ZA987804B - A combination of a monoamine oxidase inhibitor and a H5-HT1b antagonists or agonist - Google Patents

A combination of a monoamine oxidase inhibitor and a H5-HT1b antagonists or agonist

Info

Publication number
ZA987804B
ZA987804B ZA987804A ZA987804A ZA987804B ZA 987804 B ZA987804 B ZA 987804B ZA 987804 A ZA987804 A ZA 987804A ZA 987804 A ZA987804 A ZA 987804A ZA 987804 B ZA987804 B ZA 987804B
Authority
ZA
South Africa
Prior art keywords
agonist
combination
monoamine oxidase
oxidase inhibitor
ht1b antagonists
Prior art date
Application number
ZA987804A
Other languages
English (en)
Inventor
Stefan Berg
Svante Ross
Seth-Olov Thorberg
Original Assignee
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Ab filed Critical Astra Ab
Publication of ZA987804B publication Critical patent/ZA987804B/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
ZA987804A 1997-09-18 1998-08-27 A combination of a monoamine oxidase inhibitor and a H5-HT1b antagonists or agonist ZA987804B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9703376A SE9703376D0 (sv) 1997-09-18 1997-09-18 A new combination

Publications (1)

Publication Number Publication Date
ZA987804B true ZA987804B (en) 1999-03-18

Family

ID=20408296

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA987804A ZA987804B (en) 1997-09-18 1998-08-27 A combination of a monoamine oxidase inhibitor and a H5-HT1b antagonists or agonist

Country Status (27)

Country Link
US (1) US6159970A (xx)
EP (1) EP1014986B1 (xx)
JP (1) JP2001516719A (xx)
KR (2) KR20010024087A (xx)
CN (1) CN1278727A (xx)
AR (1) AR013503A1 (xx)
AT (1) ATE270889T1 (xx)
AU (1) AU752719B2 (xx)
BR (1) BR9812236A (xx)
CA (1) CA2302204A1 (xx)
DE (1) DE69825062T2 (xx)
DK (1) DK1014986T3 (xx)
EE (1) EE200000146A (xx)
ES (1) ES2222603T3 (xx)
HU (1) HUP0100621A2 (xx)
ID (1) ID25789A (xx)
IL (1) IL134775A0 (xx)
IS (1) IS5401A (xx)
MX (1) MXPA00002616A (xx)
NO (1) NO20001400L (xx)
PL (1) PL339368A1 (xx)
PT (1) PT1014986E (xx)
SE (1) SE9703376D0 (xx)
SK (1) SK2832000A3 (xx)
TR (1) TR200000725T2 (xx)
WO (1) WO1999013878A1 (xx)
ZA (1) ZA987804B (xx)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4957948A (en) * 1988-05-05 1990-09-18 Interface, Inc. Biocidal protective coating for heat exchanger coils
SE9601110D0 (sv) 1996-03-22 1996-03-22 Astra Ab Substituted 1,2,3,4-tetrahydronaphthalene derivatives
WO2002066454A1 (en) * 2001-02-21 2002-08-29 Sankyo Company, Limited Chromene derivatives
US7504395B2 (en) * 2001-07-20 2009-03-17 Psychogenics, Inc. Treatment for attention-deficit hyperactivity disorder
US7732162B2 (en) 2003-05-05 2010-06-08 Probiodrug Ag Inhibitors of glutaminyl cyclase for treating neurodegenerative diseases
US20090054453A1 (en) * 2006-03-17 2009-02-26 Lilian Alcaraz Novel Tetralins as 5-HT6 Modulators
WO2008055945A1 (en) 2006-11-09 2008-05-15 Probiodrug Ag 3-hydr0xy-1,5-dihydr0-pyrr0l-2-one derivatives as inhibitors of glutaminyl cyclase for the treatment of ulcer, cancer and other diseases
WO2008065141A1 (en) 2006-11-30 2008-06-05 Probiodrug Ag Novel inhibitors of glutaminyl cyclase
ZA200905537B (en) 2007-03-01 2010-10-27 Probiodrug Ag New use of glutaminyl cyclase inhibitors
JP5667440B2 (ja) 2007-04-18 2015-02-12 プロビオドルグ エージー グルタミニルシクラーゼ阻害剤としてのチオ尿素誘導体
MX2012002993A (es) 2009-09-11 2012-04-19 Probiodrug Ag Derivados heterociclicos como inhibidores de ciclasa glutaminilo.
JP6026284B2 (ja) 2010-03-03 2016-11-16 プロビオドルグ エージー グルタミニルシクラーゼの阻害剤
MX2012010470A (es) 2010-03-10 2012-10-09 Probiodrug Ag Inhibidores heterociclicos d ciclasa de glutaminilo (qc, ec .3 2. 5).
US8541596B2 (en) 2010-04-21 2013-09-24 Probiodrug Ag Inhibitors
WO2012123563A1 (en) 2011-03-16 2012-09-20 Probiodrug Ag Benz imidazole derivatives as inhibitors of glutaminyl cyclase
EP3461819B1 (en) 2017-09-29 2020-05-27 Probiodrug AG Inhibitors of glutaminyl cyclase
WO2020183011A1 (en) 2019-03-14 2020-09-17 Institut Curie Htr1d inhibitors and uses thereof in the treatment of cancer
CN110179988A (zh) * 2019-07-10 2019-08-30 王大伟 五羟色胺再摄取抑制剂和单胺氧化酶抑制剂联合在制备治疗抑郁症或早泄药物中的应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE204262T1 (de) * 1991-09-18 2001-09-15 Glaxo Group Ltd Benzanilidderivate als 5-ht1d-antagonisten
GB9119932D0 (en) * 1991-09-18 1991-10-30 Glaxo Group Ltd Chemical compounds
SE9601110D0 (sv) * 1996-03-22 1996-03-22 Astra Ab Substituted 1,2,3,4-tetrahydronaphthalene derivatives

Also Published As

Publication number Publication date
SK2832000A3 (en) 2000-09-12
DE69825062D1 (de) 2004-08-19
PT1014986E (pt) 2004-10-29
DE69825062T2 (de) 2005-08-25
SE9703376D0 (sv) 1997-09-18
EP1014986A1 (en) 2000-07-05
AR013503A1 (es) 2000-12-27
JP2001516719A (ja) 2001-10-02
NO20001400L (no) 2000-05-05
TR200000725T2 (tr) 2000-08-21
ID25789A (id) 2000-11-02
AU9193198A (en) 1999-04-05
IS5401A (is) 2000-03-14
ES2222603T3 (es) 2005-02-01
IL134775A0 (en) 2001-04-30
EP1014986B1 (en) 2004-07-14
CA2302204A1 (en) 1999-03-25
BR9812236A (pt) 2000-07-18
WO1999013878A1 (en) 1999-03-25
CN1278727A (zh) 2001-01-03
AU752719B2 (en) 2002-09-26
KR20010024084A (ko) 2001-03-26
DK1014986T3 (da) 2004-10-25
KR20010024087A (ko) 2001-03-26
HUP0100621A2 (hu) 2001-08-28
ATE270889T1 (de) 2004-07-15
US6159970A (en) 2000-12-12
PL339368A1 (en) 2000-12-18
EE200000146A (et) 2001-02-15
NO20001400D0 (no) 2000-03-17
MXPA00002616A (es) 2002-04-24

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