AR056082A1 - Formas cristalinas de clorhidrato de irinotecano (monoclorhidrato de 7-etil-10-[4-(1-piperidin)-1-piperidin]carboniloxicamptotecina trihidratado) y metodos de preparacion de las mismas - Google Patents

Formas cristalinas de clorhidrato de irinotecano (monoclorhidrato de 7-etil-10-[4-(1-piperidin)-1-piperidin]carboniloxicamptotecina trihidratado) y metodos de preparacion de las mismas

Info

Publication number
AR056082A1
AR056082A1 ARP060104123A ARP060104123A AR056082A1 AR 056082 A1 AR056082 A1 AR 056082A1 AR P060104123 A ARP060104123 A AR P060104123A AR P060104123 A ARP060104123 A AR P060104123A AR 056082 A1 AR056082 A1 AR 056082A1
Authority
AR
Argentina
Prior art keywords
crystalline form
irinotecan hydrochloride
hydrochloric acid
piperidin
ethanol
Prior art date
Application number
ARP060104123A
Other languages
English (en)
Spanish (es)
Inventor
Shu-Ping Chen
Piin-Jye Harn
Original Assignee
Scinopharm Singapore Pte Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scinopharm Singapore Pte Ltd filed Critical Scinopharm Singapore Pte Ltd
Publication of AR056082A1 publication Critical patent/AR056082A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
ARP060104123A 2005-09-20 2006-09-21 Formas cristalinas de clorhidrato de irinotecano (monoclorhidrato de 7-etil-10-[4-(1-piperidin)-1-piperidin]carboniloxicamptotecina trihidratado) y metodos de preparacion de las mismas AR056082A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US71882705P 2005-09-20 2005-09-20

Publications (1)

Publication Number Publication Date
AR056082A1 true AR056082A1 (es) 2007-09-19

Family

ID=37889452

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP060104123A AR056082A1 (es) 2005-09-20 2006-09-21 Formas cristalinas de clorhidrato de irinotecano (monoclorhidrato de 7-etil-10-[4-(1-piperidin)-1-piperidin]carboniloxicamptotecina trihidratado) y metodos de preparacion de las mismas

Country Status (14)

Country Link
US (1) US7435818B2 (enExample)
EP (2) EP2082741A1 (enExample)
JP (1) JP5119153B2 (enExample)
KR (1) KR101150504B1 (enExample)
CN (1) CN101277694B (enExample)
AR (1) AR056082A1 (enExample)
AT (1) ATE460162T1 (enExample)
AU (1) AU2006292328B2 (enExample)
BR (1) BRPI0616308A2 (enExample)
CA (1) CA2623117C (enExample)
DE (1) DE602006012871D1 (enExample)
ES (1) ES2343204T3 (enExample)
NZ (1) NZ566807A (enExample)
WO (1) WO2007035709A2 (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101318964B (zh) * 2007-06-07 2010-12-15 上海迪赛诺医药发展有限公司 盐酸伊立替康新晶型及其制备方法
US7572803B2 (en) * 2007-10-25 2009-08-11 The Christus Stehlin Foundation For Cancer Research Hydrated crystalline esters of camptothecin
IT1391757B1 (it) * 2008-11-11 2012-01-27 Antibioticos Spa Irinotecan cloridrato cristallino e metodi per la sua preparazione
US8546573B2 (en) 2009-11-18 2013-10-01 Cadila Healthcare Limited Process for the preparation of 7-ethyl-10-[4-(1-piperidino)-1-piperdino] carbonyloxy-camptothecin hydrochloride trihydrate
WO2012007952A1 (en) * 2010-07-12 2012-01-19 Hetero Research Foundation Novel polymorph of irinotecan hydrochloride
CN102311443B (zh) * 2011-08-24 2014-07-16 上海北卡医药技术有限公司 盐酸伊立替康的新晶型及其制备方法
CN102617584B (zh) * 2012-03-14 2013-10-16 海南锦瑞制药股份有限公司 一种盐酸伊立替康化合物及其药物组合物
CN102850363B (zh) * 2012-09-18 2013-07-10 山东罗欣药业股份有限公司 盐酸伊立替康化合物及其药物组合物
CA2909642A1 (en) * 2013-04-15 2014-10-23 Regeneron Pharmaceuticals, Inc. Markers of tumor cell response to anti-cancer therapy
CN105713004A (zh) * 2016-03-23 2016-06-29 杭州华东医药集团新药研究院有限公司 一种高品质盐酸伊立替康三水合物晶型的制备方法
US10919905B2 (en) * 2019-05-16 2021-02-16 Scinopharm Taiwan, Ltd. Polymorphism for irinotecan free base

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6019790A (ja) 1983-07-14 1985-01-31 Yakult Honsha Co Ltd 新規なカンプトテシン誘導体
MA24682A1 (fr) * 1997-10-23 1999-07-01 Smithkline Beecham Corp Formes polymorphes nouvelles de cipamfylline, procede pour leur preparation et compositions les contenant
AU2930501A (en) * 2000-01-07 2001-07-24 Transform Pharmaceuticals, Inc. High-throughput formation, identification, and analysis of diverse solid-forms
DE60314378T2 (de) * 2002-03-01 2008-02-28 Pfizer Italia S.R.L. Kristalline polymorphe form von irinotecanhydrochlorid
CZ20022250A3 (cs) * 2002-06-27 2004-02-18 Pliva-Lachema A. S. Způsob výroby irinotekanu
KR101095382B1 (ko) 2003-02-25 2011-12-16 가부시키가이샤 야쿠르트 혼샤 이리노테칸 염산염의 결정다형의 제조방법
WO2006016203A1 (en) * 2004-08-09 2006-02-16 Shilpa Medicare Limited An improved process for the preparation of irinotecan hydrochloride trihydrate
US20060046993A1 (en) * 2004-09-01 2006-03-02 Pharmacia Italia S.P.A. Crystalline polymorphic form of irinotecan hydrochloride
EP1846412B1 (en) * 2005-02-07 2009-10-21 Fermion Oy Process for the manufacturing of 7-ethyl-10-hydroxy camptothecin
JP5133704B2 (ja) * 2005-02-08 2013-01-30 フェルミオン オサケ ユキチュア 製造方法

Also Published As

Publication number Publication date
CN101277694A (zh) 2008-10-01
EP1951235B1 (en) 2010-03-10
EP2082741A1 (en) 2009-07-29
BRPI0616308A2 (pt) 2011-06-14
ES2343204T3 (es) 2010-07-26
AU2006292328A1 (en) 2007-03-29
CA2623117A1 (en) 2007-03-29
CN101277694B (zh) 2011-04-20
JP2009508874A (ja) 2009-03-05
NZ566807A (en) 2011-05-27
JP5119153B2 (ja) 2013-01-16
WO2007035709A2 (en) 2007-03-29
US20070072890A1 (en) 2007-03-29
KR20080059244A (ko) 2008-06-26
AU2006292328B2 (en) 2012-12-20
EP1951235A4 (en) 2008-10-29
WO2007035709A3 (en) 2007-10-25
CA2623117C (en) 2013-12-10
EP1951235A2 (en) 2008-08-06
ATE460162T1 (de) 2010-03-15
US7435818B2 (en) 2008-10-14
DE602006012871D1 (de) 2010-04-22
KR101150504B1 (ko) 2012-07-09

Similar Documents

Publication Publication Date Title
AR129907A2 (es) FORMA CRISTALINA DEL HEMIHIDRATO DE 1-(b-D-GLUCOPIRANOSIL)-4-METIL-3-[5-(4-FLUOROFENIL)-2-TIENILMETIL]BENCENO, COMPOSICIÓN FARMACÉUTICA, PROCESO PARA LA PREPARACIÓN Y USOS
AR056082A1 (es) Formas cristalinas de clorhidrato de irinotecano (monoclorhidrato de 7-etil-10-[4-(1-piperidin)-1-piperidin]carboniloxicamptotecina trihidratado) y metodos de preparacion de las mismas
MY141194A (en) Process for the synthesis of ivabradine and its pharmaceutically acceptable acid addition salts
WO2007047863A3 (en) Crystals of laquinimod sodium, and process for the manufacture thereof
PH12014500673A1 (en) Method for producing glufosinate p free acid
AR062134A1 (es) Erlotinib cristalino
BRPI0410760A (pt) compostos, processo para fabricação dos mesmos, composições farmacêuticas e uso deste compostos
SI1598333T1 (sl) Postopek za pripravo (1s)-4,5-dimetoksi-1-(metilaminometil)-benzociklobutana in njegovih adicijskih soli, kot tudi uporaba za sintezo ivabradina in njegovih adicijskih soli s farmacevtsko sprejemljivo kislino
GEP20115343B (en) New method for preparing functionalised benzocyclo-butenes and its application to the synthesis of ivabradine and its addition salts with a pharmaceutically acceptable acid
NZ602450A (en) Agomelatine hydrochloride hydrate and preparation thereof
BRPI0413393A (pt) fexofenadina, composição farmaceuticamente aceitável, método de tratamento antihistamìnico, composição, processo para preparar fexofenadina e uso de fexofenadina
AR080275A1 (es) Formas solidas de un derivado de n-( fenilmetil) propanamida y procedimientos de preparacion
JP2010512333A5 (enExample)
CN103864760B (zh) 一种盐酸法舒地尔化合物
WO2009122303A3 (en) Novel mandelate salt of fesoterodine
WO2008099286A3 (en) Improved process for preparing ethyl (s)-2-ethoxy-4-[n-[1-(2- piperidinophenyl)-3-methyl-1-butyl]aminocarbonyl methyl]benzoate and use thereof for the preparation of repaglinide
WO2008034912A3 (en) Process for the synthesis of clopidogrel and new forms of pharmaceutically acceptable salts thereof
AR081514A1 (es) El compuesto 4-[etil(dimetil)amonio]butanoato, el metodo para la preparacion del mismo y el uso en el tratamiento de la enfermedad cardiovascular
RU2019106531A (ru) Кристалл соли производного хиназолина
ATE528301T1 (de) Verfahren zur herstellung von substituierten sulfoxidzusammensetzungen
WO2009084039A3 (en) Process for producing 1-[2-(dimethylamino)-1-(4-phenol)ethyl]cyclohexanol
CN102977039B (zh) 6-氟-3-羟基-2-吡嗪甲酰胺α晶型及其制备方法
CN107827819A (zh) 一种喷他佐辛晶型及其制备方法
AR081219A1 (es) Preparacion de clorhidrato de ezatiostat cristalino ansolvatado forma d
WO2009056617A3 (en) 4,4-disubstituted piperdines as renin inhibitors

Legal Events

Date Code Title Description
FB Suspension of granting procedure