AR033861A1 - Sistema terapeutico transcutaneo con testosterona y procedimiento para su fabricacion - Google Patents
Sistema terapeutico transcutaneo con testosterona y procedimiento para su fabricacionInfo
- Publication number
- AR033861A1 AR033861A1 ARP020100513A ARP020100513A AR033861A1 AR 033861 A1 AR033861 A1 AR 033861A1 AR P020100513 A ARP020100513 A AR P020100513A AR P020100513 A ARP020100513 A AR P020100513A AR 033861 A1 AR033861 A1 AR 033861A1
- Authority
- AR
- Argentina
- Prior art keywords
- penetration
- therapeutic system
- testosterone
- substance
- transcutaneous therapeutic
- Prior art date
Links
- MUMGGOZAMZWBJJ-DYKIIFRCSA-N Testostosterone Chemical compound O=C1CC[C@]2(C)[C@H]3CC[C@](C)([C@H](CC4)O)[C@@H]4[C@@H]3CCC2=C1 MUMGGOZAMZWBJJ-DYKIIFRCSA-N 0.000 title abstract 4
- 229960003604 testosterone Drugs 0.000 title abstract 2
- 230000001225 therapeutic effect Effects 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 239000003163 gonadal steroid hormone Substances 0.000 abstract 3
- 239000000126 substance Substances 0.000 abstract 3
- 150000002148 esters Chemical class 0.000 abstract 2
- 239000011159 matrix material Substances 0.000 abstract 2
- 230000035515 penetration Effects 0.000 abstract 2
- 239000013543 active substance Substances 0.000 abstract 1
- 239000002998 adhesive polymer Substances 0.000 abstract 1
- 235000014113 dietary fatty acids Nutrition 0.000 abstract 1
- 229930195729 fatty acid Natural products 0.000 abstract 1
- 239000000194 fatty acid Substances 0.000 abstract 1
- 150000004665 fatty acids Chemical class 0.000 abstract 1
- 150000002191 fatty alcohols Chemical class 0.000 abstract 1
- 239000010410 layer Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 229920000642 polymer Polymers 0.000 abstract 1
- 230000001737 promoting effect Effects 0.000 abstract 1
- 239000011241 protective layer Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
- A61K9/7061—Polyacrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/26—Androgens
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dermatology (AREA)
- Endocrinology (AREA)
- Virology (AREA)
- Reproductive Health (AREA)
- Oncology (AREA)
- Diabetes (AREA)
- Communicable Diseases (AREA)
- Gynecology & Obstetrics (AREA)
- Pregnancy & Childbirth (AREA)
- Molecular Biology (AREA)
- Tropical Medicine & Parasitology (AREA)
- AIDS & HIV (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
Un sistema terapéutico transcutáneo para la administración de hormonas sexuales, que tiene una capa posterior impermeable a la sustancia activa, y unida a ella una matriz de polímeros adhesiva que contiene una hormona sexual junto con sustancias favorecedoras de la penetración, y una capa protectora desprendible antes de la aplicación, se caracteriza porque la matriz de polímeros contiene la hormona sexual testosterona junto con una mezcla de al menos una sustancia que estimula la penetración, perteneciente al grupo que comprende ésteres de alcoholes grasos y ésteres de ácidos grasos, y al menos una sustancia de fácil volatilidad y favorecedora de la penetración.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10107663A DE10107663B4 (de) | 2001-02-19 | 2001-02-19 | Testosteronhaltiges transdermales therapeutisches System, Verfahren zu seiner Herstellung und seine Verwendung |
Publications (1)
Publication Number | Publication Date |
---|---|
AR033861A1 true AR033861A1 (es) | 2004-01-07 |
Family
ID=7674535
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP020100513A AR033861A1 (es) | 2001-02-19 | 2002-02-15 | Sistema terapeutico transcutaneo con testosterona y procedimiento para su fabricacion |
Country Status (12)
Country | Link |
---|---|
US (1) | US20040120994A1 (es) |
EP (1) | EP1361869B1 (es) |
JP (1) | JP4851683B2 (es) |
KR (1) | KR100787545B1 (es) |
CN (1) | CN100349571C (es) |
AR (1) | AR033861A1 (es) |
AT (1) | ATE522205T1 (es) |
AU (1) | AU2002247690B2 (es) |
CA (1) | CA2438657C (es) |
DE (1) | DE10107663B4 (es) |
ES (1) | ES2368830T3 (es) |
WO (1) | WO2002066018A2 (es) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7033998B2 (en) * | 2003-04-11 | 2006-04-25 | All Natural Fmg, Inc. | Alcohol-free transdermal insulin composition and processes for manufacture and use thereof |
JO2492B1 (en) | 2003-04-28 | 2009-10-05 | شيرينج ايه جي | A pharmaceutical formula in the form of aqueous gel for the skin use of its active ingredients |
US7850987B2 (en) * | 2004-04-08 | 2010-12-14 | Micronutrient, Llc | Nutrient composition(s) and system(s) for individualized, responsive dosing regimens |
DE102006026060B4 (de) * | 2006-01-12 | 2013-01-31 | Lts Lohmann Therapie-Systeme Ag | Transdermales Therapeutisches System enthaltend als Wirkstoff Nikotin und Verfahren zur Herstellung solcher Systeme |
KR100871531B1 (ko) * | 2007-01-16 | 2008-12-05 | 익수제약 주식회사 | 테스토스테론 외용제 |
JP5338030B2 (ja) * | 2007-01-31 | 2013-11-13 | 大正製薬株式会社 | アダパレン含有外用剤組成物 |
US11304960B2 (en) | 2009-01-08 | 2022-04-19 | Chandrashekar Giliyar | Steroidal compositions |
AU2011224350B2 (en) * | 2010-03-09 | 2015-07-02 | Alkermes Pharma Ireland Limited | Alcohol resistant enteric pharmaceutical compositions |
JO3755B1 (ar) * | 2011-01-26 | 2021-01-31 | Ferring Bv | تركيبات تستوستيرون |
AU2014330779A1 (en) * | 2013-10-01 | 2016-04-07 | Novartis Ag | Combination |
SI3265140T1 (sl) * | 2015-03-02 | 2021-11-30 | Medlab Clinical U.S., Inc. | Dostavni sistemi za dostavo skozi sluznico ali skozi kožo |
EP3650857B1 (en) * | 2017-07-07 | 2021-10-06 | Panasonic Intellectual Property Management Co., Ltd. | Information provision method, information processing system, use of an information terminal, and information processing method |
JP7170250B2 (ja) * | 2017-07-07 | 2022-11-14 | パナソニックIpマネジメント株式会社 | 情報提供方法、情報処理システム、及び情報処理方法 |
EP3650855A4 (en) * | 2017-07-07 | 2020-07-01 | Panasonic Intellectual Property Management Co., Ltd. | INFORMATION PROVIDING PROCESS, INFORMATION PROCESSING SYSTEM, INFORMATION TERMINAL AND INFORMATION PROCESSING PROCESS |
EP3705123A4 (en) * | 2017-10-30 | 2021-08-04 | Teikoku Seiyaku Co., Ltd. | TRANSDERMALLY ADMINISTRATIVE PREPARATION |
Family Cites Families (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4915950A (en) * | 1988-02-12 | 1990-04-10 | Cygnus Research Corporation | Printed transdermal drug delivery device |
DE58909570D1 (de) * | 1988-10-27 | 1996-02-22 | Schering Ag | Mittel zur transdermalen applikation enthaltend gestoden |
DE3836862A1 (de) * | 1988-10-27 | 1990-05-03 | Schering Ag | Mittel zur transdermalen applikation von steroidhormonen |
US5164190A (en) * | 1990-12-11 | 1992-11-17 | Theratech, Inc. | Subsaturated transdermal drug delivery device exhibiting enhanced drug flux |
US5152997A (en) * | 1990-12-11 | 1992-10-06 | Theratech, Inc. | Method and device for transdermally administering testosterone across nonscrotal skin at therapeutically effective levels |
JPH04261119A (ja) * | 1991-02-13 | 1992-09-17 | Lintec Corp | 経皮吸収型貼付剤 |
DE4210165A1 (de) * | 1991-07-30 | 1993-02-04 | Schering Ag | Transdermale therapeutische systeme |
CA2101496A1 (en) * | 1992-07-31 | 1994-02-01 | Masao Kobayashi | Base for transdermal administration |
US5635466A (en) * | 1992-08-21 | 1997-06-03 | The Procter & Gamble Company | Concentrated liquid detergent composition comprising an alkyl ether sulphate and a process for making the composition |
DE4310012A1 (de) * | 1993-03-27 | 1994-09-29 | Roehm Gmbh | Dermales therapeutisches System aus einer schmelzfähigen Poly(meth)acrylat-Mischung |
JP3576608B2 (ja) * | 1994-11-15 | 2004-10-13 | 日東電工株式会社 | 貼付剤および貼付製剤 |
FR2732223B1 (fr) * | 1995-03-30 | 1997-06-13 | Sanofi Sa | Composition pharmaceutique pour administration transdermique |
DE19701949A1 (de) * | 1997-01-13 | 1998-07-16 | Jenapharm Gmbh | Transdermales therapeutisches System |
KR100215027B1 (ko) * | 1997-01-27 | 1999-08-16 | 성재갑 | 스테로이드계 약물의 경피흡수투여용 조성물 및 이를 포함하는 경피흡수투여용 제형 |
WO1999032153A1 (en) * | 1997-12-22 | 1999-07-01 | Alza Corporation | Monoglyceride and ethyl palmitate permeation enhancer compositions |
GB9800526D0 (en) * | 1998-01-12 | 1998-03-11 | Ciba Geigy Ag | Organic compounds |
DE19918106A1 (de) * | 1999-04-22 | 2000-10-26 | Lohmann Therapie Syst Lts | Transdermales therapeutisches System mit neutralisierten Acrylathaftklebern |
DE10019171A1 (de) * | 2000-04-07 | 2001-10-18 | Schering Ag | Zusammensetzungen zur Verwendung als Penetrationsverstärker in transdermalen Formulierungen für hoch lipophile Wirkstoffe |
KR100403051B1 (ko) * | 2000-07-25 | 2003-10-23 | 일양약품주식회사 | 음낭 외 피부에 적용가능한 남성호르몬 경피흡수 패취제 |
-
2001
- 2001-02-19 DE DE10107663A patent/DE10107663B4/de not_active Expired - Lifetime
-
2002
- 2002-02-07 US US10/468,436 patent/US20040120994A1/en not_active Abandoned
- 2002-02-07 AU AU2002247690A patent/AU2002247690B2/en not_active Ceased
- 2002-02-07 ES ES02716736T patent/ES2368830T3/es not_active Expired - Lifetime
- 2002-02-07 KR KR1020037010810A patent/KR100787545B1/ko active IP Right Grant
- 2002-02-07 WO PCT/EP2002/001258 patent/WO2002066018A2/de active Application Filing
- 2002-02-07 CA CA2438657A patent/CA2438657C/en not_active Expired - Lifetime
- 2002-02-07 JP JP2002565578A patent/JP4851683B2/ja not_active Expired - Fee Related
- 2002-02-07 AT AT02716736T patent/ATE522205T1/de active
- 2002-02-07 CN CNB028051742A patent/CN100349571C/zh not_active Expired - Fee Related
- 2002-02-07 EP EP02716736A patent/EP1361869B1/de not_active Expired - Lifetime
- 2002-02-15 AR ARP020100513A patent/AR033861A1/es not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
EP1361869B1 (de) | 2011-08-31 |
JP2004517965A (ja) | 2004-06-17 |
CA2438657C (en) | 2010-10-12 |
US20040120994A1 (en) | 2004-06-24 |
JP4851683B2 (ja) | 2012-01-11 |
EP1361869A2 (de) | 2003-11-19 |
AU2002247690B2 (en) | 2006-06-22 |
DE10107663B4 (de) | 2004-09-09 |
ATE522205T1 (de) | 2011-09-15 |
CN1717239A (zh) | 2006-01-04 |
WO2002066018A3 (de) | 2003-04-24 |
CN100349571C (zh) | 2007-11-21 |
KR20030072630A (ko) | 2003-09-15 |
CA2438657A1 (en) | 2002-08-29 |
ES2368830T3 (es) | 2011-11-22 |
DE10107663A1 (de) | 2002-09-05 |
WO2002066018A2 (de) | 2002-08-29 |
KR100787545B1 (ko) | 2007-12-21 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA | Abandonment or withdrawal |