AR044070A1 - Derivados de 2 -acilamino -4- feniltiazol, su preparacion y su aplicacion en terapeutica - Google Patents
Derivados de 2 -acilamino -4- feniltiazol, su preparacion y su aplicacion en terapeuticaInfo
- Publication number
- AR044070A1 AR044070A1 ARP040101382A ARP040101382A AR044070A1 AR 044070 A1 AR044070 A1 AR 044070A1 AR P040101382 A ARP040101382 A AR P040101382A AR P040101382 A ARP040101382 A AR P040101382A AR 044070 A1 AR044070 A1 AR 044070A1
- Authority
- AR
- Argentina
- Prior art keywords
- alk
- group
- alkyl
- conr4
- formula
- Prior art date
Links
- 239000003814 drug Substances 0.000 title 1
- -1 trifluoromethoxy, trifluoroethoxy group Chemical group 0.000 abstract 13
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 6
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 5
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 4
- 125000000719 pyrrolidinyl group Chemical group 0.000 abstract 3
- ZHNUHDYFZUAESO-UHFFFAOYSA-N Formamide Chemical compound NC=O ZHNUHDYFZUAESO-UHFFFAOYSA-N 0.000 abstract 2
- 125000005336 allyloxy group Chemical group 0.000 abstract 2
- 125000004981 cycloalkylmethyl group Chemical group 0.000 abstract 2
- 125000005843 halogen group Chemical group 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 229910052757 nitrogen Inorganic materials 0.000 abstract 2
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- 125000004205 trifluoroethyl group Chemical group [H]C([H])(*)C(F)(F)F 0.000 abstract 2
- 125000000229 (C1-C4)alkoxy group Chemical group 0.000 abstract 1
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 1
- 125000004209 (C1-C8) alkyl group Chemical group 0.000 abstract 1
- 125000006625 (C3-C8) cycloalkyloxy group Chemical group 0.000 abstract 1
- 125000003903 2-propenyl group Chemical group [H]C([*])([H])C([H])=C([H])[H] 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- DHXVGJBLRPWPCS-UHFFFAOYSA-N Tetrahydropyran Chemical group C1CCOCC1 DHXVGJBLRPWPCS-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000004414 alkyl thio group Chemical group 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 125000002393 azetidinyl group Chemical group 0.000 abstract 1
- 125000004069 aziridinyl group Chemical group 0.000 abstract 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000000000 cycloalkoxy group Chemical group 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 125000004184 methoxymethyl group Chemical group [H]C([H])([H])OC([H])([H])* 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 125000002757 morpholinyl group Chemical group 0.000 abstract 1
- 125000005010 perfluoroalkyl group Chemical group 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 125000004193 piperazinyl group Chemical group 0.000 abstract 1
- 125000003386 piperidinyl group Chemical group 0.000 abstract 1
- 125000004621 quinuclidinyl group Chemical group N12C(CC(CC1)CC2)* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
- 125000003718 tetrahydrofuranyl group Chemical group 0.000 abstract 1
- 125000001412 tetrahydropyranyl group Chemical group 0.000 abstract 1
- 125000006173 tetrahydropyranylmethyl group Chemical group 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
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- A—HUMAN NECESSITIES
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/44—Acylated amino or imino radicals
- C07D277/46—Acylated amino or imino radicals by carboxylic acids, or sulfur or nitrogen analogues thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/10—Spiro-condensed systems
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- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/08—Bridged systems
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- Health & Medical Sciences (AREA)
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- Organic Chemistry (AREA)
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- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
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- Virology (AREA)
- Pulmonology (AREA)
- Diabetes (AREA)
- Oncology (AREA)
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- Physical Education & Sports Medicine (AREA)
- Cardiology (AREA)
- Hematology (AREA)
- Rheumatology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Neurosurgery (AREA)
- Dermatology (AREA)
- Heart & Thoracic Surgery (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Obesity (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Hospice & Palliative Care (AREA)
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Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0305213A FR2854158B1 (fr) | 2003-04-25 | 2003-04-25 | Derives de 2-acylamino-4-phenylethiazole, leur preparation et leur application en therapeutique |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR044070A1 true AR044070A1 (es) | 2005-08-24 |
Family
ID=33104460
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP040101382A AR044070A1 (es) | 2003-04-25 | 2004-04-23 | Derivados de 2 -acilamino -4- feniltiazol, su preparacion y su aplicacion en terapeutica |
Country Status (24)
| Country | Link |
|---|---|
| US (2) | US7504511B2 (https=) |
| EP (1) | EP1656373B1 (https=) |
| JP (2) | JP4839208B2 (https=) |
| KR (1) | KR20060006935A (https=) |
| CN (1) | CN1826339A (https=) |
| AR (1) | AR044070A1 (https=) |
| AT (1) | ATE541843T1 (https=) |
| AU (1) | AU2004234101A1 (https=) |
| BR (1) | BRPI0409716A (https=) |
| CA (1) | CA2521158A1 (https=) |
| CO (1) | CO5640106A2 (https=) |
| CR (1) | CR8037A (https=) |
| EC (1) | ECSP056111A (https=) |
| FR (1) | FR2854158B1 (https=) |
| MA (1) | MA27769A1 (https=) |
| MX (1) | MXPA05011522A (https=) |
| NO (1) | NO20054905L (https=) |
| OA (1) | OA13049A (https=) |
| RS (1) | RS20050769A (https=) |
| RU (1) | RU2348630C2 (https=) |
| TN (1) | TNSN05254A1 (https=) |
| TW (1) | TW200510325A (https=) |
| WO (1) | WO2004096798A2 (https=) |
| ZA (1) | ZA200508608B (https=) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JO2527B1 (en) * | 2004-04-06 | 2010-03-17 | شركة جانسين فارماسوتيكا ان. في | Derivatives of second-aza-Spiro- (5,5) -andecan and their use as antihistamines |
| JO2676B1 (en) * | 2004-04-06 | 2012-06-17 | جانسين فارماسوتيكا ان. في | Derivatives of second-aza-spiro- (5,4) -dikan and their use as antihistamines |
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| GB0108876D0 (en) * | 2001-04-09 | 2001-05-30 | Novartis Ag | Organic Compounds |
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| JP2004256429A (ja) * | 2003-02-26 | 2004-09-16 | Sankyo Co Ltd | イソキノリン誘導体 |
| FR2872813B1 (fr) | 2004-07-09 | 2007-01-19 | Sanofi Synthelabo | Derives de 2-carbamide-4-phenylthiazole, leur preparation et leur application en therapeutique |
| FR2876692B1 (fr) * | 2004-10-19 | 2007-02-23 | Sanofi Aventis Sa | Derives de 2-amido-4-phenylthiazole, leur preparation et leur application en therapeutique |
| FR2895989B1 (fr) | 2006-01-06 | 2010-04-30 | Sanofi Aventis | Derives de 2-carbamide-4-phenylthiazole, leur preparation et leur application en therapeutique |
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2003
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2004
- 2004-04-22 CN CNA2004800180511A patent/CN1826339A/zh active Pending
- 2004-04-22 RS YUP-2005/0769A patent/RS20050769A/sr unknown
- 2004-04-22 BR BRPI0409716-5A patent/BRPI0409716A/pt not_active IP Right Cessation
- 2004-04-22 AT AT04742558T patent/ATE541843T1/de active
- 2004-04-22 KR KR1020057020168A patent/KR20060006935A/ko not_active Ceased
- 2004-04-22 CA CA002521158A patent/CA2521158A1/fr not_active Abandoned
- 2004-04-22 RU RU2005136663/04A patent/RU2348630C2/ru not_active IP Right Cessation
- 2004-04-22 WO PCT/FR2004/000981 patent/WO2004096798A2/fr not_active Ceased
- 2004-04-22 EP EP04742558A patent/EP1656373B1/fr not_active Expired - Lifetime
- 2004-04-22 MX MXPA05011522A patent/MXPA05011522A/es unknown
- 2004-04-22 AU AU2004234101A patent/AU2004234101A1/en not_active Abandoned
- 2004-04-22 ZA ZA200508608A patent/ZA200508608B/en unknown
- 2004-04-22 OA OA1200500305A patent/OA13049A/fr unknown
- 2004-04-22 JP JP2006505808A patent/JP4839208B2/ja not_active Expired - Fee Related
- 2004-04-23 AR ARP040101382A patent/AR044070A1/es unknown
- 2004-04-26 TW TW093111632A patent/TW200510325A/zh unknown
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- 2005-10-11 CR CR8037A patent/CR8037A/es not_active Application Discontinuation
- 2005-10-19 US US11/253,998 patent/US7504511B2/en not_active Expired - Fee Related
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Also Published As
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|---|---|
| CN1826339A (zh) | 2006-08-30 |
| TNSN05254A1 (en) | 2007-07-10 |
| WO2004096798A2 (fr) | 2004-11-11 |
| OA13049A (fr) | 2006-11-10 |
| CR8037A (es) | 2008-07-29 |
| ECSP056111A (es) | 2006-03-01 |
| TW200510325A (en) | 2005-03-16 |
| CA2521158A1 (fr) | 2004-11-11 |
| US20060135575A1 (en) | 2006-06-22 |
| NO20054905D0 (no) | 2005-10-24 |
| EP1656373A2 (fr) | 2006-05-17 |
| US7504511B2 (en) | 2009-03-17 |
| ZA200508608B (en) | 2007-01-31 |
| MXPA05011522A (es) | 2006-01-23 |
| US20090156574A1 (en) | 2009-06-18 |
| RS20050769A (sr) | 2007-11-15 |
| JP2006524669A (ja) | 2006-11-02 |
| AU2004234101A1 (en) | 2004-11-11 |
| RU2005136663A (ru) | 2006-03-20 |
| WO2004096798A3 (fr) | 2006-01-26 |
| FR2854158A1 (fr) | 2004-10-29 |
| RU2348630C2 (ru) | 2009-03-10 |
| US7777041B2 (en) | 2010-08-17 |
| MA27769A1 (fr) | 2006-02-01 |
| FR2854158B1 (fr) | 2006-11-17 |
| NO20054905L (no) | 2006-01-25 |
| ATE541843T1 (de) | 2012-02-15 |
| JP4839208B2 (ja) | 2011-12-21 |
| BRPI0409716A (pt) | 2006-05-02 |
| JP2011126891A (ja) | 2011-06-30 |
| KR20060006935A (ko) | 2006-01-20 |
| EP1656373B1 (fr) | 2012-01-18 |
| CO5640106A2 (es) | 2006-05-31 |
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