IT1188178B - Sali della citidin-difospocolina particolarmente idonei per uso orale - Google Patents
Sali della citidin-difospocolina particolarmente idonei per uso oraleInfo
- Publication number
- IT1188178B IT1188178B IT21447/85A IT2144785A IT1188178B IT 1188178 B IT1188178 B IT 1188178B IT 21447/85 A IT21447/85 A IT 21447/85A IT 2144785 A IT2144785 A IT 2144785A IT 1188178 B IT1188178 B IT 1188178B
- Authority
- IT
- Italy
- Prior art keywords
- salts
- diphospocoline
- citidin
- particularly suitable
- oral use
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
- C07H19/10—Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Neurology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Neurosurgery (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Hospice & Palliative Care (AREA)
- Cardiology (AREA)
- Psychiatry (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Cosmetics (AREA)
Priority Applications (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT21447/85A IT1188178B (it) | 1985-07-05 | 1985-07-05 | Sali della citidin-difospocolina particolarmente idonei per uso orale |
AT86108677T ATE62250T1 (de) | 1985-07-05 | 1986-06-25 | Cytidine-diphosphocholine salze, besonders geeignet fuer oralen gebrauch. |
DE8686108677T DE3678498D1 (de) | 1985-07-05 | 1986-06-25 | Cytidine-diphosphocholine salze, besonders geeignet fuer oralen gebrauch. |
EP86108677A EP0207436B1 (en) | 1985-07-05 | 1986-06-25 | New cytidine-diphosphocholine salts, particularly suitable for oral use |
US06/878,697 US4789666A (en) | 1985-07-05 | 1986-06-26 | Cytidine-diphosphocholine salts, particularly suitable for oral use |
JP61156325A JPS6212794A (ja) | 1985-07-05 | 1986-07-04 | 特に経口使用に適する新シチジンジホスホコリン塩、その製造方法及びそれからなる治療薬 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT21447/85A IT1188178B (it) | 1985-07-05 | 1985-07-05 | Sali della citidin-difospocolina particolarmente idonei per uso orale |
Publications (2)
Publication Number | Publication Date |
---|---|
IT8521447A0 IT8521447A0 (it) | 1985-07-05 |
IT1188178B true IT1188178B (it) | 1988-01-07 |
Family
ID=11181915
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT21447/85A IT1188178B (it) | 1985-07-05 | 1985-07-05 | Sali della citidin-difospocolina particolarmente idonei per uso orale |
Country Status (6)
Country | Link |
---|---|
US (1) | US4789666A (it) |
EP (1) | EP0207436B1 (it) |
JP (1) | JPS6212794A (it) |
AT (1) | ATE62250T1 (it) |
DE (1) | DE3678498D1 (it) |
IT (1) | IT1188178B (it) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1990004400A1 (en) * | 1988-10-27 | 1990-05-03 | Massachusetts Institute Of Technology | PROCESS FOR INCREASING PHOSPHATIDYLCHOLINE $i(IN VIVO) |
KR0177841B1 (ko) * | 1992-01-30 | 1999-04-01 | 나까무라 간노스께 | 시티딘 디인산 콜린의 제조방법 |
EP0566135A1 (en) * | 1992-04-17 | 1993-10-20 | Takeda Chemical Industries, Ltd. | Transmucosal composition comprising a peptide and a cytidine derivative |
WO1999033476A1 (en) * | 1997-12-24 | 1999-07-08 | Interneuron Pharmaceuticals, Inc. | Hyperhydrated citicoline, process and use |
US7915233B1 (en) | 1998-08-31 | 2011-03-29 | Wellstat Therapeutics Corporation | Compositions and methods for treatment of mitochondrial diseases |
US6472378B2 (en) * | 1998-08-31 | 2002-10-29 | Pro-Neuron, Inc. | Compositions and methods for treatment of mitochondrial diseases |
US7807654B2 (en) * | 1998-08-31 | 2010-10-05 | Wellstat Therapeutics Corporation | Compositions and methods for treatment of mitochondrial diseases |
HU225988B1 (en) * | 2001-09-05 | 2008-02-28 | Yamasa Corp | Use of cytidine-phosphocholine for producing pharmaceutical compositions for diabetic neuropathy |
JPWO2004006940A1 (ja) * | 2002-07-11 | 2005-11-10 | ヤマサ醤油株式会社 | 薬剤誘発性神経障害用医薬組成物 |
WO2005112635A2 (en) * | 2004-05-13 | 2005-12-01 | Massachusetts Institute Of Technology | Uridine effects on dopamine release |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1189549A (en) * | 1967-12-18 | 1970-04-29 | Takeda Chemical Industries Ltd | A Method for Production of Cytidine (Deoxycytidine)-5'-Diphosphate Choline and Intermediates therefor |
NL149812B (nl) * | 1969-04-24 | 1976-06-15 | Takeda Chemical Industries Ltd | Werkwijze ter bereiding van farmaceutische preparaten, alsmede werkwijze ter bereiding van kristallijn cytidine-5'-difosfaat-choline-monohydraat. |
JPS5517769B2 (it) * | 1972-01-10 | 1980-05-14 | ||
JPS6043078B2 (ja) * | 1980-10-31 | 1985-09-26 | 株式会社興人 | シチジンジリン酸コリンの製法 |
CA1188998A (en) * | 1980-11-12 | 1985-06-18 | Stephen R. Ash | System and method for controlling and monitoring blood or biologic fluid flow |
JPS6043079B2 (ja) * | 1980-12-25 | 1985-09-26 | 株式会社興人 | シチジン二リン酸コリンの製造方法 |
IT1177373B (it) * | 1984-12-06 | 1987-08-26 | Bioresearch Spa | Sali della 5'-metiltio-5'-deossiadenosina con acidi solfonici a lunga catena alchilica |
-
1985
- 1985-07-05 IT IT21447/85A patent/IT1188178B/it active
-
1986
- 1986-06-25 DE DE8686108677T patent/DE3678498D1/de not_active Expired - Fee Related
- 1986-06-25 AT AT86108677T patent/ATE62250T1/de not_active IP Right Cessation
- 1986-06-25 EP EP86108677A patent/EP0207436B1/en not_active Expired - Lifetime
- 1986-06-26 US US06/878,697 patent/US4789666A/en not_active Expired - Fee Related
- 1986-07-04 JP JP61156325A patent/JPS6212794A/ja active Granted
Also Published As
Publication number | Publication date |
---|---|
US4789666A (en) | 1988-12-06 |
IT8521447A0 (it) | 1985-07-05 |
EP0207436A2 (en) | 1987-01-07 |
DE3678498D1 (de) | 1991-05-08 |
ATE62250T1 (de) | 1991-04-15 |
JPS6212794A (ja) | 1987-01-21 |
EP0207436A3 (en) | 1988-01-27 |
EP0207436B1 (en) | 1991-04-03 |
JPH0217559B2 (it) | 1990-04-20 |
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