ES2174113T3 - Nuevos derivados de ((3-alcoxi-fenoxi)-etil)-dialquilamina y su utilizacion como anestesicos locales. - Google Patents

Nuevos derivados de ((3-alcoxi-fenoxi)-etil)-dialquilamina y su utilizacion como anestesicos locales.

Info

Publication number
ES2174113T3
ES2174113T3 ES96935752T ES96935752T ES2174113T3 ES 2174113 T3 ES2174113 T3 ES 2174113T3 ES 96935752 T ES96935752 T ES 96935752T ES 96935752 T ES96935752 T ES 96935752T ES 2174113 T3 ES2174113 T3 ES 2174113T3
Authority
ES
Spain
Prior art keywords
local anesthetics
dialquilamine
fenoxi
alcoxi
etil
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES96935752T
Other languages
English (en)
Inventor
Rune Sandberg
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AstraZeneca AB
Original Assignee
AstraZeneca AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SE9503798A external-priority patent/SE9503798D0/xx
Priority claimed from SE9600329A external-priority patent/SE9600329D0/xx
Application filed by AstraZeneca AB filed Critical AstraZeneca AB
Application granted granted Critical
Publication of ES2174113T3 publication Critical patent/ES2174113T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C217/06—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted
    • C07C217/14—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring
    • C07C217/18—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted
    • C07C217/20—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted by halogen atoms, by trihalomethyl, nitro or nitroso groups, or by singly-bound oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A61P23/02—Local anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Anesthesiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

SE PROPONEN COMPUESTOS DE FORMULA (I), DONDE R 1 REPRESENTA ALQUILO C 3-5 ; Y R 2 Y R 3 REPRESENTAN INDEPENDIENTEMENTE ALQUILO C 1-3 ; CON LA CONDICION DE QUE CUANDO R 2 Y R 3 REPRESENTAN AMBOS ETILO, R 1 NO REPRESENTE N - BUTILO, I - BUTILO O N - PENTILO; O UNA SAL FARMACEUTICAMENTE ACEPTABLE DE ELLOS, QUE SON UTILES COMO ANESTESICOS, EN PARTICULAR ANESTESICOS LOCALES Y ESPECIALMENTE ANESTESICOS LOCALES DE APLICACION TOPICA.
ES96935752T 1995-10-27 1996-10-23 Nuevos derivados de ((3-alcoxi-fenoxi)-etil)-dialquilamina y su utilizacion como anestesicos locales. Expired - Lifetime ES2174113T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9503798A SE9503798D0 (sv) 1995-10-27 1995-10-27 New anaesthetic componds
SE9600329A SE9600329D0 (sv) 1996-01-30 1996-01-30 New anaesthetic compounds

Publications (1)

Publication Number Publication Date
ES2174113T3 true ES2174113T3 (es) 2002-11-01

Family

ID=26662410

Family Applications (1)

Application Number Title Priority Date Filing Date
ES96935752T Expired - Lifetime ES2174113T3 (es) 1995-10-27 1996-10-23 Nuevos derivados de ((3-alcoxi-fenoxi)-etil)-dialquilamina y su utilizacion como anestesicos locales.

Country Status (29)

Country Link
US (1) US6310252B1 (es)
EP (1) EP0858445B1 (es)
JP (1) JP4101877B2 (es)
KR (1) KR100460652B1 (es)
CN (1) CN1113856C (es)
AR (1) AR004691A1 (es)
AT (1) ATE215061T1 (es)
AU (1) AU704635B2 (es)
BR (1) BR9611234A (es)
CA (1) CA2233489C (es)
CZ (1) CZ124198A3 (es)
DE (1) DE69620213T2 (es)
DK (1) DK0858445T3 (es)
EE (1) EE03963B1 (es)
ES (1) ES2174113T3 (es)
HU (1) HUP9901212A3 (es)
IL (1) IL123916A (es)
IS (1) IS1932B (es)
MY (1) MY132329A (es)
NO (1) NO310614B1 (es)
NZ (1) NZ320757A (es)
PL (1) PL186783B1 (es)
PT (1) PT858445E (es)
SI (1) SI0858445T1 (es)
SK (1) SK282757B6 (es)
TR (1) TR199800714T2 (es)
TW (1) TW448142B (es)
UA (1) UA59347C2 (es)
WO (1) WO1997015548A1 (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7799337B2 (en) 1997-07-21 2010-09-21 Levin Bruce H Method for directed intranasal administration of a composition
US6432986B2 (en) 1997-07-21 2002-08-13 Bruce H. Levin Compositions, kits, and methods for inhibiting cerebral neurovascular disorders and muscular headaches
SE9704031D0 (sv) * 1997-11-05 1997-11-05 Astra Ab Novel formulation
SE9704770D0 (sv) * 1997-12-19 1997-12-19 Astra Ab New use
SE9704834D0 (sv) * 1997-12-22 1997-12-22 Astra Ab New process
SE9704835D0 (sv) 1997-12-22 1997-12-22 Astra Ab New compound
JP2000302737A (ja) * 1999-04-16 2000-10-31 Shiseido Co Ltd 二置換ベンゼン誘導体
US8473062B2 (en) 2008-05-01 2013-06-25 Autonomic Technologies, Inc. Method and device for the treatment of headache
US8412336B2 (en) 2008-12-29 2013-04-02 Autonomic Technologies, Inc. Integrated delivery and visualization tool for a neuromodulation system
US9012477B2 (en) 2009-01-06 2015-04-21 Nuvo Research Inc. Method of treating neuropathic pain
US8494641B2 (en) 2009-04-22 2013-07-23 Autonomic Technologies, Inc. Implantable neurostimulator with integral hermetic electronic enclosure, circuit substrate, monolithic feed-through, lead assembly and anchoring mechanism
US9320908B2 (en) 2009-01-15 2016-04-26 Autonomic Technologies, Inc. Approval per use implanted neurostimulator
CN102834096A (zh) 2010-01-14 2012-12-19 卢福研究公司 用于疼痛控制的固态成型局部麻醉制剂

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1173136A (fr) 1955-11-16 1959-02-20 Rech S Et Tech Appliquees Dérivés tertio-amino-alcoxylés du benzène et leur procédé de préparation
CH380746A (de) 1958-11-06 1964-08-15 Ciba Geigy Verfahren zur Herstellung neuer sekundärer Amine
GB1027611A (en) * 1962-01-04 1966-04-27 May & Baker Ltd Phenoxy- and phenylthio-alkylamines and acid addition salts thereof
US3205136A (en) 1962-12-24 1965-09-07 Smith Kline French Lab Antidepressant phenyloxyalkylamines
DE3233828A1 (de) 1982-09-11 1984-03-15 Basf Ag, 6700 Ludwigshafen Aryloxyalkylamine, verfahren zu ihrer herstellung und ihre verwendung zur bekaempfung unerwuenschten pflanzenwuchses

Also Published As

Publication number Publication date
NZ320757A (en) 1999-08-30
DE69620213T2 (de) 2002-10-17
HUP9901212A3 (en) 2000-02-28
WO1997015548A1 (en) 1997-05-01
IS1932B (is) 2004-06-16
SK55398A3 (en) 1999-02-11
TR199800714T2 (xx) 1998-07-21
AR004691A1 (es) 1999-03-10
CN1113856C (zh) 2003-07-09
TW448142B (en) 2001-08-01
EP0858445A1 (en) 1998-08-19
HK1009437A1 (en) 1999-06-04
MY132329A (en) 2007-10-31
AU704635B2 (en) 1999-04-29
IS4702A (is) 1998-03-25
DK0858445T3 (da) 2002-07-01
KR100460652B1 (ko) 2005-04-14
US6310252B1 (en) 2001-10-30
DE69620213D1 (de) 2002-05-02
EE9800088A (et) 1998-10-15
NO310614B1 (no) 2001-07-30
JP4101877B2 (ja) 2008-06-18
NO981825D0 (no) 1998-04-23
CA2233489A1 (en) 1997-05-01
KR19990067083A (ko) 1999-08-16
SI0858445T1 (en) 2002-08-31
EE03963B1 (et) 2003-02-17
ATE215061T1 (de) 2002-04-15
SK282757B6 (sk) 2002-12-03
HUP9901212A2 (hu) 1999-10-28
NO981825L (no) 1998-04-23
IL123916A (en) 2001-10-31
EP0858445B1 (en) 2002-03-27
AU7356196A (en) 1997-05-15
UA59347C2 (uk) 2003-09-15
PT858445E (pt) 2002-09-30
CA2233489C (en) 2005-02-22
CN1200723A (zh) 1998-12-02
JPH11513708A (ja) 1999-11-24
BR9611234A (pt) 1999-07-13
CZ124198A3 (cs) 1998-09-16
PL186783B1 (pl) 2004-02-27
PL326425A1 (en) 1998-09-14

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