AR006583A1 - Una composición farmacéutica - Google Patents
Una composición farmacéuticaInfo
- Publication number
- AR006583A1 AR006583A1 ARP970101419A ARP970101419A AR006583A1 AR 006583 A1 AR006583 A1 AR 006583A1 AR P970101419 A ARP970101419 A AR P970101419A AR P970101419 A ARP970101419 A AR P970101419A AR 006583 A1 AR006583 A1 AR 006583A1
- Authority
- AR
- Argentina
- Prior art keywords
- composition
- pharmaceutical composition
- salt
- mycophenolate
- immunosuppression
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A61K38/13—Cyclosporins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4891—Coated capsules; Multilayered drug free capsule shells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Virology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Transplantation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
Composición farmacéutica que comprende una sal de mcofenolato, estando la composición adaptada para liberar micofenolato en la parte superior del tractointestinal. Particulamente dicha composición comprende una sal de micofenolato farmacéuticamente aceptable con revestimiento entérico. También proporciona eluso de dicha composición farmacéutica en la preparación de un medicamento para inmunosupresión, particularmente para la prevención de rechazo de trasplante dehaloinjerto o xenoinjerto,na tivo o transgénico de órgano, tejido o de células; para el tratamiento o prevención de enfermedades mediadas por el sistema inmuney/o enfermedades inflamatorias. Asimismo proporciona un método para inmunosuprimir a un sujeto, el cualcomp rende administrar una cantidadterapéuticamente efectiva de dicha sal de micofenolato farmacéuticamente aceptable, con revestimiento entérico o dicha composición a un sujeto ennecesidad de inmunosupresión, opcionalmente con laadministración si multánea o separada de otro inmunosupresor.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9607564.3A GB9607564D0 (en) | 1996-04-12 | 1996-04-12 | Organic compounds |
GBGB9622028.0A GB9622028D0 (en) | 1996-10-24 | 1996-10-24 | Organic compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
AR006583A1 true AR006583A1 (es) | 1999-09-08 |
Family
ID=26309105
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP970101419A AR006583A1 (es) | 1996-04-12 | 1997-04-10 | Una composición farmacéutica |
ARP070100839A AR059693A2 (es) | 1996-04-12 | 2007-03-01 | Una composicion farmaceutica de micofenolato y su uso |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP070100839A AR059693A2 (es) | 1996-04-12 | 2007-03-01 | Una composicion farmaceutica de micofenolato y su uso |
Country Status (34)
Country | Link |
---|---|
US (3) | US6025391A (es) |
EP (2) | EP0892640B1 (es) |
JP (2) | JP3779732B2 (es) |
CN (1) | CN1104238C (es) |
AR (2) | AR006583A1 (es) |
AT (2) | ATE259228T1 (es) |
AU (1) | AU725388B2 (es) |
BE (1) | BE1010963A3 (es) |
BR (1) | BR9708624A (es) |
CO (1) | CO4900024A1 (es) |
CY (1) | CY2243B1 (es) |
CZ (1) | CZ291811B6 (es) |
DE (4) | DE69727559T2 (es) |
DK (1) | DK0892640T3 (es) |
ES (2) | ES2216141T3 (es) |
FR (1) | FR2747920B1 (es) |
GB (1) | GB2326339B (es) |
GR (1) | GR1002893B (es) |
HK (2) | HK1016490A1 (es) |
HU (1) | HU224919B1 (es) |
ID (1) | ID18663A (es) |
IE (1) | IE970267A1 (es) |
IL (1) | IL126431A (es) |
IT (1) | IT1297045B1 (es) |
LU (1) | LU91094I2 (es) |
MY (1) | MY119049A (es) |
NL (1) | NL300157I2 (es) |
NO (2) | NO322891B1 (es) |
NZ (1) | NZ332117A (es) |
PT (1) | PT892640E (es) |
RU (2) | RU2203659C2 (es) |
TR (1) | TR199802056T2 (es) |
TW (1) | TW457098B (es) |
WO (1) | WO1997038689A2 (es) |
Families Citing this family (47)
Publication number | Priority date | Publication date | Assignee | Title |
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DE60044717D1 (de) | 1999-05-10 | 2010-09-02 | Paolo Brenner | Kombination von immunsuppressiven substanzen zur behandlung oder vorbeugung von transplantat abstossungen |
US20030050692A1 (en) * | 2000-12-22 | 2003-03-13 | Avantec Vascular Corporation | Delivery of therapeutic capable agents |
GB0124953D0 (en) * | 2001-10-17 | 2001-12-05 | Novartis Ag | Organic Compounds |
CA2461730C (en) * | 2001-10-19 | 2012-05-15 | Isotechnika Inc. | Novel cyclosporin analog microemulsion preconcentrates |
GB0301259D0 (en) | 2003-01-20 | 2003-02-19 | Novartis Ag | Organic compounds |
GB0314553D0 (en) * | 2003-06-21 | 2003-07-30 | Weatherford Lamb | Electric submersible pumps |
US8993599B2 (en) * | 2003-07-18 | 2015-03-31 | Santarus, Inc. | Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them |
AR045957A1 (es) * | 2003-10-03 | 2005-11-16 | Novartis Ag | Composicion farmaceutica y combinacion |
DE602005009677D1 (de) * | 2004-03-22 | 2008-10-23 | Solvay Pharm Gmbh | Orale pharmazeutische zusammensetzungen von produkten mit lipase, insbesondere von pankreatin, mit tensiden |
MXPA06005659A (es) * | 2004-04-26 | 2007-04-10 | Teva Gyogyszergyar Zartkoruen | Proceso para preparacion de acido micofenolico y derivados de ester del mismo. |
US7358247B2 (en) | 2004-04-27 | 2008-04-15 | TEVA Gyógyszergyár Zártköruen Muködö Részvénytársaság | Mycophenolate mofetil impurity |
JP2008506783A (ja) | 2004-07-20 | 2008-03-06 | テバ ジョジセルジャール ザ−トケルエン ムケド レ−スベニュタ−ルシャシャ−グ | ミコフェノール酸ナトリウムの結晶形の調製方法 |
GB0419355D0 (en) * | 2004-08-31 | 2004-09-29 | Novartis Ag | Organic compounds |
EP1917010A2 (en) * | 2005-02-08 | 2008-05-07 | Aspreva Pharmaceuticals SA | Compositions and methods for treating vascular, autoimmune and inflammatory diseases |
US20060235009A1 (en) * | 2005-02-08 | 2006-10-19 | Richard Glickman | Treatment of vascular, autoimmune and inflammatory diseases using low dosages of IMPDH inhibitors |
BRPI0614914A2 (pt) | 2005-07-29 | 2011-04-19 | Solvay Pharm Gmbh | processos para a fabricação de pó de pancreatina esterilizada |
US9198871B2 (en) * | 2005-08-15 | 2015-12-01 | Abbott Products Gmbh | Delayed release pancreatin compositions |
US11266607B2 (en) | 2005-08-15 | 2022-03-08 | AbbVie Pharmaceuticals GmbH | Process for the manufacture and use of pancreatin micropellet cores |
CN1985994B (zh) * | 2005-12-19 | 2011-01-12 | 康泰乐(北京)医药科技发展有限公司 | 改进的包含霉酚酸盐的包有肠溶衣的药物组合物 |
CA2640283A1 (en) * | 2006-02-13 | 2007-08-23 | Novartis Ag | High dosage of mycophenolic acid (mpa) |
JP2007230948A (ja) * | 2006-03-02 | 2007-09-13 | Univ Meijo | 腸溶性化硬カプセル |
US10072256B2 (en) * | 2006-05-22 | 2018-09-11 | Abbott Products Gmbh | Process for separating and determining the viral load in a pancreatin sample |
US20080009050A1 (en) * | 2006-06-29 | 2008-01-10 | Zdenek Pokluda | Regulation of acid metabolite production |
US20080182998A1 (en) * | 2007-01-25 | 2008-07-31 | Apotex Fermentation Inc. | Novel crystalline mycophenolate sodium polymorph and processes to manufacture same |
US20080176937A1 (en) * | 2007-01-23 | 2008-07-24 | Apotex Fermentation Inc. | Novel crystalline mycophenolate sodium polymorph and processes to manufacture same |
MX2008015797A (es) * | 2007-04-11 | 2009-03-06 | Teva Gyogyszergyar Zartkoeruen | Metodo para reducir el nivel de impurezas en la fermentacion del acido micofenolico. |
MX2010001711A (es) * | 2007-08-13 | 2010-03-11 | Panacea Biotec Ltd | Composiciones de liberacion extendida que comprenden micofenolato sodico y procedimientos de las mismas. |
US20090130063A1 (en) * | 2007-11-15 | 2009-05-21 | Solvay Pharmaceuticals Gmbh | Process for separating and determining the viral load in a pancreatin sample |
JP2011527339A (ja) * | 2008-07-09 | 2011-10-27 | アスプレバ インターナショナル リミテッド | 眼障害を処置するためのミコフェノール酸ナトリウムのpH特異的な溶液 |
US20110086102A1 (en) * | 2009-10-13 | 2011-04-14 | Teva Pharmaceutical Industries Ltd. | Delayed release compositions |
EP2488173A1 (en) * | 2009-10-13 | 2012-08-22 | Teva Pharmaceutical Industries Ltd. | Delayed release compositions |
WO2011051967A2 (en) * | 2009-10-23 | 2011-05-05 | Alkem Laboratories Ltd | Pharmaceutical compositions comprising mycophenolate and processes for preparing thereof |
CN103880800A (zh) * | 2010-11-16 | 2014-06-25 | 北京京卫信康医药科技发展有限公司 | 麦考酚酸钠的新晶型及其制备方法 |
CN103880799A (zh) * | 2010-11-16 | 2014-06-25 | 北京京卫信康医药科技发展有限公司 | 麦考酚酸钠的新晶型及其制备方法 |
GB201100786D0 (en) | 2011-01-18 | 2011-03-02 | Ems Sa | Pharmaceutical compositions of immunosuppressants |
WO2013041205A1 (de) | 2011-09-19 | 2013-03-28 | Pyxirion Pharma Gmbh | Neue therapeutische konzepte zur behandlung von gefässerkrankungen |
ES2683355T3 (es) | 2013-03-14 | 2018-09-26 | Alkermes Pharma Ireland Limited | Profármacos de fumaratos y su uso en el tratamiento de diversas enfermedades |
US8669281B1 (en) | 2013-03-14 | 2014-03-11 | Alkermes Pharma Ireland Limited | Prodrugs of fumarates and their use in treating various diseases |
WO2014167442A1 (en) | 2013-03-26 | 2014-10-16 | Wockhardt Limited | Pharmaceutical compositions comprising mycophenolic acid or salts thereof |
EP3091974B1 (en) | 2014-01-06 | 2020-04-01 | Shield TX (UK) Limited | Dosage regimen of ferric trimaltol |
NZ723269A (en) | 2014-02-24 | 2017-04-28 | Alkermes Pharma Ireland Ltd | Sulfonamide and sulfinamide prodrugs of fumarates and their use in treating various diseases |
GB201418710D0 (en) | 2014-10-21 | 2014-12-03 | Iron Therapeutics Holdings Ag | Dosage regimen |
US10213411B2 (en) | 2015-08-27 | 2019-02-26 | Vijaykumar Rajasekhar | Use of prodrugs of fumarates in treating heart failure diseases |
US10463642B2 (en) | 2016-02-01 | 2019-11-05 | Vijaykumar Rajasekhar | Methods of treating heart failure diseases using prodrugs of methyl hydrogen fumarate |
BR112019019003A2 (pt) * | 2017-03-13 | 2020-04-14 | Okava Pharmaceuticals Inc | métodos e composições para dispensação de agentes ativos de ácidos micofenólicos a mamíferos não humanos |
WO2022187379A1 (en) | 2021-03-03 | 2022-09-09 | Sana Biotechnology, Inc. | Immunosuppressive therapies for use with cardiomyocyte cell therapies, and associated methods and compositions |
CN114028334B (zh) * | 2021-12-10 | 2023-08-29 | 卓和药业集团股份有限公司 | 一种肺部给药的免疫抑制剂的制备方法 |
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US5135934A (en) * | 1990-07-06 | 1992-08-04 | Du Pont Merck Pharmaceutical Company | 3-phenyl-5,6-dihydrobenz(c) acridine-7-carboxylic acids and related compounds as immunosuppressive agents |
US5372298A (en) * | 1992-01-07 | 1994-12-13 | The Regents Of The University Of California | Transient liquid phase ceramic bonding |
CA2086642C (en) * | 1992-01-09 | 2004-06-15 | Randall E. Morris | Method of treating hyperproliferative vascular disease |
US5516781A (en) * | 1992-01-09 | 1996-05-14 | American Home Products Corporation | Method of treating restenosis with rapamycin |
US5283257A (en) * | 1992-07-10 | 1994-02-01 | The Board Of Trustees Of The Leland Stanford Junior University | Method of treating hyperproliferative vascular disease |
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PL177323B1 (pl) * | 1993-10-01 | 1999-10-29 | Syntex Inc | Kompozycja farmaceutyczna zawierająca mykofenolan mofetylu lub kwas mykofenolowy i sposób wytwarzania kompozycji farmaceutycznej zawierającej mykofenolan mofetylu lub kwas mykofenolowy |
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1997
- 1997-04-01 ID IDP971201A patent/ID18663A/id unknown
- 1997-04-08 BE BE9700319A patent/BE1010963A3/fr not_active IP Right Cessation
- 1997-04-10 DE DE69727559T patent/DE69727559T2/de not_active Expired - Lifetime
- 1997-04-10 DE DE19781690T patent/DE19781690D2/de not_active Expired - Lifetime
- 1997-04-10 AT AT97919330T patent/ATE259228T1/de active
- 1997-04-10 HU HU9903373A patent/HU224919B1/hu active Protection Beyond IP Right Term
- 1997-04-10 EP EP97919330A patent/EP0892640B1/en not_active Expired - Lifetime
- 1997-04-10 AT AT0905997A patent/AT408415B/de not_active IP Right Cessation
- 1997-04-10 IE IE970267A patent/IE970267A1/en not_active IP Right Cessation
- 1997-04-10 MY MYPI97001573A patent/MY119049A/en unknown
- 1997-04-10 RU RU98120360/14A patent/RU2203659C2/ru active
- 1997-04-10 CZ CZ19983267A patent/CZ291811B6/cs not_active IP Right Cessation
- 1997-04-10 RU RU0098120360A patent/RU2615397C2/ru active
- 1997-04-10 AU AU23843/97A patent/AU725388B2/en not_active Expired
- 1997-04-10 NZ NZ332117A patent/NZ332117A/xx not_active IP Right Cessation
- 1997-04-10 TW TW086104578A patent/TW457098B/zh not_active IP Right Cessation
- 1997-04-10 BR BR9708624A patent/BR9708624A/pt not_active IP Right Cessation
- 1997-04-10 DK DK97919330T patent/DK0892640T3/da active
- 1997-04-10 GB GB9821304A patent/GB2326339B/en not_active Expired - Lifetime
- 1997-04-10 AR ARP970101419A patent/AR006583A1/es active IP Right Grant
- 1997-04-10 ES ES97919330T patent/ES2216141T3/es not_active Expired - Lifetime
- 1997-04-10 JP JP53672597A patent/JP3779732B2/ja not_active Expired - Lifetime
- 1997-04-10 IL IL12643197A patent/IL126431A/xx active Protection Beyond IP Right Term
- 1997-04-10 CN CN97193760A patent/CN1104238C/zh not_active Expired - Lifetime
- 1997-04-10 WO PCT/EP1997/001800 patent/WO1997038689A2/en active IP Right Grant
- 1997-04-10 DE DE1997627559 patent/DE122004000038I2/de active Active
- 1997-04-10 CO CO97018556A patent/CO4900024A1/es unknown
- 1997-04-10 EP EP02001803A patent/EP1221316A1/en not_active Withdrawn
- 1997-04-10 US US09/077,398 patent/US6025391A/en not_active Expired - Lifetime
- 1997-04-10 DE DE200412000038 patent/DE122004000038I1/de active Pending
- 1997-04-10 PT PT97919330T patent/PT892640E/pt unknown
- 1997-04-10 GR GR970100135A patent/GR1002893B/el not_active IP Right Cessation
- 1997-04-10 TR TR1998/02056T patent/TR199802056T2/xx unknown
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- 1997-04-11 IT IT97RM000207A patent/IT1297045B1/it active IP Right Grant
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1998
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1999
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2000
- 2000-10-23 US US09/694,209 patent/US6306900B1/en not_active Expired - Lifetime
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2001
- 2001-10-12 CY CY0100032A patent/CY2243B1/xx unknown
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2004
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2005
- 2005-11-09 JP JP2005325141A patent/JP2006063086A/ja active Pending
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2007
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