AR017199A1 - Sal de monofosfato de isopropil-metil-[2-(3-n-propoxifenoxi)etil]-amina, proceso para su preparacion, formulacion farmaceutica que los contiene y su uso enel tratamiento del dolor. - Google Patents

Sal de monofosfato de isopropil-metil-[2-(3-n-propoxifenoxi)etil]-amina, proceso para su preparacion, formulacion farmaceutica que los contiene y su uso enel tratamiento del dolor.

Info

Publication number
AR017199A1
AR017199A1 ARP980106241A ARP980106241A AR017199A1 AR 017199 A1 AR017199 A1 AR 017199A1 AR P980106241 A ARP980106241 A AR P980106241A AR P980106241 A ARP980106241 A AR P980106241A AR 017199 A1 AR017199 A1 AR 017199A1
Authority
AR
Argentina
Prior art keywords
ethyl
amine
methyl
propoxyphenoxy
preparation
Prior art date
Application number
ARP980106241A
Other languages
English (en)
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of AR017199A1 publication Critical patent/AR017199A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C217/06—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted
    • C07C217/14—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring
    • C07C217/18—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted
    • C07C217/20—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted by halogen atoms, by trihalomethyl, nitro or nitroso groups, or by singly-bound oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A61P23/02—Local anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Anesthesiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Sal de monofosfato de isopropil-metil-[2-(3-n-propoxifenoxi)etil]amina; proceso para la preparacion de dicha sal de monofosfato de isopropil-metil-[2-(3-n-propoxifenoxi)etil]amina; formulacion farmacéutica que la contiene y su uso en medicina. Laiso propil-metil-[2-(3-n-propoxifenoxi)etil]amina es uncompuesto con propiedades anestésicas; util comocompuesto anestésico para el tratamiento del dolor, incluso del dolor localizado. La sal cristalina demonofosfato deisopropil-metil-[2-(3-n-propoxifen oxi)etil]amina se puede utilizar para introducir un intermediario cristalino en el proceso para la preparacionde isopropil-metil-[2-(3-n-propoxifenoxi)etil]amina. Esto agrega un sencillo y conveniente paso depurificacion en una secuencia de reaccion es en la que todoslos demás intermediarios son jarabes. De esa manera, se evita la destilacion de los procesos de la técnica anterior que tanto tiempo y energía consume. Lacristalizacion de la sal demonofosfato de isopropil-metil[2-(3-n-propoxifen oxi)etil]amina a origen a un intermediario de alta pureza que puede convertirse asu vez a la correspondiente isopropil-metil-[2-(3-n-propoxifenoxi)etil]amina mediante un sencillo paso dealcalinizacion.
ARP980106241A 1997-12-22 1998-12-09 Sal de monofosfato de isopropil-metil-[2-(3-n-propoxifenoxi)etil]-amina, proceso para su preparacion, formulacion farmaceutica que los contiene y su uso enel tratamiento del dolor. AR017199A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9704835A SE9704835D0 (sv) 1997-12-22 1997-12-22 New compound

Publications (1)

Publication Number Publication Date
AR017199A1 true AR017199A1 (es) 2001-08-22

Family

ID=20409538

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP980106241A AR017199A1 (es) 1997-12-22 1998-12-09 Sal de monofosfato de isopropil-metil-[2-(3-n-propoxifenoxi)etil]-amina, proceso para su preparacion, formulacion farmaceutica que los contiene y su uso enel tratamiento del dolor.

Country Status (22)

Country Link
US (1) US6235792B1 (es)
EP (1) EP1047663A1 (es)
JP (1) JP2001526254A (es)
KR (1) KR20010033407A (es)
CN (1) CN1280559A (es)
AR (1) AR017199A1 (es)
AU (1) AU1989299A (es)
BR (1) BR9814381A (es)
CA (1) CA2314989A1 (es)
EE (1) EE200000384A (es)
HU (1) HUP0004428A3 (es)
ID (1) ID26940A (es)
IL (1) IL136829A0 (es)
IS (1) IS5544A (es)
NO (1) NO20003216L (es)
PL (1) PL341525A1 (es)
SE (1) SE9704835D0 (es)
SK (1) SK8062000A3 (es)
TR (1) TR200002012T2 (es)
TW (1) TW455590B (es)
WO (1) WO1999032431A1 (es)
ZA (1) ZA9811237B (es)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH380746A (de) * 1958-11-06 1964-08-15 Ciba Geigy Verfahren zur Herstellung neuer sekundärer Amine
AR004691A1 (es) * 1995-10-27 1999-03-10 Astrazeneca Ab Nuevos derivados de [3-alcoxi-fenoxi-)-etil]-dialquilamina, una composicion farmaceutica que los comprende, su uso como anestesicos locales y unprocedimiento para su preparacion

Also Published As

Publication number Publication date
SK8062000A3 (en) 2001-02-12
KR20010033407A (ko) 2001-04-25
NO20003216D0 (no) 2000-06-21
ID26940A (id) 2001-02-22
SE9704835D0 (sv) 1997-12-22
NO20003216L (no) 2000-06-21
IL136829A0 (en) 2001-06-14
US6235792B1 (en) 2001-05-22
WO1999032431A1 (en) 1999-07-01
TW455590B (en) 2001-09-21
CN1280559A (zh) 2001-01-17
AU1989299A (en) 1999-07-12
BR9814381A (pt) 2000-10-10
EP1047663A1 (en) 2000-11-02
HUP0004428A2 (hu) 2002-03-28
PL341525A1 (en) 2001-04-23
TR200002012T2 (tr) 2000-10-23
CA2314989A1 (en) 1999-07-01
ZA9811237B (en) 1999-07-19
EE200000384A (et) 2001-12-17
JP2001526254A (ja) 2001-12-18
HUP0004428A3 (en) 2002-04-29
IS5544A (is) 2000-06-21

Similar Documents

Publication Publication Date Title
BR9910921A (pt) Composto, processo para preparar o mesmo, formulação farmacêutica, uso de um composto, e, processo para a profilaxia e/ou tratamento de condições clìnicas associadas com a resistência à insulina
ES2189782T3 (es) Derivados de pteridina opticamente activos.
ES2082755T3 (es) Derivados de acido 3-desmetil-mevalonico, procedimiento para su preparacion, preparados farmaceuticos a base de estos compuestos, su utilizacion asi como productos intermedios.
IT1256345B (it) Esteri nitrici di derivati dell'acido 2-(2,6-di-alo-fenilammino) fenilacetico e procedimento per la loro preparazione
DK164937C (da) Analogifremgangsmaade til fremstilling af 1-alkyl-2-aminotetralinderivater eller farmaceutisk acceptable syreadditionssalte deraf samt 1-alkyl-2-aminotetralinderivater til anvendelse som udgangsmateriale i fremgangsmaaden
BR9910928A (pt) Composto, processo para a prepará-lo, uso do mesmo, formulação, e, processo para a profilaxia e/ou tratamento de condições clinicas associadas com resistência a insulina
ES2038623T3 (es) Procedimiento para preparar soluciones de oxazafosforinas con estabilidad mejorada.
MY101132A (en) An optically pure pipecoloxylidide hydrochloride and a process for its preparation
MX9205577A (es) Derivados de carbamato de 4-amino-3-isoxazolidinonas, 3-amino-1-hidroxipirrolidin-2-onas y analogos del acido 1-amino-1-ciclopropanocarboxilico, un procedimiento para su preparacion y su uso como medicamentos.
AR017199A1 (es) Sal de monofosfato de isopropil-metil-[2-(3-n-propoxifenoxi)etil]-amina, proceso para su preparacion, formulacion farmaceutica que los contiene y su uso enel tratamiento del dolor.
ES8101590A1 (es) Un procedimiento para la preparacion de pirimido-2-benzace- pinas
ATE41146T1 (de) Irreversible dopamin-b-hydroxylase-inhibitoren.
CA2029704A1 (en) Pyrimidone derivatives and analogs in the treatment of asthma or certain skin disorders
DK0681473T3 (da) Præparater, der indeholder tandospiron eller dets analoger
ES8501748A1 (es) Un procedimiento para preparar derivados de benzamida
IT1188178B (it) Sali della citidin-difospocolina particolarmente idonei per uso orale
NO850580L (no) Isoksazol-derivater, fremgangsmaate til deres fremstilling, legemidler inneholdende disse forbindelser
PT84680B (pt) Processo para a preparacao de derivados de 1,5-benzotiazepina e de composicoes farmaceuticas que os contem
AR008371A1 (es) Una sal de adicion con acido de una 10-aminoalifatil-dibenz[b,f],oxepina, su empleo; procedimiento para su elaboracion, una 10-aminoalifatil-dibenz[b,f]oxepina, una preparacion farmaceutica que contiene dicha sal o dicha oxepina y un procedimiento para el tratamiento de enfermedades neurodegenerativ
FI864970A (fi) Nya kristallina salter av aryloxi-propanolaminer, foerfarande foer deras framstaellning och deras anvaendning.
FI890779A (fi) 14,17 -etano-14 -estratrieenejä, menetelmä niiden valmistamiseksi ja niitä sisältäviä, ehkäisyaineina käytettäviä valmisteita
BR9814496A (pt) Composto, processos para a preparação de cristais de sementes da modificação termodinamicamente estável i de ramatroban, para a preparação de uma forma termodinamicamente estável de ramatroban, medicamento, e, uso de uma modificação termodinamicamente estável de ramatroban
DK364386D0 (da) 1-alkyl-ergolinyl-thiourinstofderivater og fremgangsmaade til fremstilling deraf samt deres anvendelse
ES2054887T3 (es) Nuevos 5-halogeno-tienoisotiazol-3(2h)-on-1,1-dioxidos basicamente substituidos, un procedimiento para su obtencion y los preparados farmaceuticos que contienen estos compuestos.
HU9603590D0 (en) New salts of 2-[(2,6-dichloro-phenyl)-amino]-phenyl-acetoxy-acetic acid with organic bases, pharmaceutical compns. contg. them and process for preparing the said compds.

Legal Events

Date Code Title Description
FA Abandonment or withdrawal