HUP0004428A2 - Izopropil-metil-[2-(3-propoxi-fenoxi)-etil]-amin új foszfát sója - Google Patents
Izopropil-metil-[2-(3-propoxi-fenoxi)-etil]-amin új foszfát sójaInfo
- Publication number
- HUP0004428A2 HUP0004428A2 HU0004428A HUP0004428A HUP0004428A2 HU P0004428 A2 HUP0004428 A2 HU P0004428A2 HU 0004428 A HU0004428 A HU 0004428A HU P0004428 A HUP0004428 A HU P0004428A HU P0004428 A2 HUP0004428 A2 HU P0004428A2
- Authority
- HU
- Hungary
- Prior art keywords
- ethyl
- amine
- isopropyl
- methyl
- phosphate salt
- Prior art date
Links
- NUZYBIKIXLKGKN-UHFFFAOYSA-N n-methyl-n-[2-(3-propoxyphenoxy)ethyl]propan-2-amine Chemical compound CCCOC1=CC=CC(OCCN(C)C(C)C)=C1 NUZYBIKIXLKGKN-UHFFFAOYSA-N 0.000 title abstract 3
- 125000002467 phosphate group Chemical class [H]OP(=O)(O[H])O[*] 0.000 title 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 229910000147 aluminium phosphate Inorganic materials 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- -1 monophosphate salt Chemical class 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 150000003013 phosphoric acid derivatives Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C217/06—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted
- C07C217/14—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring
- C07C217/18—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted
- C07C217/20—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted by halogen atoms, by trihalomethyl, nitro or nitroso groups, or by singly-bound oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
- A61P23/02—Local anaesthetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Anesthesiology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
A találmány tárgya az izopropil-metil-[2-(3-propoxi-fenoxi)-etil]-aminúj foszfátsója, az előállítására szolgáló eljárás, az azt tartalmazógyógyszerkészítmény és gyógyászati felhasználása. Az eljárás szerintizopropil-metil-[2-(3-propoxi-fenoxi)-etil]-amin szerves oldószeresoldatához foszforsavat adnak, és az oldatból kikristályosodottmonofoszfátsót izolálják. Ó
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9704835A SE9704835D0 (sv) | 1997-12-22 | 1997-12-22 | New compound |
| PCT/SE1998/002316 WO1999032431A1 (en) | 1997-12-22 | 1998-12-15 | A NOVEL PHOSPHATE SALT OF ISOPROPYL-METHYL-[2-(3-n-PROPOXYPHENOXY)ETHYL]AMINE |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HUP0004428A2 true HUP0004428A2 (hu) | 2002-03-28 |
| HUP0004428A3 HUP0004428A3 (en) | 2002-04-29 |
Family
ID=20409538
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU0004428A HUP0004428A3 (en) | 1997-12-22 | 1998-12-15 | A novel phosphate salt of isopropyl-methyl-[2-(3-n-propoxyphenoxy)ethyl]amine |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US6235792B1 (hu) |
| EP (1) | EP1047663A1 (hu) |
| JP (1) | JP2001526254A (hu) |
| KR (1) | KR20010033407A (hu) |
| CN (1) | CN1280559A (hu) |
| AR (1) | AR017199A1 (hu) |
| AU (1) | AU1989299A (hu) |
| BR (1) | BR9814381A (hu) |
| CA (1) | CA2314989A1 (hu) |
| EE (1) | EE200000384A (hu) |
| HU (1) | HUP0004428A3 (hu) |
| ID (1) | ID26940A (hu) |
| IL (1) | IL136829A0 (hu) |
| IS (1) | IS5544A (hu) |
| NO (1) | NO20003216L (hu) |
| PL (1) | PL341525A1 (hu) |
| SE (1) | SE9704835D0 (hu) |
| SK (1) | SK8062000A3 (hu) |
| TR (1) | TR200002012T2 (hu) |
| TW (1) | TW455590B (hu) |
| WO (1) | WO1999032431A1 (hu) |
| ZA (1) | ZA9811237B (hu) |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH380746A (de) * | 1958-11-06 | 1964-08-15 | Ciba Geigy | Verfahren zur Herstellung neuer sekundärer Amine |
| AR004691A1 (es) * | 1995-10-27 | 1999-03-10 | Astrazeneca Ab | Nuevos derivados de [3-alcoxi-fenoxi-)-etil]-dialquilamina, una composicion farmaceutica que los comprende, su uso como anestesicos locales y unprocedimiento para su preparacion |
-
1997
- 1997-12-22 SE SE9704835A patent/SE9704835D0/xx unknown
-
1998
- 1998-12-08 ZA ZA9811237A patent/ZA9811237B/xx unknown
- 1998-12-09 TW TW087120433A patent/TW455590B/zh not_active IP Right Cessation
- 1998-12-09 AR ARP980106241A patent/AR017199A1/es not_active Application Discontinuation
- 1998-12-15 BR BR9814381-6A patent/BR9814381A/pt not_active IP Right Cessation
- 1998-12-15 AU AU19892/99A patent/AU1989299A/en not_active Abandoned
- 1998-12-15 JP JP2000525368A patent/JP2001526254A/ja active Pending
- 1998-12-15 CN CN98811771A patent/CN1280559A/zh active Pending
- 1998-12-15 TR TR2000/02012T patent/TR200002012T2/xx unknown
- 1998-12-15 WO PCT/SE1998/002316 patent/WO1999032431A1/en not_active Application Discontinuation
- 1998-12-15 US US09/254,420 patent/US6235792B1/en not_active Expired - Fee Related
- 1998-12-15 PL PL98341525A patent/PL341525A1/xx unknown
- 1998-12-15 CA CA002314989A patent/CA2314989A1/en not_active Abandoned
- 1998-12-15 EE EEP200000384A patent/EE200000384A/xx unknown
- 1998-12-15 SK SK806-2000A patent/SK8062000A3/sk unknown
- 1998-12-15 HU HU0004428A patent/HUP0004428A3/hu unknown
- 1998-12-15 EP EP98964600A patent/EP1047663A1/en not_active Ceased
- 1998-12-15 IL IL13682998A patent/IL136829A0/xx unknown
- 1998-12-15 ID IDW20001132A patent/ID26940A/id unknown
- 1998-12-15 KR KR1020007006882A patent/KR20010033407A/ko not_active Application Discontinuation
-
2000
- 2000-06-21 NO NO20003216A patent/NO20003216L/no not_active Application Discontinuation
- 2000-06-21 IS IS5544A patent/IS5544A/is unknown
Also Published As
| Publication number | Publication date |
|---|---|
| SK8062000A3 (en) | 2001-02-12 |
| KR20010033407A (ko) | 2001-04-25 |
| NO20003216D0 (no) | 2000-06-21 |
| ID26940A (id) | 2001-02-22 |
| SE9704835D0 (sv) | 1997-12-22 |
| NO20003216L (no) | 2000-06-21 |
| IL136829A0 (en) | 2001-06-14 |
| US6235792B1 (en) | 2001-05-22 |
| WO1999032431A1 (en) | 1999-07-01 |
| TW455590B (en) | 2001-09-21 |
| CN1280559A (zh) | 2001-01-17 |
| AU1989299A (en) | 1999-07-12 |
| BR9814381A (pt) | 2000-10-10 |
| EP1047663A1 (en) | 2000-11-02 |
| PL341525A1 (en) | 2001-04-23 |
| TR200002012T2 (tr) | 2000-10-23 |
| CA2314989A1 (en) | 1999-07-01 |
| ZA9811237B (en) | 1999-07-19 |
| EE200000384A (et) | 2001-12-17 |
| JP2001526254A (ja) | 2001-12-18 |
| HUP0004428A3 (en) | 2002-04-29 |
| IS5544A (is) | 2000-06-21 |
| AR017199A1 (es) | 2001-08-22 |
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