BR9809519A - Sal, processo para fabricação e uso do mesmo, formulação farmacêutica, e, processo para prevenção ou tratamento de distúrbios cns e perturbações médicas relacionadas - Google Patents

Sal, processo para fabricação e uso do mesmo, formulação farmacêutica, e, processo para prevenção ou tratamento de distúrbios cns e perturbações médicas relacionadas

Info

Publication number
BR9809519A
BR9809519A BR9809519-6A BR9809519A BR9809519A BR 9809519 A BR9809519 A BR 9809519A BR 9809519 A BR9809519 A BR 9809519A BR 9809519 A BR9809519 A BR 9809519A
Authority
BR
Brazil
Prior art keywords
salt
manufacture
treatment
tartrate
disorders
Prior art date
Application number
BR9809519-6A
Other languages
English (en)
Inventor
Hokan Nyqvist
Daniel D Sohn
Original Assignee
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Ab filed Critical Astra Ab
Publication of BR9809519A publication Critical patent/BR9809519A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/04—Drugs for disorders of the urinary system for urolithiasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Urology & Nephrology (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Child & Adolescent Psychology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Nutrition Science (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

"SAL, PROCESSO PARA FABRICAçãO E USO DO MESMO, FORMULAçãO FARMACêUTICA, E, PROCESSO PARA PREVENçãO OU TRATAMENTO DE DISTúRBIOS CNS E PERTURBAçõES MéDICAS RELACIONADAS". Um novo sal, hidrogeno tartarato de (R)-3-N,N- diciclobutilamino-8-fluoro-3,4-diidro-2H-1-benzopiran-5-carboxamida, particularmente o (2R-3R)-tartarato do mesmo, mais particularmente ainda o hidrogeno (2R,3R)-tartarato monoidratado de (R)-3-N, N-diciclobutilamino-8-fluoro-3,4-diidro-2H-1-benzopiran-5-carboxami da, processos para a fabricação do referido sal tartarato, o uso do sal em medicina, o uso do sal tartarato na fabricação de formulações farmacêuticas, e um processo para tratamento de distúrbios CNS pela administração do sal tartarato a um paciente com necessidade de tal tratamento.
BR9809519-6A 1997-05-30 1998-05-15 Sal, processo para fabricação e uso do mesmo, formulação farmacêutica, e, processo para prevenção ou tratamento de distúrbios cns e perturbações médicas relacionadas BR9809519A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9702066A SE510305C2 (sv) 1997-05-30 1997-05-30 Nytt salt
PCT/SE1998/000907 WO1998054166A1 (en) 1997-05-30 1998-05-15 A new salt

Publications (1)

Publication Number Publication Date
BR9809519A true BR9809519A (pt) 2000-06-20

Family

ID=20407187

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9809519-6A BR9809519A (pt) 1997-05-30 1998-05-15 Sal, processo para fabricação e uso do mesmo, formulação farmacêutica, e, processo para prevenção ou tratamento de distúrbios cns e perturbações médicas relacionadas

Country Status (34)

Country Link
US (2) US6858645B2 (pt)
EP (1) EP0984952B1 (pt)
JP (1) JP3554338B2 (pt)
KR (1) KR20010013127A (pt)
CN (1) CN1198814C (pt)
AR (1) AR012751A1 (pt)
AT (1) ATE228121T1 (pt)
AU (1) AU729301B2 (pt)
BG (1) BG64051B1 (pt)
BR (1) BR9809519A (pt)
CA (1) CA2291732C (pt)
DE (1) DE69809547T2 (pt)
DK (1) DK0984952T3 (pt)
EE (1) EE03874B1 (pt)
ES (1) ES2187030T3 (pt)
HK (1) HK1025575A1 (pt)
HU (1) HUP0001878A3 (pt)
ID (1) ID23794A (pt)
IL (1) IL133234A (pt)
IS (1) IS1943B (pt)
MY (1) MY117960A (pt)
NO (1) NO995853L (pt)
NZ (1) NZ501075A (pt)
PL (1) PL337181A1 (pt)
PT (1) PT984952E (pt)
RU (1) RU2193560C2 (pt)
SE (1) SE510305C2 (pt)
SK (1) SK282755B6 (pt)
TR (1) TR199902926T2 (pt)
TW (1) TW510899B (pt)
UA (1) UA53720C2 (pt)
WO (1) WO1998054166A1 (pt)
YU (1) YU62499A (pt)
ZA (1) ZA984486B (pt)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE0102888D0 (sv) * 2001-08-29 2001-08-29 Astrazeneca Ab New formulation
SE0102887D0 (sv) * 2001-08-29 2001-08-29 Astrazeneca Ab New formulation
SE0102886D0 (sv) * 2001-08-29 2001-08-29 Astrazeneca Ab New formulation
SE0301796D0 (sv) * 2003-06-19 2003-06-19 Astrazeneca Ab New use II
SE0301795D0 (sv) * 2003-06-19 2003-06-19 Astrazeneca Ab New use I
EP2022110B1 (en) * 2006-05-11 2011-10-12 Johnson Controls Saft Advanced Power Solutions LLC Modular battery system
JP5163931B2 (ja) * 2007-03-08 2013-03-13 株式会社リコー 定着装置及び画像形成装置
EP2065385A1 (en) * 2007-11-28 2009-06-03 Laboratorios SALVAT, S.A. Stable crystalline salt of (R)-3-fluorophenyl-3,4,5-trifluorobenzylcarbamic acid 1-azabiciyclo [2.2.2]oct-3-yl ester
CN101747305B (zh) * 2008-11-28 2014-06-18 中国医学科学院药物研究所 硝克柳胺化合物晶v型、其制法和其药物组合物与用途
LT2989095T (lt) * 2013-04-26 2019-03-12 Sanofi 5-chlortiofen-2-karboksirūgšties [(s)-2-[metil-3-(2-okso-pirolidin-1-il)-benzensulfonilamino]-3-(4-metilpiperazin-1 -il)-3-oksopropil]amido tartrato druska

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5420151A (en) * 1989-12-22 1995-05-30 Aktiebolaget Astra Chroman derivatives
US5616610A (en) * 1989-12-22 1997-04-01 Astra Aktiebolag (R)-5-carbamoyl-8-fluoro-3-N,N-disubstituted-amino-3,4-dihydro-2H-1-benzopyrans
US5990114A (en) * 1996-02-28 1999-11-23 Recordati, S.A., Chemical And Pharmaceutical Company Use of 5-HT1A receptor antagonists for the treatment of urinary incontinence
IT1282705B1 (it) 1996-02-28 1998-03-31 Recordati Chem Pharm Uso di antagonisti del recettore serotoninergico 5-ht|a per il trattamento dell'incontinenza urinaria

Also Published As

Publication number Publication date
AU7792398A (en) 1998-12-30
SE510305C2 (sv) 1999-05-10
ID23794A (id) 2000-05-11
BG103949A (en) 2000-07-31
SK282755B6 (sk) 2002-12-03
AU729301B2 (en) 2001-02-01
CA2291732C (en) 2003-12-30
SE9702066L (sv) 1998-12-01
US6858645B2 (en) 2005-02-22
EP0984952A1 (en) 2000-03-15
SE9702066D0 (sv) 1997-05-30
EP0984952B1 (en) 2002-11-20
WO1998054166A1 (en) 1998-12-03
SK159499A3 (en) 2000-10-09
KR20010013127A (ko) 2001-02-26
ES2187030T3 (es) 2003-05-16
US20030109576A1 (en) 2003-06-12
AR012751A1 (es) 2000-11-08
IS5270A (is) 1999-11-24
IS1943B (is) 2004-08-13
IL133234A0 (en) 2001-03-19
JP2002501527A (ja) 2002-01-15
CA2291732A1 (en) 1998-12-03
IL133234A (en) 2004-05-12
US20050085532A1 (en) 2005-04-21
NO995853L (no) 2000-01-31
PT984952E (pt) 2003-03-31
HK1025575A1 (en) 2000-11-17
DE69809547T2 (de) 2003-08-21
ATE228121T1 (de) 2002-12-15
CN1258290A (zh) 2000-06-28
EE9900549A (et) 2000-06-15
DE69809547D1 (de) 2003-01-02
TW510899B (en) 2002-11-21
MY117960A (en) 2004-08-30
BG64051B1 (bg) 2003-11-28
JP3554338B2 (ja) 2004-08-18
NO995853D0 (no) 1999-11-29
UA53720C2 (uk) 2003-02-17
YU62499A (sh) 2002-06-19
DK0984952T3 (da) 2003-02-24
HUP0001878A2 (hu) 2001-05-28
PL337181A1 (en) 2000-08-14
TR199902926T2 (xx) 2000-03-21
ZA984486B (en) 1998-11-30
RU2193560C2 (ru) 2002-11-27
NZ501075A (en) 2001-08-31
CN1198814C (zh) 2005-04-27
HUP0001878A3 (en) 2002-04-29
EE03874B1 (et) 2002-10-15

Similar Documents

Publication Publication Date Title
HUP0203325A2 (hu) Biciklusos aminosavak, ezeket tartalmazó gyógyszerkészítmények és alkalmazásuk
BR9908488A (pt) Composição farmacêutica de topiramato
BR0012488A (pt) Composição farmacêutica, métodos para melhorar a taxa de absorção de um ou mais do que um agente farmaceuticamente ativo em mamìferos, para melhorar o inìcio do benefìcio terapêutico de um ou mais do que um agente farmaceuticamente ativo em mamìferos, para inibição de gastroirritação em um mamìfero, e para tratamento de mamìferos necessitando do tratamento proporcionado por um ou mais do que um agente farmaceuticamente ativo, e, processo para preparar uma composição farmacêutica
HK1003978A1 (en) Composition for the treatment of schizophrenia
BR0012136A (pt) Inibidores de reabsorção de norepinefrina altamente seletivos e métodos de uso dos mesmos
AU2002225772A1 (en) Therapeutic agents and methods of use thereof for treating an amyloidogenic disease
BR0214967A (pt) Composto, sal famaceuticamente aceitável, processo para a preparação de um composto, composição farmacêutica, uso de um composto e método de tratar um distúrbio de um paciente
BG101118A (en) Therapeutical compounds
BR9807673A (pt) Processos para tratar asma alérgica e dermatite em um humano e composição farmacêutica.
BR9809519A (pt) Sal, processo para fabricação e uso do mesmo, formulação farmacêutica, e, processo para prevenção ou tratamento de distúrbios cns e perturbações médicas relacionadas
MX9805705A (es) Compuestos biaromaticos, composiciones farmaceuticas y cosmeticas que los contienen y utilizaciones.
BR9814498A (pt) Processo para o tratamento de obesidade em um humano necessitando de tal tratamento, composto, uso do mesmo, produto, e, composição farmacêutica
DK0792160T3 (da) Glial-afledt neurofoisk faktor som et neurobeskyttende middel
GR3015014T3 (en) Compositions for topical administration containing fluticasone propionate and oxiconazole or its salts.
DE69928806D1 (de) (-)-pseudoephedrin als sympathomimetisches arzneimittel
HUP0300863A2 (hu) N-(3,5-diklór-2-metoxi-fenil)-4-metoxi-3-(1-piperazinil)-benzolszulfonamid, eljárás elżállítására és a vegyületet tartalmazó gyógyszerkészítmény
BR9506748A (pt) Compostos preparação farmacêutica utilização de um composto e processos para o tratamento de um indivíduo sofrendo de dor e para a preparação de um composto
BR0017329A (pt) Formulção farmacêutica de um medicamento, uso de melatonina na fabricação de um medicamento, e, método para prevenção ou tratamento de sintomas de discinesia tardia em um paciente usanto tal medicamento
RU94041028A (ru) Применение производных мелатонина для лечения десинхронизационных нарушений, фармацевтическая композиция
BR9508021A (pt) Composição farmacêutica para o tratamento de distúrbios esquizofrênicos, uso de um agente imunossupressor, e, processo de tratamento de um paciente esquizofrênico
NZ303993A (en) Pharmaceutical compositions containing aminotetralin derivatives for treating cardiac disorders
BR0212167A (pt) Forma de dosagem oral de liberação prolongada, uso da mesma, método para a prevenção e/ou tratamento de distúrbios e perturbações médicas, e, processo para a fabricação de uma forma de dosagem de liberação prolongada
IL164317A0 (en) Statin therapy for enhancing cognitive maintenance
HUP0402062A2 (hu) Alkanoil-L-karnitin alkalmazása merevedési zavar kezelésére és ezt tartalmazó gyógyszerkészítmények
TW374085B (en) Novel piperidine derivatives, their preparation, pharmaceutical formulation and medical use

Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 9A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1912 DE 28/08/2007.