AR013503A1 - Una combinacion de un inhibidor de la monoamina oxidasa y un antagonista o agonista parcial selectivo de h5-ht(1b), formulacion farmaceutica, usos ymetodo de preparacion - Google Patents
Una combinacion de un inhibidor de la monoamina oxidasa y un antagonista o agonista parcial selectivo de h5-ht(1b), formulacion farmaceutica, usos ymetodo de preparacionInfo
- Publication number
- AR013503A1 AR013503A1 ARP980104635A ARP980104635A AR013503A1 AR 013503 A1 AR013503 A1 AR 013503A1 AR P980104635 A ARP980104635 A AR P980104635A AR P980104635 A ARP980104635 A AR P980104635A AR 013503 A1 AR013503 A1 AR 013503A1
- Authority
- AR
- Argentina
- Prior art keywords
- combination
- antagonist
- selective
- monoamine oxidase
- partial agonist
- Prior art date
Links
- 229940123685 Monoamine oxidase inhibitor Drugs 0.000 title abstract 2
- 239000005557 antagonist Substances 0.000 title abstract 2
- 239000002899 monoamine oxidase inhibitor Substances 0.000 title abstract 2
- 239000004031 partial agonist Substances 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 238000002360 preparation method Methods 0.000 title 1
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 2
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 1
- 125000004191 (C1-C6) alkoxy group Chemical group 0.000 abstract 1
- 125000005913 (C3-C6) cycloalkyl group Chemical group 0.000 abstract 1
- 208000019901 Anxiety disease Diseases 0.000 abstract 1
- 208000019022 Mood disease Diseases 0.000 abstract 1
- -1 R2 is H Chemical group 0.000 abstract 1
- 230000036506 anxiety Effects 0.000 abstract 1
- 125000006367 bivalent amino carbonyl group Chemical group [H]N([*:1])C([*:2])=O 0.000 abstract 1
- 125000006297 carbonyl amino group Chemical group [H]N([*:2])C([*:1])=O 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9703376A SE9703376D0 (sv) | 1997-09-18 | 1997-09-18 | A new combination |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR013503A1 true AR013503A1 (es) | 2000-12-27 |
Family
ID=20408296
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP980104635A AR013503A1 (es) | 1997-09-18 | 1998-09-17 | Una combinacion de un inhibidor de la monoamina oxidasa y un antagonista o agonista parcial selectivo de h5-ht(1b), formulacion farmaceutica, usos ymetodo de preparacion |
Country Status (27)
| Country | Link |
|---|---|
| US (1) | US6159970A (enExample) |
| EP (1) | EP1014986B1 (enExample) |
| JP (1) | JP2001516719A (enExample) |
| KR (2) | KR20010024087A (enExample) |
| CN (1) | CN1278727A (enExample) |
| AR (1) | AR013503A1 (enExample) |
| AT (1) | ATE270889T1 (enExample) |
| AU (1) | AU752719B2 (enExample) |
| BR (1) | BR9812236A (enExample) |
| CA (1) | CA2302204A1 (enExample) |
| DE (1) | DE69825062T2 (enExample) |
| DK (1) | DK1014986T3 (enExample) |
| EE (1) | EE200000146A (enExample) |
| ES (1) | ES2222603T3 (enExample) |
| HU (1) | HUP0100621A2 (enExample) |
| ID (1) | ID25789A (enExample) |
| IL (1) | IL134775A0 (enExample) |
| IS (1) | IS5401A (enExample) |
| MX (1) | MXPA00002616A (enExample) |
| NO (1) | NO20001400L (enExample) |
| PL (1) | PL339368A1 (enExample) |
| PT (1) | PT1014986E (enExample) |
| SE (1) | SE9703376D0 (enExample) |
| SK (1) | SK2832000A3 (enExample) |
| TR (1) | TR200000725T2 (enExample) |
| WO (1) | WO1999013878A1 (enExample) |
| ZA (1) | ZA987804B (enExample) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4957948A (en) * | 1988-05-05 | 1990-09-18 | Interface, Inc. | Biocidal protective coating for heat exchanger coils |
| SE9601110D0 (sv) | 1996-03-22 | 1996-03-22 | Astra Ab | Substituted 1,2,3,4-tetrahydronaphthalene derivatives |
| WO2002066454A1 (fr) * | 2001-02-21 | 2002-08-29 | Sankyo Company, Limited | Derives de chromene |
| ES2323451T7 (es) * | 2001-07-20 | 2011-08-01 | Psychogenics Inc. | Tratamiento para el trastorno de hiperactividad con deficit de atencion. |
| US7732162B2 (en) | 2003-05-05 | 2010-06-08 | Probiodrug Ag | Inhibitors of glutaminyl cyclase for treating neurodegenerative diseases |
| US20090054453A1 (en) * | 2006-03-17 | 2009-02-26 | Lilian Alcaraz | Novel Tetralins as 5-HT6 Modulators |
| US8278345B2 (en) | 2006-11-09 | 2012-10-02 | Probiodrug Ag | Inhibitors of glutaminyl cyclase |
| SI2091948T1 (sl) | 2006-11-30 | 2012-07-31 | Probiodrug Ag | Novi inhibitorji glutaminil ciklaze |
| EA200901140A1 (ru) | 2007-03-01 | 2010-04-30 | Пробиодруг Аг | Новое применение ингибиторов глутаминилциклазы |
| EP2142514B1 (en) | 2007-04-18 | 2014-12-24 | Probiodrug AG | Thiourea derivatives as glutaminyl cyclase inhibitors |
| CN102695546B (zh) | 2009-09-11 | 2014-09-10 | 前体生物药物股份公司 | 作为谷氨酰胺酰环化酶抑制剂的杂环衍生物 |
| WO2011107530A2 (en) | 2010-03-03 | 2011-09-09 | Probiodrug Ag | Novel inhibitors |
| SG183229A1 (en) | 2010-03-10 | 2012-09-27 | Probiodrug Ag | Heterocyclic inhibitors of glutaminyl cyclase (qc, ec 2.3.2.5) |
| EP2560953B1 (en) | 2010-04-21 | 2016-01-06 | Probiodrug AG | Inhibitors of glutaminyl cyclase |
| WO2012123563A1 (en) | 2011-03-16 | 2012-09-20 | Probiodrug Ag | Benz imidazole derivatives as inhibitors of glutaminyl cyclase |
| DK3461819T3 (da) | 2017-09-29 | 2020-08-10 | Probiodrug Ag | Inhibitorer af glutaminylcyklase |
| WO2020183011A1 (en) | 2019-03-14 | 2020-09-17 | Institut Curie | Htr1d inhibitors and uses thereof in the treatment of cancer |
| CN110179988A (zh) * | 2019-07-10 | 2019-08-30 | 王大伟 | 五羟色胺再摄取抑制剂和单胺氧化酶抑制剂联合在制备治疗抑郁症或早泄药物中的应用 |
| EP4633638A1 (en) * | 2022-12-14 | 2025-10-22 | Luminous Mind Inc. | Treatment of psychological factors affecting other medical conditions (pfaomc) |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9119932D0 (en) * | 1991-09-18 | 1991-10-30 | Glaxo Group Ltd | Chemical compounds |
| DE69232003T2 (de) * | 1991-09-18 | 2002-04-25 | Glaxo Group Ltd., Greenford | Benzanilidderivate als 5-HT1D-Antagonisten |
| SE9601110D0 (sv) * | 1996-03-22 | 1996-03-22 | Astra Ab | Substituted 1,2,3,4-tetrahydronaphthalene derivatives |
-
1997
- 1997-09-18 SE SE9703376A patent/SE9703376D0/xx unknown
-
1998
- 1998-08-27 ZA ZA987804A patent/ZA987804B/xx unknown
- 1998-09-09 IL IL13477598A patent/IL134775A0/xx unknown
- 1998-09-09 WO PCT/SE1998/001602 patent/WO1999013878A1/en not_active Ceased
- 1998-09-09 CN CN98811114A patent/CN1278727A/zh active Pending
- 1998-09-09 PT PT98944376T patent/PT1014986E/pt unknown
- 1998-09-09 DK DK98944376T patent/DK1014986T3/da active
- 1998-09-09 KR KR1020007002835A patent/KR20010024087A/ko not_active Ceased
- 1998-09-09 KR KR1020007002830A patent/KR20010024084A/ko not_active Withdrawn
- 1998-09-09 PL PL98339368A patent/PL339368A1/xx unknown
- 1998-09-09 US US09/171,578 patent/US6159970A/en not_active Expired - Fee Related
- 1998-09-09 BR BR9812236-3A patent/BR9812236A/pt not_active IP Right Cessation
- 1998-09-09 CA CA002302204A patent/CA2302204A1/en not_active Abandoned
- 1998-09-09 EP EP98944376A patent/EP1014986B1/en not_active Expired - Lifetime
- 1998-09-09 ID IDW20000522D patent/ID25789A/id unknown
- 1998-09-09 TR TR2000/00725T patent/TR200000725T2/xx unknown
- 1998-09-09 JP JP2000511500A patent/JP2001516719A/ja active Pending
- 1998-09-09 AT AT98944376T patent/ATE270889T1/de not_active IP Right Cessation
- 1998-09-09 HU HU0100621A patent/HUP0100621A2/hu unknown
- 1998-09-09 SK SK283-2000A patent/SK2832000A3/sk unknown
- 1998-09-09 ES ES98944376T patent/ES2222603T3/es not_active Expired - Lifetime
- 1998-09-09 DE DE69825062T patent/DE69825062T2/de not_active Expired - Fee Related
- 1998-09-09 EE EEP200000146A patent/EE200000146A/xx unknown
- 1998-09-09 MX MXPA00002616A patent/MXPA00002616A/es unknown
- 1998-09-09 AU AU91931/98A patent/AU752719B2/en not_active Ceased
- 1998-09-17 AR ARP980104635A patent/AR013503A1/es unknown
-
2000
- 2000-03-14 IS IS5401A patent/IS5401A/is unknown
- 2000-03-17 NO NO20001400A patent/NO20001400L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| US6159970A (en) | 2000-12-12 |
| DE69825062D1 (de) | 2004-08-19 |
| SK2832000A3 (en) | 2000-09-12 |
| CA2302204A1 (en) | 1999-03-25 |
| NO20001400L (no) | 2000-05-05 |
| NO20001400D0 (no) | 2000-03-17 |
| SE9703376D0 (sv) | 1997-09-18 |
| ZA987804B (en) | 1999-03-18 |
| HUP0100621A2 (hu) | 2001-08-28 |
| ES2222603T3 (es) | 2005-02-01 |
| AU752719B2 (en) | 2002-09-26 |
| EP1014986A1 (en) | 2000-07-05 |
| JP2001516719A (ja) | 2001-10-02 |
| MXPA00002616A (es) | 2002-04-24 |
| DK1014986T3 (da) | 2004-10-25 |
| IS5401A (is) | 2000-03-14 |
| EE200000146A (et) | 2001-02-15 |
| CN1278727A (zh) | 2001-01-03 |
| ID25789A (id) | 2000-11-02 |
| ATE270889T1 (de) | 2004-07-15 |
| PT1014986E (pt) | 2004-10-29 |
| EP1014986B1 (en) | 2004-07-14 |
| KR20010024084A (ko) | 2001-03-26 |
| PL339368A1 (en) | 2000-12-18 |
| BR9812236A (pt) | 2000-07-18 |
| KR20010024087A (ko) | 2001-03-26 |
| IL134775A0 (en) | 2001-04-30 |
| TR200000725T2 (tr) | 2000-08-21 |
| DE69825062T2 (de) | 2005-08-25 |
| AU9193198A (en) | 1999-04-05 |
| WO1999013878A1 (en) | 1999-03-25 |
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