AR009133A1 - Un procedimiento para preparar 5,6-dimetil-2-(4-fluorofenilamino)-4-(1-metil- 1,2,3,4-tetrahidroisoquinolin-2-il)pirimidina, procedimientos para preparar una 4-halogeno-2-(4-fluorofenilamino)-5,6-dimetilpirimidina y un derivado de pirimidina util como intermediario - Google Patents
Un procedimiento para preparar 5,6-dimetil-2-(4-fluorofenilamino)-4-(1-metil- 1,2,3,4-tetrahidroisoquinolin-2-il)pirimidina, procedimientos para preparar una 4-halogeno-2-(4-fluorofenilamino)-5,6-dimetilpirimidina y un derivado de pirimidina util como intermediarioInfo
- Publication number
- AR009133A1 AR009133A1 ARP970104978A ARP970104978A AR009133A1 AR 009133 A1 AR009133 A1 AR 009133A1 AR P970104978 A ARP970104978 A AR P970104978A AR P970104978 A ARP970104978 A AR P970104978A AR 009133 A1 AR009133 A1 AR 009133A1
- Authority
- AR
- Argentina
- Prior art keywords
- pirimidine
- dimethyl
- fluorophenylamine
- preparing
- methyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/42—One nitrogen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR1019960049382A KR100209587B1 (ko) | 1996-10-29 | 1996-10-29 | 피리미딘 유도체의 제조방법 |
KR1019960049380A KR0185292B1 (ko) | 1996-10-29 | 1996-10-29 | (s)-피리미딘 유도체의 제조방법 |
KR1019960049381A KR100193080B1 (ko) | 1996-10-29 | 1996-10-29 | (r)-피리미딘 유도체의 제조방법 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR009133A1 true AR009133A1 (es) | 2000-03-08 |
Family
ID=27349413
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP970104978A AR009133A1 (es) | 1996-10-29 | 1997-10-28 | Un procedimiento para preparar 5,6-dimetil-2-(4-fluorofenilamino)-4-(1-metil- 1,2,3,4-tetrahidroisoquinolin-2-il)pirimidina, procedimientos para preparar una 4-halogeno-2-(4-fluorofenilamino)-5,6-dimetilpirimidina y un derivado de pirimidina util como intermediario |
Country Status (5)
Country | Link |
---|---|
AR (1) | AR009133A1 (pt) |
BR (1) | BR9712392A (pt) |
HU (1) | HU226752B1 (pt) |
TR (1) | TR199900943T2 (pt) |
WO (1) | WO1998018784A1 (pt) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR100272471B1 (ko) * | 1998-11-17 | 2000-11-15 | 김선진 | 신규의 피리미딘 유도체 및 그의 제조방법 |
US6852739B1 (en) | 1999-02-26 | 2005-02-08 | Nitromed Inc. | Methods using proton pump inhibitors and nitric oxide donors |
GB0110338D0 (en) * | 2001-04-27 | 2001-06-20 | Sb Pharmco Inc | Novel processes |
JP4634144B2 (ja) | 2002-08-01 | 2011-02-16 | ニコックス エスエー | ニトロソ化プロトンポンプ阻害剤、組成物および使用方法 |
US7776873B2 (en) * | 2005-12-01 | 2010-08-17 | Yuhan Corporation | Method for treating damage to gastric mucosa |
PL2007362T3 (pl) | 2006-04-04 | 2019-02-28 | Kg Acquisition Llc | Doustne postacie leku obejmujące czynnik przeciwpłytkowy i inhibitor kwasu |
CN102993173B (zh) * | 2012-12-28 | 2014-09-03 | 山东大学 | 洛氟普啶的制备方法 |
CN105669642B (zh) * | 2014-11-19 | 2020-06-09 | 江苏天士力帝益药业有限公司 | 一种盐酸洛氟普啶的制备方法 |
CN105601611A (zh) * | 2014-11-19 | 2016-05-25 | 江苏天士力帝益药业有限公司 | 一种盐酸洛氟普啶多晶型物及其制备方法 |
CN107759562B (zh) * | 2016-08-21 | 2020-10-23 | 常州四药制药有限公司 | 一种盐酸洛氟普啶的制备方法 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1182584A (en) * | 1966-03-31 | 1970-02-25 | Ici Ltd | Pyrimidine derivates and the use thereof as fungicides |
DE59010042D1 (de) * | 1989-03-22 | 1996-02-22 | Ciba Geigy Ag | Schädlingsbekämpfungsmittel |
KR0144833B1 (ko) * | 1992-12-28 | 1998-07-15 | 김태훈 | 신규의 퀴나졸린 유도체 및 그의 제조방법 |
DE69530989T2 (de) * | 1994-08-13 | 2004-05-19 | Yuhan Corp. | Neue pyrimidinderivate und verfahren zu ihrer herstellung |
-
1997
- 1997-10-27 HU HU9903520A patent/HU226752B1/hu not_active IP Right Cessation
- 1997-10-27 BR BR9712392-7A patent/BR9712392A/pt not_active IP Right Cessation
- 1997-10-27 WO PCT/KR1997/000204 patent/WO1998018784A1/en active Application Filing
- 1997-10-27 TR TR1999/00943T patent/TR199900943T2/xx unknown
- 1997-10-28 AR ARP970104978A patent/AR009133A1/es active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
BR9712392A (pt) | 2000-01-25 |
TR199900943T2 (xx) | 1999-12-21 |
HUP9903520A1 (hu) | 2000-05-28 |
HU226752B1 (en) | 2009-09-28 |
HUP9903520A3 (en) | 2002-01-28 |
WO1998018784A1 (en) | 1998-05-07 |
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