ES2001676A6 - Procedimiento para la preparacion de derivados propionamidinos - Google Patents
Procedimiento para la preparacion de derivados propionamidinosInfo
- Publication number
- ES2001676A6 ES2001676A6 ES8601789A ES8601789A ES2001676A6 ES 2001676 A6 ES2001676 A6 ES 2001676A6 ES 8601789 A ES8601789 A ES 8601789A ES 8601789 A ES8601789 A ES 8601789A ES 2001676 A6 ES2001676 A6 ES 2001676A6
- Authority
- ES
- Spain
- Prior art keywords
- propionamidine
- derivatives
- propionamidine derivatives
- famotidine
- chem
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C303/00—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
- C07C303/34—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of amides of sulfuric acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/44—Acylated amino or imino radicals
- C07D277/48—Acylated amino or imino radicals by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof, e.g. carbonylguanidines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C257/00—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines
- C07C257/10—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. amidines
- C07C257/14—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. amidines having carbon atoms of amidino groups bound to acyclic carbon atoms
Abstract
PROCEDIMIENTO PARA LA PREPARACION DE DERIVADOS PROPIOANIMIDINOS. LA INVENCION SE RELACIONA CON UN PROCEDIMIENTO DE PREPARACION DE NUEVOS DERIVADOS PROPIONAMIDINOS, DE FORMULA GENERAL (I), EN LA QUE X ES HALOGENO. DE ACUERDO CON LA INVENCION SE PREPARAN COMPUESTOS COMPUESTOS DE FORMULA (I) HACIENDO REACCIONAR UN 3-HALOPROPIONITRILO DE FORMULA (III), EN LA QUE X ES COMO SE DEFINE ANTERIORMENTE, CON UNA SULFAMIDA DE FORMULA (II) EN PRESENCIA DE HALURO DE HIDROGENO. LOS NUEVOS COMPUESTOS SON UTILES PRODUCTOS INTERMEDIOS EN LA PREPARACION DE FAMOTIDINA N-SULFAMIL-3-(2-GUANIDINO-TIAZOL-4-IL-METILTIO)PROPIONAMIDINA, AGENTE ANTI-ULCEROSO QUE PROPORCIONA EXCELENTES RESULTADOS EN EL TRATAMIENTO DE ULCERACIONES GASTRICAS E INTESTINALES.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HU853423A HU193608B (en) | 1985-09-11 | 1985-09-11 | Process for production of new dervatives of n-sulphanol-propion-amidine |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2001676A6 true ES2001676A6 (es) | 1988-06-01 |
Family
ID=10963966
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES8601789A Expired ES2001676A6 (es) | 1985-09-11 | 1986-09-11 | Procedimiento para la preparacion de derivados propionamidinos |
Country Status (14)
Country | Link |
---|---|
US (1) | US4731479A (es) |
EP (1) | EP0215639B1 (es) |
JP (1) | JPS6261966A (es) |
KR (1) | KR910003338B1 (es) |
AT (1) | AT386407B (es) |
AU (1) | AU586700B2 (es) |
BE (1) | BE905408A (es) |
CA (1) | CA1266277A (es) |
DE (1) | DE3673732D1 (es) |
DK (1) | DK169621B1 (es) |
ES (1) | ES2001676A6 (es) |
GR (1) | GR862198B (es) |
HU (1) | HU193608B (es) |
PT (1) | PT83347B (es) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HU194845B (en) * | 1985-09-11 | 1988-03-28 | Richter Gedeon Vegyeszet | Process for production of n-sulphamil-3-/2-guanidintiazolil-4-methil-tio/-propion-amidin |
HU193608B (en) * | 1985-09-11 | 1987-11-30 | Richter Gedeon Vegyeszet | Process for production of new dervatives of n-sulphanol-propion-amidine |
ES2008810A6 (es) * | 1988-07-18 | 1989-08-01 | Marga Investigacion | Procedimiento de preparacion de derivados de n-sulfamil-propionamidina. |
US5068405A (en) * | 1990-07-06 | 1991-11-26 | Delmar Chemicals Inc. | Famotidine intermediates and their preparation |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3121084A (en) * | 1962-09-17 | 1964-02-11 | Du Pont | Selected n, n, n'-trisubstituted amidines and their preparation by reaction of compounds with-nh2 groups with amide acetals |
DE1234208B (de) * | 1965-11-23 | 1967-02-16 | Basf Ag | Verfahren zur Herstellung von N, N'-disubstituierten Amidinen |
US4496736A (en) * | 1981-06-23 | 1985-01-29 | Bayer Aktiengesellschaft | Process for the preparation of carboxylic acids and N-tert.-alkylamines |
US4496737A (en) * | 1982-09-27 | 1985-01-29 | Merck & Co., Inc. | Process for preparing sulfamylamidine antisecretory agents |
GB8419223D0 (en) * | 1984-07-27 | 1984-08-30 | Hoechst Uk Ltd | Sulphamoylguanidine derivatives |
HU193608B (en) * | 1985-09-11 | 1987-11-30 | Richter Gedeon Vegyeszet | Process for production of new dervatives of n-sulphanol-propion-amidine |
-
1985
- 1985-09-11 HU HU853423A patent/HU193608B/hu unknown
-
1986
- 1986-08-22 CA CA000516618A patent/CA1266277A/en not_active Expired - Lifetime
- 1986-08-25 GR GR862198A patent/GR862198B/el unknown
- 1986-09-08 KR KR1019860007507A patent/KR910003338B1/ko not_active IP Right Cessation
- 1986-09-09 JP JP61210816A patent/JPS6261966A/ja active Granted
- 1986-09-10 AT AT0243386A patent/AT386407B/de not_active IP Right Cessation
- 1986-09-10 DE DE8686306988T patent/DE3673732D1/de not_active Expired - Lifetime
- 1986-09-10 AU AU62568/86A patent/AU586700B2/en not_active Expired
- 1986-09-10 BE BE0/217143A patent/BE905408A/fr not_active IP Right Cessation
- 1986-09-10 US US06/905,833 patent/US4731479A/en not_active Expired - Lifetime
- 1986-09-10 DK DK434486A patent/DK169621B1/da not_active IP Right Cessation
- 1986-09-10 EP EP86306988A patent/EP0215639B1/en not_active Expired - Lifetime
- 1986-09-10 PT PT83347A patent/PT83347B/pt unknown
- 1986-09-11 ES ES8601789A patent/ES2001676A6/es not_active Expired
Also Published As
Publication number | Publication date |
---|---|
AU586700B2 (en) | 1989-07-20 |
JPS6261966A (ja) | 1987-03-18 |
CA1266277A (en) | 1990-02-27 |
KR870003066A (ko) | 1987-04-14 |
ATA243386A (de) | 1988-01-15 |
DK434486D0 (da) | 1986-09-10 |
EP0215639A2 (en) | 1987-03-25 |
BE905408A (fr) | 1986-12-31 |
AU6256886A (en) | 1987-03-12 |
PT83347A (pt) | 1986-10-01 |
DE3673732D1 (de) | 1990-10-04 |
US4731479A (en) | 1988-03-15 |
JPH0512342B2 (es) | 1993-02-17 |
AT386407B (de) | 1988-08-25 |
GR862198B (en) | 1986-10-31 |
DK434486A (da) | 1987-03-12 |
EP0215639A3 (en) | 1988-01-07 |
EP0215639B1 (en) | 1990-08-29 |
HU193608B (en) | 1987-11-30 |
PT83347B (pt) | 1988-07-29 |
DK169621B1 (da) | 1994-12-27 |
KR910003338B1 (ko) | 1991-05-27 |
HUT41720A (en) | 1987-05-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
SA6 | Expiration date (snapshot 920101) |
Free format text: 2006-09-11 |
|
FD1A | Patent lapsed |
Effective date: 20100528 |