ATE62250T1 - Cytidine-diphosphocholine salze, besonders geeignet fuer oralen gebrauch. - Google Patents

Cytidine-diphosphocholine salze, besonders geeignet fuer oralen gebrauch.

Info

Publication number
ATE62250T1
ATE62250T1 AT86108677T AT86108677T ATE62250T1 AT E62250 T1 ATE62250 T1 AT E62250T1 AT 86108677 T AT86108677 T AT 86108677T AT 86108677 T AT86108677 T AT 86108677T AT E62250 T1 ATE62250 T1 AT E62250T1
Authority
AT
Austria
Prior art keywords
salts
diphosphocholine
cytidine
particularly suitable
oral use
Prior art date
Application number
AT86108677T
Other languages
English (en)
Inventor
Federico Gennari
Original Assignee
Bioresearch Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bioresearch Spa filed Critical Bioresearch Spa
Application granted granted Critical
Publication of ATE62250T1 publication Critical patent/ATE62250T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C07H19/10—Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
AT86108677T 1985-07-05 1986-06-25 Cytidine-diphosphocholine salze, besonders geeignet fuer oralen gebrauch. ATE62250T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT21447/85A IT1188178B (it) 1985-07-05 1985-07-05 Sali della citidin-difospocolina particolarmente idonei per uso orale
EP86108677A EP0207436B1 (de) 1985-07-05 1986-06-25 Cytidine-diphosphocholine Salze, besonders geeignet für oralen Gebrauch

Publications (1)

Publication Number Publication Date
ATE62250T1 true ATE62250T1 (de) 1991-04-15

Family

ID=11181915

Family Applications (1)

Application Number Title Priority Date Filing Date
AT86108677T ATE62250T1 (de) 1985-07-05 1986-06-25 Cytidine-diphosphocholine salze, besonders geeignet fuer oralen gebrauch.

Country Status (6)

Country Link
US (1) US4789666A (de)
EP (1) EP0207436B1 (de)
JP (1) JPS6212794A (de)
AT (1) ATE62250T1 (de)
DE (1) DE3678498D1 (de)
IT (1) IT1188178B (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0408668B1 (de) * 1988-10-27 1994-05-11 Massachusetts Institute Of Technology Verfahren zur Steigerung des Phosphatidylcholins in Vivo
KR0177841B1 (ko) * 1992-01-30 1999-04-01 나까무라 간노스께 시티딘 디인산 콜린의 제조방법
US5482706A (en) * 1992-04-17 1996-01-09 Takeda Chemical Industries, Ltd. Transmucosal therapeutic composition
HUP0101235A3 (en) * 1997-12-24 2002-04-29 Ferrer Int Hyperhydrated citicoline, process for preparing it and use
US7915233B1 (en) 1998-08-31 2011-03-29 Wellstat Therapeutics Corporation Compositions and methods for treatment of mitochondrial diseases
US6472378B2 (en) * 1998-08-31 2002-10-29 Pro-Neuron, Inc. Compositions and methods for treatment of mitochondrial diseases
US7807654B2 (en) * 1998-08-31 2010-10-05 Wellstat Therapeutics Corporation Compositions and methods for treatment of mitochondrial diseases
JP3968347B2 (ja) * 2001-09-05 2007-08-29 ヤマサ醤油株式会社 糖尿病性神経障害用医薬組成物
EP1541154A1 (de) * 2002-07-11 2005-06-15 Yamasa Corporation Medizinische zusammensetzung für arzneimittelbedingte neuropathie
US9572830B2 (en) * 2004-05-13 2017-02-21 Massachusetts Institute Of Technology Uridine effects on dopamine release

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3666748A (en) * 1967-12-18 1972-05-30 Takeda Chemical Industries Ltd Method for production of cytidine (or deoxycytidine)-5{40 -diphosphate choline and intermediates therefor
NL149812B (nl) * 1969-04-24 1976-06-15 Takeda Chemical Industries Ltd Werkwijze ter bereiding van farmaceutische preparaten, alsmede werkwijze ter bereiding van kristallijn cytidine-5'-difosfaat-choline-monohydraat.
JPS5517769B2 (de) * 1972-01-10 1980-05-14
JPS6043078B2 (ja) * 1980-10-31 1985-09-26 株式会社興人 シチジンジリン酸コリンの製法
CA1188998A (en) * 1980-11-12 1985-06-18 Stephen R. Ash System and method for controlling and monitoring blood or biologic fluid flow
JPS6043079B2 (ja) * 1980-12-25 1985-09-26 株式会社興人 シチジン二リン酸コリンの製造方法
IT1177373B (it) * 1984-12-06 1987-08-26 Bioresearch Spa Sali della 5'-metiltio-5'-deossiadenosina con acidi solfonici a lunga catena alchilica

Also Published As

Publication number Publication date
IT1188178B (it) 1988-01-07
JPH0217559B2 (de) 1990-04-20
EP0207436A3 (en) 1988-01-27
US4789666A (en) 1988-12-06
EP0207436A2 (de) 1987-01-07
JPS6212794A (ja) 1987-01-21
IT8521447A0 (it) 1985-07-05
DE3678498D1 (de) 1991-05-08
EP0207436B1 (de) 1991-04-03

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
EEIH Change in the person of patent owner
REN Ceased due to non-payment of the annual fee