AR033861A1 - Sistema terapeutico transcutaneo con testosterona y procedimiento para su fabricacion - Google Patents

Sistema terapeutico transcutaneo con testosterona y procedimiento para su fabricacion

Info

Publication number
AR033861A1
AR033861A1 ARP020100513A ARP020100513A AR033861A1 AR 033861 A1 AR033861 A1 AR 033861A1 AR P020100513 A ARP020100513 A AR P020100513A AR P020100513 A ARP020100513 A AR P020100513A AR 033861 A1 AR033861 A1 AR 033861A1
Authority
AR
Argentina
Prior art keywords
penetration
therapeutic system
testosterone
substance
transcutaneous therapeutic
Prior art date
Application number
ARP020100513A
Other languages
English (en)
Inventor
Frank Theobald
Original Assignee
Lohmann Therapie Syst Lts
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lohmann Therapie Syst Lts filed Critical Lohmann Therapie Syst Lts
Publication of AR033861A1 publication Critical patent/AR033861A1/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061Polyacrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/26Androgens

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Endocrinology (AREA)
  • Virology (AREA)
  • Reproductive Health (AREA)
  • Oncology (AREA)
  • Diabetes (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • AIDS & HIV (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Un sistema terapéutico transcutáneo para la administración de hormonas sexuales, que tiene una capa posterior impermeable a la sustancia activa, y unida a ella una matriz de polímeros adhesiva que contiene una hormona sexual junto con sustancias favorecedoras de la penetración, y una capa protectora desprendible antes de la aplicación, se caracteriza porque la matriz de polímeros contiene la hormona sexual testosterona junto con una mezcla de al menos una sustancia que estimula la penetración, perteneciente al grupo que comprende ésteres de alcoholes grasos y ésteres de ácidos grasos, y al menos una sustancia de fácil volatilidad y favorecedora de la penetración.
ARP020100513A 2001-02-19 2002-02-15 Sistema terapeutico transcutaneo con testosterona y procedimiento para su fabricacion AR033861A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10107663A DE10107663B4 (de) 2001-02-19 2001-02-19 Testosteronhaltiges transdermales therapeutisches System, Verfahren zu seiner Herstellung und seine Verwendung

Publications (1)

Publication Number Publication Date
AR033861A1 true AR033861A1 (es) 2004-01-07

Family

ID=7674535

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP020100513A AR033861A1 (es) 2001-02-19 2002-02-15 Sistema terapeutico transcutaneo con testosterona y procedimiento para su fabricacion

Country Status (12)

Country Link
US (1) US20040120994A1 (es)
EP (1) EP1361869B1 (es)
JP (1) JP4851683B2 (es)
KR (1) KR100787545B1 (es)
CN (1) CN100349571C (es)
AR (1) AR033861A1 (es)
AT (1) ATE522205T1 (es)
AU (1) AU2002247690B2 (es)
CA (1) CA2438657C (es)
DE (1) DE10107663B4 (es)
ES (1) ES2368830T3 (es)
WO (1) WO2002066018A2 (es)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7033998B2 (en) * 2003-04-11 2006-04-25 All Natural Fmg, Inc. Alcohol-free transdermal insulin composition and processes for manufacture and use thereof
JO2492B1 (en) 2003-04-28 2009-10-05 شيرينج ايه جي A pharmaceutical formula in the form of aqueous gel for the skin use of its active ingredients
US7850987B2 (en) * 2004-04-08 2010-12-14 Micronutrient, Llc Nutrient composition(s) and system(s) for individualized, responsive dosing regimens
DE102006026060B4 (de) * 2006-01-12 2013-01-31 Lts Lohmann Therapie-Systeme Ag Transdermales Therapeutisches System enthaltend als Wirkstoff Nikotin und Verfahren zur Herstellung solcher Systeme
KR100871531B1 (ko) * 2007-01-16 2008-12-05 익수제약 주식회사 테스토스테론 외용제
JP5338030B2 (ja) * 2007-01-31 2013-11-13 大正製薬株式会社 アダパレン含有外用剤組成物
US11304960B2 (en) 2009-01-08 2022-04-19 Chandrashekar Giliyar Steroidal compositions
JP5819329B2 (ja) * 2010-03-09 2015-11-24 アルカーメス ファーマ アイルランド リミテッド アルコール耐性腸溶性医薬組成物
JO3755B1 (ar) * 2011-01-26 2021-01-31 Ferring Bv تركيبات تستوستيرون
AU2014330779A1 (en) * 2013-10-01 2016-04-07 Novartis Ag Combination
DK3928763T3 (da) * 2015-03-02 2022-05-23 Medlab Clinical U S Inc Transmukosale og transdermale leveringssystemer
WO2019008994A1 (ja) * 2017-07-07 2019-01-10 パナソニックIpマネジメント株式会社 情報提供方法、情報処理システム、情報端末、及び情報処理方法
WO2019008988A1 (ja) * 2017-07-07 2019-01-10 パナソニックIpマネジメント株式会社 情報提供方法、情報処理システム、情報端末、及び情報処理方法
JP7170250B2 (ja) * 2017-07-07 2022-11-14 パナソニックIpマネジメント株式会社 情報提供方法、情報処理システム、及び情報処理方法
US20200330371A1 (en) * 2017-10-30 2020-10-22 Teikoku Seiyaku Co., Ltd. Transdermally administrable preparation

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4915950A (en) * 1988-02-12 1990-04-10 Cygnus Research Corporation Printed transdermal drug delivery device
ATE132751T1 (de) * 1988-10-27 1996-01-15 Schering Ag Mittel zur transdermalen applikation enthaltend gestoden
DE3836862A1 (de) * 1988-10-27 1990-05-03 Schering Ag Mittel zur transdermalen applikation von steroidhormonen
US5164190A (en) * 1990-12-11 1992-11-17 Theratech, Inc. Subsaturated transdermal drug delivery device exhibiting enhanced drug flux
US5152997A (en) * 1990-12-11 1992-10-06 Theratech, Inc. Method and device for transdermally administering testosterone across nonscrotal skin at therapeutically effective levels
JPH04261119A (ja) * 1991-02-13 1992-09-17 Lintec Corp 経皮吸収型貼付剤
DE4210165A1 (de) * 1991-07-30 1993-02-04 Schering Ag Transdermale therapeutische systeme
CA2101496A1 (en) * 1992-07-31 1994-02-01 Masao Kobayashi Base for transdermal administration
US5635466A (en) * 1992-08-21 1997-06-03 The Procter & Gamble Company Concentrated liquid detergent composition comprising an alkyl ether sulphate and a process for making the composition
DE4310012A1 (de) * 1993-03-27 1994-09-29 Roehm Gmbh Dermales therapeutisches System aus einer schmelzfähigen Poly(meth)acrylat-Mischung
JP3576608B2 (ja) * 1994-11-15 2004-10-13 日東電工株式会社 貼付剤および貼付製剤
FR2732223B1 (fr) * 1995-03-30 1997-06-13 Sanofi Sa Composition pharmaceutique pour administration transdermique
DE19701949A1 (de) * 1997-01-13 1998-07-16 Jenapharm Gmbh Transdermales therapeutisches System
KR100215027B1 (ko) * 1997-01-27 1999-08-16 성재갑 스테로이드계 약물의 경피흡수투여용 조성물 및 이를 포함하는 경피흡수투여용 제형
AU1728099A (en) * 1997-12-22 1999-07-12 Alza Corporation Monoglyceride and ethyl palmitate permeation enhancer compositions
GB9800526D0 (en) * 1998-01-12 1998-03-11 Ciba Geigy Ag Organic compounds
DE19918106A1 (de) * 1999-04-22 2000-10-26 Lohmann Therapie Syst Lts Transdermales therapeutisches System mit neutralisierten Acrylathaftklebern
DE10019171A1 (de) * 2000-04-07 2001-10-18 Schering Ag Zusammensetzungen zur Verwendung als Penetrationsverstärker in transdermalen Formulierungen für hoch lipophile Wirkstoffe
KR100403051B1 (ko) * 2000-07-25 2003-10-23 일양약품주식회사 음낭 외 피부에 적용가능한 남성호르몬 경피흡수 패취제

Also Published As

Publication number Publication date
ES2368830T3 (es) 2011-11-22
AU2002247690B2 (en) 2006-06-22
KR20030072630A (ko) 2003-09-15
US20040120994A1 (en) 2004-06-24
CN1717239A (zh) 2006-01-04
DE10107663A1 (de) 2002-09-05
CA2438657A1 (en) 2002-08-29
CN100349571C (zh) 2007-11-21
EP1361869A2 (de) 2003-11-19
EP1361869B1 (de) 2011-08-31
DE10107663B4 (de) 2004-09-09
WO2002066018A3 (de) 2003-04-24
CA2438657C (en) 2010-10-12
JP2004517965A (ja) 2004-06-17
KR100787545B1 (ko) 2007-12-21
JP4851683B2 (ja) 2012-01-11
ATE522205T1 (de) 2011-09-15
WO2002066018A2 (de) 2002-08-29

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Legal Events

Date Code Title Description
FA Abandonment or withdrawal