AR063366A1 - Suspensiones farmaceuticas acuosas que contienen rebamipide y su proceso de fabricacion - Google Patents
Suspensiones farmaceuticas acuosas que contienen rebamipide y su proceso de fabricacionInfo
- Publication number
- AR063366A1 AR063366A1 ARP070104698A ARP070104698A AR063366A1 AR 063366 A1 AR063366 A1 AR 063366A1 AR P070104698 A ARP070104698 A AR P070104698A AR P070104698 A ARP070104698 A AR P070104698A AR 063366 A1 AR063366 A1 AR 063366A1
- Authority
- AR
- Argentina
- Prior art keywords
- rebamipide
- manufacturing process
- containing rebamipide
- pharmaceutical suspensions
- waterproof containing
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4704—2-Quinolinones, e.g. carbostyril
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/04—Artificial tears; Irrigation solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dispersion Chemistry (AREA)
- Ophthalmology & Optometry (AREA)
- Otolaryngology (AREA)
- Pulmonology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Suspension farmacéutica acuosa que contiene rebamipide que se puede preparar por un proceso simple y mantener el estado de partículas finas dispersas de rebamipide estable sin presentar aglutinacion de las partículas finas. La suspension farmacéutica acuosa que contiene rebamipide de la presente se prepara por mezclado de alcohol polivinílico y además un compuesto que es un compuesto de tipo sal sodica con rebamipide.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2006291535 | 2006-10-26 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR063366A1 true AR063366A1 (es) | 2009-01-21 |
Family
ID=39324676
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP070104698A AR063366A1 (es) | 2006-10-26 | 2007-10-24 | Suspensiones farmaceuticas acuosas que contienen rebamipide y su proceso de fabricacion |
Country Status (20)
Country | Link |
---|---|
US (1) | US8772317B2 (es) |
EP (1) | EP2077840A4 (es) |
JP (1) | JP5250551B2 (es) |
KR (2) | KR20090073248A (es) |
CN (1) | CN101528229B (es) |
AR (1) | AR063366A1 (es) |
AU (1) | AU2007309968B2 (es) |
BR (1) | BRPI0718429A2 (es) |
CA (1) | CA2665024C (es) |
HK (1) | HK1133188A1 (es) |
IL (1) | IL197950A0 (es) |
MX (1) | MX2009004433A (es) |
MY (1) | MY148303A (es) |
NZ (1) | NZ576224A (es) |
RU (1) | RU2467751C2 (es) |
SG (1) | SG175628A1 (es) |
TW (1) | TWI415629B (es) |
UA (1) | UA95989C2 (es) |
WO (1) | WO2008050896A1 (es) |
ZA (1) | ZA200902778B (es) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TW200808375A (en) | 2006-05-12 | 2008-02-16 | Otsuka Pharma Co Ltd | Hydrogel suspension and manufacturing process thereof |
CA2725487A1 (en) * | 2008-06-19 | 2009-12-23 | Otsuka Pharmaceutical Co., Ltd. | A pharmaceutical composition |
WO2012128394A1 (en) * | 2011-03-24 | 2012-09-27 | Otsuka Pharmaceutical Co., Ltd. | A pharmaceutical composition for treating a disease in the oral cavity comprising rebamipide |
CN102240260B (zh) * | 2011-05-17 | 2012-05-23 | 山东省医疗器械研究所 | 一种治疗阴道干涩症的药物及其制备方法 |
TW201322982A (zh) | 2011-11-01 | 2013-06-16 | Otsuka Pharma Co Ltd | 用於治療前眼疾病之藥劑,該藥劑包含瑞巴派特及眼淚保持劑 |
DK2814514T3 (en) * | 2012-02-16 | 2017-12-18 | Atyr Pharma Inc | Histidyl tRNA synthetases for the treatment of autoimmune and inflammatory diseases |
AR090775A1 (es) * | 2012-04-23 | 2014-12-03 | Otsuka Pharma Co Ltd | Preparado inyectable |
WO2015034008A1 (ja) * | 2013-09-05 | 2015-03-12 | 大塚製薬株式会社 | レバミピドの局所止血用途 |
CN104586762A (zh) * | 2014-04-11 | 2015-05-06 | 广州仁恒医药科技有限公司 | 含有瑞巴派特的药物组合物及其制备方法 |
CN103976946A (zh) * | 2014-05-20 | 2014-08-13 | 广州艾格生物科技有限公司 | 一种含有水溶性高分子聚合物的瑞巴派特混悬滴眼液及其制备方法 |
JP6854587B2 (ja) * | 2015-04-17 | 2021-04-07 | ロート製薬株式会社 | 医薬製剤 |
US20180161438A1 (en) * | 2015-05-28 | 2018-06-14 | Rohto Pharmaceutical Co., Ltd. | Aqueous Ophthalmic Composition |
CN105147606A (zh) * | 2015-08-18 | 2015-12-16 | 广州仁恒医药科技有限公司 | 一种瑞巴派特水悬浮液的制备方法 |
KR101718733B1 (ko) | 2015-08-21 | 2017-03-22 | 국제약품 주식회사 | 레바미피드의 가용화 방법 및 이에 의해 제조된 안구건조증 치료용 액제 |
KR102307958B1 (ko) | 2015-10-01 | 2021-10-05 | 삼진제약주식회사 | 레바미피드를 함유하는 신규한 점안 조성물 및 이의 제조방법 |
KR20170039347A (ko) | 2015-10-01 | 2017-04-11 | 삼진제약주식회사 | 레바미피드를 함유하는 신규한 점안 조성물 및 이의 제조방법 |
JP2017109996A (ja) * | 2015-12-11 | 2017-06-22 | 日本合成化学工業株式会社 | 結晶成長抑制剤 |
CN107349181B (zh) * | 2016-05-09 | 2021-02-19 | 四川科伦药物研究院有限公司 | 含有瑞巴派特和聚维酮的眼科水悬浮液及其制备方法 |
KR101923519B1 (ko) * | 2018-06-26 | 2019-02-27 | 대우제약 주식회사 | 레바미피드를 함유하는 안구 건조증 치료용 수용성 다회용 점안제 조성물 및 이의 가용화 및 안정화 방법 |
KR20200019451A (ko) | 2018-08-14 | 2020-02-24 | 대우제약 주식회사 | 레바미피드를 함유하는 안구 건조증 치료용 수용성 다회용 점안제 조성물 및 이의 가용화 및 안정화 방법 |
Family Cites Families (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0313000B1 (de) * | 1987-10-21 | 1998-05-06 | Siemens Aktiengesellschaft | Verfahren zum Herstellen eines Bipolartransistors mit isolierter Gateelektrode |
US5188826A (en) * | 1988-02-08 | 1993-02-23 | Insite Vision Incorporated | Topical ophthalmic suspensions |
RU2098094C1 (ru) * | 1991-03-27 | 1997-12-10 | Сендзю Фармасьютикал Ко., Лтд. | Способ приготовления водной суспензии и водный глазной препарат |
US5540930A (en) | 1993-10-25 | 1996-07-30 | Pharmos Corporation | Suspension of loteprednol etabonate for ear, eye, or nose treatment |
US5556848A (en) | 1993-12-27 | 1996-09-17 | Senju Pharmaceutical Co., Ltd. | Ophthalmic suspension containing diflupredonate |
JP3781792B2 (ja) | 1993-12-27 | 2006-05-31 | 千寿製薬株式会社 | ジフルプレドナート含有点眼用懸濁液剤 |
US5576311A (en) | 1994-11-30 | 1996-11-19 | Pharmos Corporation | Cyclodextrins as suspending agents for pharmaceutical suspensions |
JP3093661B2 (ja) * | 1995-10-12 | 2000-10-03 | 大塚製薬株式会社 | 眼疾患治療剤 |
AR004214A1 (es) * | 1995-10-12 | 1998-11-04 | Otsuka Pharma Co Ltd | Una preparación de gotas oftálmicas para la cura de enfermedades oftálmicas |
US6489346B1 (en) * | 1996-01-04 | 2002-12-03 | The Curators Of The University Of Missouri | Substituted benzimidazole dosage forms and method of using same |
KR20010012188A (ko) * | 1997-05-14 | 2001-02-15 | 요시다 쇼지 | 재분산성이 양호한 수성 현탁액제 |
JP3402195B2 (ja) * | 1997-05-14 | 2003-04-28 | 千寿製薬株式会社 | 再分散性の良い水性懸濁液剤 |
CN1813699B (zh) * | 2001-06-14 | 2012-04-18 | 大塚制药株式会社 | 药物组合物 |
US20050255144A1 (en) * | 2003-04-09 | 2005-11-17 | Directcontact Llc | Methods and articles for the delivery of medicaments to the eye for the treatment of posterior segment diseases |
JP2005008625A (ja) | 2003-05-23 | 2005-01-13 | Santen Pharmaceut Co Ltd | キノロン系抗菌化合物を含有する点眼液 |
EP1627637A1 (en) | 2003-05-23 | 2006-02-22 | Santen Pharmaceutical Co., Ltd. | Ophthalmic solution containing quinolone antimicrobial compound |
TW200613006A (en) | 2004-09-10 | 2006-05-01 | Otsuka Pharma Co Ltd | Rebamipide preparation for rectal administration to be prepared before using |
TWI363626B (en) * | 2004-11-15 | 2012-05-11 | Otsuka Pharma Co Ltd | Aqueous ophthalmic suspension of crystalline rebamipide |
TW200808375A (en) | 2006-05-12 | 2008-02-16 | Otsuka Pharma Co Ltd | Hydrogel suspension and manufacturing process thereof |
-
2007
- 2007-10-01 TW TW096136705A patent/TWI415629B/zh not_active IP Right Cessation
- 2007-10-24 CA CA2665024A patent/CA2665024C/en not_active Expired - Fee Related
- 2007-10-24 AU AU2007309968A patent/AU2007309968B2/en not_active Ceased
- 2007-10-24 WO PCT/JP2007/071167 patent/WO2008050896A1/en active Application Filing
- 2007-10-24 RU RU2009119717/15A patent/RU2467751C2/ru not_active IP Right Cessation
- 2007-10-24 BR BRPI0718429-8A2A patent/BRPI0718429A2/pt not_active IP Right Cessation
- 2007-10-24 JP JP2009518660A patent/JP5250551B2/ja active Active
- 2007-10-24 KR KR1020097010624A patent/KR20090073248A/ko not_active Application Discontinuation
- 2007-10-24 NZ NZ576224A patent/NZ576224A/en unknown
- 2007-10-24 CN CN2007800400591A patent/CN101528229B/zh active Active
- 2007-10-24 SG SG2011074945A patent/SG175628A1/en unknown
- 2007-10-24 AR ARP070104698A patent/AR063366A1/es unknown
- 2007-10-24 KR KR1020147016857A patent/KR101491965B1/ko active IP Right Grant
- 2007-10-24 MY MYPI20091347A patent/MY148303A/en unknown
- 2007-10-24 EP EP07830901A patent/EP2077840A4/en not_active Withdrawn
- 2007-10-24 US US12/447,065 patent/US8772317B2/en not_active Expired - Fee Related
- 2007-10-24 MX MX2009004433A patent/MX2009004433A/es active IP Right Grant
- 2007-10-24 UA UAA200905226A patent/UA95989C2/uk unknown
-
2009
- 2009-04-05 IL IL197950A patent/IL197950A0/en not_active IP Right Cessation
- 2009-04-16 ZA ZA2009/02778A patent/ZA200902778B/en unknown
- 2009-12-02 HK HK09111298.7A patent/HK1133188A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
US8772317B2 (en) | 2014-07-08 |
KR101491965B1 (ko) | 2015-02-10 |
JP2010507566A (ja) | 2010-03-11 |
AU2007309968A1 (en) | 2008-05-02 |
RU2467751C2 (ru) | 2012-11-27 |
UA95989C2 (uk) | 2011-09-26 |
CN101528229A (zh) | 2009-09-09 |
SG175628A1 (en) | 2011-11-28 |
RU2009119717A (ru) | 2010-12-10 |
EP2077840A4 (en) | 2010-08-11 |
TW200822936A (en) | 2008-06-01 |
CA2665024C (en) | 2015-04-07 |
KR20140088228A (ko) | 2014-07-09 |
BRPI0718429A2 (pt) | 2013-11-12 |
US20100029714A1 (en) | 2010-02-04 |
MY148303A (en) | 2013-03-29 |
KR20090073248A (ko) | 2009-07-02 |
EP2077840A1 (en) | 2009-07-15 |
MX2009004433A (es) | 2009-05-08 |
NZ576224A (en) | 2010-12-24 |
CA2665024A1 (en) | 2008-05-02 |
ZA200902778B (en) | 2010-02-24 |
JP5250551B2 (ja) | 2013-07-31 |
AU2007309968B2 (en) | 2012-09-06 |
WO2008050896A1 (en) | 2008-05-02 |
CN101528229B (zh) | 2012-07-04 |
TWI415629B (zh) | 2013-11-21 |
HK1133188A1 (en) | 2010-03-19 |
IL197950A0 (en) | 2009-12-24 |
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Legal Events
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