AR004691A1 - Nuevos derivados de [3-alcoxi-fenoxi-)-etil]-dialquilamina, una composicion farmaceutica que los comprende, su uso como anestesicos locales y unprocedimiento para su preparacion - Google Patents

Nuevos derivados de [3-alcoxi-fenoxi-)-etil]-dialquilamina, una composicion farmaceutica que los comprende, su uso como anestesicos locales y unprocedimiento para su preparacion

Info

Publication number
AR004691A1
AR004691A1 ARP960104736A ARP960104736A AR004691A1 AR 004691 A1 AR004691 A1 AR 004691A1 AR P960104736 A ARP960104736 A AR P960104736A AR P960104736 A ARP960104736 A AR P960104736A AR 004691 A1 AR004691 A1 AR 004691A1
Authority
AR
Argentina
Prior art keywords
dialkylamine
local anesthetics
preparation
pharmaceutical composition
penoxi
Prior art date
Application number
ARP960104736A
Other languages
English (en)
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SE9503798A external-priority patent/SE9503798D0/xx
Priority claimed from SE9600329A external-priority patent/SE9600329D0/xx
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of AR004691A1 publication Critical patent/AR004691A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C217/06—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted
    • C07C217/14—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring
    • C07C217/18—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted
    • C07C217/20—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted by halogen atoms, by trihalomethyl, nitro or nitroso groups, or by singly-bound oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A61P23/02—Local anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Abstract

Se presentan derivados de [(3-alcoxi-fenoxi)-etil]-dialquilamina de la fórmula (I) en la cual, R1 es alquilo C3-5; y R2 y R3 independientemente sonalquilo C1-3; siempre que cuando tanto R2 como R3 son etilo, R1 no sea n-butilo o n-pentilo; o unasal farmacéuticamente aceptable del mismo, que son deutilidad como anestésicos, especialmente anestéticos locales y específicamente anestésicos locales de aplicación tópica. Se describe además una composiciónfarmacéutica que los contiene, el uso delos mismos y un procedimiento para su su preparación.
ARP960104736A 1995-10-27 1996-10-14 Nuevos derivados de [3-alcoxi-fenoxi-)-etil]-dialquilamina, una composicion farmaceutica que los comprende, su uso como anestesicos locales y unprocedimiento para su preparacion AR004691A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9503798A SE9503798D0 (sv) 1995-10-27 1995-10-27 New anaesthetic componds
SE9600329A SE9600329D0 (sv) 1996-01-30 1996-01-30 New anaesthetic compounds

Publications (1)

Publication Number Publication Date
AR004691A1 true AR004691A1 (es) 1999-03-10

Family

ID=26662410

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP960104736A AR004691A1 (es) 1995-10-27 1996-10-14 Nuevos derivados de [3-alcoxi-fenoxi-)-etil]-dialquilamina, una composicion farmaceutica que los comprende, su uso como anestesicos locales y unprocedimiento para su preparacion

Country Status (30)

Country Link
US (1) US6310252B1 (es)
EP (1) EP0858445B1 (es)
JP (1) JP4101877B2 (es)
KR (1) KR100460652B1 (es)
CN (1) CN1113856C (es)
AR (1) AR004691A1 (es)
AT (1) ATE215061T1 (es)
AU (1) AU704635B2 (es)
BR (1) BR9611234A (es)
CA (1) CA2233489C (es)
CZ (1) CZ124198A3 (es)
DE (1) DE69620213T2 (es)
DK (1) DK0858445T3 (es)
EE (1) EE03963B1 (es)
ES (1) ES2174113T3 (es)
HK (1) HK1009437A1 (es)
HU (1) HUP9901212A3 (es)
IL (1) IL123916A (es)
IS (1) IS1932B (es)
MY (1) MY132329A (es)
NO (1) NO310614B1 (es)
NZ (1) NZ320757A (es)
PL (1) PL186783B1 (es)
PT (1) PT858445E (es)
SI (1) SI0858445T1 (es)
SK (1) SK282757B6 (es)
TR (1) TR199800714T2 (es)
TW (1) TW448142B (es)
UA (1) UA59347C2 (es)
WO (1) WO1997015548A1 (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6432986B2 (en) 1997-07-21 2002-08-13 Bruce H. Levin Compositions, kits, and methods for inhibiting cerebral neurovascular disorders and muscular headaches
US7799337B2 (en) 1997-07-21 2010-09-21 Levin Bruce H Method for directed intranasal administration of a composition
SE9704031D0 (sv) * 1997-11-05 1997-11-05 Astra Ab Novel formulation
SE9704770D0 (sv) * 1997-12-19 1997-12-19 Astra Ab New use
SE9704835D0 (sv) * 1997-12-22 1997-12-22 Astra Ab New compound
SE9704834D0 (sv) * 1997-12-22 1997-12-22 Astra Ab New process
JP2000302737A (ja) * 1999-04-16 2000-10-31 Shiseido Co Ltd 二置換ベンゼン誘導体
US8473062B2 (en) 2008-05-01 2013-06-25 Autonomic Technologies, Inc. Method and device for the treatment of headache
US8412336B2 (en) 2008-12-29 2013-04-02 Autonomic Technologies, Inc. Integrated delivery and visualization tool for a neuromodulation system
US9012477B2 (en) 2009-01-06 2015-04-21 Nuvo Research Inc. Method of treating neuropathic pain
US8494641B2 (en) 2009-04-22 2013-07-23 Autonomic Technologies, Inc. Implantable neurostimulator with integral hermetic electronic enclosure, circuit substrate, monolithic feed-through, lead assembly and anchoring mechanism
US9320908B2 (en) 2009-01-15 2016-04-26 Autonomic Technologies, Inc. Approval per use implanted neurostimulator
US9693976B2 (en) 2010-01-14 2017-07-04 Crescita Therapeutics Inc. Solid-forming local anesthetic formulations for pain control

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1173136A (fr) 1955-11-16 1959-02-20 Rech S Et Tech Appliquees Dérivés tertio-amino-alcoxylés du benzène et leur procédé de préparation
CH380746A (de) 1958-11-06 1964-08-15 Ciba Geigy Verfahren zur Herstellung neuer sekundärer Amine
GB1027611A (en) * 1962-01-04 1966-04-27 May & Baker Ltd Phenoxy- and phenylthio-alkylamines and acid addition salts thereof
US3205136A (en) 1962-12-24 1965-09-07 Smith Kline French Lab Antidepressant phenyloxyalkylamines
DE3233828A1 (de) 1982-09-11 1984-03-15 Basf Ag, 6700 Ludwigshafen Aryloxyalkylamine, verfahren zu ihrer herstellung und ihre verwendung zur bekaempfung unerwuenschten pflanzenwuchses

Also Published As

Publication number Publication date
IL123916A (en) 2001-10-31
MY132329A (en) 2007-10-31
CA2233489A1 (en) 1997-05-01
TR199800714T2 (xx) 1998-07-21
KR19990067083A (ko) 1999-08-16
PL326425A1 (en) 1998-09-14
BR9611234A (pt) 1999-07-13
IS4702A (is) 1998-03-25
SK55398A3 (en) 1999-02-11
JPH11513708A (ja) 1999-11-24
DE69620213T2 (de) 2002-10-17
EE03963B1 (et) 2003-02-17
NO981825L (no) 1998-04-23
NO981825D0 (no) 1998-04-23
CZ124198A3 (cs) 1998-09-16
DE69620213D1 (de) 2002-05-02
ATE215061T1 (de) 2002-04-15
DK0858445T3 (da) 2002-07-01
HUP9901212A3 (en) 2000-02-28
NZ320757A (en) 1999-08-30
JP4101877B2 (ja) 2008-06-18
CN1200723A (zh) 1998-12-02
PT858445E (pt) 2002-09-30
IS1932B (is) 2004-06-16
SK282757B6 (sk) 2002-12-03
EP0858445B1 (en) 2002-03-27
NO310614B1 (no) 2001-07-30
TW448142B (en) 2001-08-01
SI0858445T1 (en) 2002-08-31
HK1009437A1 (en) 1999-06-04
CA2233489C (en) 2005-02-22
UA59347C2 (uk) 2003-09-15
EE9800088A (et) 1998-10-15
HUP9901212A2 (hu) 1999-10-28
EP0858445A1 (en) 1998-08-19
ES2174113T3 (es) 2002-11-01
KR100460652B1 (ko) 2005-04-14
CN1113856C (zh) 2003-07-09
AU704635B2 (en) 1999-04-29
AU7356196A (en) 1997-05-15
US6310252B1 (en) 2001-10-30
WO1997015548A1 (en) 1997-05-01
PL186783B1 (pl) 2004-02-27

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