HUP9903373A2 - Mikofenolátot tartalmazó,bélben oldodó bevonattal ellátott gyógyszerkészítmények - Google Patents
Mikofenolátot tartalmazó,bélben oldodó bevonattal ellátott gyógyszerkészítményekInfo
- Publication number
- HUP9903373A2 HUP9903373A2 HU9903373A HUP9903373A HUP9903373A2 HU P9903373 A2 HUP9903373 A2 HU P9903373A2 HU 9903373 A HU9903373 A HU 9903373A HU P9903373 A HUP9903373 A HU P9903373A HU P9903373 A2 HUP9903373 A2 HU P9903373A2
- Authority
- HU
- Hungary
- Prior art keywords
- mycophenolate
- enteric
- pharmaceutical compositions
- coated pharmaceutical
- diseases
- Prior art date
Links
- HPNSFSBZBAHARI-RUDMXATFSA-N mycophenolic acid Chemical group OC1=C(C\C=C(/C)CCC(O)=O)C(OC)=C(C)C2=C1C(=O)OC2 HPNSFSBZBAHARI-RUDMXATFSA-N 0.000 title abstract 3
- HPNSFSBZBAHARI-UHFFFAOYSA-N micophenolic acid Natural products OC1=C(CC=C(C)CCC(O)=O)C(OC)=C(C)C2=C1C(=O)OC2 HPNSFSBZBAHARI-UHFFFAOYSA-N 0.000 title abstract 2
- 229940014456 mycophenolate Drugs 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 238000002360 preparation method Methods 0.000 abstract 2
- 208000023275 Autoimmune disease Diseases 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 239000002702 enteric coating Substances 0.000 abstract 1
- 238000009505 enteric coating Methods 0.000 abstract 1
- 210000001035 gastrointestinal tract Anatomy 0.000 abstract 1
- 208000026278 immune system disease Diseases 0.000 abstract 1
- 230000001506 immunosuppresive effect Effects 0.000 abstract 1
- 210000000056 organ Anatomy 0.000 abstract 1
- 238000002054 transplantation Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A61K38/13—Cyclosporins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4891—Coated capsules; Multilayered drug free capsule shells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
Abstract
A találmány tárgyát mikofenolátot tartalmazó készítmény, ennekalkalmazása képezi, azzal jellemezve, hogy a mikofenolátsók bélbenoldódó bevonattal vannak ellátva. Ezzel biztosítható, hogy a hatóanyaga bélrendszer felső részében szabaduljon fel. A készítmények,különösen immunszuppresszív indikációk esetében, főként a szerv,szövet vagy sejt allograft vagy xenograft (például átültetés utáni)kilökődése vagy immunrendszeri eredetű betegségek(autoimmunbetegségek) ellen hatásosak. Ó
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9607564.3A GB9607564D0 (en) | 1996-04-12 | 1996-04-12 | Organic compounds |
GBGB9622028.0A GB9622028D0 (en) | 1996-10-24 | 1996-10-24 | Organic compounds |
PCT/EP1997/001800 WO1997038689A2 (en) | 1996-04-12 | 1997-04-10 | Enteric-coated pharmaceutical compositions of mycophenolate |
Publications (3)
Publication Number | Publication Date |
---|---|
HUP9903373A2 true HUP9903373A2 (hu) | 2001-04-28 |
HUP9903373A3 HUP9903373A3 (en) | 2001-05-28 |
HU224919B1 HU224919B1 (en) | 2006-04-28 |
Family
ID=26309105
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU9903373A HU224919B1 (en) | 1996-04-12 | 1997-04-10 | Enteric-coated pharmaceutical compositions of mycophenolate |
Country Status (34)
Country | Link |
---|---|
US (3) | US6025391A (hu) |
EP (2) | EP1221316A1 (hu) |
JP (2) | JP3779732B2 (hu) |
CN (1) | CN1104238C (hu) |
AR (2) | AR006583A1 (hu) |
AT (2) | AT408415B (hu) |
AU (1) | AU725388B2 (hu) |
BE (1) | BE1010963A3 (hu) |
BR (1) | BR9708624A (hu) |
CO (1) | CO4900024A1 (hu) |
CY (1) | CY2243B1 (hu) |
CZ (1) | CZ291811B6 (hu) |
DE (4) | DE69727559T2 (hu) |
DK (1) | DK0892640T3 (hu) |
ES (2) | ES2178510B1 (hu) |
FR (1) | FR2747920B1 (hu) |
GB (1) | GB2326339B (hu) |
GR (1) | GR1002893B (hu) |
HK (2) | HK1051484A1 (hu) |
HU (1) | HU224919B1 (hu) |
ID (1) | ID18663A (hu) |
IE (1) | IE970267A1 (hu) |
IL (1) | IL126431A (hu) |
IT (1) | IT1297045B1 (hu) |
LU (1) | LU91094I2 (hu) |
MY (1) | MY119049A (hu) |
NL (1) | NL300157I2 (hu) |
NO (2) | NO322891B1 (hu) |
NZ (1) | NZ332117A (hu) |
PT (1) | PT892640E (hu) |
RU (2) | RU2615397C2 (hu) |
TR (1) | TR199802056T2 (hu) |
TW (1) | TW457098B (hu) |
WO (1) | WO1997038689A2 (hu) |
Families Citing this family (47)
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EP1181034B1 (en) * | 1999-05-10 | 2010-07-21 | Paolo Brenner | Combinations of immunosuppressive agents for the treatment or prevention of graft rejections |
US20030050692A1 (en) * | 2000-12-22 | 2003-03-13 | Avantec Vascular Corporation | Delivery of therapeutic capable agents |
GB0124953D0 (en) * | 2001-10-17 | 2001-12-05 | Novartis Ag | Organic Compounds |
DK1435910T3 (da) * | 2001-10-19 | 2009-11-09 | Isotechnika Inc | Nye cyclosporinanaloge mikroemulsionsprækoncentrater |
GB0301259D0 (en) | 2003-01-20 | 2003-02-19 | Novartis Ag | Organic compounds |
GB0314553D0 (en) * | 2003-06-21 | 2003-07-30 | Weatherford Lamb | Electric submersible pumps |
US8993599B2 (en) * | 2003-07-18 | 2015-03-31 | Santarus, Inc. | Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them |
AR045957A1 (es) * | 2003-10-03 | 2005-11-16 | Novartis Ag | Composicion farmaceutica y combinacion |
PT1729797E (pt) * | 2004-03-22 | 2008-12-17 | Solvay Pharm Gmbh | Composições farmacêuticas orais de produtos contendo lipase, em particular de pancreatina, contendo tensioactivos |
JP2007532585A (ja) | 2004-04-26 | 2007-11-15 | テバ ジョジセルジャール ザ−トケルエン ムケド レ−スベニュタ−ルシャシャ−グ | ミコフェノール酸及びそのエステル誘導体の調製方法 |
WO2005105769A2 (en) | 2004-04-27 | 2005-11-10 | Teva Gyógyszergyár Zàrtköruen Muködo Rèszvènytàrsasàg - | Mycophenolate mofetil impurity |
CA2573781A1 (en) | 2004-07-20 | 2006-02-02 | Teva Gyogyszergyar Zartkoruen Mukodo Reszvenytarsasag | Processes for preparation of crystalline mycophenolate sodium |
GB0419355D0 (en) * | 2004-08-31 | 2004-09-29 | Novartis Ag | Organic compounds |
US20060235070A1 (en) * | 2005-02-08 | 2006-10-19 | Hayden Michael R | Compositions and methods for treating vascular, autoimmune, and inflammatory diseases |
US20060235009A1 (en) * | 2005-02-08 | 2006-10-19 | Richard Glickman | Treatment of vascular, autoimmune and inflammatory diseases using low dosages of IMPDH inhibitors |
PL2278002T3 (pl) * | 2005-07-29 | 2017-12-29 | Abbott Laboratories Gmbh | Pankreatyna o zmniejszonej zawartości wirusowej |
US11266607B2 (en) | 2005-08-15 | 2022-03-08 | AbbVie Pharmaceuticals GmbH | Process for the manufacture and use of pancreatin micropellet cores |
US9198871B2 (en) * | 2005-08-15 | 2015-12-01 | Abbott Products Gmbh | Delayed release pancreatin compositions |
CN1985994B (zh) * | 2005-12-19 | 2011-01-12 | 康泰乐(北京)医药科技发展有限公司 | 改进的包含霉酚酸盐的包有肠溶衣的药物组合物 |
CN101378749A (zh) * | 2006-02-13 | 2009-03-04 | 诺瓦提斯公司 | 高剂量的麦考酚酸(mpa) |
JP2007230948A (ja) * | 2006-03-02 | 2007-09-13 | Univ Meijo | 腸溶性化硬カプセル |
US10072256B2 (en) * | 2006-05-22 | 2018-09-11 | Abbott Products Gmbh | Process for separating and determining the viral load in a pancreatin sample |
KR20080069571A (ko) * | 2006-06-29 | 2008-07-28 | 테바 파마슈티컬 인더스트리즈 리미티드 | 산 대사산물 생성의 조절 |
US20080176937A1 (en) * | 2007-01-23 | 2008-07-24 | Apotex Fermentation Inc. | Novel crystalline mycophenolate sodium polymorph and processes to manufacture same |
US20080182998A1 (en) * | 2007-01-25 | 2008-07-31 | Apotex Fermentation Inc. | Novel crystalline mycophenolate sodium polymorph and processes to manufacture same |
US20080254520A1 (en) * | 2007-04-11 | 2008-10-16 | Eva Gulyas | Method for reducing impurity level in mycophenolic acid fermentation |
MX2010001711A (es) | 2007-08-13 | 2010-03-11 | Panacea Biotec Ltd | Composiciones de liberacion extendida que comprenden micofenolato sodico y procedimientos de las mismas. |
US20090130063A1 (en) * | 2007-11-15 | 2009-05-21 | Solvay Pharmaceuticals Gmbh | Process for separating and determining the viral load in a pancreatin sample |
JP2011527339A (ja) * | 2008-07-09 | 2011-10-27 | アスプレバ インターナショナル リミテッド | 眼障害を処置するためのミコフェノール酸ナトリウムのpH特異的な溶液 |
EP2488173A1 (en) * | 2009-10-13 | 2012-08-22 | Teva Pharmaceutical Industries Ltd. | Delayed release compositions |
US20110086102A1 (en) * | 2009-10-13 | 2011-04-14 | Teva Pharmaceutical Industries Ltd. | Delayed release compositions |
WO2011051967A2 (en) * | 2009-10-23 | 2011-05-05 | Alkem Laboratories Ltd | Pharmaceutical compositions comprising mycophenolate and processes for preparing thereof |
CN103880799A (zh) * | 2010-11-16 | 2014-06-25 | 北京京卫信康医药科技发展有限公司 | 麦考酚酸钠的新晶型及其制备方法 |
CN103880800A (zh) * | 2010-11-16 | 2014-06-25 | 北京京卫信康医药科技发展有限公司 | 麦考酚酸钠的新晶型及其制备方法 |
GB201100786D0 (en) | 2011-01-18 | 2011-03-02 | Ems Sa | Pharmaceutical compositions of immunosuppressants |
WO2013041205A1 (de) | 2011-09-19 | 2013-03-28 | Pyxirion Pharma Gmbh | Neue therapeutische konzepte zur behandlung von gefässerkrankungen |
UA116648C2 (uk) | 2013-03-14 | 2018-04-25 | Алкермес Фарма Айерленд Лімітед | Фумарати як проліки та їх застосування при лікуванні різних захворювань |
US8669281B1 (en) | 2013-03-14 | 2014-03-11 | Alkermes Pharma Ireland Limited | Prodrugs of fumarates and their use in treating various diseases |
WO2014167442A1 (en) | 2013-03-26 | 2014-10-16 | Wockhardt Limited | Pharmaceutical compositions comprising mycophenolic acid or salts thereof |
US10179120B2 (en) | 2014-01-06 | 2019-01-15 | Iron Therapeutics Holdings Ag | Dosage regimen of ferric trimaltol |
WO2015127450A1 (en) | 2014-02-24 | 2015-08-27 | Alkermes Pharma Ireland Limited | Sulfonamide and sulfinamide prodrugs of fumarates and their use in treating various diseases |
GB201418710D0 (en) | 2014-10-21 | 2014-12-03 | Iron Therapeutics Holdings Ag | Dosage regimen |
US10213411B2 (en) | 2015-08-27 | 2019-02-26 | Vijaykumar Rajasekhar | Use of prodrugs of fumarates in treating heart failure diseases |
US10463642B2 (en) | 2016-02-01 | 2019-11-05 | Vijaykumar Rajasekhar | Methods of treating heart failure diseases using prodrugs of methyl hydrogen fumarate |
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IL305524A (en) | 2021-03-03 | 2023-10-01 | Sana Biotechnology Inc | Immunosuppressive treatments for use with cardiomyocyte cell treatments, and associated methods and preparations |
CN114028334B (zh) * | 2021-12-10 | 2023-08-29 | 卓和药业集团股份有限公司 | 一种肺部给药的免疫抑制剂的制备方法 |
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1997
- 1997-04-01 ID IDP971201A patent/ID18663A/id unknown
- 1997-04-08 BE BE9700319A patent/BE1010963A3/fr not_active IP Right Cessation
- 1997-04-10 HU HU9903373A patent/HU224919B1/hu active Protection Beyond IP Right Term
- 1997-04-10 AT AT0905997A patent/AT408415B/de not_active IP Right Cessation
- 1997-04-10 RU RU0098120360A patent/RU2615397C2/ru active
- 1997-04-10 ES ES009850018A patent/ES2178510B1/es not_active Expired - Fee Related
- 1997-04-10 WO PCT/EP1997/001800 patent/WO1997038689A2/en active IP Right Grant
- 1997-04-10 GR GR970100135A patent/GR1002893B/el not_active IP Right Cessation
- 1997-04-10 AT AT97919330T patent/ATE259228T1/de active
- 1997-04-10 DK DK97919330T patent/DK0892640T3/da active
- 1997-04-10 US US09/077,398 patent/US6025391A/en not_active Expired - Lifetime
- 1997-04-10 CZ CZ19983267A patent/CZ291811B6/cs not_active IP Right Cessation
- 1997-04-10 MY MYPI97001573A patent/MY119049A/en unknown
- 1997-04-10 TR TR1998/02056T patent/TR199802056T2/xx unknown
- 1997-04-10 DE DE69727559T patent/DE69727559T2/de not_active Expired - Lifetime
- 1997-04-10 PT PT97919330T patent/PT892640E/pt unknown
- 1997-04-10 CO CO97018556A patent/CO4900024A1/es unknown
- 1997-04-10 RU RU98120360/14A patent/RU2203659C2/ru active
- 1997-04-10 AR ARP970101419A patent/AR006583A1/es active IP Right Grant
- 1997-04-10 EP EP02001803A patent/EP1221316A1/en not_active Withdrawn
- 1997-04-10 ES ES97919330T patent/ES2216141T3/es not_active Expired - Lifetime
- 1997-04-10 JP JP53672597A patent/JP3779732B2/ja not_active Expired - Lifetime
- 1997-04-10 NZ NZ332117A patent/NZ332117A/xx not_active IP Right Cessation
- 1997-04-10 DE DE200412000038 patent/DE122004000038I1/de active Pending
- 1997-04-10 DE DE1997627559 patent/DE122004000038I2/de active Active
- 1997-04-10 DE DE19781690T patent/DE19781690D2/de not_active Expired - Lifetime
- 1997-04-10 EP EP97919330A patent/EP0892640B1/en not_active Expired - Lifetime
- 1997-04-10 AU AU23843/97A patent/AU725388B2/en not_active Expired
- 1997-04-10 CN CN97193760A patent/CN1104238C/zh not_active Expired - Lifetime
- 1997-04-10 BR BR9708624A patent/BR9708624A/pt not_active IP Right Cessation
- 1997-04-10 TW TW086104578A patent/TW457098B/zh not_active IP Right Cessation
- 1997-04-10 GB GB9821304A patent/GB2326339B/en not_active Expired - Lifetime
- 1997-04-10 IL IL12643197A patent/IL126431A/xx active Protection Beyond IP Right Term
- 1997-04-10 IE IE970267A patent/IE970267A1/en not_active IP Right Cessation
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