CA2710062C - Solid lipid microcapsules containing growth hormone in the inner solid core - Google Patents
Solid lipid microcapsules containing growth hormone in the inner solid core Download PDFInfo
- Publication number
- CA2710062C CA2710062C CA2710062A CA2710062A CA2710062C CA 2710062 C CA2710062 C CA 2710062C CA 2710062 A CA2710062 A CA 2710062A CA 2710062 A CA2710062 A CA 2710062A CA 2710062 C CA2710062 C CA 2710062C
- Authority
- CA
- Canada
- Prior art keywords
- microcapsules according
- lipid
- hgh
- microcapsules
- growth hormone
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Endocrinology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Diabetes (AREA)
- General Chemical & Material Sciences (AREA)
- Dispersion Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP07024906.5 | 2007-12-21 | ||
| EP07024906 | 2007-12-21 | ||
| PCT/EP2008/009849 WO2009080164A1 (en) | 2007-12-21 | 2008-11-21 | Solid lipid microcapsules containing growth hormone in the inner solid core |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2710062A1 CA2710062A1 (en) | 2009-07-02 |
| CA2710062C true CA2710062C (en) | 2016-05-31 |
Family
ID=40566364
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2710062A Expired - Fee Related CA2710062C (en) | 2007-12-21 | 2008-11-21 | Solid lipid microcapsules containing growth hormone in the inner solid core |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US8729015B2 (enExample) |
| EP (1) | EP2231120B1 (enExample) |
| JP (1) | JP5773651B2 (enExample) |
| KR (1) | KR20100103846A (enExample) |
| CN (1) | CN101903014B (enExample) |
| AR (1) | AR069844A1 (enExample) |
| AT (1) | ATE514417T1 (enExample) |
| AU (1) | AU2008340785B8 (enExample) |
| BR (1) | BRPI0821359A2 (enExample) |
| CA (1) | CA2710062C (enExample) |
| EA (1) | EA201001002A1 (enExample) |
| ES (1) | ES2367093T3 (enExample) |
| IL (1) | IL206393A (enExample) |
| WO (1) | WO2009080164A1 (enExample) |
| ZA (1) | ZA201005167B (enExample) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BRPI0821359A2 (pt) | 2007-12-21 | 2015-06-16 | Merck Patent Ges Mit Beschränkter Haftung | Microcápsulas de lipídeos sólidas contendo hormônio de crescimento no núcleo sólido interno |
| WO2010017965A2 (en) * | 2008-08-11 | 2010-02-18 | Merck Serono S.A. | SOLID LIPID MICROCAPSULES CONTAINING hGH |
| CN102370630B (zh) * | 2010-08-11 | 2014-04-02 | 中国科学院过程工程研究所 | 重组人生长激素rhGH长效缓释微囊及其制备方法 |
| ES2810003T3 (es) | 2011-11-18 | 2021-03-08 | Regeneron Pharma | Micropartícula que contiene proteína terapéutica recubierta con polímero biodegradable para uso médico |
| JP6554493B2 (ja) | 2014-06-24 | 2019-07-31 | ザ・トラスティーズ・オブ・プリンストン・ユニバーシティＴｈｅ Ｔｒｕｓｔｅｅｓ Ｏｆ Ｐｒｉｎｃｅｔｏｎ Ｕｎｉｖｅｒｓｉｔｙ | 可溶性生物製剤、治療薬およびイメージング剤をカプセル化するためのプロセス |
| KR101602138B1 (ko) | 2014-11-21 | 2016-03-10 | 강원대학교산학협력단 | 염화칼슘 미세입자가 봉입된 온도 의존성 고체지질입자 및 그 제조방법 |
| US11103461B2 (en) | 2015-12-22 | 2021-08-31 | The Trustees Of Princeton University | Process for encapsulating soluble biologics, therapeutics, and imaging agents |
| KR20170079409A (ko) * | 2015-12-30 | 2017-07-10 | 한미약품 주식회사 | 지속형 인간 성장 호르몬 결합체의 신규 액상 제제 |
| CN109380730B (zh) * | 2017-08-09 | 2023-02-03 | 内蒙古伊利实业集团股份有限公司 | 微胶囊油脂及其制备方法 |
| WO2019055539A1 (en) | 2017-09-12 | 2019-03-21 | Prudhomme Robert K | CELLULOSIC POLYMER NANOPARTICLES AND METHODS OF FORMING THE SAME |
| JP2021501753A (ja) | 2017-11-03 | 2021-01-21 | ザ・トラスティーズ・オブ・プリンストン・ユニバーシティＴｈｅ Ｔｒｕｓｔｅｅｓ Ｏｆ Ｐｒｉｎｃｅｔｏｎ Ｕｎｉｖｅｒｓｉｔｙ | 徐放性ナノキャリア製剤を形成するための疎水性イオン対化およびフラッシュナノ沈殿 |
| US12186436B2 (en) | 2018-07-19 | 2025-01-07 | The Trustees Of Princeton University | Triblock copolymer stabilizers for the formation of nanoparticles encapsulating soluble biologics, therapeutics, and imaging agents |
| US11731099B2 (en) | 2018-07-20 | 2023-08-22 | The Trustees Of Princeton University | Method for controlling encapsulation efficiency and burst release of water soluble molecules from nanoparticles and microparticles produced by inverse flash nanoprecipitation |
| US20200147032A1 (en) | 2018-11-14 | 2020-05-14 | Robert K. Prud'homme | Dihydromyricetin hot melt extrusion formulations and methods for forming them |
| CN114240934B (zh) * | 2022-02-21 | 2022-05-10 | 深圳大学 | 一种基于肢端肥大症的图像数据分析方法及系统 |
| CN116571178A (zh) * | 2023-05-11 | 2023-08-11 | 仲恺农业工程学院 | 一种蓝莓花色苷微胶囊的制备方法和应用 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6068044A (ja) * | 1983-09-24 | 1985-04-18 | Tetsuo Kato | 二重膜構造のマイクロカプセル |
| ATE90203T1 (de) * | 1989-03-17 | 1993-06-15 | Pitman Moore Inc | Kontrollierte, verzoegerte wirkstofffreisetzung von makromolekularen proteinen. |
| US5219572A (en) * | 1989-03-17 | 1993-06-15 | Pitman-Moore, Inc. | Controlled release delivery device for macromolecular proteins |
| AU2001257359A1 (en) * | 2000-04-27 | 2001-11-07 | Verion Inc. | Zero order release and temperature-controlled microcapsules and process for the preparation thereof |
| US6967028B2 (en) * | 2000-07-31 | 2005-11-22 | Mainelab | Prolonged release microspheres for injectable administration |
| FR2820319B3 (fr) * | 2001-02-08 | 2003-12-05 | Ellipse Pharmaceuticals | Procede de fabrication d'un comprime flottant incluant de l'alfuzosine et comprime obtenu |
| EP1595549A4 (en) * | 2003-02-19 | 2010-09-22 | Takeda Pharmaceutical | DISPERSE FOR PREPARATIONS WITH DELAYED RELEASE |
| PL2040682T3 (pl) * | 2006-06-05 | 2018-01-31 | Dsm Nutritional Products Ag | Mikrokapsułki o ulepszonych otoczkach |
| BRPI0821359A2 (pt) | 2007-12-21 | 2015-06-16 | Merck Patent Ges Mit Beschränkter Haftung | Microcápsulas de lipídeos sólidas contendo hormônio de crescimento no núcleo sólido interno |
-
2008
- 2008-11-21 BR BRPI0821359-3A patent/BRPI0821359A2/pt not_active IP Right Cessation
- 2008-11-21 EA EA201001002A patent/EA201001002A1/ru unknown
- 2008-11-21 KR KR1020107016389A patent/KR20100103846A/ko not_active Withdrawn
- 2008-11-21 EP EP08864968A patent/EP2231120B1/en not_active Not-in-force
- 2008-11-21 JP JP2010538383A patent/JP5773651B2/ja not_active Expired - Fee Related
- 2008-11-21 AT AT08864968T patent/ATE514417T1/de not_active IP Right Cessation
- 2008-11-21 WO PCT/EP2008/009849 patent/WO2009080164A1/en not_active Ceased
- 2008-11-21 US US12/809,397 patent/US8729015B2/en not_active Expired - Fee Related
- 2008-11-21 CA CA2710062A patent/CA2710062C/en not_active Expired - Fee Related
- 2008-11-21 CN CN200880121661.2A patent/CN101903014B/zh not_active Expired - Fee Related
- 2008-11-21 ES ES08864968T patent/ES2367093T3/es active Active
- 2008-11-21 AU AU2008340785A patent/AU2008340785B8/en not_active Ceased
- 2008-12-19 AR ARP080105563A patent/AR069844A1/es unknown
-
2010
- 2010-06-15 IL IL206393A patent/IL206393A/en not_active IP Right Cessation
- 2010-07-20 ZA ZA2010/05167A patent/ZA201005167B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU2008340785A1 (en) | 2009-07-02 |
| EA201001002A1 (ru) | 2011-06-30 |
| EP2231120A1 (en) | 2010-09-29 |
| EP2231120B1 (en) | 2011-06-29 |
| WO2009080164A1 (en) | 2009-07-02 |
| ES2367093T3 (es) | 2011-10-28 |
| CN101903014A (zh) | 2010-12-01 |
| CA2710062A1 (en) | 2009-07-02 |
| ZA201005167B (en) | 2011-03-30 |
| JP2011506499A (ja) | 2011-03-03 |
| IL206393A (en) | 2015-06-30 |
| BRPI0821359A2 (pt) | 2015-06-16 |
| AR069844A1 (es) | 2010-02-24 |
| CN101903014B (zh) | 2014-04-16 |
| ATE514417T1 (de) | 2011-07-15 |
| US20100310649A1 (en) | 2010-12-09 |
| AU2008340785B2 (en) | 2014-05-08 |
| US8729015B2 (en) | 2014-05-20 |
| IL206393A0 (en) | 2010-12-30 |
| AU2008340785B8 (en) | 2014-09-18 |
| JP5773651B2 (ja) | 2015-09-02 |
| KR20100103846A (ko) | 2010-09-28 |
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Legal Events
| Date | Code | Title | Description |
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| EEER | Examination request |
Effective date: 20131121 |
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| MKLA | Lapsed |
Effective date: 20191121 |