AP983A - Freeze-dried composition of bone morphogenetic protein human MP52. - Google Patents

Freeze-dried composition of bone morphogenetic protein human MP52. Download PDF

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Publication number
AP983A
AP983A APAP/P/1999/001602A AP9901602A AP983A AP 983 A AP983 A AP 983A AP 9901602 A AP9901602 A AP 9901602A AP 983 A AP983 A AP 983A
Authority
AP
ARIPO
Prior art keywords
bone morphogenetic
morphogenetic factor
factor human
mannitol
composition
Prior art date
Application number
APAP/P/1999/001602A
Other languages
English (en)
Other versions
AP9901602A0 (en
Inventor
Hideki Ichikawa
Mitsuko Inagaki
Original Assignee
Biopharm Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biopharm Gmbh filed Critical Biopharm Gmbh
Publication of AP9901602A0 publication Critical patent/AP9901602A0/xx
Application granted granted Critical
Publication of AP983A publication Critical patent/AP983A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18Growth factors; Growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18Growth factors; Growth regulators
    • A61K38/1875Bone morphogenic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Dermatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Molecular Biology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Biochemistry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
APAP/P/1999/001602A 1997-01-30 1998-01-29 Freeze-dried composition of bone morphogenetic protein human MP52. AP983A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP1634997 1997-01-30
PCT/JP1998/000371 WO1998033514A1 (fr) 1997-01-30 1998-01-29 Composition lyophilisee de mp52 humaine de proteines morphogenetiques osseuses

Publications (2)

Publication Number Publication Date
AP9901602A0 AP9901602A0 (en) 1999-09-30
AP983A true AP983A (en) 2001-07-16

Family

ID=11913900

Family Applications (1)

Application Number Title Priority Date Filing Date
APAP/P/1999/001602A AP983A (en) 1997-01-30 1998-01-29 Freeze-dried composition of bone morphogenetic protein human MP52.

Country Status (22)

Country Link
EP (1) EP0972520B9 (da)
JP (1) JP4209948B2 (da)
KR (1) KR100548107B1 (da)
CN (1) CN1152712C (da)
AP (1) AP983A (da)
AT (1) ATE302021T1 (da)
AU (1) AU737595B2 (da)
BR (1) BR9807537B1 (da)
CA (1) CA2278546C (da)
DE (1) DE69831223T9 (da)
DK (1) DK0972520T3 (da)
EA (1) EA001579B1 (da)
ES (1) ES2244043T3 (da)
HU (1) HU226554B1 (da)
IL (2) IL130967A0 (da)
NO (1) NO322334B1 (da)
NZ (1) NZ336509A (da)
PL (1) PL189381B1 (da)
RS (1) RS49691B (da)
SI (1) SI0972520T1 (da)
TR (1) TR199901832T2 (da)
WO (1) WO1998033514A1 (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6281195B1 (en) 1997-02-07 2001-08-28 Stryker Corporation Matrix-free osteogenic devices, implants and methods of use thereof
US20050053596A1 (en) * 2001-10-09 2005-03-10 Stringer Bradley Michael John Therapeutic biological product and method for formation of new vascularised bone
AU2002308204B9 (en) 2001-11-19 2008-06-12 Scil Technology Gmbh Device having osteoinductive and osteoconductive properties
DK1539261T3 (da) 2002-09-10 2006-08-07 Scil Technology Gmbh Metalimplantat belagt under nedsat oxygenkoncentration med osteoinduktiv protein
JP2007501223A (ja) * 2003-08-05 2007-01-25 フジ フォト フィルム ビー.ブイ. 安定剤としての組換え又は合成ゼラチンのワクチン中の使用
AU2004288854B2 (en) * 2003-11-10 2009-10-01 Arriva-Pharmaceuticals, Inc. Dry recombinant human alpha 1-antitrypsin formulation
DE602005022998D1 (de) 2004-03-10 2010-09-30 Scil Technology Gmbh Überzogene implantate, ihre herstellung und verwendung davon
US20160344677A1 (en) 2015-05-22 2016-11-24 Microsoft Technology Licensing, Llc Unified messaging platform for providing interactive semantic objects
US10360287B2 (en) 2015-05-22 2019-07-23 Microsoft Technology Licensing, Llc Unified messaging platform and interface for providing user callouts

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996033215A1 (fr) * 1995-04-19 1996-10-24 Hoechst Pharmaceuticals & Chemicals K.K. Proteine nouvelle et son procede de fabrication

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3273597D1 (en) * 1981-11-28 1986-11-06 Sunstar Kk Pharmaceutical composition containing interferon in stable state
US5037644A (en) * 1986-10-27 1991-08-06 Cetus Corporation Pharmaceutical compositions of recombinant interleukin-2 and formulation processes
JP3351525B2 (ja) * 1991-06-21 2002-11-25 ジェネティックス・インスティテュート・インコーポレイテッド 骨形成性蛋白医薬処方物
JP2966592B2 (ja) * 1991-07-20 1999-10-25 萩原 義秀 安定化されたヒトモノクローナル抗体製剤
CZ287715B6 (en) * 1992-02-12 2001-01-17 Bioph Biotech Entw Pharm Gmbh DNA sequence, recombinant DNA molecule containing thereof, process for preparing protein from the group of TGF-beta substances, pharmaceutical preparation containing such protein, antibody or fragment thereof and its use
CA2093836A1 (en) * 1992-04-24 1993-10-25 Wayne Gombotz Biodegradable tgf-.beta. delivery system for bone regeneration
DE4239877C1 (de) * 1992-11-27 1994-03-17 Boehringer Ingelheim Int Stabilisierte Superoxid-Dismutase (SOD)-Zusammensetzung
AU707796B2 (en) * 1995-03-21 1999-07-22 Merck Serono Sa HCG liquid formulations

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996033215A1 (fr) * 1995-04-19 1996-10-24 Hoechst Pharmaceuticals & Chemicals K.K. Proteine nouvelle et son procede de fabrication

Also Published As

Publication number Publication date
WO1998033514A1 (fr) 1998-08-06
AU5679198A (en) 1998-08-25
ES2244043T3 (es) 2005-12-01
IL130967A0 (en) 2001-01-28
BR9807537B1 (pt) 2009-01-13
HU226554B1 (en) 2009-03-30
EP0972520A4 (en) 2002-11-05
AU737595B2 (en) 2001-08-23
NZ336509A (en) 2001-03-30
SI0972520T1 (sl) 2006-02-28
CA2278546C (en) 2008-04-01
EP0972520A1 (en) 2000-01-19
HUP0002386A2 (hu) 2000-11-28
DE69831223T9 (de) 2006-12-07
NO993702D0 (no) 1999-07-29
EA199900694A1 (ru) 2000-04-24
CN1244127A (zh) 2000-02-09
YU34999A (sh) 2002-08-12
NO322334B1 (no) 2006-09-18
HUP0002386A3 (en) 2002-09-30
IL130967A (en) 2006-12-10
RS49691B (sr) 2007-12-31
EP0972520B9 (en) 2006-03-22
CA2278546A1 (en) 1998-08-06
BR9807537A (pt) 2000-03-21
PL189381B1 (pl) 2005-07-29
DE69831223T2 (de) 2006-02-16
DE69831223D1 (de) 2005-09-22
EP0972520B1 (en) 2005-08-17
EA001579B1 (ru) 2001-06-25
KR100548107B1 (ko) 2006-02-02
DK0972520T3 (da) 2005-12-19
PL334852A1 (en) 2000-03-27
JP4209948B2 (ja) 2009-01-14
KR20000070586A (ko) 2000-11-25
ATE302021T1 (de) 2005-09-15
NO993702L (no) 1999-09-29
AP9901602A0 (en) 1999-09-30
TR199901832T2 (xx) 1999-12-21
CN1152712C (zh) 2004-06-09

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