AR012751A1 - Sales de hidrogeno tartrato de (r) -3-n,n-diciclobutilamino-8-fluoro-3,4 -dihidro-2h-1-benzopiran-5-carboxamida, su uso para la fabricacion de medicamentos para tratar trastornos de snc y trastornos medicos relacionados y procedimiento para la fabricacion de dichas sales - Google Patents

Sales de hidrogeno tartrato de (r) -3-n,n-diciclobutilamino-8-fluoro-3,4 -dihidro-2h-1-benzopiran-5-carboxamida, su uso para la fabricacion de medicamentos para tratar trastornos de snc y trastornos medicos relacionados y procedimiento para la fabricacion de dichas sales

Info

Publication number
AR012751A1
AR012751A1 ARP980102434A ARP980102434A AR012751A1 AR 012751 A1 AR012751 A1 AR 012751A1 AR P980102434 A ARP980102434 A AR P980102434A AR P980102434 A ARP980102434 A AR P980102434A AR 012751 A1 AR012751 A1 AR 012751A1
Authority
AR
Argentina
Prior art keywords
manufacture
salts
tartrate
disorders
fluoro
Prior art date
Application number
ARP980102434A
Other languages
English (en)
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of AR012751A1 publication Critical patent/AR012751A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/04—Drugs for disorders of the urinary system for urolithiasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Urology & Nephrology (AREA)
  • Hospice & Palliative Care (AREA)
  • Cardiology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrane Compounds (AREA)

Abstract

Una nueva sal de hidrogeno tartrato de (R)-3-N,N-diciclobutilamino-8-fluoro -3,4-dihidro-2H-1-benzopiran-5-carboxamida, particularmente su (2R; 3R)-tartrato, más particularmente el monohidrato de hidrogeno (2R, 3R) tartrato de (R)-3-N,N-diciclobutilamino-8-fluoro-3,4-dihidro-2H-1 benzopiran-5-carboxamida, los procesos para la fabricacion de dicha sal de tartrato, el uso de la sal en medicina, el uso de la sal de tartrato en la fabricacion deformulaciones farmacéuticas y un método para el tratamiento de los trastornos del SNC por la administracion de la sal de tartrato a un huésped quenecesita dicho tratamiento.
ARP980102434A 1997-05-30 1998-05-26 Sales de hidrogeno tartrato de (r) -3-n,n-diciclobutilamino-8-fluoro-3,4 -dihidro-2h-1-benzopiran-5-carboxamida, su uso para la fabricacion de medicamentos para tratar trastornos de snc y trastornos medicos relacionados y procedimiento para la fabricacion de dichas sales AR012751A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9702066A SE510305C2 (sv) 1997-05-30 1997-05-30 Nytt salt

Publications (1)

Publication Number Publication Date
AR012751A1 true AR012751A1 (es) 2000-11-08

Family

ID=20407187

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP980102434A AR012751A1 (es) 1997-05-30 1998-05-26 Sales de hidrogeno tartrato de (r) -3-n,n-diciclobutilamino-8-fluoro-3,4 -dihidro-2h-1-benzopiran-5-carboxamida, su uso para la fabricacion de medicamentos para tratar trastornos de snc y trastornos medicos relacionados y procedimiento para la fabricacion de dichas sales

Country Status (34)

Country Link
US (2) US6858645B2 (es)
EP (1) EP0984952B1 (es)
JP (1) JP3554338B2 (es)
KR (1) KR20010013127A (es)
CN (1) CN1198814C (es)
AR (1) AR012751A1 (es)
AT (1) ATE228121T1 (es)
AU (1) AU729301B2 (es)
BG (1) BG64051B1 (es)
BR (1) BR9809519A (es)
CA (1) CA2291732C (es)
DE (1) DE69809547T2 (es)
DK (1) DK0984952T3 (es)
EE (1) EE03874B1 (es)
ES (1) ES2187030T3 (es)
HK (1) HK1025575A1 (es)
HU (1) HUP0001878A3 (es)
ID (1) ID23794A (es)
IL (1) IL133234A (es)
IS (1) IS1943B (es)
MY (1) MY117960A (es)
NO (1) NO995853L (es)
NZ (1) NZ501075A (es)
PL (1) PL337181A1 (es)
PT (1) PT984952E (es)
RU (1) RU2193560C2 (es)
SE (1) SE510305C2 (es)
SK (1) SK282755B6 (es)
TR (1) TR199902926T2 (es)
TW (1) TW510899B (es)
UA (1) UA53720C2 (es)
WO (1) WO1998054166A1 (es)
YU (1) YU62499A (es)
ZA (1) ZA984486B (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE0102888D0 (sv) * 2001-08-29 2001-08-29 Astrazeneca Ab New formulation
SE0102887D0 (sv) * 2001-08-29 2001-08-29 Astrazeneca Ab New formulation
SE0102886D0 (sv) * 2001-08-29 2001-08-29 Astrazeneca Ab New formulation
SE0301795D0 (sv) * 2003-06-19 2003-06-19 Astrazeneca Ab New use I
SE0301796D0 (sv) * 2003-06-19 2003-06-19 Astrazeneca Ab New use II
ATE528807T1 (de) * 2006-05-11 2011-10-15 Johnson Controls Saft Advanced Power Solutions Llc Modulares batteriesystem
JP5163931B2 (ja) * 2007-03-08 2013-03-13 株式会社リコー 定着装置及び画像形成装置
EP2065385A1 (en) * 2007-11-28 2009-06-03 Laboratorios SALVAT, S.A. Stable crystalline salt of (R)-3-fluorophenyl-3,4,5-trifluorobenzylcarbamic acid 1-azabiciyclo [2.2.2]oct-3-yl ester
CN103788043B (zh) * 2008-11-28 2016-02-03 中国医学科学院药物研究所 硝克柳胺化合物晶iv型、其制法和其药物组合物与用途
CA2910085C (en) * 2013-04-26 2021-05-25 Sanofi Tartrate salt of 5-chloro-thiophene-2-carboxylic acid [(s)-2-[methyl-3-(2-oxo-pyrrolidin-1-yl)-benzenesulfonylamino]-3-(4-methyl-piperazin-1-yl)-3-oxo-propryl]amide

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5616610A (en) 1989-12-22 1997-04-01 Astra Aktiebolag (R)-5-carbamoyl-8-fluoro-3-N,N-disubstituted-amino-3,4-dihydro-2H-1-benzopyrans
US5420151A (en) 1989-12-22 1995-05-30 Aktiebolaget Astra Chroman derivatives
IT1282705B1 (it) 1996-02-28 1998-03-31 Recordati Chem Pharm Uso di antagonisti del recettore serotoninergico 5-ht|a per il trattamento dell'incontinenza urinaria
US5990114A (en) 1996-02-28 1999-11-23 Recordati, S.A., Chemical And Pharmaceutical Company Use of 5-HT1A receptor antagonists for the treatment of urinary incontinence

Also Published As

Publication number Publication date
JP2002501527A (ja) 2002-01-15
DE69809547D1 (de) 2003-01-02
EE9900549A (et) 2000-06-15
EP0984952B1 (en) 2002-11-20
CA2291732C (en) 2003-12-30
US20030109576A1 (en) 2003-06-12
ES2187030T3 (es) 2003-05-16
DE69809547T2 (de) 2003-08-21
HK1025575A1 (en) 2000-11-17
CA2291732A1 (en) 1998-12-03
KR20010013127A (ko) 2001-02-26
SK159499A3 (en) 2000-10-09
ATE228121T1 (de) 2002-12-15
AU729301B2 (en) 2001-02-01
HUP0001878A2 (hu) 2001-05-28
NO995853D0 (no) 1999-11-29
BG64051B1 (bg) 2003-11-28
AU7792398A (en) 1998-12-30
EP0984952A1 (en) 2000-03-15
SE9702066L (sv) 1998-12-01
US6858645B2 (en) 2005-02-22
IS5270A (is) 1999-11-24
DK0984952T3 (da) 2003-02-24
TR199902926T2 (xx) 2000-03-21
BG103949A (en) 2000-07-31
SK282755B6 (sk) 2002-12-03
WO1998054166A1 (en) 1998-12-03
IS1943B (is) 2004-08-13
NZ501075A (en) 2001-08-31
MY117960A (en) 2004-08-30
PL337181A1 (en) 2000-08-14
TW510899B (en) 2002-11-21
YU62499A (sh) 2002-06-19
US20050085532A1 (en) 2005-04-21
NO995853L (no) 2000-01-31
ID23794A (id) 2000-05-11
ZA984486B (en) 1998-11-30
EE03874B1 (et) 2002-10-15
UA53720C2 (uk) 2003-02-17
SE9702066D0 (sv) 1997-05-30
RU2193560C2 (ru) 2002-11-27
SE510305C2 (sv) 1999-05-10
CN1258290A (zh) 2000-06-28
IL133234A0 (en) 2001-03-19
HUP0001878A3 (en) 2002-04-29
PT984952E (pt) 2003-03-31
CN1198814C (zh) 2005-04-27
BR9809519A (pt) 2000-06-20
IL133234A (en) 2004-05-12
JP3554338B2 (ja) 2004-08-18

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