DK1014986T3 - Kombination af en inhibitor for monoaminoxidase og en antagonist eller delvis agonist for h5-HT 1 beta - Google Patents
Kombination af en inhibitor for monoaminoxidase og en antagonist eller delvis agonist for h5-HT 1 betaInfo
- Publication number
- DK1014986T3 DK1014986T3 DK98944376T DK98944376T DK1014986T3 DK 1014986 T3 DK1014986 T3 DK 1014986T3 DK 98944376 T DK98944376 T DK 98944376T DK 98944376 T DK98944376 T DK 98944376T DK 1014986 T3 DK1014986 T3 DK 1014986T3
- Authority
- DK
- Denmark
- Prior art keywords
- antagonist
- beta
- inhibitor
- combination
- monoamine oxidase
- Prior art date
Links
- 102000010909 Monoamine Oxidase Human genes 0.000 title 1
- 108010062431 Monoamine oxidase Proteins 0.000 title 1
- 239000005557 antagonist Substances 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
- 239000004031 partial agonist Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Neurology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9703376A SE9703376D0 (sv) | 1997-09-18 | 1997-09-18 | A new combination |
| PCT/SE1998/001602 WO1999013878A1 (en) | 1997-09-18 | 1998-09-09 | A COMBINATION OF A MONOAMINE OXIDASE INHIBITOR AND A h5-HT1B ANTAGONIST OR PARTIAL AGONIST |
| EP98944376A EP1014986B1 (en) | 1997-09-18 | 1998-09-09 | A COMBINATION OF A MONOAMINE OXIDASE INHIBITOR AND A h5-HT 1 BETA ANTAGONIST OR PARTIAL AGONIST |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1014986T3 true DK1014986T3 (da) | 2004-10-25 |
Family
ID=20408296
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK98944376T DK1014986T3 (da) | 1997-09-18 | 1998-09-09 | Kombination af en inhibitor for monoaminoxidase og en antagonist eller delvis agonist for h5-HT 1 beta |
Country Status (27)
| Country | Link |
|---|---|
| US (1) | US6159970A (da) |
| EP (1) | EP1014986B1 (da) |
| JP (1) | JP2001516719A (da) |
| KR (2) | KR20010024087A (da) |
| CN (1) | CN1278727A (da) |
| AR (1) | AR013503A1 (da) |
| AT (1) | ATE270889T1 (da) |
| AU (1) | AU752719B2 (da) |
| BR (1) | BR9812236A (da) |
| CA (1) | CA2302204A1 (da) |
| DE (1) | DE69825062T2 (da) |
| DK (1) | DK1014986T3 (da) |
| EE (1) | EE200000146A (da) |
| ES (1) | ES2222603T3 (da) |
| HU (1) | HUP0100621A2 (da) |
| ID (1) | ID25789A (da) |
| IL (1) | IL134775A0 (da) |
| IS (1) | IS5401A (da) |
| MX (1) | MXPA00002616A (da) |
| NO (1) | NO20001400L (da) |
| PL (1) | PL339368A1 (da) |
| PT (1) | PT1014986E (da) |
| SE (1) | SE9703376D0 (da) |
| SK (1) | SK2832000A3 (da) |
| TR (1) | TR200000725T2 (da) |
| WO (1) | WO1999013878A1 (da) |
| ZA (1) | ZA987804B (da) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4957948A (en) * | 1988-05-05 | 1990-09-18 | Interface, Inc. | Biocidal protective coating for heat exchanger coils |
| SE9601110D0 (sv) | 1996-03-22 | 1996-03-22 | Astra Ab | Substituted 1,2,3,4-tetrahydronaphthalene derivatives |
| WO2002066454A1 (en) * | 2001-02-21 | 2002-08-29 | Sankyo Company, Limited | Chromene derivatives |
| US7504395B2 (en) * | 2001-07-20 | 2009-03-17 | Psychogenics, Inc. | Treatment for attention-deficit hyperactivity disorder |
| US7732162B2 (en) | 2003-05-05 | 2010-06-08 | Probiodrug Ag | Inhibitors of glutaminyl cyclase for treating neurodegenerative diseases |
| US20090054453A1 (en) * | 2006-03-17 | 2009-02-26 | Lilian Alcaraz | Novel Tetralins as 5-HT6 Modulators |
| WO2008055945A1 (en) | 2006-11-09 | 2008-05-15 | Probiodrug Ag | 3-hydr0xy-1,5-dihydr0-pyrr0l-2-one derivatives as inhibitors of glutaminyl cyclase for the treatment of ulcer, cancer and other diseases |
| WO2008065141A1 (en) | 2006-11-30 | 2008-06-05 | Probiodrug Ag | Novel inhibitors of glutaminyl cyclase |
| ZA200905537B (en) | 2007-03-01 | 2010-10-27 | Probiodrug Ag | New use of glutaminyl cyclase inhibitors |
| JP5667440B2 (ja) | 2007-04-18 | 2015-02-12 | プロビオドルグ エージー | グルタミニルシクラーゼ阻害剤としてのチオ尿素誘導体 |
| MX2012002993A (es) | 2009-09-11 | 2012-04-19 | Probiodrug Ag | Derivados heterociclicos como inhibidores de ciclasa glutaminilo. |
| JP6026284B2 (ja) | 2010-03-03 | 2016-11-16 | プロビオドルグ エージー | グルタミニルシクラーゼの阻害剤 |
| MX2012010470A (es) | 2010-03-10 | 2012-10-09 | Probiodrug Ag | Inhibidores heterociclicos d ciclasa de glutaminilo (qc, ec .3 2. 5). |
| US8541596B2 (en) | 2010-04-21 | 2013-09-24 | Probiodrug Ag | Inhibitors |
| WO2012123563A1 (en) | 2011-03-16 | 2012-09-20 | Probiodrug Ag | Benz imidazole derivatives as inhibitors of glutaminyl cyclase |
| EP3461819B1 (en) | 2017-09-29 | 2020-05-27 | Probiodrug AG | Inhibitors of glutaminyl cyclase |
| WO2020183011A1 (en) | 2019-03-14 | 2020-09-17 | Institut Curie | Htr1d inhibitors and uses thereof in the treatment of cancer |
| CN110179988A (zh) * | 2019-07-10 | 2019-08-30 | 王大伟 | 五羟色胺再摄取抑制剂和单胺氧化酶抑制剂联合在制备治疗抑郁症或早泄药物中的应用 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE204262T1 (de) * | 1991-09-18 | 2001-09-15 | Glaxo Group Ltd | Benzanilidderivate als 5-ht1d-antagonisten |
| GB9119932D0 (en) * | 1991-09-18 | 1991-10-30 | Glaxo Group Ltd | Chemical compounds |
| SE9601110D0 (sv) * | 1996-03-22 | 1996-03-22 | Astra Ab | Substituted 1,2,3,4-tetrahydronaphthalene derivatives |
-
1997
- 1997-09-18 SE SE9703376A patent/SE9703376D0/xx unknown
-
1998
- 1998-08-27 ZA ZA987804A patent/ZA987804B/xx unknown
- 1998-09-09 CA CA002302204A patent/CA2302204A1/en not_active Abandoned
- 1998-09-09 ES ES98944376T patent/ES2222603T3/es not_active Expired - Lifetime
- 1998-09-09 BR BR9812236-3A patent/BR9812236A/pt not_active IP Right Cessation
- 1998-09-09 KR KR1020007002835A patent/KR20010024087A/ko active Search and Examination
- 1998-09-09 AU AU91931/98A patent/AU752719B2/en not_active Ceased
- 1998-09-09 MX MXPA00002616A patent/MXPA00002616A/es unknown
- 1998-09-09 HU HU0100621A patent/HUP0100621A2/hu unknown
- 1998-09-09 EE EEP200000146A patent/EE200000146A/xx unknown
- 1998-09-09 DK DK98944376T patent/DK1014986T3/da active
- 1998-09-09 IL IL13477598A patent/IL134775A0/xx unknown
- 1998-09-09 SK SK283-2000A patent/SK2832000A3/sk unknown
- 1998-09-09 AT AT98944376T patent/ATE270889T1/de not_active IP Right Cessation
- 1998-09-09 JP JP2000511500A patent/JP2001516719A/ja active Pending
- 1998-09-09 EP EP98944376A patent/EP1014986B1/en not_active Expired - Lifetime
- 1998-09-09 ID IDW20000522D patent/ID25789A/id unknown
- 1998-09-09 CN CN98811114A patent/CN1278727A/zh active Pending
- 1998-09-09 WO PCT/SE1998/001602 patent/WO1999013878A1/en active IP Right Grant
- 1998-09-09 PT PT98944376T patent/PT1014986E/pt unknown
- 1998-09-09 DE DE69825062T patent/DE69825062T2/de not_active Expired - Fee Related
- 1998-09-09 KR KR1020007002830A patent/KR20010024084A/ko not_active Application Discontinuation
- 1998-09-09 PL PL98339368A patent/PL339368A1/xx unknown
- 1998-09-09 TR TR2000/00725T patent/TR200000725T2/xx unknown
- 1998-09-09 US US09/171,578 patent/US6159970A/en not_active Expired - Fee Related
- 1998-09-17 AR ARP980104635A patent/AR013503A1/es unknown
-
2000
- 2000-03-14 IS IS5401A patent/IS5401A/is unknown
- 2000-03-17 NO NO20001400A patent/NO20001400L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| SK2832000A3 (en) | 2000-09-12 |
| DE69825062D1 (de) | 2004-08-19 |
| PT1014986E (pt) | 2004-10-29 |
| DE69825062T2 (de) | 2005-08-25 |
| SE9703376D0 (sv) | 1997-09-18 |
| EP1014986A1 (en) | 2000-07-05 |
| AR013503A1 (es) | 2000-12-27 |
| JP2001516719A (ja) | 2001-10-02 |
| NO20001400L (no) | 2000-05-05 |
| TR200000725T2 (tr) | 2000-08-21 |
| ID25789A (id) | 2000-11-02 |
| AU9193198A (en) | 1999-04-05 |
| IS5401A (is) | 2000-03-14 |
| ES2222603T3 (es) | 2005-02-01 |
| IL134775A0 (en) | 2001-04-30 |
| EP1014986B1 (en) | 2004-07-14 |
| CA2302204A1 (en) | 1999-03-25 |
| BR9812236A (pt) | 2000-07-18 |
| WO1999013878A1 (en) | 1999-03-25 |
| CN1278727A (zh) | 2001-01-03 |
| AU752719B2 (en) | 2002-09-26 |
| KR20010024084A (ko) | 2001-03-26 |
| KR20010024087A (ko) | 2001-03-26 |
| HUP0100621A2 (hu) | 2001-08-28 |
| ATE270889T1 (de) | 2004-07-15 |
| US6159970A (en) | 2000-12-12 |
| PL339368A1 (en) | 2000-12-18 |
| EE200000146A (et) | 2001-02-15 |
| ZA987804B (en) | 1999-03-18 |
| NO20001400D0 (no) | 2000-03-17 |
| MXPA00002616A (es) | 2002-04-24 |
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