DE602006012871D1 - Neue kristallformen von irinotecan-hydrochlorid - Google Patents

Neue kristallformen von irinotecan-hydrochlorid

Info

Publication number
DE602006012871D1
DE602006012871D1 DE602006012871T DE602006012871T DE602006012871D1 DE 602006012871 D1 DE602006012871 D1 DE 602006012871D1 DE 602006012871 T DE602006012871 T DE 602006012871T DE 602006012871 T DE602006012871 T DE 602006012871T DE 602006012871 D1 DE602006012871 D1 DE 602006012871D1
Authority
DE
Germany
Prior art keywords
crystal forms
irinotecan hydrochloride
new crystal
irinotecan
hydrochloride
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602006012871T
Other languages
German (de)
English (en)
Inventor
Shu-Ping Chen
Piin-Jye Harn
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Scinopharm Singapore Pte Ltd
Original Assignee
Scinopharm Singapore Pte Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scinopharm Singapore Pte Ltd filed Critical Scinopharm Singapore Pte Ltd
Publication of DE602006012871D1 publication Critical patent/DE602006012871D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DE602006012871T 2005-09-20 2006-09-19 Neue kristallformen von irinotecan-hydrochlorid Active DE602006012871D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US71882705P 2005-09-20 2005-09-20
PCT/US2006/036437 WO2007035709A2 (en) 2005-09-20 2006-09-19 Novel crystal forms of irinotecan hydrochloride

Publications (1)

Publication Number Publication Date
DE602006012871D1 true DE602006012871D1 (de) 2010-04-22

Family

ID=37889452

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602006012871T Active DE602006012871D1 (de) 2005-09-20 2006-09-19 Neue kristallformen von irinotecan-hydrochlorid

Country Status (14)

Country Link
US (1) US7435818B2 (enExample)
EP (2) EP2082741A1 (enExample)
JP (1) JP5119153B2 (enExample)
KR (1) KR101150504B1 (enExample)
CN (1) CN101277694B (enExample)
AR (1) AR056082A1 (enExample)
AT (1) ATE460162T1 (enExample)
AU (1) AU2006292328B2 (enExample)
BR (1) BRPI0616308A2 (enExample)
CA (1) CA2623117C (enExample)
DE (1) DE602006012871D1 (enExample)
ES (1) ES2343204T3 (enExample)
NZ (1) NZ566807A (enExample)
WO (1) WO2007035709A2 (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101318964B (zh) * 2007-06-07 2010-12-15 上海迪赛诺医药发展有限公司 盐酸伊立替康新晶型及其制备方法
US7572803B2 (en) * 2007-10-25 2009-08-11 The Christus Stehlin Foundation For Cancer Research Hydrated crystalline esters of camptothecin
IT1391757B1 (it) * 2008-11-11 2012-01-27 Antibioticos Spa Irinotecan cloridrato cristallino e metodi per la sua preparazione
US8546573B2 (en) 2009-11-18 2013-10-01 Cadila Healthcare Limited Process for the preparation of 7-ethyl-10-[4-(1-piperidino)-1-piperdino] carbonyloxy-camptothecin hydrochloride trihydrate
WO2012007952A1 (en) * 2010-07-12 2012-01-19 Hetero Research Foundation Novel polymorph of irinotecan hydrochloride
CN102311443B (zh) * 2011-08-24 2014-07-16 上海北卡医药技术有限公司 盐酸伊立替康的新晶型及其制备方法
CN102617584B (zh) * 2012-03-14 2013-10-16 海南锦瑞制药股份有限公司 一种盐酸伊立替康化合物及其药物组合物
CN102850363B (zh) * 2012-09-18 2013-07-10 山东罗欣药业股份有限公司 盐酸伊立替康化合物及其药物组合物
CA2909642A1 (en) * 2013-04-15 2014-10-23 Regeneron Pharmaceuticals, Inc. Markers of tumor cell response to anti-cancer therapy
CN105713004A (zh) * 2016-03-23 2016-06-29 杭州华东医药集团新药研究院有限公司 一种高品质盐酸伊立替康三水合物晶型的制备方法
US10919905B2 (en) * 2019-05-16 2021-02-16 Scinopharm Taiwan, Ltd. Polymorphism for irinotecan free base

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6019790A (ja) 1983-07-14 1985-01-31 Yakult Honsha Co Ltd 新規なカンプトテシン誘導体
MA24682A1 (fr) * 1997-10-23 1999-07-01 Smithkline Beecham Corp Formes polymorphes nouvelles de cipamfylline, procede pour leur preparation et compositions les contenant
AU2930501A (en) * 2000-01-07 2001-07-24 Transform Pharmaceuticals, Inc. High-throughput formation, identification, and analysis of diverse solid-forms
DE60314378T2 (de) * 2002-03-01 2008-02-28 Pfizer Italia S.R.L. Kristalline polymorphe form von irinotecanhydrochlorid
CZ20022250A3 (cs) * 2002-06-27 2004-02-18 Pliva-Lachema A. S. Způsob výroby irinotekanu
KR101095382B1 (ko) 2003-02-25 2011-12-16 가부시키가이샤 야쿠르트 혼샤 이리노테칸 염산염의 결정다형의 제조방법
WO2006016203A1 (en) * 2004-08-09 2006-02-16 Shilpa Medicare Limited An improved process for the preparation of irinotecan hydrochloride trihydrate
US20060046993A1 (en) * 2004-09-01 2006-03-02 Pharmacia Italia S.P.A. Crystalline polymorphic form of irinotecan hydrochloride
EP1846412B1 (en) * 2005-02-07 2009-10-21 Fermion Oy Process for the manufacturing of 7-ethyl-10-hydroxy camptothecin
JP5133704B2 (ja) * 2005-02-08 2013-01-30 フェルミオン オサケ ユキチュア 製造方法

Also Published As

Publication number Publication date
CN101277694A (zh) 2008-10-01
EP1951235B1 (en) 2010-03-10
EP2082741A1 (en) 2009-07-29
BRPI0616308A2 (pt) 2011-06-14
ES2343204T3 (es) 2010-07-26
AU2006292328A1 (en) 2007-03-29
CA2623117A1 (en) 2007-03-29
CN101277694B (zh) 2011-04-20
JP2009508874A (ja) 2009-03-05
NZ566807A (en) 2011-05-27
JP5119153B2 (ja) 2013-01-16
WO2007035709A2 (en) 2007-03-29
US20070072890A1 (en) 2007-03-29
KR20080059244A (ko) 2008-06-26
AU2006292328B2 (en) 2012-12-20
EP1951235A4 (en) 2008-10-29
WO2007035709A3 (en) 2007-10-25
AR056082A1 (es) 2007-09-19
CA2623117C (en) 2013-12-10
EP1951235A2 (en) 2008-08-06
ATE460162T1 (de) 2010-03-15
US7435818B2 (en) 2008-10-14
KR101150504B1 (ko) 2012-07-09

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Legal Events

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