprime flottant incluant de l'alfuzosine et comprime obtenu
EP1595549A4 (en) * 2003-02-19 2010-09-22 Takeda Pharmaceutical DISPERSE FOR PREPARATIONS WITH DELAYED RELEASE
KR20090046773A (ko) * 2006-06-05 2009-05-11 오션 뉴트리션 캐나다 리미티드 개선된 쉘을 가지는 마이크로캡슐
US8729015B2 (en) 2007-12-21 2014-05-20 Merck Patent Gmbh Solid lipid microcapsules containing growth hormone inner core microparticles

Also Published As

Publication number Publication date
EA201001002A1 (ru) 2011-06-30
CN101903014B (zh) 2014-04-16
EP2231120A1 (en) 2010-09-29
KR20100103846A (ko) 2010-09-28
IL206393A0 (en) 2010-12-30
CA2710062C (en) 2016-05-31
BRPI0821359A2 (pt) 2015-06-16
IL206393A (en) 2015-06-30
JP2011506499A (ja) 2011-03-03
US20100310649A1 (en) 2010-12-09
EP2231120B1 (en) 2011-06-29
AU2008340785A1 (en) 2009-07-02
CA2710062A1 (en) 2009-07-02
AU2008340785B8 (en) 2014-09-18
AU2008340785B2 (en) 2014-05-08
CN101903014A (zh) 2010-12-01
US8729015B2 (en) 2014-05-20
ATE514417T1 (de) 2011-07-15
ZA201005167B (en) 2011-03-30
WO2009080164A1 (en) 2009-07-02
JP5773651B2 (ja) 2015-09-02
ES2367093T3 (es) 2011-10-28

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