HUP0004428A2 - Izopropil-metil-[2-(3-propoxi-fenoxi)-etil]-amin új foszfát sója - Google Patents

Izopropil-metil-[2-(3-propoxi-fenoxi)-etil]-amin új foszfát sója

Info

Publication number
HUP0004428A2
HUP0004428A2 HU0004428A HUP0004428A HUP0004428A2 HU P0004428 A2 HUP0004428 A2 HU P0004428A2 HU 0004428 A HU0004428 A HU 0004428A HU P0004428 A HUP0004428 A HU P0004428A HU P0004428 A2 HUP0004428 A2 HU P0004428A2
Authority
HU
Hungary
Prior art keywords
ethyl
amine
isopropyl
methyl
phosphate salt
Prior art date
Application number
HU0004428A
Other languages
English (en)
Inventor
Karol Horvath
Ulf Larsson
Rune Sandberg
Original Assignee
Astrazeneca Ab,
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab, filed Critical Astrazeneca Ab,
Publication of HUP0004428A2 publication Critical patent/HUP0004428A2/hu
Publication of HUP0004428A3 publication Critical patent/HUP0004428A3/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C217/06—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted
    • C07C217/14—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring
    • C07C217/18—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted
    • C07C217/20—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted by halogen atoms, by trihalomethyl, nitro or nitroso groups, or by singly-bound oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A61P23/02—Local anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Anesthesiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

A találmány tárgya az izopropil-metil-[2-(3-propoxi-fenoxi)-etil]-aminúj foszfátsója, az előállítására szolgáló eljárás, az azt tartalmazógyógyszerkészítmény és gyógyászati felhasználása. Az eljárás szerintizopropil-metil-[2-(3-propoxi-fenoxi)-etil]-amin szerves oldószeresoldatához foszforsavat adnak, és az oldatból kikristályosodottmonofoszfátsót izolálják. Ó
HU0004428A 1997-12-22 1998-12-15 A novel phosphate salt of isopropyl-methyl-[2-(3-n-propoxyphenoxy)ethyl]amine HUP0004428A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9704835A SE9704835D0 (sv) 1997-12-22 1997-12-22 New compound
PCT/SE1998/002316 WO1999032431A1 (en) 1997-12-22 1998-12-15 A NOVEL PHOSPHATE SALT OF ISOPROPYL-METHYL-[2-(3-n-PROPOXYPHENOXY)ETHYL]AMINE

Publications (2)

Publication Number Publication Date
HUP0004428A2 true HUP0004428A2 (hu) 2002-03-28
HUP0004428A3 HUP0004428A3 (en) 2002-04-29

Family

ID=20409538

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0004428A HUP0004428A3 (en) 1997-12-22 1998-12-15 A novel phosphate salt of isopropyl-methyl-[2-(3-n-propoxyphenoxy)ethyl]amine

Country Status (22)

Country Link
US (1) US6235792B1 (hu)
EP (1) EP1047663A1 (hu)
JP (1) JP2001526254A (hu)
KR (1) KR20010033407A (hu)
CN (1) CN1280559A (hu)
AR (1) AR017199A1 (hu)
AU (1) AU1989299A (hu)
BR (1) BR9814381A (hu)
CA (1) CA2314989A1 (hu)
EE (1) EE200000384A (hu)
HU (1) HUP0004428A3 (hu)
ID (1) ID26940A (hu)
IL (1) IL136829A0 (hu)
IS (1) IS5544A (hu)
NO (1) NO20003216L (hu)
PL (1) PL341525A1 (hu)
SE (1) SE9704835D0 (hu)
SK (1) SK8062000A3 (hu)
TR (1) TR200002012T2 (hu)
TW (1) TW455590B (hu)
WO (1) WO1999032431A1 (hu)
ZA (1) ZA9811237B (hu)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH380746A (de) * 1958-11-06 1964-08-15 Ciba Geigy Verfahren zur Herstellung neuer sekundärer Amine
AR004691A1 (es) * 1995-10-27 1999-03-10 Astrazeneca Ab Nuevos derivados de [3-alcoxi-fenoxi-)-etil]-dialquilamina, una composicion farmaceutica que los comprende, su uso como anestesicos locales y unprocedimiento para su preparacion

Also Published As

Publication number Publication date
US6235792B1 (en) 2001-05-22
NO20003216D0 (no) 2000-06-21
EE200000384A (et) 2001-12-17
HUP0004428A3 (en) 2002-04-29
AU1989299A (en) 1999-07-12
CN1280559A (zh) 2001-01-17
EP1047663A1 (en) 2000-11-02
IS5544A (is) 2000-06-21
ID26940A (id) 2001-02-22
IL136829A0 (en) 2001-06-14
PL341525A1 (en) 2001-04-23
SK8062000A3 (en) 2001-02-12
TW455590B (en) 2001-09-21
ZA9811237B (en) 1999-07-19
WO1999032431A1 (en) 1999-07-01
BR9814381A (pt) 2000-10-10
NO20003216L (no) 2000-06-21
AR017199A1 (es) 2001-08-22
TR200002012T2 (tr) 2000-10-23
JP2001526254A (ja) 2001-12-18
CA2314989A1 (en) 1999-07-01
KR20010033407A (ko) 2001-04-25
SE9704835D0 (sv) 1997-12-22

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